Table 2 Clinical outcome at 6, 12, and 24 months after treatment
From: Clinical manifestations and pathological correlation of immunoglobulin A nephropathy in children
Clinical | At diagnosis (n = 47) | 6 months (n = 37) | 12 months (n = 33) | 24 months (n = 25) |
|---|---|---|---|---|
Median serum creatinine (mg/dL) (IQR) | 0.60 (0.5,1.5) | 0.60 (0.48,1.02) | 0.60 (0.45,0.74) | 0.63 (0.5,1.0) |
Median eGFR (mL/min/1.73m2) | 97.8 | 105.7 | 104.7 | 98.8 |
Hypertension (%) | 44.7 | 27 | 18.2 | 28 |
Edema (%) | 42.6 | 13.5 | 6.1 | 8 |
Microscopic hematuria (%) | 63.8 | 45.9 | 42.4 | 52 |
Gross hematuria (%) | 21.3 | 0 | 0 | 0 |
Significant proteinuria (%) | 46.8 | 70.3 | 63.6 | 48 |
Nephrotic range proteinuria (%) | 46.8 | 16.2 | 12.1 | 24 |
AKI/Rapidly progressive glomerulonephritis (%) | 29.8 | 2.7 | 0 | 0 |
Chronic kidney disease (%) | 0 | 18.9 | 15.2 | 24 |