Table 2 Comparison of effects of cyclosporine A and tacrolimus on anthropometric measurements
From: The effect of calcineurin inhibitors on anthropometric measurements in kidney transplant recipients
| Â | Pre-transplant | 1st month | 3rd month | 6th month | 12th month | 24th month | 36th month | 48th month | |
|---|---|---|---|---|---|---|---|---|---|
Variables | CsA (n) | 60 | 60 | 60 | 60 | 60 | 60 | 56 | 55 |
Tac (n) | 68 | 68 | 68 | 68 | 68 | 68 | 60 | 56 | |
Body weight (kg) | CsA | 63.5 ± 11.9 | 63.1 ± 12.3 | 65.4 ± 12.0* | 67.2 ± 12.9** | 67.8 ± 13.4** | 69.2 ± 14.4** | 69.9 ± 15.4** | 70.9 ± 15.7** |
Tac | 62.7 ± 15.3 | 62.1 ± 14.3 | 64.9 ± 14.1* | 66.0 ± 15.0** | 67.1 ± 16.1** | 68.2 ± 17.1** | 71.1 ± 19.1** | 72.8 ± 18.9** | |
Body mass index (kg/m2) | CsA | 24.0 ± 4.4 | 23.8 ± 4.4 | 24.7 ± 4.2* | 25.3 ± 4.4** | 25.5 ± 4.6** | 26.1 ± 5.1** | 26.4 ± 5.4** | 26.8 ± 5.6** |
Tac | 23.7 ± 4.8 | 23.4 ± 4.3 | 24.5 ± 4.3* | 24.9 ± 4.5** | 25.3 ± 4.8** | 25.7 ± 5.1** | 27.0 ± 5.8** | 27.7 ± 5.9** | |
Body fat percentage (%) | CsA | 23.4 ± 7.8 | 23.1 ± 8.3 | 24.8 ± 8.7* | 25.0 ± 8.7* | 25.1 ± 9.1* | 25.3 ± 8.9* | 25.7 ± 10.0* | 27.0 ± 9.6** |
Tac | 23.7 ± 9.9 | 23.3 ± 10.1 | 24.6 ± 9.3 | 24.9 ± 9.3 | 25.1 ± 9.8 | 26.0 ± 10.4* | 27.6 ± 11.1* | 27.3 ± 10.8* | |
Waist circumference (cm) | CsA | 85.5 ± 10.9 | 89.1 ± 11.4* | 90.6 ± 11.5** | 91.7 ± 12.3** | 90.4 ± 13.3** | 91.3 ± 14.1** | 91.9 ± 15.7** | 91.6 ± 17.3** |
Tac | 84.7 ± 12.9 | 86.4 ± 11.8* | 88.5 ± 12.1** | 89.5 ± 12.2** | 88.7 ± 13.5** | 88.5 ± 15.5* | 90.3 ± 16.8** | 92.3 ± 16.1** | |
Hip circumference (cm) | CsA | 93.8 ± 10.0 | 95.7 ± 9.1* | 97.4 ± 9.1* | 98.9 ± 9.3** | 100.0 ± 9.8** | 100.8 ± 9.7** | 100.8 ± 10.0** | 100.6 ± 9.8** |
Tac | 94.8 ± 9.6 | 94.9 ± 9.1* | 97.0 ± 9.1* | 98.5 ± 9.4** | 99.0 ± 10.1** | 98.5 ± 9.9** | 99.7 ± 9.9** | 100.9 ± 11.0** | |
Waist-to-hip ratio | CsA | 0.91 ± 0.06 | 0.93 ± 0.07* | 0.92 ± 0.06* | 0.92 ± 0.07 | 0.90 ± 0.07 | 0.90 ± 0.08 | 0.90 ± 0.10 | 0.90 ± 0.11 |
Tac | 0.89 ± 0.08 | 0.90 ± 0.07* | 0.91 ± 0.06* | 0.90 ± 0.06* | 0.89 ± 0.07 | 0.89 ± 0.09 | 0.90 ± 0.11 | 0.91 ± 0.10 | |
Wrist circumference (cm) | CsA | 16.7 ± 1.3 | 16.5 ± 1.4 | 16.7 ± 1.3 | 16.8 ± 1.5 | 16.8 ± 1.7 | 16.7 ± 1.5 | 16.3 ± 1.5 | 16.1 ± 1.2** |
Tac | 16.3 ± 1.7 | 16.4 ± 1.7 | 16.7 ± 1.6* | 16.6 ± 1.5* | 16.5 ± 1.6 | 16.3 ± 1.6 | 16.1 ± 1.6 | 15.9 ± 1.6* | |
Neck circumference (cm) | CsA | 35.7 ± 2.7 | 37.0 ± 2.8** | 37.5 ± 2.9** | 37.1 ± 3.2** | 36.7 ± 3.4* | 36.4 ± 3.3* | 35.9 ± 3.4 | 35.2 ± 3.4 |
Tac | 35.3 ± 3.6 | 36.9 ± 3.3** | 37.1 ± 3.3** | 36.8 ± 3.3** | 36.5 ± 3.6** | 35.9 ± 4.0 | 35.6 ± 4.0 | 35.6 ± 4.6 | |