| Without AKI | With AKI | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Groups | CTL | ER | TR | IF | HF | CTL | ER | TR | IF | HF |
Parameters | ||||||||||
Serum Urea (mg/dl) | 70.83 ± 3.37 | 97.01 ± 5.35 | 83.01 ± 6.02 | 67.02 ± 4.85 | 60.33 ± 4.18 | 312 ± 10.51*** | 253.66 ± 6.88†††| 204 ± 10.7###, ## | 241 ± 15.22^^^ | 383.5 ± 14.38&&& |
Serum Creatinine (mg/dl) | 0.45 ± 0.03 | 0.57 ± 0.01 | 0.53 ± 0.02 | 0.54 ± 0.03 | 0.61 ± 0.07 | 3.38 ± 0.14*** | 2.3 ± 0.15 †††, ††| 1.76 ± 0.1 ###, ## | 2.86 ± 0.07^^^, ^ | 3.88 ± 0.17& |
Urine Albumin excretion (mg/24 h) | 0.51 ± 0.17 | 0.58 ± 0.15 | 0.41 ± 0.15 | 0.5 ± 0.18 | 0.75 ± 0.17 | 28.16 ± 1.92*** | 24.5 ± 1.97††| 16.66 ± 0.8###, # | 22.3 ± 0.66^^^, ^ | 31.83 ± 2.5 |
eGFR (ml/min/100 g bw) | 0.52 ± 0.01 | 0.48 ± 0.02 | 0.52 ± 0.02 | 0.52 ± 0.02 | 0.49 ± 0.02 | 0.1 ± 0.007*** | 0.18 ± 0.004†| 0.26 ± 0.008###, # | 0.11 ± 0.01 | 0.1 ± 0.004 |
Body weight (g) | 244 ± 4.84 | 193 ± 3.43ΩΩΩ | 261 ± 5.13 | 238 ± 5.32 | 285 ± 5.49ΦΦΦ | 245 ± 4.43 | 192 ± 2.34 | 257 ± 4.11 | 240 ± 4.62 | 286 ± 5.07 |
Kidney weight (g) | 1.008 ± 0.024 | 0.74 ± 0.023ΩΩΩ | 1.001 ± 0.042 | 0.916 ± 0.036 | 1.188 ± 0.029ΦΦΦ | 1.443 ± 0.031*** | 1.051 ± 0.035 | 1.373 ± 0.034 | 1.361 ± 0.027 | 1.776 ± 0.043 |
KW/BW ratio | 0.41 ± 0.013 | 0.38 ± 0.008 | 0.38 ± 0.016 | 0.38 ± 0.015 | 0.41 ± 0.009 | 0.59 ± 0.01*** | 0.54 ± 0.016††| 0.53 ± 0.014## | 0.57 ± 0.015 | 0.62 ± 0.015 |