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Table 2 Risk factors of post-ECMO AKI determined by multivariate analysis with backward stepwise

From: Independent risk factors of acute kidney injury among patients receiving extracorporeal membrane oxygenation

 

Univariate

 

Multivariate

OR

95% CI

P Value

 

OR

95% CI

P Value

Age

1.00

0.97–1.03

0.93

    

Male

1.19

0.38–3.74

0.77

    

APACHE II score

1.13

1.06–1.20

< 0.001

    

SOFA score

1.47

1.22–1.77

< 0.001

 

1.41

1.16–1.71

0.001

Creatinine before ECMO initiation

1.00

0.98–1.03

0.91

    

Creatinine at 24 h after ECMO initiation

1.07

1.04–1.11

< 0.001

    

Creatinine at 48 h after ECMO initiation

1.06

1.03–1.09

< 0.001

    

BUN at 24 h after ECMO initiation

1.33

1.17–1.52

< 0.001

    

BUN at 48 h after ECMO initiation

1.16

1.04–1.30

0.006

    

Lactate before ECMO initiation

1.13

1.04–1.23

0.004

    

Lactate at 24 h after ECMO initiation

1.20

1.08–1.33

0.001

 

1.27

1.09–1.47

0.002

Lactate at 48 h after ECMO initiation

1.49

1.10–2.03

0.01

    

LVEF before ECMO initiation

0.94

0.91–0.98

0.001

 

0.80

0.70–0.90

< 0.001

LVEF at 24 h after ECMO initiation

0.94

0.90–0.99

0.02

    

LVEF at 48 h after ECMO initiation

0.96

0.92-1.00

0.04

    
  1. Abbreviations: LVEF, left ventricular ejection fraction; APACHE II score, acute physiology and chronic health evaluation II score; SOFA score, sequential organ failure assessment score; ECMO, extracorporeal membrane oxygenation