Skip to content


Case Reports

This section welcomes submissions of case reports only.

Page 1 of 3

  1. Content type: Case report

    Renal thrombotic microangiopathy (TMA) is occasionally seen in biopsies with pauci-immune necrotizing crescentic glomerulonephritis (PCGN). Recent study indicated that the complement activation is more promine...

    Authors: Jianling Tao, Jonathan Lieberman, Richard A. Lafayette and Neeraja Kambham

    Citation: BMC Nephrology 2018 19:355

    Published on:

  2. Content type: Case report

    Baclofen is a centrally acting GABAB receptor agonist and it is used widely for the treatment of spasticity, persistent hiccups and multiple sclerosis. The renal system is the main route of excretion, thus people...

    Authors: Emad Khazneh, Alaa Shamlawi, Kamel Jebrin, Zakaria Hamdan and Osama Sawalmeh

    Citation: BMC Nephrology 2018 19:352

    Published on:

  3. Content type: Case report

    Maternally inherited diabetes and deafness (MIDD), a mitochondrial genetic disorder, typically affects the kidneys and results in end-stage renal disease. Early diagnosis of MIDD is challenging when renal mani...

    Authors: Keiji Sugai, Hiroyuki Ueda, Keita Morimoto, Mai Tanaka, Daisuke Takahashi, Akio Nakashima, Junichiro Kato, Hiroshi Takahashi, Yutaka Yamaguchi, Tetsuya Kawamura, Kazushige Hanaoka, Yoichi Miyazaki and Takashi Yokoo

    Citation: BMC Nephrology 2018 19:350

    Published on:

  4. Content type: Case report

    Post-transplant diabetes mellitus (PTDM) is an emerging problem in kidney transplantation, representing an important risk factor for kidney function loss. Diabetic nephropathy (DN) occurrence in transplanted k...

    Authors: Marilena Gregorini, Vincenzo Sepe, Francesca Eleonora Pattonieri, Anna Allesina and Teresa Rampino

    Citation: BMC Nephrology 2018 19:348

    Published on:

  5. Content type: Case report

    Peritoneal dialysis (PD)-associated infection caused by Mycobacterium spp. is rare. Mycobacterium abscessus is one of the most resistant acid-fast bacteria, and treatment is also the most difficult and refractory...

    Authors: Ryuichi Yoshimura, Miharu Kawanishi, Shungo Fujii, Aska Yamauchi, Kentaro Takase, Kaori Yoshikane, Masahiro Egawa, Hiroaki Shiina and Takafumi Ito

    Citation: BMC Nephrology 2018 19:341

    Published on:

  6. Content type: Case report

    Immunoglobulin heavy-and-light-chain amyloidosis (AHL amyloidosis) is a newly established disease entity where both the immunoglobulin heavy-chain and light-chain compose amyloid fibrils. The immunoglobulins r...

    Authors: Shun Manabe, Chihiro Iwasaki, Michiyasu Hatano, Fuyuki Kametani, Masahide Yazaki, Kosaku Nitta and Michio Nagata

    Citation: BMC Nephrology 2018 19:337

    Published on:

  7. Content type: Case report

    IgG4-related disease (IgG4-RD) is a newly recognized fibroinflammatory condition. The kidney is one of the organs commonly affected by IgG4-RD. Tubulointerstitial nephritis (TIN) is the main feature, and membr...

    Authors: Atsushi Kitazawa, Ryo Koda, Atsunori Yoshino, Yoshihiko Ueda and Tetsuro Takeda

    Citation: BMC Nephrology 2018 19:330

    Published on:

  8. Content type: Case report

    Acyclovir is one of the most common prescribed antiviral drugs. Acyclovir nephrotoxicity occurs in approximately 12–48% of cases. It can present in clinical practice as acute kidney injury (AKI), crystal-induc...

    Authors: Jonathan S. Chávez-Iñiguez, Ramón Medina-Gonzalez, Lilia Aguilar-Parra, Eduardo J. Torres-Vázquez, Pablo Maggiani-Aguilera, Enrique Cervantes-Pérez and Guillermo García-García

    Citation: BMC Nephrology 2018 19:324

    Published on:

  9. Content type: Case report

    Monoclonal gammopathy of renal significance (MGRS) is a recently defined group of renal diseases caused by monoclonal immunoglobulin secreted by nonmalignant proliferative B cell or plasma cell. Monoclonal imm...

    Authors: Xiao-juan Yu, Xu-jie Zhou, Su-xia Wang, Fu-de Zhou and Ming-hui Zhao

    Citation: BMC Nephrology 2018 19:322

    Published on:

  10. Content type: Case report

    Infective complications following percutaneous renal biopsy are rare, even among immunocompromised. However it is important to be vigilant about such complications, to detect them early and prevent morbidity a...

    Authors: Prashan Buddhika Illeperuma, Harsha Anuruddhika Dissanayake and Eranga Sanjeewa Wijewickrama

    Citation: BMC Nephrology 2018 19:319

    Published on:

  11. Content type: Case report

    Kimura’s disease (KD) is a rare chronic inflammatory disorder with a high incidence of renal involvement. In this report, we present a case study of KD-associated nephrotic syndrome combined with minimal chang...

    Authors: Song Ren, Xin Yi Li, Fang Wang, Ping Zhang, Yuan Zhang, Gui Sen Li, Li Wang and Xiang Zhong

    Citation: BMC Nephrology 2018 19:316

    Published on:

  12. Content type: Case report

    Rapid decline in renal dysfunction due to primary renal lymphoma, or secondary renal lymphoma by infiltration from a primary origin, is extremely rare. There are notably few reports indicating infiltration of ...

    Authors: Ken Matsuda, Hirotaka Fukami, Ayako Saito, Hiroyuki Sato, Satoshi Aoki, Yoichi Takeuchi, Shinji Nakajima and Tasuku Nagasawa

    Citation: BMC Nephrology 2018 19:312

    Published on:

  13. Content type: Case report

    Patients with end-stage kidney disease (ESKD) most commonly complain of gastrointestinal symptoms, such as diarrhea. Diarrhea negatively affects patient quality of life and has miscellaneous etiologies, such as C...

    Authors: Takaaki Higashihara, Akira Okada, Yukiko Kishida, Sayako Maruno, Mimiko Matsumura, Koichi Tamura and Hideki Takano

    Citation: BMC Nephrology 2018 19:303

    Published on:

  14. Content type: Case report

    Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of extranodal diffuse large B-cell lymphoma characterized by proliferation of B cells within small vessels. Herein, we report a case of a 77-year-...

    Authors: Yasuhiro Oda, Kunihiro Ishioka, Takayasu Ohtake, Shuku Sato, Yotaro Tamai, Rikako Oki, Kenji Matsui, Yasuhiro Mochida, Hidekazu Moriya, Sumi Hidaka and Shuzo Kobayashi

    Citation: BMC Nephrology 2018 19:300

    Published on:

  15. Content type: Case report

    Icodextrin is a starch-derived, water soluble glucose polymer, which is used as an alternative to glucose in order to enhance dialytic fluid removal in peritoneal dialysis patients. Although the safety and eff...

    Authors: Vassilios Liakopoulos, Panagiotis I Georgianos, Paraskevi Demirtzi, Vasilios Vaios, Theofanis Kalathas and Pantelis E Zebekakis

    Citation: BMC Nephrology 2018 19:293

    Published on:

  16. Content type: Case report

    Hantavirus infection is an uncommon cause of acute renal failure with massive proteinuria. Serology tests to support a presumptive diagnosis usually take a few days. During the initial work-up, autoimmune caus...

    Authors: H. W. Zijlstra, A. H. L. Mulder, F. Geeraedts and F. Visser

    Citation: BMC Nephrology 2018 19:286

    Published on:

  17. Content type: Case report

    Star fruit is a popular medicinal fruit in the tropics. Its hypoglycaemic properties are considered useful in achieving glycaemic control in diabetes. Star fruit induced nephrotoxicity is a rare cause of acute...

    Authors: Dilushi Rowena Wijayaratne, V. Bavanthan, M. V. C. de Silva, A. L. M. Nazar and Eranga S. Wijewickrama

    Citation: BMC Nephrology 2018 19:288

    Published on:

  18. Content type: Case report

    Lupus nephritis (LN) is a frequent severe complication of Systemic Lupus Erythematosus (SLE), especially in patients of non-Caucasian ethnicity. Induction treatment for LN consists in the combination of steroi...

    Authors: Francesco Fontana, Gaetano Alfano, Marco Leonelli, Caterina Cerami, Giulia Ligabue, Amelia Spinella, Giorgia Citriniti, Carlo Umberto Manzini, Clodoveo Ferri and Gianni Cappelli

    Citation: BMC Nephrology 2018 19:276

    Published on:

  19. Content type: Case report

    Lenvatinib is a tyrosine kinase inhibitor with novel binding ability. It is considered the standard of care for metastatic thyroid cancer; moreover, whether it is indicated for other malignant tumors has been ...

    Authors: Yoshitaka Furuto, Hirotsugu Hashimoto, Akio Namikawa, Haruki Outi, Hiroko Takahashi, Hajime Horiuti, Kazuho Honda and Yuko Shibuya

    Citation: BMC Nephrology 2018 19:273

    Published on:

  20. Content type: Case report

    Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis causes end-stage renal failure in up to a third of cases even with treatment. The disease recurs occasionally after kidney transplantation, but...

    Authors: Michael S. Sagmeister, Max Weiss, Peter Eichhorn, Antje Habicht, Rupert Habersetzer, Michael Fischereder and Ulf Schönermarck

    Citation: BMC Nephrology 2018 19:270

    Published on:

  21. Content type: Case report

    Birt-Hogg-Dubé (BHD) Syndrome is a rare genodermatosis caused by a mutation on folliculin gene, with a strong link to renal cancer. To date few patients with such condition have reached dialysis stage, as neph...

    Authors: Joana Coutinho, Joaquim de Sa, Filipe Castro Teixeira, Catarina Reis Santos, Raquel Sa Chorão, Rui Alves Filipe and Ernesto Fernandes Rocha

    Citation: BMC Nephrology 2018 19:267

    Published on:

  22. Content type: Case report

    Ingestion of vitamin C is generally regarded as harmless. Oxalate nephropathy is an infrequent condition and is characterized by oxalate deposition in the renal tubules, in some cases resulting in acute kidney...

    Authors: Miguel Moyses-Neto, Bruno Rafael Santos Brito, Dyego José de Araújo Brito, Noelia Dias Carneiro Barros, Márcio Dantas, Natalino Salgado-Filho, Roberto Silva Costa and Gyl Eanes Barros Silva

    Citation: BMC Nephrology 2018 19:265

    Published on:

  23. Content type: Case report

    Multicentric Castleman disease (MCD) is an uncommon lymphoproliferative disease characterized by systemic inflammatory reactions associated with the dysregulated production of interleukin-6 (IL-6). In patients...

    Authors: Masatoshi Matsunami, Yoshifumi Ubara, Keiichi Sumida, Yoichi Oshima, Masahiko Oguro, Kazuya Kinoshita, Kiho Tanaka, Yuki Nakamura, Keiichi Kinowaki, Kenichi Ohashi, Takeshi Fujii, Takuro Igawa, Yasuharu Sato and Yasuo Ishii

    Citation: BMC Nephrology 2018 19:263

    Published on:

  24. Content type: Case report

    The development of proteinuria and reduced glomerular filtration rate is associated with higher mortality among patients with sickle cell disease (SCD). AA amyloidosis, also associated with increased mortality...

    Authors: Ann Bugeja, Paula Blanco, Edward G. Clark and Manish M. Sood

    Citation: BMC Nephrology 2018 19:256

    Published on:

  25. Content type: Case report

    The pathophysiologic role of exogenous granulocyte-colony stimulating factor (G-CSF) administration is reportedly linked to the progression of glomerulonephritis. However, the relationship between endogenous G...

    Authors: Seigo Ito, Takahiro Uchida, Naoki Oshima, Takashi Oda and Hiroo Kumagai

    Citation: BMC Nephrology 2018 19:251

    Published on:

  26. Content type: Case report

    The possibility of clearing Cell-free Plasma Hemoglobin (CPH) from human plasma may appear attractive, especially when considering the noxious effects that CPH has on the immune function and the renal damage c...

    Authors: David Cucchiari, Enric Reverter, Miquel Blasco, Alicia Molina-Andujar, Adriá Carpio, Miquel Sanz, Angels Escorsell, Javier Fernández and Esteban Poch

    Citation: BMC Nephrology 2018 19:250

    Published on:

  27. Content type: Case report

    Kidney transplantation is the preferred renal replacement therapy for patients with end-stage renal disease, but the waiting list for kidneys continues to grow because of a shortage of donor organs. The reuse ...

    Authors: Wen-Hsin Tseng, Yu-Feng Tian, Alex Chien-Hwa Liao, Ming-Jenn Chen, Hsuan-Ying Ho, Jinn-Rung Kuo and Steven K. Huang

    Citation: BMC Nephrology 2018 19:234

    Published on:

  28. Content type: Case report

    Anti-glomerular basement membrane (GBM) antibodies are highly specific for Goodpasture’s or anti-GBM disease, in which they are generally directed against the non-collagenous (NC1) domain of the alpha 3 chain ...

    Authors: Omid Sadeghi-Alavijeh, Scott Henderson, Paul Bass, Terence Cook, Kirsten DeGroot and Alan David Salama

    Citation: BMC Nephrology 2018 19:228

    Published on:

  29. Content type: Case report

    Paraneoplastic glomerulonephritis is rare in haematological malignancies and tends to manifest as minimal change disease, membranous glomerulonephritis or membranoproliferative glomerulonephritis. We present t...

    Authors: Monica Suet Ying Ng, Leo Francis, Elango Pillai and Andrew John Mallett

    Citation: BMC Nephrology 2018 19:224

    Published on:

  30. Content type: Case report

    The management of malignancy post kidney transplantation includes reduction in immunosuppression and referral to an oncologist management of their malignancy. Recent advances in oncology have resulted in the a...

    Authors: Jonathan W. Goldman, Basmah Abdalla, Melody A. Mendenhall, Anthony Sisk, Jaime Hunt, Gabriel M. Danovitch and Erik L. Lum

    Citation: BMC Nephrology 2018 19:210

    Published on:

  31. Content type: Case report

    Sixty mutations of claudin 16 coding gene have been reported in familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) patients. Recent investigations revealed that a highly conserved glycine...

    Authors: Jingru Lu, Xiangzhong Zhao, Alessandro Paiardini, Yanhua Lang, Irene Bottillo and Leping Shao

    Citation: BMC Nephrology 2018 19:181

    Published on:

  32. Content type: Case report

    Recurrence of glomerulonephritis is an important risk factor for renal graft dysfunction. Cryoglobulinemia is known as a relatively rare cause of renal failure, and doctors are usually hesitant to perform tran...

    Authors: Tomomichi Kasagi, Hironobu Nobata, Kaori Ikeda, Shogo Banno and Yasuhiko Ito

    Citation: BMC Nephrology 2018 19:170

    Published on:

  33. Content type: Case report

    Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disorder, leading to end stage renal failure and kidney transplantation in its most serious form. The severity of the di...

    Authors: Veronika Elisakova, Miroslav Merta, Jana Reiterova, Alica Baxova, Jaroslav Kotlas, Katerina Hirschfeldova, Lena Obeidova, Vladimir Tesar and Jitka Stekrova

    Citation: BMC Nephrology 2018 19:163

    Published on:

  34. Content type: Case report

    While the majority of adult-onset minimal change nephrotic syndrome (MCNS) is a primary or an idiopathic form of disease, it can also occur as a secondary form. Reports on the spontaneous remission of MCNS are...

    Authors: Ayumi Haruki, Eiji Ishikawa, Kan Katayama, Takayasu Ito, Takuya Hiramoto, Mika Fujimoto, Tomohiro Murata and Masaaki Ito

    Citation: BMC Nephrology 2018 19:162

    Published on:

  35. Content type: Case report

    Gallbladder perforation is a rare but lethal condition and its diagnosis is usually difficult and delayed. Frequently, gallbladder rupture is associated with cholecystitis, but spontaneous perforation was ever...

    Authors: Yueh-Lin Wu, Yi-Sheng Lin, Thomas Yu-Ren Hsueh, Wen-Ching Lo, Kuo-Chou Peng and Mu-Jung Kao

    Citation: BMC Nephrology 2018 19:165

    Published on:

  36. Content type: Case report

    Hypokalemia is one of the most common clinical electrolyte imbalance problems, and thyrotoxic periodic paralysis (TPP) is a leading cause of presentation to the emergency department. Low renal potassium secret...

    Authors: Mei-Lan Tu, Yu-Wei Fang, Jyh-Gang Leu and Ming-Hsien Tsai

    Citation: BMC Nephrology 2018 19:160

    Published on:

  37. Content type: Case report

    Currently, the vasopressin V2 receptor antagonist tolvaptan is the only available treatment for autosomal dominant polycystic kidney disease (ADPKD), but there are tolerability issues due to aquaretic side-eff...

    Authors: Bart J. Kramers, Maatje D. A. van Gastel, Esther Meijer and Ron T. Gansevoort

    Citation: BMC Nephrology 2018 19:157

    Published on:

  38. Content type: Case report

    Peritonitis secondary to bowel perforation is a rare and potentially fatal complication in peritoneal dialysis (PD) patients. However, the early diagnosis of bowel perforation is difficult in PD patients becau...

    Authors: Kentaro Fujii, Naoki Washida, Eri Arai, Masashi Tsuruta, Shu Wakino and Hiroshi Itoh

    Citation: BMC Nephrology 2018 19:153

    Published on:

  39. Content type: Case report

    It has been suggested that C3 glomerulonephritis (C3GN) and atypical hemolytic-uremic syndrome (a stereotypical phenotype of thrombotic microangiopathy), two rare entities caused by complement alternative path...

    Authors: Jiqiu Wen, Wei Wang, Feng Xu, Jun Sun, Jinsong Chen and Xuefeng Ni

    Citation: BMC Nephrology 2018 19:148

    Published on:

  40. Content type: Case report

    Neutrophil extracellular traps (NETs) are web-like DNA decorated with antimicrobial proteins, such as myeloperoxidase (MPO), which are extruded from activated neutrophils. Although NETs are essential in innate...

    Authors: Haruki Shida, Nobuhiro Hashimoto, Yoshihiro Kusunoki, Fumihiko Hattanda, Yayoi Ogawa, Terumasa Hayashi, Daigo Nakazawa, Sakiko Masuda, Utano Tomaru and Akihiro Ishizu

    Citation: BMC Nephrology 2018 19:145

    Published on:

  41. Content type: Case report

    Immunotactoid glomerulopathy (ITG) is a rare glomerulonephritis characterized by microtubular deposits. Immunofluorescence findings are necessary to differentiate ITG from other proliferative glomerular diseas...

    Authors: Shuma Hirashio, Takahiro Arima, Ayaka Satoh, Kouichi Mandai, Shigeo Hara and Takao Masaki

    Citation: BMC Nephrology 2018 19:143

    Published on:

  42. Content type: Case report

    Arthrogryposis-Renal dysfunction-Cholestasis syndrome (ARC, MIM#208085) is a rare multisystem disease due to mutations in the VPS33B and VIPAR genes, both involved in maintaining apical-basolateral cell polarity....

    Authors: Alejandra Rosales, Maissa Mhibik, Paul Gissen, Oscar Segarra, Susana Redecillas and Gema Ariceta

    Citation: BMC Nephrology 2018 19:144

    Published on:

  43. Content type: Case report

    Renal replacement therapy (RRT) with regional citrate anticoagulation (RCA) is an important therapeutic approach for refractory hypercalcemia complicated with renal failure. However, RCA has the potential to i...

    Authors: Buyun Wu, Jing Wang, Guang Yang, Changying Xing and Huijuan Mao

    Citation: BMC Nephrology 2018 19:136

    Published on:

2017 Journal Metrics