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Case Reports

This section welcomes submissions of case reports only.

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  1. Macroscopic hematuria-associated acute kidney injury (AKI) is a well-known complication of immunoglobulin A (IgA) nephropathy. In such cases, intratubular obstruction by red blood cell (RBC) casts and acute tu...

    Authors: Shinya Taguchi, Sumi Hidaka, Mitsuru Yanai, Kunihiro Ishioka, Kenji Matsui, Yasuhiro Mochida, Hidekazu Moriya, Takayasu Ohtake and Shuzo Kobayashi

    Citation: BMC Nephrology 2021 22:132

    Content type: Case report

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  2. Renal tumors during pregnancy are rare and the treatment requires evaluation of both the patient and the fetus. No consensus or guidelines has been proposed or verified in this field. We successfully managed t...

    Authors: Yi Zhao, Ziyi Yang, Weifeng Xu, Zhigang Ji and Jie Dong

    Citation: BMC Nephrology 2021 22:127

    Content type: Case report

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  3. Behçet’s disease (BD) is a systemic inflammatory vasculitis with both autoimmune and autoinflammatory properties. Renal involvement in BD and its spontaneous remission have been rare. We herein describe a case...

    Authors: Kanako Watanabe-Kusunoki, Masaru Kato, Yotaro Oki, Tetsuo Shimizu, Yoshihiro Kusunoki, Shota Furukawa, Shin Furukawa, Hirohiko Kitakawa and Kiyoshi Sakai

    Citation: BMC Nephrology 2021 22:122

    Content type: Case report

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  4. The Japanese chaff flower, Achyranthes japonica, is used as complementary medicine to control degenerative arthritis. Although commonly used in South Korea, there has been no report of side effects. We report the...

    Authors: Ha Nee Jang, Sehyun Jung, Seunghye Lee, Se-Ho Chang, Tae Won Lee, Eunjin Bae and Dong Jun Park

    Citation: BMC Nephrology 2021 22:121

    Content type: Case report

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  5. Plasma cell dyscrasias (PCD) are characterized by an abnormal production of intact monoclonal immunoglobulins or parts such as heavy or light chains. In most cases, the monoclonal protein (also termed paraprot...

    Authors: C. Lindemann, P. Enders, P. T. Brinkkoetter and L. A. Völker

    Citation: BMC Nephrology 2021 22:117

    Content type: Case report

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  6. Primary Sjögren’s syndrome (pSS) is an auto-immune disease characterized by sialadenitis and dacryoadenitis with lymphoplasmacytic cell infiltration. In pSS, not only sicca symptoms, but also extra-glandular i...

    Authors: Ryo Nishioka, Satoshi Hara, Hiroyuki Kawahara, Kiyoaki Ito, Ichiro Mizushima, Masayoshi Hirata, Michio Nagata and Mitsuhiro Kawano

    Citation: BMC Nephrology 2021 22:108

    Content type: Case report

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  7. Inhibition of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) is a novel choice for the treatment of renal anemia, and an oral HIF-PH inhibitor roxadustat was approved for renal anemia. Roxadustat has hig...

    Authors: Mitsuru Ichii, Katsuhito Mori, Daichi Miyaoka, Mika Sonoda, Yoshihiro Tsujimoto, Shinya Nakatani, Tetsuo Shoji and Masanori Emoto

    Citation: BMC Nephrology 2021 22:104

    Content type: Case report

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  8. COVID-19 infection in kidney transplant recipients often lead to allograft dysfunction. The allograft injury has various histopathological manifestations. Our case illustrates the unusual combination of allogr...

    Authors: Urmila Anandh, Swarnalata Gowrishankar, Alok Sharma, Alan Salama and Indranil Dasgupta

    Citation: BMC Nephrology 2021 22:91

    Content type: Case report

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  9. Peritoneal dialysis (PD)-associated peritonitis caused by nontuberculous Mycobacterium is rare; however, the number of cases has increased over the past decades. Mycobacteroides massiliense is a subspecies of the...

    Authors: Shintaro Hamada, Tomoaki Takata, Tsuyoshi Kitaura, Chiori Teraoka, Akio Aono, Sosuke Taniguchi, Yukari Mae, Hajime Isomoto, Hiroki Chikumi and Satoshi Mitarai

    Citation: BMC Nephrology 2021 22:90

    Content type: Case report

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  10. Thrombotic microangiopathy (TMA), a rare but serious complication of systemic lupus erythematosus (SLE), is associated with poor outcomes to conventional immunosuppressive therapy. Recently, eculizumab, a huma...

    Authors: Mi Jung Kim, Haekyung Lee, Yon Hee Kim, So Young Jin, Hee-Jin Kim, Doyeun Oh and Jin Seok Jeon

    Citation: BMC Nephrology 2021 22:86

    Content type: Case report

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  11. Primary hyperoxaluria(PH)is a rare autosomal recessive genetic disease that contains three subtypes (PH1, PH2 and PH3). Approximately 80% of PH patients has been reported as subtype PH1, this subtype of PH has...

    Authors: Chang Bao Xu, Xu Dong Zhou, Hong En Xu, Yong Li Zhao, Xing Hua Zhao, Dan Hua Liu, Yong An Tian, Xin Xin Hu, Jing Yuan Guan, Jian Cheng Guo, Wen Xue Tang and Xia Xue

    Citation: BMC Nephrology 2021 22:83

    Content type: Case report

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  12. Anti-glomerular basement membrane disease (GBM) disease is a rare autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary haemorrhage. Recently, an association between COVID-19 and anti...

    Authors: Alexander Winkler, Emanuel Zitt, Hannelore Sprenger-Mähr, Afschin Soleiman, Manfred Cejna and Karl Lhotta

    Citation: BMC Nephrology 2021 22:75

    Content type: Case report

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  13. Lately, monoclonal gammopathy of renal significance (MGRS) has been defined as a group of renal disorders that are strongly associated with monoclonal protein, including amyloid immunoglobulin light chain (AL)...

    Authors: Erina Ono, Akira Ishii, Yoshiaki Higashi, Natsuko Koita, Takashi Ayaki, Katsuya Tanigaki, Shunsuke Takayanagi, Naoya Kondo, Kaoru Sakai, Shuichiro Endo, Hideki Yokoi, Takeshi Matsubara, Sachiko Minamiguchi, Ichizo Nishino, Ryosuke Takahashi and Motoko Yanagita

    Citation: BMC Nephrology 2021 22:74

    Content type: Case report

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  14. The association of hypertension with congenital renal hypoplasia has been established. We report a case of an infant who underwent nephrectomy for hypertension.

    Authors: Keisuke Sugimoto, Takuji Enya, Kensuke Joh, Kohei Miyazaki, Tomoki Miyazawa, Rina Ohshima, Satoshi Marutani, Takemura Tsukasa and Mitsuru Okada

    Citation: BMC Nephrology 2021 22:55

    Content type: Case report

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  15. Anti-glomerular basement membrane (anti-GBM) disease is an organ-specific autoimmune disease that involves the lung and kidneys and leads to rapid glomerulonephritis progression, with or without diffuse alveol...

    Authors: Na Guo, Qinghua Yin, Song Lei, Yanjun He and Ping Fu

    Citation: BMC Nephrology 2021 22:53

    Content type: Case report

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  16. Heterozygous mutations in the inverted formin 2 (INF2) gene are related to secondary focal segmental glomerulosclerosis (FSGS), a rare secondary disease associated with rapidly progressive renal failure.

    Authors: Wenbo Zhao, Xinxin Ma, Xiaohao Zhang, Dan Luo, Jun Zhang, Ming Li, Zengchun Ye and Hui Peng

    Citation: BMC Nephrology 2021 22:51

    Content type: Case report

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  17. Ankylosing spondylitis (AS) is an insidiously progressive and debilitating form of arthritis involving the axial skeleton, characterized by chronic back pain and progressive spinal stiffness, and lessening of ...

    Authors: Anna Zawiasa-Bryszewska, Olga Brzezińska, Ilona Kurnatowska and Joanna Makowska

    Citation: BMC Nephrology 2021 22:46

    Content type: Case report

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    The Correction to this article has been published in BMC Nephrology 2021 22:78

  18. Light chain cast nephropathy (LCCN) is the most common renal disease caused by multiple myeloma (MM). In addition to ordinary light chain protein casts, there are a few rare casts with unique shapes, including...

    Authors: Li-Jun Sun, Hong-Rui Dong, Xiao-Yi Xu, Guo-Qin Wang, Hong Cheng and Yi-Pu Chen

    Citation: BMC Nephrology 2021 22:42

    Content type: Case report

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  19. IgD multiple myeloma (MM) is a rare subtype of MM and light chain deposition disease (LCDD) outside the kidney is also a rare and has scarcely been reported. We report herein the details of the first reported ...

    Authors: Takafumi Tsushima, Tomo Suzuki, Toshiki Terao, Daisuke Miura, Kentaro Narita, Masami Takeuchi, Akira Shimuzu and Kosei Matsue

    Citation: BMC Nephrology 2021 22:40

    Content type: Case report

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  20. IgG4-related kidney disease causes renal impairment of unknown pathogenesis that may progress to kidney failure. Although ectopic germinal centers contribute to the pathogenesis of the head and neck lesions of...

    Authors: Tatsuhito Miyanaga, Keishi Mizuguchi, Satoshi Hara, Takeshi Zoshima, Dai Inoue, Ryo Nishioka, Ichiro Mizushima, Kiyoaki Ito, Hiroshi Fuji, Kazunori Yamada, Yuki Sato, Motoko Yanagita and Mitsuhiro Kawano

    Citation: BMC Nephrology 2021 22:34

    Content type: Case report

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  21. Treatment with proteasome inhibitors like carfilzomib in patients with multiple myeloma (MM) can induce thrombotic microangiopathy (TMA) characterized by neurological symptoms, acute kidney injury, hemolysis a...

    Authors: Michael Rassner, Rebecca Baur, Ralph Wäsch, Mario Schiffer, Johanna Schneider, Andreas Mackensen and Monika Engelhardt

    Citation: BMC Nephrology 2021 22:32

    Content type: Case report

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  22. Dent disease is an X-linked form of progressive renal disease. This rare disorder was characterized by hypercalciuria, low molecular weight (LMW) proteinuria and proximal tubular dysfunction, caused by pathoge...

    Authors: Nan Duan, Chenwei Huang, Lu Pang, Shiju Jiang, Wenshuang Yang and Haixia Li

    Citation: BMC Nephrology 2021 22:24

    Content type: Case report

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  23. IgG4-related kidney disease (IgG4-RKD) can affect multiple organs, which was first reported as a complication or extra-organ manifestation of autoimmune pancreatitis in 2004. It is characterized by abundant Ig...

    Authors: Yili Xu, Guang Yang, Xueqiang Xu, Yaoyu Huang, Kang Liu, Tongfu Yu, Jun Qian, Xiufen Zhao, Jingfeng Zhu, Ningning Wang and Changying Xing

    Citation: BMC Nephrology 2021 22:22

    Content type: Case report

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  24. Acute kidney injury (AKI) associated with severe coronavirus disease 19 (COVID-19) is common and is a significant predictor of morbidity and mortality, especially when dialysis is required. Case reports and au...

    Authors: Katarzyna Szajek, Marie-Elisabeth Kajdi, Valerie A. Luyckx, Thomas Hans Fehr, Ariana Gaspert, Alexia Cusini, Karin Hohloch and Philipp Grosse

    Citation: BMC Nephrology 2021 22:19

    Content type: Case report

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  25. Some sea anemone toxins cause renal injuries resembling hemolytic uremic syndrome (HUS). To date, only a few cases of HUS caused by sea anemone stings have been reported. In this case report, we have described...

    Authors: A Young Kim, Kyu Hyang Cho, Seok Hui Kang, Jong Won Park, Jun Young Do and Min Kyoung Kim

    Citation: BMC Nephrology 2021 22:14

    Content type: Case report

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  26. AarF domain-containing kinase 4 (ADCK4)-associated glomerulopathy is a mitochondrial nephropathy caused by mutations in the ADCK4 gene, which disrupt coenzyme Q10 biosynthesis.

    Authors: Yan Zhang, Xiaohua Liao, Yupeng Jiang, Xin Lv, Yue Yu, Qin Dai, Liyun Ao, Lijian Tao and Zhangzhe Peng

    Citation: BMC Nephrology 2021 22:11

    Content type: Case report

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  27. Multiple myeloma (MM) is a plasma-cell derived hematologic malignant disease. The malignant proliferating plasma cells secrete massive monoclonal immunoglobulins which lead to various pathologic types of renal...

    Authors: Zi-hao Yong, Xiao-juan Yu, Zi-shan Lin, Fu-de Zhou, Xi-nan Cen, Su-xia Wang and Ming-hui Zhao

    Citation: BMC Nephrology 2021 22:6

    Content type: Case report

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  28. An arteriovenous fistula (AVF) is the first choice when considering access for haemodialysis (HD). When a forearm AVF fails an upper arm AVF is a frequent subsequent dialysis access option. The latter may caus...

    Authors: Michaela Wärja, Emelie Laveborn, Michael Ott, Andreas P. Jonsson and Bernd Stegmayr

    Citation: BMC Nephrology 2020 21:544

    Content type: Case report

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  29. Idiopathic multicentric Castleman disease (iMCD) is an uncommon lymphoproliferative disorder and lacks treatment consensus. Herein, we report a case of iMCD complicated with Sjögren’s syndrome (SS) and seconda...

    Authors: Yuejuan Pan, Zhuan Cui, Song Wang, Danxia Zheng, Zhenling Deng, Xinyu Tian, Hongxia Guo, Wenhan Bao, Sijia Zhou and Yue Wang

    Citation: BMC Nephrology 2020 21:528

    Content type: Case report

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  30. Tunneled catheters can be used as an alternative vascular access in patients with limited health expectancy,vascular access problems and several comorbidities. We aimed to present a patient with venous stenosi...

    Authors: Sumeyra Koyuncu, Nevzat Herdem, Cihan Uysal, Guven Kahriman, Ismail Kocyigit, Murat Sipahioğlu, Bulent Tokgoz and Oktay Oymak

    Citation: BMC Nephrology 2020 21:525

    Content type: Case report

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  31. Reduction in bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) occurs in secondary hyperparathyroidism associated with chronic kidney disease. BMD generally increases following para...

    Authors: Raymond Lin, Mirna Vucak-Dzumhur and Grahame J. Elder

    Citation: BMC Nephrology 2020 21:513

    Content type: Case report

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  32. Since the Coronavirus Disease 2019 (COVID-19) outbreak, there is accumulating data on the clinical characteristics, treatment strategies and prognosis of COVID-19 in patients with concurrent renal disease. Pos...

    Authors: Yi Huang, Xiao-Juan Li, Yue-Qiang Li, Wei Dai, Tiffany Shao, Wei-Yong Liu, Min Han, Gang Xu and Liu Liu

    Citation: BMC Nephrology 2020 21:504

    Content type: Case report

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  33. TAFRO syndrome is a clinical subtype of idiopathic multicentric Castleman disease (iMCD) that is characterized by thrombocytopenia, anasarca, fever, reticulin myelofibrosis (or renal dysfunction), and organome...

    Authors: Qianyun Zhou, Yuanyuan Zhang, Guangping Zhou and Jihong Zhu

    Citation: BMC Nephrology 2020 21:499

    Content type: Case report

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  34. Glomerular involvement in rheumatoid arthritis has been known to be associated with treatment side effects from medications and secondary amyloidosis. However, limited basic science and clinical studies have b...

    Authors: Qiyu Wang, Juan P. Ruiz and Peter D. Hart

    Citation: BMC Nephrology 2020 21:496

    Content type: Case report

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  35. Peritoneal dialysis (PD) is a form of therapy for end-stage kidney disease (ESKD), and peritonitis is a known complication. Mycobacterium (M) species associated peritonitis in PD patients is uncommon. Our experie...

    Authors: Anup Singh Jheeta, Jayakeerthi Rangaiah, John Clark, David Makanjuola and Subash Somalanka

    Citation: BMC Nephrology 2020 21:491

    Content type: Case report

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  36. In patients with frequently relapsing nephrotic syndrome, immunosuppressive therapy such as cyclosporine are often required to maintain remission. Cyclosporine has been noted to have tumorgenesis effects. In t...

    Authors: Huai-Chueh Gem Wu, Chao-Neng Cheng, Jiann-Shiuh Chen and Yuan-Yow Chiou

    Citation: BMC Nephrology 2020 21:490

    Content type: Case report

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  37. Pregnancy-related Atypical Haemolytic Uremic Syndrome (P-aHUS) is a rare condition affecting genetically predisposed women during pregnancy. It is often difficult to diagnose and has a significant impact on ma...

    Authors: Prianka Puri, Anida Hanxhiu, Daniel V. O’Hara, Danny Hsu and Mirna Vucak-Dzumhur

    Citation: BMC Nephrology 2020 21:488

    Content type: Case report

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  38. Peritoneal dialysis-associated peritonitis can uncommonly be caused by fungal infections. When they do present, they are associated with significant mortality and morbidity. We describe a case where a sample o...

    Authors: Victoria Jane Carnall, Stephanie Murdock, Cressida Auckland and Christopher J. Mulgrew

    Citation: BMC Nephrology 2020 21:474

    Content type: Case report

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  39. Angioimmunoblastic T cell lymphoma (AITL) is an infrequent hematological malignancy with variable and often atypical presentations. The presence of dysproteinemia, autoantibodies and systemic involvement in AI...

    Authors: Xiang-Yang Li, Hai-Yan He, Shu-Ling Yue and Pearl Pai

    Citation: BMC Nephrology 2020 21:463

    Content type: Case report

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  40. Most patients with cystic fibrosis (CF) present with respiratory or digestive symptoms. About 3% of patients have electrolyte disturbances at the time of diagnosis, but most of the described cases presenting w...

    Authors: Yangming Cao, Rachel Donaldson and David Lee

    Citation: BMC Nephrology 2020 21:462

    Content type: Case report

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  41. Renal angiomyolipoma (RAML) is a rare benign kidney tumour comprised of adipose tissue, smooth muscle, and blood vessels. It can cause fatal complications if it ruptures. Although there have been reports of RA...

    Authors: Zechuan Liu, Yinghua Zou, Tianshi Lv, Haitao Guan and Zeyang Fan

    Citation: BMC Nephrology 2020 21:455

    Content type: Case report

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  42. Transplant renal artery stenosis (TRAS) is a serious vascular complication that occurs after renal transplantation and can result in hypertension, renal functional impairment, and graft loss. Endovascular trea...

    Authors: Xiangjun Dong, Yingliang Wang, Huimin Liang, Chuansheng Zheng, Hui Zhao, Hong yao Hu, Xi Long and Yangbo Su

    Citation: BMC Nephrology 2020 21:439

    Content type: Case report

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  43. Guillain-Barré syndrome (GBS) is an autoimmune polyneuropathy affecting the peripheral nervous system. This neurological disorder has been previously reported in bone marrow transplant recipients but is uncomm...

    Authors: Izabela Zakrocka, Iwona Baranowicz-Gąszczyk, Agnieszka Korolczuk and Wojciech Załuska

    Citation: BMC Nephrology 2020 21:434

    Content type: Case report

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  44. Idiopathic membranous nephropathy (MN) is one of the major glomerulonephritis that cause nephrotic syndrome. The phospholipase A2 receptor (PLA2R) has recently been identified as an endogenous antigen of idiopath...

    Authors: Rei Iio, Shin’ichi Akiyama, Kensuke Mitsumoto, Yukimasa Iwata, Hiroki Okushima, Karin Shimada, Naomi Ota, Kodo Tomida, Hiroaki Fushimi, Tatsuya Shoji, Masanori Matsumoto and Terumasa Hayashi

    Citation: BMC Nephrology 2020 21:431

    Content type: Case report

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  45. Minimal change disease (MCD) is one of the causes of idiopathic nephrotic syndrome in adults. The pathogenesis of proteinuria in MCD has not been fully understood. Recently, it has been reported that the recep...

    Authors: Keisuke Horikoshi, Norihiko Sakai, Naoki Yamamoto, Hisayuki Ogura, Koichi Sato, Taro Miyagawa, Shinji Kitajima, Tadashi Toyama, Akinori Hara, Yasunori Iwata, Miho Shimizu, Kengo Furuichi and Takashi Wada

    Citation: BMC Nephrology 2020 21:416

    Content type: Case report

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  46. Concurrent type 1 diabetes mellitus (T1DM) and idiopathic nephrotic syndrome is rare, and most previously reported cases were in children. We report the case of an adult woman who developed T1DM and minimal ch...

    Authors: Ryuzoh Nishizono, Hiroki Kogou, Yuri Ishizaki, Akihiro Minakawa, Masao Kikuchi, Hiroko Inagaki, Yuji Sato and Shouichi Fujimoto

    Citation: BMC Nephrology 2020 21:410

    Content type: Case report

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  47. Herein, a 3-year-old boy presented with hidden-onset isolated proteinuria was reported. The disease was induced by COQ8B (previously termed ADCK4) compound heterozygous variants, including c.[271C > T] and c.[737...

    Authors: Shu-bo Zhai, Li Zhang, Bai-chao Sun, Yan Zhang and Qing-shan Ma

    Citation: BMC Nephrology 2020 21:406

    Content type: Case report

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  48. We here report on the first observation of a C3 mutation that is related to atypical hemolytic and uremic syndrome (aHUS), which occurred in a pancreatic islet transplant patient. Immunosuppressive treatments,...

    Authors: Thibault Bahougne, Jérome Olagne, Marion Munch, Laura Braun-Parvez, Marie-Pierrette Chenard, Véronique Frémeaux-Bacchi, Sophie Caillard, Philippe Baltzinger, Michel Greget, Laurence Kessler and Bruno Moulin

    Citation: BMC Nephrology 2020 21:405

    Content type: Case report

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