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Case Reports

This section welcomes submissions of case reports only.

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  1. Lupus nephritis (LN) is a frequent severe complication of Systemic Lupus Erythematosus (SLE), especially in patients of non-Caucasian ethnicity. Induction treatment for LN consists in the combination of steroi...

    Authors: Francesco Fontana, Gaetano Alfano, Marco Leonelli, Caterina Cerami, Giulia Ligabue, Amelia Spinella, Giorgia Citriniti, Carlo Umberto Manzini, Clodoveo Ferri and Gianni Cappelli

    Citation: BMC Nephrology 2018 19:276

    Content type: Case report

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  2. Lenvatinib is a tyrosine kinase inhibitor with novel binding ability. It is considered the standard of care for metastatic thyroid cancer; moreover, whether it is indicated for other malignant tumors has been ...

    Authors: Yoshitaka Furuto, Hirotsugu Hashimoto, Akio Namikawa, Haruki Outi, Hiroko Takahashi, Hajime Horiuti, Kazuho Honda and Yuko Shibuya

    Citation: BMC Nephrology 2018 19:273

    Content type: Case report

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  3. Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis causes end-stage renal failure in up to a third of cases even with treatment. The disease recurs occasionally after kidney transplantation, but...

    Authors: Michael S. Sagmeister, Max Weiss, Peter Eichhorn, Antje Habicht, Rupert Habersetzer, Michael Fischereder and Ulf Schönermarck

    Citation: BMC Nephrology 2018 19:270

    Content type: Case report

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  4. Birt-Hogg-Dubé (BHD) Syndrome is a rare genodermatosis caused by a mutation on folliculin gene, with a strong link to renal cancer. To date few patients with such condition have reached dialysis stage, as neph...

    Authors: Joana Coutinho, Joaquim de Sa, Filipe Castro Teixeira, Catarina Reis Santos, Raquel Sa Chorão, Rui Alves Filipe and Ernesto Fernandes Rocha

    Citation: BMC Nephrology 2018 19:267

    Content type: Case report

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  5. Ingestion of vitamin C is generally regarded as harmless. Oxalate nephropathy is an infrequent condition and is characterized by oxalate deposition in the renal tubules, in some cases resulting in acute kidney...

    Authors: Miguel Moyses-Neto, Bruno Rafael Santos Brito, Dyego José de Araújo Brito, Noelia Dias Carneiro Barros, Márcio Dantas, Natalino Salgado-Filho, Roberto Silva Costa and Gyl Eanes Barros Silva

    Citation: BMC Nephrology 2018 19:265

    Content type: Case report

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  6. Multicentric Castleman disease (MCD) is an uncommon lymphoproliferative disease characterized by systemic inflammatory reactions associated with the dysregulated production of interleukin-6 (IL-6). In patients...

    Authors: Masatoshi Matsunami, Yoshifumi Ubara, Keiichi Sumida, Yoichi Oshima, Masahiko Oguro, Kazuya Kinoshita, Kiho Tanaka, Yuki Nakamura, Keiichi Kinowaki, Kenichi Ohashi, Takeshi Fujii, Takuro Igawa, Yasuharu Sato and Yasuo Ishii

    Citation: BMC Nephrology 2018 19:263

    Content type: Case report

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  7. The development of proteinuria and reduced glomerular filtration rate is associated with higher mortality among patients with sickle cell disease (SCD). AA amyloidosis, also associated with increased mortality...

    Authors: Ann Bugeja, Paula Blanco, Edward G. Clark and Manish M. Sood

    Citation: BMC Nephrology 2018 19:256

    Content type: Case report

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  8. The pathophysiologic role of exogenous granulocyte-colony stimulating factor (G-CSF) administration is reportedly linked to the progression of glomerulonephritis. However, the relationship between endogenous G...

    Authors: Seigo Ito, Takahiro Uchida, Naoki Oshima, Takashi Oda and Hiroo Kumagai

    Citation: BMC Nephrology 2018 19:251

    Content type: Case report

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  9. The possibility of clearing Cell-free Plasma Hemoglobin (CPH) from human plasma may appear attractive, especially when considering the noxious effects that CPH has on the immune function and the renal damage c...

    Authors: David Cucchiari, Enric Reverter, Miquel Blasco, Alicia Molina-Andujar, Adriá Carpio, Miquel Sanz, Angels Escorsell, Javier Fernández and Esteban Poch

    Citation: BMC Nephrology 2018 19:250

    Content type: Case report

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  10. Kidney transplantation is the preferred renal replacement therapy for patients with end-stage renal disease, but the waiting list for kidneys continues to grow because of a shortage of donor organs. The reuse ...

    Authors: Wen-Hsin Tseng, Yu-Feng Tian, Alex Chien-Hwa Liao, Ming-Jenn Chen, Hsuan-Ying Ho, Jinn-Rung Kuo and Steven K. Huang

    Citation: BMC Nephrology 2018 19:234

    Content type: Case report

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  11. Anti-glomerular basement membrane (GBM) antibodies are highly specific for Goodpasture’s or anti-GBM disease, in which they are generally directed against the non-collagenous (NC1) domain of the alpha 3 chain ...

    Authors: Omid Sadeghi-Alavijeh, Scott Henderson, Paul Bass, Terence Cook, Kirsten DeGroot and Alan David Salama

    Citation: BMC Nephrology 2018 19:228

    Content type: Case report

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  12. Paraneoplastic glomerulonephritis is rare in haematological malignancies and tends to manifest as minimal change disease, membranous glomerulonephritis or membranoproliferative glomerulonephritis. We present t...

    Authors: Monica Suet Ying Ng, Leo Francis, Elango Pillai and Andrew John Mallett

    Citation: BMC Nephrology 2018 19:224

    Content type: Case report

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  13. The management of malignancy post kidney transplantation includes reduction in immunosuppression and referral to an oncologist management of their malignancy. Recent advances in oncology have resulted in the a...

    Authors: Jonathan W. Goldman, Basmah Abdalla, Melody A. Mendenhall, Anthony Sisk, Jaime Hunt, Gabriel M. Danovitch and Erik L. Lum

    Citation: BMC Nephrology 2018 19:210

    Content type: Case report

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  14. Sixty mutations of claudin 16 coding gene have been reported in familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) patients. Recent investigations revealed that a highly conserved glycine...

    Authors: Jingru Lu, Xiangzhong Zhao, Alessandro Paiardini, Yanhua Lang, Irene Bottillo and Leping Shao

    Citation: BMC Nephrology 2018 19:181

    Content type: Case report

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  15. Recurrence of glomerulonephritis is an important risk factor for renal graft dysfunction. Cryoglobulinemia is known as a relatively rare cause of renal failure, and doctors are usually hesitant to perform tran...

    Authors: Tomomichi Kasagi, Hironobu Nobata, Kaori Ikeda, Shogo Banno and Yasuhiko Ito

    Citation: BMC Nephrology 2018 19:170

    Content type: Case report

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  16. Gallbladder perforation is a rare but lethal condition and its diagnosis is usually difficult and delayed. Frequently, gallbladder rupture is associated with cholecystitis, but spontaneous perforation was ever...

    Authors: Yueh-Lin Wu, Yi-Sheng Lin, Thomas Yu-Ren Hsueh, Wen-Ching Lo, Kuo-Chou Peng and Mu-Jung Kao

    Citation: BMC Nephrology 2018 19:165

    Content type: Case report

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  17. Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disorder, leading to end stage renal failure and kidney transplantation in its most serious form. The severity of the di...

    Authors: Veronika Elisakova, Miroslav Merta, Jana Reiterova, Alica Baxova, Jaroslav Kotlas, Katerina Hirschfeldova, Lena Obeidova, Vladimir Tesar and Jitka Stekrova

    Citation: BMC Nephrology 2018 19:163

    Content type: Case report

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  18. While the majority of adult-onset minimal change nephrotic syndrome (MCNS) is a primary or an idiopathic form of disease, it can also occur as a secondary form. Reports on the spontaneous remission of MCNS are...

    Authors: Ayumi Haruki, Eiji Ishikawa, Kan Katayama, Takayasu Ito, Takuya Hiramoto, Mika Fujimoto, Tomohiro Murata and Masaaki Ito

    Citation: BMC Nephrology 2018 19:162

    Content type: Case report

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  19. Hypokalemia is one of the most common clinical electrolyte imbalance problems, and thyrotoxic periodic paralysis (TPP) is a leading cause of presentation to the emergency department. Low renal potassium secret...

    Authors: Mei-Lan Tu, Yu-Wei Fang, Jyh-Gang Leu and Ming-Hsien Tsai

    Citation: BMC Nephrology 2018 19:160

    Content type: Case report

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  20. Currently, the vasopressin V2 receptor antagonist tolvaptan is the only available treatment for autosomal dominant polycystic kidney disease (ADPKD), but there are tolerability issues due to aquaretic side-eff...

    Authors: Bart J. Kramers, Maatje D. A. van Gastel, Esther Meijer and Ron T. Gansevoort

    Citation: BMC Nephrology 2018 19:157

    Content type: Case report

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  21. Peritonitis secondary to bowel perforation is a rare and potentially fatal complication in peritoneal dialysis (PD) patients. However, the early diagnosis of bowel perforation is difficult in PD patients becau...

    Authors: Kentaro Fujii, Naoki Washida, Eri Arai, Masashi Tsuruta, Shu Wakino and Hiroshi Itoh

    Citation: BMC Nephrology 2018 19:153

    Content type: Case report

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  22. It has been suggested that C3 glomerulonephritis (C3GN) and atypical hemolytic-uremic syndrome (a stereotypical phenotype of thrombotic microangiopathy), two rare entities caused by complement alternative path...

    Authors: Jiqiu Wen, Wei Wang, Feng Xu, Jun Sun, Jinsong Chen and Xuefeng Ni

    Citation: BMC Nephrology 2018 19:148

    Content type: Case report

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  23. Neutrophil extracellular traps (NETs) are web-like DNA decorated with antimicrobial proteins, such as myeloperoxidase (MPO), which are extruded from activated neutrophils. Although NETs are essential in innate...

    Authors: Haruki Shida, Nobuhiro Hashimoto, Yoshihiro Kusunoki, Fumihiko Hattanda, Yayoi Ogawa, Terumasa Hayashi, Daigo Nakazawa, Sakiko Masuda, Utano Tomaru and Akihiro Ishizu

    Citation: BMC Nephrology 2018 19:145

    Content type: Case report

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  24. Arthrogryposis-Renal dysfunction-Cholestasis syndrome (ARC, MIM#208085) is a rare multisystem disease due to mutations in the VPS33B and VIPAR genes, both involved in maintaining apical-basolateral cell polarity....

    Authors: Alejandra Rosales, Maissa Mhibik, Paul Gissen, Oscar Segarra, Susana Redecillas and Gema Ariceta

    Citation: BMC Nephrology 2018 19:144

    Content type: Case report

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  25. Immunotactoid glomerulopathy (ITG) is a rare glomerulonephritis characterized by microtubular deposits. Immunofluorescence findings are necessary to differentiate ITG from other proliferative glomerular diseas...

    Authors: Shuma Hirashio, Takahiro Arima, Ayaka Satoh, Kouichi Mandai, Shigeo Hara and Takao Masaki

    Citation: BMC Nephrology 2018 19:143

    Content type: Case report

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  26. Renal replacement therapy (RRT) with regional citrate anticoagulation (RCA) is an important therapeutic approach for refractory hypercalcemia complicated with renal failure. However, RCA has the potential to i...

    Authors: Buyun Wu, Jing Wang, Guang Yang, Changying Xing and Huijuan Mao

    Citation: BMC Nephrology 2018 19:136

    Content type: Case report

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  27. Sickle cell trait is not completely benign, and some renal complications can occur. The baseline rate of admission for gross hematuria in normal males carrying the sickle cell trait is 2%.

    Authors: Alexandre Le Joncour, Laurent Mesnard, Alexandre Hertig and Thomas Robert

    Citation: BMC Nephrology 2018 19:133

    Content type: Case report

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  28. Catastrophic antiphospholipid syndrome (CAPS) is a rare, life-threatening form of antiphospholipid syndrome (APS) involving many organs and leading to their insufficiency. The pathogenesis of CAPS is associate...

    Authors: Aleksandra Rymarz and Stanisław Niemczyk

    Citation: BMC Nephrology 2018 19:132

    Content type: Case report

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  29. Morbidity associated with monoclonal gammopathy of renal significance is high due to the severe renal lesions and the associated systemic alterations. Accordingly, early diagnosis is fundamental, as is stoppin...

    Authors: Juana Alonso-Titos, Lara Perea-Ortega, Eugenia Sola, Alvaro Torres-Rueda, Myriam León, Remedios Toledo, Ana D. Duarte, Teresa Vazquez, Maria Dolores Martinez-Esteban, Alicia Bailen, Pedro Ruiz-Esteban and Domingo Hernandez

    Citation: BMC Nephrology 2018 19:129

    Content type: Case report

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  30. Epithelioid angiomyolipoma is defined as potentially malignant mesenchymal neoplasm, characterized by proliferating epithelioid cells, whereas classic angiomyolipoma, composed of fat, smooth muscle cells and d...

    Authors: Jan Tuma, Holger Moch, Gerd Stuckmann, Walter Gysel and Andreas L. Serra

    Citation: BMC Nephrology 2018 19:123

    Content type: Case report

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  31. Liddle’s syndrome is a rare monogenic form of hypertension caused by truncating or missense mutations in the C termini of the epithelial sodium channel (ENaC) β or γ subunits. Patients with this syndrome prese...

    Authors: Eriko Yamaguchi, Kazuhiro Yoshikawa, Izaya Nakaya, Karen Kato, Yoshikazu Miyasato, Terumasa Nakagawa, Yutaka Kakizoe, Masashi Mukoyama and Jun Soma

    Citation: BMC Nephrology 2018 19:122

    Content type: Case report

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  32. Podocyte phospholipase A2 receptor (PLA2R) is a major target antigen in idiopathic adult membranous nephropathy (MN). Histological PLA2R staining in the renal tissue has proven to be useful for the detection of i...

    Authors: Kenta Tominaga, Takahiro Uchida, Toshihiko Imakiire, Kenji Itoh, Hideyuki Shimazaki, Kuniaki Nakanishi, Hiroo Kumagai and Naoki Oshima

    Citation: BMC Nephrology 2018 19:120

    Content type: Case report

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  33. Although the relationship between hyperparathyroidism and hypertension has been described for decades, the role of hyperparathyroidism in hypertension in dialysis is still unclear. Following the case of a seve...

    Authors: Andreea Corina Sofronie, Isabelle Kooij, Claude Bursot, Giulia Santagati, Jean-Philippe Coindre and Giorgina Barbara Piccoli

    Citation: BMC Nephrology 2018 19:112

    Content type: Case report

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  34. Lipodystrophy syndromes are rare disorders of variable body fat loss associated with potentially serious metabolic complications. Familial partial lipodystrophy (FPLD) is mostly inherited as an autosomal domin...

    Authors: Ru-Xuan Chen, Lei Zhang, Wei Ye, Yu-Bing Wen, Nuo Si, Hang Li, Ming-Xi Li, Xue-Mei Li and Ke Zheng

    Citation: BMC Nephrology 2018 19:111

    Content type: Case report

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  35. Complement component 3 (C3) glomerulopathy, which includes dense deposit disease (DDD) and C3 glomerulonephritis, is caused by dysregulation of the alternative complement pathway. In most cases, C3 glomerulopa...

    Authors: Shuma Hirashio, Ayaka Satoh, Takahiro Arima, Kouichi Mandai, Tadasuke Awaya, Kumi Oshima, Shigeo Hara and Takao Masaki

    Citation: BMC Nephrology 2018 19:108

    Content type: Case report

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  36. Monoclonal gammopathy causes several kinds of renal pathology. A rare and special form is monoclonal gammopathy-induced C3 glomerulopathy (MG-C3G). Like idiopathic C3G, MG-C3G frequently leads to end-stage ren...

    Authors: Philipp Moog, Philipp J. Jost and Maike Büttner-Herold

    Citation: BMC Nephrology 2018 19:106

    Content type: Case report

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  37. Urinothorax is defined as the presence of urine in the pleural space and is a rather rare cause of transudate pleural effusion. The potential etiologies are urinary tract obstruction and trauma. Diagnosis requ...

    Authors: Tae Won Lee, Ha Nee Jang, Hyun Seop Cho, See Min Choi, Bong-Hoi Choi, Eunjin Bae, Se-Ho Chang and Dong Jun Park

    Citation: BMC Nephrology 2018 19:104

    Content type: Case report

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  38. Cryptococcosis is an important opportunistic infection of organ transplant recipients. It is the third most common fungal infection of transplant patients and occurs especially in kidney recipients. Cryptococcus ...

    Authors: Albert Z. Muranda, Ludolf Greeff, Mike M. Sathekge, Thabo Lengano and Victor O. L. Karusseit

    Citation: BMC Nephrology 2018 19:94

    Content type: Case report

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  39. The poorly differentiated renal cell carcinoma (RCC) with rhabdomyosarcomatous sarcomatoid differentiation shows a severely aggressive biological behavior characterized by rapid disease progression. Preoperati...

    Authors: Xiang Liang, Yupin Liu, Pengcheng Ran, Meili Tang, Changlei Xu and Yazhen Zhu

    Citation: BMC Nephrology 2018 19:84

    Content type: Case report

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  40. C3 glomerulonephritis is a rare glomerulopathy characterized at renal biopsy by C3 deposition, alone or with scanty immunoglobulins, as well as by an electron-dense material in mesangium, subendothelial and su...

    Authors: Domenico Santoro, Rossella Siligato, Carmela Vadalà, Mariacristina Lucanto, Simona Cristadoro, Giovanni Conti, Michele Buemi, Stefano Costa, Ettore Sabadini and Giuseppe Magazzù

    Citation: BMC Nephrology 2018 19:73

    Content type: Case report

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  41. Vancomycin is the first-line antibiotic for methicillin-resistant Staphylococcus aureus and coagulase-negative strains. The risk of vancomycin-induced acute kidney injury increases with plasma vancomycin levels. ...

    Authors: Anri Sawada, Kunio Kawanishi, Shohei Morikawa, Toshihiro Nakano, Mio Kodama, Mitihiro Mitobe, Sekiko Taneda, Junki Koike, Mamiko Ohara, Yoji Nagashima, Kosaku Nitta and Takahiro Mochizuki

    Citation: BMC Nephrology 2018 19:72

    Content type: Case report

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  42. Immune thrombocytopenic purpura (ITP) is primarily characterized by immune-mediated destruction of platelets in circulation. Major treatment options range from careful observation, steroids, immunosuppressive ...

    Authors: Raja Muhammad Rashid, Zahid Nabi, Ahmad Zaki Ansari and Quratul-ain Qaiser

    Citation: BMC Nephrology 2018 19:69

    Content type: Case report

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  43. Both prevention and treatment of recurrent immunoglobulin A nephropathy (IgAN) in kidney transplant recipients are important since recurrent IgAN seems to affect long-term graft survival. We present here a cas...

    Authors: Haruki Katsumata, Izumi Yamamoto, Yo Komatsuzaki, Mayuko Kawabe, Yusuke Okabayashi, Takafumi Yamakawa, Ai Katsuma, Yasuyuki Nakada, Akimitsu Kobayashi, Yudo Tanno, Jun Miki, Hiroki Yamada, Ichiro Ohkido, Nobuo Tsuboi, Hiroyasu Yamamoto and Takashi Yokoo

    Citation: BMC Nephrology 2018 19:64

    Content type: Case report

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