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Clinical Research

The Clinical Research section considers both interventional and non-interventional clinical research studies, including, but not limited to, controlled trials and case-control studies. This section does not consider basic experimental research, large epidemiological studies, or case reports. Systematic reviews, meta-analyses and epidemiological studies should be directed to the Epidemiology and Health Outcomes section, and case reports should be directed to our dedicated Case Reports section. 

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  1. We established earlier the absolute renal risk (ARR) of dialysis/death (D/D) in primary IgA nephropathy (IgAN) which permitted accurate prospective prediction of final prognosis. This ARR was based on the pote...

    Authors: Hesham Mohey, Blandine Laurent, Christophe Mariat and Francois Berthoux

    Citation: BMC Nephrology 2013 14:169

    Content type: Research article

    Published on:

  2. Some parenteral iron therapies have been found to be associated with hypophosphatemia. The mechanism of the decrease in serum phosphate is unknown. The aim of this study is to examine the effect of IV ferric c...

    Authors: Merche Prats, Ramon Font, Carmen García, Carmen Cabré, Manel Jariod and Alberto Martinez Vea

    Citation: BMC Nephrology 2013 14:167

    Content type: Research article

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  3. We previously demonstrated that lovastatin decreases cyst volume and improves kidney function in the Han:SPRD (Cy/+) rat model of ADPKD. Since endothelial dysfunction and inflammatory activity are evident in p...

    Authors: Jelena Klawitter, Iram Zafar, Jost Klawitter, Alexander T Pennington, Jacek Klepacki, Berenice Y Gitomer, Robert W Schrier, Uwe Christians and Charles L Edelstein

    Citation: BMC Nephrology 2013 14:165

    Content type: Research article

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  6. Thrombotic thrombocytopenic purpura (TTP) is frequently associated with renal abnormalities, but there have been few reports about renal abnormalities in patients with hereditary TTP. In particular, little is ...

    Authors: Koki Mise, Yoshifumi Ubara, Masanori Matsumoto, Keiichi Sumida, Rikako Hiramatsu, Eiko Hasegawa, Masayuki Yamanouchi, Noriko Hayami, Tatsuya Suwabe, Junichi Hoshino, Naoki Sawa, Kenichi Ohashi, Koichi Kokame, Toshiyuki Miyata, Yoshihiro Fujimura and Kenmei Takaichi

    Citation: BMC Nephrology 2013 14:156

    Content type: Case report

    Published on:

  7. The aim of this study was to describe the findings of renal biopsies from a large nephrology center in Iasi, Romania, performed between 2005 and 2010. We compared these findings with our previous ones, from 19...

    Authors: Carmen Volovăt, Irina Cãruntu, Camelia Costin, Alina Stefan, Raluca Popa, Simona Volovăt, Dimitrie Siriopol, Luminita Voroneanu, Ionut Nistor, Liviu Segall and Adrian Covic

    Citation: BMC Nephrology 2013 14:148

    Content type: Research article

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  8. Zinc-alpha2-glycoprotein (AZGP1) is a secreted protein which is synthesized in a variety of cell types. AZGP1 has functionally been implicated in lipid metabolism, the regulation of cell cycling and cancer pro...

    Authors: Inga Sörensen-Zender, Jan Beneke, Bernhard MW Schmidt, Jan Menne, Hermann Haller and Roland Schmitt

    Citation: BMC Nephrology 2013 14:145

    Content type: Research article

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  9. It is important to ensure an adequate sodium and volume balance in neurosurgical patients in order to avoid the worsening of brain injury.

    Authors: Valeria Corradetti, Pasquale Esposito, Teresa Rampino, Marilena Gregorini, Carmelo Libetta, Francesca Bosio, Teresa Valsania, Eleonora Francesca Pattonieri, Chiara Rocca, Stefania Bianzina and Antonio Dal Canton

    Citation: BMC Nephrology 2013 14:140

    Content type: Case report

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  10. Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication following coronary bypass graft (CABG) surgery. Multi-factorial causes of CSA-AKI involve oxidative stress and inflammation. Er...

    Authors: Adis Tasanarong, Soodkate Duangchana, Sangduen Sumransurp, Boonlawat Homvises and Opas Satdhabudha

    Citation: BMC Nephrology 2013 14:136

    Content type: Research article

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  11. Despite a confirmed association between restless legs syndrome (RLS) and end-stage renal disease (ESRD), there is no study on patients presenting with nephrotic syndrome (NS). To investigate the frequency of R...

    Authors: Alexandre Braga Libório, João Paulo Lima Santos, Natália Feitosa Arraes Minete, Cecília Alencar de Diógenes, Luiza de Andrade Braga Farias and Veralice Meireles Sales de Bruin

    Citation: BMC Nephrology 2013 14:113

    Content type: Research article

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  12. Chronic kidney disease (CKD) is known to expose the patient to a high risk of death due to cardiovascular and infective causes. In parallel, septic shock is a major challenge for cardiovascular and immune syst...

    Authors: Julien Maizel, Romain Deransy, Benedicte Dehedin, Edouard Secq, Elie Zogheib, Elisabeth Lewandowski, Chritstophe Tribouilloy, Ziad A Massy, Gabriel Choukroun and Michel Slama

    Citation: BMC Nephrology 2013 14:77

    Content type: Research article

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  13. The Chimney graft (CG) procedure is one of the novel modification techniques of the endovascular aneurysm repair (EVAR) surgery to treat suprarenal and juxtarenal abdominal aortic aneurysms. Other indications ...

    Authors: Amir Gal-Oz, Yehuda G Wolf, Galia Rosen, Haggai Sharon, Idit F Schwartz and Gil Chernin

    Citation: BMC Nephrology 2013 14:71

    Content type: Case report

    Published on:

  14. Pulmonary renal syndrome (PRS), denoting the presence of diffuse alveolar hemorrhage and glomerulonephritis as manifestations of systemic autoimmune disease, is very rare in childhood. The coexistence of circu...

    Authors: Radovan Bogdanović, Predrag Minić, Jasmina Marković-Lipkovski, Nataša Stajić, Nataša Savić and Milan Rodić

    Citation: BMC Nephrology 2013 14:66

    Content type: Case report

    Published on:

  15. Steroid-sensitive idiopathic nephrotic syndrome (SSINS) is most often encountered in sporadic cases of minimal change disease (MCD). Only rare cases of familial forms of MCD have been reported and most of them...

    Authors: Hassib Chehade, Francois Cachat, Eric Girardin, Samuel Rotman, Antonio Jorge Correia, Florence Fellmann and Olivier Bonny

    Citation: BMC Nephrology 2013 14:65

    Content type: Case report

    Published on:

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As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time. Thank you.

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