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Dialysis and Transplantation

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  1. Whereas in many parts of the world a low protein diet (LPD, 0.6-0.8 g/kg/day) is routinely prescribed for the management of patients with non-dialysis-dependent chronic kidney disease (CKD), this practice is i...

    Authors: Kamyar Kalantar-Zadeh, Linda W. Moore, Amanda R. Tortorici, Jason A. Chou, David E. St-Jules, Arianna Aoun, Vanessa Rojas-Bautista, Annelle K. Tschida, Connie M. Rhee, Anuja A. Shah, Susan Crowley, Joseph A. Vassalotti and Csaba P. Kovesdy

    Citation: BMC Nephrology 2016 17:90

    Content type: Correspondence

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  2. This review provides an overview of the development, implementation and practise of low protein diets (LPD) in Sweden. While the current practice is discussed in general terms emphasizing the interplay between...

    Authors: Sintra Eyre, Gerd Faxén-Irving, Per-Ola Attman, Marie Evans, Karin Windahl, Sigrid Wegener, Charlotte Andersén, Karin Nykvist-Raanaes, Sara Einemo and Juan-Jesus Carrero

    Citation: BMC Nephrology 2016 17:89

    Content type: Correspondence

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  3. This paper describes the 30-year experience on nutritional management of non-dialysis dependent chronic kidney disease (CKD) patients in a public outpatient clinic located in the city of São Paulo, Brazil. A t...

    Authors: Lilian Cuppari, Fabiana Baggio Nerbass, Carla Maria Avesani and Maria Ayako Kamimura

    Citation: BMC Nephrology 2016 17:85

    Content type: Correspondence

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  4. Among adult kidney transplant recipients, non-adherence to immunosuppressive medications is the leading predictor of poor outcomes, including rejection, kidney loss, and death. An alarming one-third of kidney ...

    Authors: Cynthia L. Russell, Shirley Moore, Donna Hathaway, An-Lin Cheng, Guoqing Chen and Kathy Goggin

    Citation: BMC Nephrology 2016 17:84

    Content type: Study protocol

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  5. Haemodialysis (HD) is one of the life-saving options for patients with end stage renal disease but demand for this treatment exceeds capacity in publicly funded hospitals. One novel approach to addressing this...

    Authors: Julie Y. Chen, Eric Y. F. Wan, Karina H. Y. Chan, Anca K. C. Chan, Frank W. K. Chan and Cindy L. K. Lam

    Citation: BMC Nephrology 2016 17:79

    Content type: Study protocol

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  6. Dietary therapy represents an important tool in the management of chronic kidney disease (CKD), mainly through a balanced reduction of protein intake aimed at giving the remnant nephrons in damaged kidneys a “...

    Authors: Giorgina Barbara Piccoli, Irene Capizzi, Federica Neve Vigotti, Filomena Leone, Claudia D’Alessandro, Domenica Giuffrida, Marta Nazha, Simona Roggero, Nicoletta Colombi, Giuseppe Mauro, Natascia Castelluccia, Adamasco Cupisti and Paolo Avagnina

    Citation: BMC Nephrology 2016 17:76

    Content type: Review

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  7. Patients with end-stage renal disease (ESRD) commonly suffer from severe fatigue, which strongly impacts their quality of life (QoL). Although fatigue is often attributed to disease- and treatment characterist...

    Authors: Wieke E. van der Borg, Karen Schipper and Tineke A. Abma

    Citation: BMC Nephrology 2016 17:73

    Content type: Study protocol

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  8. The multi-racial and multi-ethnic population of South Africa has significant variation in their nutritional habits with many black South Africans undergoing a nutritional transition to Western type diets. In t...

    Authors: Oluwatoyin I. Ameh, Lynette Cilliers and Ikechi G. Okpechi

    Citation: BMC Nephrology 2016 17:68

    Content type: Correspondence

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  9. Low protein diets (LPD) have long been prescribed to chronic kidney disease patients with the goals of improving metabolic abnormalities and postpone the start of maintenance dialysis.

    Authors: Denis Fouque, Jing Chen, Wei Chen, Liliana Garneata, SJ Hwang, Kamyar Kalantar-Zadeh, Joel D. Kopple, William E. Mitch, Giorgina Piccoli, Vladimir Teplan and Philippe Chauveau

    Citation: BMC Nephrology 2016 17:63

    Content type: Review

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  10. Renal replacement therapy (RRT) is growing by 10 % per year in Russia, but pre-dialysis care which can retard CKD progression and delay the start of RRT remains limited. We evaluate the effect of Essential Ami...

    Authors: Alexander Zemchenkov and Irina N. Konakova

    Citation: BMC Nephrology 2016 17:62

    Content type: Research article

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  11. Cardiovascular complications represent a major cause of morbidity and mortality for patients who received kidney transplantation (KT). However, the impact of KT and chronic immunosuppression on platelet respon...

    Authors: Clotilde Muller, Nathan Messas, Peggy Perrin, Jerome Olagne, Gabriela Gautier-Vargas, Noelle Cognard, Sophie Caillard, Bruno Moulin and Olivier Morel

    Citation: BMC Nephrology 2016 17:58

    Content type: Research article

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  12. Shared decision making is nowadays acknowledged as an essential step when deciding on starting renal replacement therapy. Valid risk stratification of prognosis is, besides discussing quality of life, crucial ...

    Authors: Patrick Peeters, Wim Van Biesen, Nic Veys, Wim Lemahieu, Bart De Moor and Johan De Meester

    Citation: BMC Nephrology 2016 17:41

    Content type: Research article

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  13. Neck of femur fractures are associated with high mortality and have increased prevalence in dialysis patients. Delays in operating on dialysis patients can occur as a result of logistical or medical issues; it...

    Authors: Oscar Swift, Anouska Ayub, Suresh Mathavakkannan and Nick de Roeck

    Citation: BMC Nephrology 2016 17:26

    Content type: Research article

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  14. Emphysematous cholecystitis is a rare variant of acute cholecystitis with a high mortality rate. The combination of emphysematous cholecystitis, liver abscess and pneumoperitoneum are even rarer. Herein we pre...

    Authors: Chen-Yi Liao, Chi-chang Tsai, Wu-Hsien Kuo, Ren-Jy Ben, Ho-Cheng Lin, Ching-Chang Lee, Kuan-Jen Su, Han-En Wang, Chih-Chiang Wang, I-Hung Chen, Shang-Tao Chien and Ming-Kai Tsai

    Citation: BMC Nephrology 2016 17:23

    Content type: Case report

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  15. Intradialytic hypotension (IDH) is considered one of the most frequent complications of haemodialysis with an estimated prevalence of 20–50 %, but studies investigating its exact prevalence are scarce. A compl...

    Authors: Johanna Kuipers, Jurjen K. Oosterhuis, Wim P. Krijnen, Judith J. Dasselaar, Carlo A. J. M. Gaillard, Ralf Westerhuis and Casper F. M. Franssen

    Citation: BMC Nephrology 2016 17:21

    Content type: Research article

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  16. It is uncertain whether switching to frequent nocturnal hemodialysis improves cognitive function in well-dialyzed patients and how this compares to patients who receive a kidney transplant.

    Authors: Bradley S. Dixon, John M. VanBuren, James R. Rodrigue, Robert S. Lockridge, Robert Lindsay, Christopher Chan, Michael V. Rocco, Jacob J. Oleson, Leigh Beglinger, Kevin Duff, Jane S. Paulsen and John B. Stokes

    Citation: BMC Nephrology 2016 17:12

    Content type: Research article

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  17. Treatment of end stage renal disease has an impact on patients’ physical and psychological health, including quality of life (QoL). Nowadays, it is known that reducing the dialysis period has many advantages r...

    Authors: Véronique Sébille, Jean-Benoit Hardouin, Magali Giral, Angélique Bonnaud-Antignac, Philippe Tessier, Emmanuelle Papuchon, Alexandra Jobert, Elodie Faurel-Paul, Stéphanie Gentile, Elisabeth Cassuto, Emmanuel Morélon, Lionel Rostaing, Denis Glotz, Rebecca Sberro-Soussan, Yohann Foucher and Aurélie Meurette

    Citation: BMC Nephrology 2016 17:11

    Content type: Study protocol

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  18. Maintaining optimal fluid balance is essential in haemodialysis (HD) patients but clinical evaluation remains problematic. Other technologies such as bioimpedance are emerging as valuable adjuncts. This study ...

    Authors: Murugan Sivalingam, Enric Vilar, Suresh Mathavakkannan and Ken Farrington

    Citation: BMC Nephrology 2015 16:218

    Content type: Research article

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  19. Rituximab is widely used in kidney transplantation. However, it is not clear whether the conventional doses of maintenance immunosuppressant in rituximab-treated kidney transplantation (KT) are appropriate. In...

    Authors: Chung Hee Baek, Hyosang Kim, Hoon Yu, Eunhye Shin, Hyungjin Cho, Won Seok Yang, Duck Jong Han and Su-Kil Park

    Citation: BMC Nephrology 2015 16:201

    Content type: Research article

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  20. A representative cross-sectional study showed that chronic itch (lasting for a minimum of 6 weeks) affects 25.2 % (point prevalence) of hemodialysis (HD) patients. Pathophysiology and etiology of chronic itch ...

    Authors: Elke Weisshaar, Melanie Weiss, Jutta Passlick-Deetjen, Ulrich Tschulena, Klaudia Maleki and Thomas Mettang

    Citation: BMC Nephrology 2015 16:184

    Content type: Research article

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  21. The prevalence of depression in people receiving haemodialysis is high with estimates varying between 20 and 40 %. There is little research on the effectiveness of antidepressants in dialysis patients with the...

    Authors: Karin Friedli, Michael Almond, Clara Day, Joseph Chilcot, Maria da Silva Gane, Andrew Davenport, Ayman Guirguis, Naomi Fineberg, Benjamin Spencer, David Wellsted and Ken Farrington

    Citation: BMC Nephrology 2015 16:172

    Content type: Study protocol

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  22. Live donor kidney transplantation (LDKT), an optimal therapy for many patients with end-stage kidney disease, is underutilized, particularly by African Americans. Potential recipient difficulties initiating an...

    Authors: Tara S. Strigo, Patti L. Ephraim, Iris Pounds, Felicia Hill-Briggs, Linda Darrell, Matthew Ellis, Debra Sudan, Hamid Rabb, Dorry Segev, Nae-Yuh Wang, Mary Kaiser, Margaret Falkovic, Jill F. Lebov and L. Ebony Boulware

    Citation: BMC Nephrology 2015 16:160

    Content type: Study protocol

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  23. The main short-term advantages of haemodiafiltration (HDF) are supposedly better removal of Beta2-microglobulin (ß2-m) and phosphate, and better haemodynamic stability. The main disadvantage is higher costs. T...

    Authors: Guillaume Jean, Jean-Marc Hurot, Patrik Deleaval, Brice Mayor and Christie Lorriaux

    Citation: BMC Nephrology 2015 16:70

    Content type: Research article

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  24. Chronic kidney disease (CKD) accelerates vascular stiffening related to age. Arterial stiffness may be evaluated measuring the carotid-femoral pulse wave velocity (PWV) or more simply, as recommended by KDOQI,...

    Authors: Igor Salvadé, Sibylle Schätti-Stählin, Eleonora Violetti, Carlo Schönholzer, Claudio Cereghetti, Hugo Zwahlen, Lorenzo Berwert, Michel Burnier and Luca Gabutti

    Citation: BMC Nephrology 2015 16:62

    Content type: Research article

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  25. Multipass hemodialysis (MPHD) is a recently described dialysis modality, involving the use of small volumes of dialysate which are repetitively recycled. Dialysis regimes of 8 hours for six days a week using t...

    Authors: Sunny Eloot, Wim Van Biesen, Mette Axelsen, Griet Glorieux, Robert Smith Pedersen and James Goya Heaf

    Citation: BMC Nephrology 2015 16:57

    Content type: Research article

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  26. People with kidney failure are often deficient in zinc and selenium, but little is known about the optimal way to correct such deficiency.

    Authors: Marcello Tonelli, Natasha Wiebe, Stephanie Thompson, David Kinniburgh, Scott W Klarenbach, Michael Walsh, Aminu K Bello, Labib Faruque, Catherine Field, Braden J Manns and Brenda R Hemmelgarn

    Citation: BMC Nephrology 2015 16:52

    Content type: Research article

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  27. In view of the prevalence of oxidative stress in chronic kidney disease (CKD) patients, the loss of low-molecular-weight biomolecules by hemodialysis and the antioxidant potential of some uremic solutes that a...

    Authors: Renata P Assis, Juliana FA Castro, Vânia O Gutierres, Carlos A Arcaro, Renata S Brotto, Olga MMF Oliveira, Amanda M Baviera and Iguatemy L Brunetti

    Citation: BMC Nephrology 2015 16:50

    Content type: Research article

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  28. Peritoneal fibrosis is a common complication in patients treated with long-term peritoneal dialysis. The aim of this study was to identify the microRNAs (miRNAs) involved in regulation of peritoneal fibrosis i...

    Authors: Fan Lin, Xu Wu, Huidi Zhang, Xiaohan You, Zhoucang Zhang, Rongrong Shao and Chaoxing Huang

    Citation: BMC Nephrology 2015 16:48

    Content type: Research article

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  29. Uremic pruritus is a common and deleterious condition among hemodialysis (HD) patients. Central gating of μ/κ opiate circuitry plays an important role in mediating and countering pruritogenic sensation. The ob...

    Authors: Amale Hawi, Harry Alcorn Jr, Jolene Berg, Carey Hines, Howard Hait and Thomas Sciascia

    Citation: BMC Nephrology 2015 16:47

    Content type: Research article

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  30. Increasing dialysate flow rates (Qd) from 500 to 800 ml/min has been recommended to increase dialysis efficiency. A few publications show that increasing Qd no longer led to an increase in mass transfer area c...

    Authors: Marta Albalate, Rafael Pérez-García, Patricia de Sequera, Elena Corchete, Roberto Alcazar, Mayra Ortega and Marta Puerta

    Citation: BMC Nephrology 2015 16:20

    Content type: Research article

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  31. Kidney injury molecule-1 (KIM-1) is expressed in tubular epithelial cells after injury and may have a role in the development of renal graft fibrosis. In this study we evaluated the molecular and protein expre...

    Authors: Aline Lima Nogare, Francisco Veríssimo Veronese, Virna Nowotny Carpio, Rosangela Munhoz Montenegro, José Alberto Pedroso, Karla Laís Pegas, Luiz Felipe Gonçalves and Roberto Ceratti Manfro

    Citation: BMC Nephrology 2015 16:19

    Content type: Research article

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  32. Haemodialysis patients are at increased risk of exposure to blood borne viruses. To reduce transmission in the UK, all haemodialysis patients are regularly screened, and if susceptible to Hepatitis B virus (HB...

    Authors: Luciana Sowole, Wendy Labbett, Mauli Patel, Aisling O’Riordan, Jennifer Cross, Andrew Davenport and Tanzina Haque

    Citation: BMC Nephrology 2015 16:12

    Content type: Research article

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  33. Mortality rate among patients with stage five chronic kidney disease (CKD) maintained on hemodialysis (HD) is high. Although evidence suggests that use of Vitamin D Receptor Activators (VDRA) in CKD patients i...

    Authors: Piergiorgio Messa, Mario Cozzolino, Diego Brancaccio, Giuseppe Cannella, Fabio Malberti, Anna Maria Costanzo, Umberto di Luzio Paparatti, Vincenzo Festa, Giuliana Gualberti and Sandro Mazzaferro

    Citation: BMC Nephrology 2015 16:11

    Content type: Research article

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  34. Numerous well-established clinical parameters are taken into consideration for the follow-up adaptation of kidney transplant recipients, but there are important disparities between countries, centres and clini...

    Authors: Yohann Foucher, Aurélie Meurette, Pascal Daguin, Angélique Bonnaud-Antignac, Jean-Benoît Hardouin, Sabrina Chailan, Karine Neau, Emmanuelle Papuchon, Sandra Gaboriau, Christophe Legendre, Emmanuel Morélon, Philippe Tessier and Magali Giral

    Citation: BMC Nephrology 2015 16:6

    Content type: Study protocol

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  35. Phosphorus retention plays a pivotal role in the onset of mineral and bone disorders (MBD) in chronic kidney disease (CKD). Phosphorus retention commonly occurs as a result of net intestinal absorption exceedi...

    Authors: Claudia D’Alessandro, Giorgina B Piccoli and Adamasco Cupisti

    Citation: BMC Nephrology 2015 16:9

    Content type: Correspondence

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  36. There is a recent debate on the "transplantability" of ECD (Expanded Criteria Donors) kidneys and the selection criteria used to allocate them to single or double transplantation. Remuzzi et al. have defined a...

    Authors: Carlo Grifasi, Vincenzo D’Alessandro, Maria D’Armiento, Severo Campione, Alessandro Scotti, Luigi Pelosio and Andrea Renda

    Citation: BMC Nephrology 2014 15:207

    Content type: Debate

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  37. AKI frequently develops in sepsis patients, significantly decreasing the overall prognosis. There are currently no diagnostic markers available which reliably predict the prognosis of sepsis-associated AKI. Re...

    Authors: Daniel Patschan, Malte Heeg, Maria Brier, Gunnar Brandhorst, Simon Schneider, Gerhard A Müller and Michael J Koziolek

    Citation: BMC Nephrology 2014 15:203

    Content type: Research article

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  38. This study was performed to evaluate the effectiveness of surveillance for screening and treatment of patients with chronic kidney disease undergoing hemodialysis and colonized by Staphylococcus aureus.

    Authors: Cibele Grothe, Mônica Taminato, Angélica Belasco, Ricardo Sesso and Dulce Barbosa

    Citation: BMC Nephrology 2014 15:202

    Content type: Research article

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  39. Hepatocyte growth factor (HGF) counteracts peritoneal fibrosis in animal models and in-vitro studies, but no study explored effluent HGF in peritoneal dialysis (PD) patients with ultrafiltration failure (UFF)....

    Authors: Ana Paula Bernardo, José C Oliveira, Olívia Santos, Maria J Carvalho, António Cabrita and Anabela Rodrigues

    Citation: BMC Nephrology 2014 15:201

    Content type: Research article

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  40. Serum cystatin C (ScysC) may help predicting cardiovascular outcome not only through its ability to detect renal dysfunction but also through its potential connection to others factors that are directly relate...

    Authors: Miriana Dinic, Nicolas Maillard, Damien Thibaudin, Martin Jannot, Ingrid Masson, Eric Alamartine and Christophe Mariat

    Citation: BMC Nephrology 2014 15:196

    Content type: Research article

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  41. Little is known about patients’ and carers’ experiences of interacting with home haemodialysis (HHD) technology, in terms of user experience, how the design of the technology supports safety and fits with home...

    Authors: Atish Rajkomar, Ken Farrington, Astrid Mayer, Diane Walker and Ann Blandford

    Citation: BMC Nephrology 2014 15:195

    Content type: Research article

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  42. Little is known how health related quality of life (HRQOL) change in the transition from dialysis to renal transplantation (RTX). Longitudinal data addressing the patient-related outcomes are scarce, and parti...

    Authors: Nanna von der Lippe, Bård Waldum, Fredrik B Brekke, Amin AG Amro, Anna Varberg Reisæter and Ingrid Os

    Citation: BMC Nephrology 2014 15:191

    Content type: Research article

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  43. This study was aimed at determining the outcome and examining the association between comorbidities and mortality after intracerebral hemorrhage in chronic dialysis patients.

    Authors: Chun-Yu Lin, Chih-Chiang Chien, Hung-An Chen, Fu-Mei Su, Jhi-Joung Wang, Che-Chuan Wang, Chin-Chen Chu and Yeong-Jang Lin

    Citation: BMC Nephrology 2014 15:186

    Content type: Research article

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  44. Guidance varies regarding the optimal timing of arteriovenous fistula (AVF) creation. The aim of this study was to evaluate the association between uraemia, haemodialysis and early AVF failure.

    Authors: Emma Aitken, Andrew Jackson, Chia Kong, Paul Coats and David Kingsmore

    Citation: BMC Nephrology 2014 15:179

    Content type: Research article

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  45. New information from various clinical settings suggests that tight blood pressure control may not reduce mortality and may be associated with more side effects.

    Authors: Adrian P Abreo, David Glidden, Patricia Painter, Janice Lea, Charles A Herzog, Nancy G Kutner and Kirsten L Johansen

    Citation: BMC Nephrology 2014 15:177

    Content type: Research article

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  46. Cardiovascular disease is a frequent cause of death in peritoneal dialysis patients. Biocompatible peritoneal dialysis solutions with neutral pH have been anticipated to reduce cardiovascular disease more than...

    Authors: Yoshifumi Hamasaki, Kent Doi, Mototsugu Tanaka, Haruki Kume, Yoshitaka Ishibashi, Yutaka Enomoto, Toshiro Fujita, Yukio Homma, Masaomi Nangaku and Eisei Noiri

    Citation: BMC Nephrology 2014 15:173

    Content type: Research article

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  47. Infrequent dialysis, namely once-a-week session combined with very low-protein, low-phosphorus diet supplemented with ketoacids was reported as a useful treatment schedule for ESRD patients with markedly reduc...

    Authors: Stefania Caria, Adamasco Cupisti, Giovanna Sau and Piergiorgio Bolasco

    Citation: BMC Nephrology 2014 15:172

    Content type: Research article

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