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Dialysis and Transplantation

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  1. The Southeastern United States has the lowest kidney transplant rates in the nation, and racial disparities in kidney transplant access are concentrated in this region. The Southeastern Kidney Transplant Coali...

    Authors: Rachel E Patzer, Jennifer Gander, Leighann Sauls, M Ahinee Amamoo, Jenna Krisher, Laura L Mulloy, Eric Gibney, Teri Browne, Laura Plantinga and Stephen O Pastan

    Citation: BMC Nephrology 2014 15:171

    Content type: Study protocol

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  2. Hemodialysis patients (HD) need to adhere to a complex medication regimen. Because their daily pill burden is one of the highest reported, poor compliance is a major cause of therapeutic failure. The primary a...

    Authors: Inbal Cohen-Glickman, Yosef S Haviv and Matan J Cohen

    Citation: BMC Nephrology 2014 15:170

    Content type: Research article

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  3. Uraemia is associated with a highly increased risk of cardiovascular disease. Mannose-binding lectin (MBL) has been shown to be involved in cardiovascular pathophysiology and a protective effect of MBL is sugg...

    Authors: Mads Hornum, Jakob T Bay, Peter Clausen, Jesper Melchior Hansen, Elisabeth R Mathiesen, Bo Feldt-Rasmussen and Peter Garred

    Citation: BMC Nephrology 2014 15:162

    Content type: Research article

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  4. Acute rejection (AR) and acute tubular necrosis (ATN) are main causes of early renal allograft dysfunction. Blood oxygen level-dependent magnetic resonance imaging (BOLD MRI) and Diffusion weighted (DW) MRI ca...

    Authors: Guangyi Liu, Fei Han, Wenbo Xiao, Qidong Wang, Ying Xu and Jianghua Chen

    Citation: BMC Nephrology 2014 15:158

    Content type: Research article

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  5. We conducted this study to determine the erythrocyte glucose-6-phosphate dehydrogenase (G6PD) activity level in patients with end-stage renal disease (ESRD) on maintenance hemodialysis (HD) and to determine th...

    Authors: Mahmoud Husni Ayesh (Haj Yousef), Ahnaf Bataineh, Elham Elamin, Yousef Khader, Khaldoon Alawneh and Mohamad Rababah

    Citation: BMC Nephrology 2014 15:155

    Content type: Research article

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  6. Baroreflex failure syndrome is a rare disorder which causes labile blood pressure, headache, flushing, diaphoresis and emotional lability. It is caused by history of trauma or radiotherapy in the cervical legi...

    Authors: Natsumi Tanabe, Koki Takane, Keitaro Yokoyama, Yudo Tanno, Izumi Yamamoto, Ichiro Ohkido and Takashi Yokoo

    Citation: BMC Nephrology 2014 15:151

    Content type: Case report

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  7. Cancer antigen 125 (CA125) is made by peritoneal mesothelial cells and can be measured in spent dialysate effluent from peritoneal dialysis (PD) patients. It has been suggested that CA125 is a marker of perito...

    Authors: Kwanpeemai Panorchan and Andrew Davenport

    Citation: BMC Nephrology 2014 15:149

    Content type: Research article

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  8. Neutrophil gelatinase-associated lipocalin (NGAL) is a marker for acute kidney injury. We studied whether serum NGAL predicts delayed graft function (DGF) and recovery of kidney function after transplantation.

    Authors: Maria E Hollmen, Lauri E Kyllönen, Jussi Merenmies and Kaija T Salmela

    Citation: BMC Nephrology 2014 15:123

    Content type: Research article

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  9. Patient outcomes have been compared on the basis of the profit status of the dialysis provider (for-profit [FP] and not-for-profit [NFP]). In its annual report, United States Renal Data System (USRDS) provides...

    Authors: Steven M Brunelli, Steven Wilson, Mahesh Krishnan and Allen R Nissenson

    Citation: BMC Nephrology 2014 15:121

    Content type: Research article

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  10. The Sodium Lowering in Dialysate (SoLID) trial is an ongoing a multi-center, prospective, randomised, single-blind (assessor), controlled, parallel assignment clinical trial, enrolling 96 home and self-care he...

    Authors: Joanna Leigh Dunlop, Alain Charles Vandal, Janak Rashme de Zoysa, Ruvin Sampath Gabriel, Lukas Mathias Gerber, Imad Adbi Haloob, Christopher John Hood, John Hamilton Irvine, Philip James Matheson, David Owen Ross McGregor, Kannaiyan Samuel Rabindranath, John Benedict William Schollum, David John Semple and Mark Roger Marshall

    Citation: BMC Nephrology 2014 15:120

    Content type: Study protocol

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  11. We evaluated accuracy of urinary liver type fatty acid-binding protein (L-FABP) for prediction of early allograft function and compared it to neutrophil gelatinase associated lipocalin (NGAL), diuresis and uri...

    Authors: Jernej Pajek, Andrej Škoberne, Klara Šosterič, Barbara Adlešič, Bojan Leskošek, Maja Bučar Pajek, Joško Osredkar and Jelka Lindič

    Citation: BMC Nephrology 2014 15:117

    Content type: Research article

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  12. Survivors of acute kidney injury are at an increased risk of developing irreversible deterioration in kidney function and in some cases, the need for chronic dialysis. We aimed to determine predictors of chron...

    Authors: Ziv Harel, Chaim M Bell, Stephanie N Dixon, Eric McArthur, Matthew T James, Amit X Garg, Shai Harel, Samuel Silver and Ron Wald

    Citation: BMC Nephrology 2014 15:114

    Content type: Research article

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  13. Hyponatremia is known to be a marker of poor prognosis in many clinical conditions. The association between hyponatremia and clinical outcomes in peritoneal dialysis-related peritonitis (PDRP) has not been stu...

    Authors: Min-Hua Tseng, Chih-Jen Cheng, Chih-Chien Sung, Yu-Ching Chou, Pauling Chu, Giien Shuen Chen and Shih-Hua Lin

    Citation: BMC Nephrology 2014 15:113

    Content type: Research article

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  14. Since October 2010, the combination of a heparin-grafted polyacrilonitrile (AN69ST) membrane with a 0.80 mmol/L citric acid-containing dialysate is routinely used in our centre for intermittent haemodialysis, ...

    Authors: Karlien François, Karl Martin Wissing, Rita Jacobs, Dries Boone, Kristine Jacobs and Christian Tielemans

    Citation: BMC Nephrology 2014 15:104

    Content type: Research article

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  15. After renal transplantation, many patients experience adverse effects from maintenance immunosuppressive drugs. When these adverse effects occur, patient adherence with immunosuppression may be reduced and imp...

    Authors: Calvin J Meaney, Ziad Arabi, Rocco C Venuto, Joseph D Consiglio, Gregory E Wilding and Kathleen M Tornatore

    Citation: BMC Nephrology 2014 15:88

    Content type: Research article

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  16. There is no national policy for allocation of kidneys from Donation after circulatory death (DCD) donors in the UK. Allocation is geographical and based on individual/regional centre policies. We have evaluate...

    Authors: Shanka K Benaragama, Teressa Tymkewycz, Biku J John, Andrew Davenport, Ben Lindsey, David Nicol, Jonathon Olsburgh, Martin Drage, Nizam Mamode, Francis Calder, John Taylor, Geoff Koffman, Nicos Kessaris, Mohamed Morsy, Roberto Cacciola, Carmelo Puliatti…

    Citation: BMC Nephrology 2014 15:83

    Content type: Research article

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  17. Many patients on renal replacement therapy (RRT) require parathyroidectomy (PTX). Trends and current rates of PTX on a national level are not known. Furthermore, it is not completely clear which factors influe...

    Authors: Shahriar Akaberi, Naomi Clyne, Gunnar Sterner, Bengt Rippe, Eva Reihnér, Philippe Wagner, Rebecca Rylance, Karl Göran Prütz and Martin Almquist

    Citation: BMC Nephrology 2014 15:75

    Content type: Research article

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  18. Renal transplant recipients frequently experience neurological complications. Whereas ischemic stroke, cerebral haemorrhage or hypertensive encephalopathy often result from vascular alterations prior to transp...

    Authors: Arash Haghikia, Meike Heeren, Clemens Bockmeyer, Bernd Haubitz and Wilfried Gwinner

    Citation: BMC Nephrology 2014 15:59

    Content type: Case report

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  19. Monitoring of volatile organic compounds (VOCs) in exhaled breath shows great potential as a non-invasive method for assessing hemodialysis efficiency. In this work we aim at identifying and quantifying of a w...

    Authors: Paweł Mochalski, Julian King, Matthias Haas, Karl Unterkofler, Anton Amann and Gert Mayer

    Citation: BMC Nephrology 2014 15:43

    Content type: Research article

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  20. Home-based dialysis, including peritoneal dialysis (PD) and home hemodialysis (HHD), is associated with improved health related quality of life and reduced health resource costs. It is uncertain to what extent...

    Authors: Patrick T Keating, Michael Walsh, Christine M Ribic and Kenneth Scott Brimble

    Citation: BMC Nephrology 2014 15:38

    Content type: Research article

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  21. Peritoneal dialysis (PD) therapy is known to induce morphological and functional changes in the peritoneal membrane. Long-term exposure to conventional bio-incompatible dialysate and peritonitis is the main et...

    Authors: Yi-Che Lee, Yau-Sheng Tsai, Shih-Yuan Hung, Tsun-Mei Lin, Sheng-Hsiang Lin, Hung-Hsiang Liou, Hsiang-Chun Liu, Min-Yu Chang, Hsi-Hao Wang, Li-Chun Ho, Yi-Ting Chen, Hsin-Pao Chen, Hong-Arh Fan, Kuang-Wen Liu, Yung-Tang Kung, Hao-Kuang Wang…

    Citation: BMC Nephrology 2014 15:35

    Content type: Research article

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  22. Home-based renal replacement therapy (RRT) [peritoneal dialysis (PD) and home hemodialysis (HHD)] offers independent quality of life and clinical advantages compared to conventional in-center hemodialysis. How...

    Authors: Michael E Schachter, Joanne M Bargman, Michael Copland, Michelle Hladunewich, Karthik K Tennankore, Adeera Levin, Matthew Oliver, Robert P Pauly, Jeffrey Perl, Deborah Zimmerman and Christopher T Chan

    Citation: BMC Nephrology 2014 15:33

    Content type: Study protocol

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  23. The major challenge in ABO-incompatible transplantation is to minimize antibody-mediated rejection. Effective reduction of the anti-ABO blood group antibodies at the time of transplantation has made ABO-incomp...

    Authors: Annelies de Weerd, Alieke Vonk, Hans van der Hoek, Marian van Groningen, Willem Weimar, Michiel Betjes and Madelon van Agteren

    Citation: BMC Nephrology 2014 15:31

    Content type: Case report

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  24. Many patients on maintenance dialysis experience significant sleepiness and fatigue. However, the influence of the hemodialysis (HD) day and circadian rhythms on patients’ symptoms have not been well character...

    Authors: Khaled Abdel-Kader, Manisha Jhamb, Lee Anne Mandich, Jonathan Yabes, Robert M Keene, Scott Beach, Daniel J Buysse and Mark L Unruh

    Citation: BMC Nephrology 2014 15:29

    Content type: Research article

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  25. While fluid overload (FO) and alterations in the autonomic nervous system (ANS) such as hypersympathetic activity, are known risk factors for cardiovascular morbidity and mortality in patients on chronic hemod...

    Authors: Manuela Ferrario, Ulrich Moissl, Francesco Garzotto, Dinna N Cruz, Anna Clementi, Alessandra Brendolan, Ciro Tetta, Emanuele Gatti, Maria G Signorini, Sergio Cerutti and Claudio Ronco

    Citation: BMC Nephrology 2014 15:26

    Content type: Research article

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  26. The natural history of patients commencing dialysis in East Yorkshire is not well characterised and there is little convincing evidence which has studied the impact of potential factors prior to commencement o...

    Authors: Oliver T Browne, Victoria Allgar and Sunil Bhandari

    Citation: BMC Nephrology 2014 15:20

    Content type: Research article

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  27. Malnutrition is associated with an increased risk of cardiovascular death and may cause protein-energy wasting in individuals with chronic kidney disease. A previous study demonstrated that blood cadmium level...

    Authors: Ching-Wei Hsu, Ja-Liang Lin, Dan-Tzu Lin-Tan, Wen-Hung Huang, Kuan-Hsing Chen and Tzung-Hai Yen

    Citation: BMC Nephrology 2014 15:17

    Content type: Research article

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  28. Posterior reversible encephalopathy syndrome (PRES) is a clinical and radiological entity characterized clinically by headache, altered mental status, seizures, visual disturbances, and other focal neurologica...

    Authors: Brett R Graham and George B Pylypchuk

    Citation: BMC Nephrology 2014 15:10

    Content type: Case report

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  29. Repeated exposure to peritoneal dialysis (PD) solutions contributes to cumulative intraperitoneal inflammation and peritoneal injury. The present study aimed to explore the capacity of dialysate interleukin-6(...

    Authors: Yeoungjee Cho, David W Johnson, David A Vesey, Carmel M Hawley, Elaine M Pascoe, Margaret Clarke and Nicholas Topley

    Citation: BMC Nephrology 2014 15:8

    Content type: Research article

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  30. Little is known about the effects of intermittent hemodialysis on microcirculatory perfusion. The aim of this study is to assess the effects of hemodialysis on microvascular perfusion using transcutaneous oxym...

    Authors: Ygal Benhamou, Loic Begarin, Nathalie David, Nicole Cailleux, Catherine Bessin, Herve Lévesque and Stephane Edet

    Citation: BMC Nephrology 2014 15:4

    Content type: Research article

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  31. Australians living in rural areas have lower incidence rates of renal replacement therapy and poorer dialysis survival compared with urban dwellers. This study compares peritoneal dialysis (PD) patient charact...

    Authors: Nicholas A Gray, Blair S Grace and Stephen P McDonald

    Citation: BMC Nephrology 2013 14:278

    Content type: Research article

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  32. There have been major changes in the management of anemia in US hemodialysis patients in recent years. We sought to determine the influence of clinical trial results, safety regulations, and changes in reimbur...

    Authors: Dana C Miskulin, Jing Zhou, Navdeep Tangri, Karen Bandeen-Roche, Courtney Cook, Patti L Ephraim, Deidra C Crews, Julia J Scialla, Stephen M Sozio, Tariq Shafi, Bernard G Jaar and L Ebony Boulware

    Citation: BMC Nephrology 2013 14:264

    Content type: Research article

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  33. Among kidney transplant recipients, non-adherence with immunosuppressive medications frequently precedes allograft loss. We sought to determine the prevalence and correlates of medication non-adherence among k...

    Authors: Francis L Weng, Sheenu Chandwani, Karen M Kurtyka, Christopher Zacker, Marie A Chisholm-Burns and Kitaw Demissie

    Citation: BMC Nephrology 2013 14:261

    Content type: Research article

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  34. Protein-energy wasting (PEW) is common in hemodialysis patients and is a powerful predictor of morbidity and mortality. Although much progress has been made in recent years in identifying the causes and pathog...

    Authors: Justine Magnard, Thibault Deschamps, Christophe Cornu, Anne Paris and Dan Hristea

    Citation: BMC Nephrology 2013 14:259

    Content type: Study protocol

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  35. There is no single model available to predict the long term survival for patients starting renal replacement therapy (RRT). The available models either predict survival on dialysis until transplantation, survi...

    Authors: Aline C Hemke, Martin BA Heemskerk, Merel van Diepen, Willem Weimar, Friedo W Dekker and Andries J Hoitsma

    Citation: BMC Nephrology 2013 14:258

    Content type: Research article

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  36. The best treatment option for end-stage renal disease is usually a transplant, preferably a live donor kidney transplant (LDKT). The most effective ways to educate kidney transplant candidates about the risks,...

    Authors: Francis L Weng, Diane R Brown, John D Peipert, Bart Holland and Amy D Waterman

    Citation: BMC Nephrology 2013 14:256

    Content type: Study protocol

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  37. Dialysis disequilibrium syndrome is characterized by neurological symptoms resulting from cerebral edema, which occurs as a consequence of hemodialysis. Dialysis disequilibrium syndrome most often occurs in pa...

    Authors: Yohei Tsuchida, Takuma Takata, Toshihiko Ikarashi, Noriaki Iino, Junichiro J Kazama and Ichiei Narita

    Citation: BMC Nephrology 2013 14:255

    Content type: Case report

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  38. Several observational studies have evaluated the effect of a single exposure window with blood pressure (BP) medications on outcomes in incident dialysis patients, but whether BP medication prescription patter...

    Authors: Wendy L St Peter, Stephen M Sozio, Tariq Shafi, Patti L Ephraim, Jason Luly, Aidan McDermott, Karen Bandeen-Roche, Klemens B Meyer, Deidra C Crews, Julia J Scialla, Dana C Miskulin, Navdeep Tangri, Bernard G Jaar, Wieneke M Michels, Albert W Wu and L Ebony Boulware

    Citation: BMC Nephrology 2013 14:249

    Content type: Research article

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  39. Elevated cardiac troponin I (TnI) levels are associated with all-cause mortality in stable hemodialysis patients. Their relationship to cardiac-specific death has been inconsistent, and the reason for their el...

    Authors: Ahsan Alam, Andrea Palumbo, Istvan Mucsi, Paul E Barré and Allan D Sniderman

    Citation: BMC Nephrology 2013 14:247

    Content type: Research article

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  40. The aim of the present study was to investigate the impact of the Great East Japan Earthquake on laboratory findings in chronic hemodialysis (HD) patients in Fukushima.

    Authors: Nobuhiro Haga, Junya Hata, Michihiro Yabe, Kei Ishibashi, Norio Takahashi, Ken Kumagai, Souichiro Ogawa, Masao Kataoka, Hidenori Akaihata and Yoshiyuki Kojima

    Citation: BMC Nephrology 2013 14:239

    Content type: Research article

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  41. Recent guidelines suggest the adoption of regional citrate anticoagulation (RCA) as first choice CRRT anticoagulation modality in patients without contraindications for citrate. Regardless of the anticoagulati...

    Authors: Santo Morabito, Valentina Pistolesi, Luigi Tritapepe, Elio Vitaliano, Laura Zeppilli, Francesca Polistena, Enrico Fiaccadori and Alessandro Pierucci

    Citation: BMC Nephrology 2013 14:232

    Content type: Research article

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  42. Bixalomer (BXL) was developed to improve gastrointestinal symptoms and reduce constipation, relative to sevelamer hydrochloride, in hemodialysis patients. We prospectively evaluated the safety and effectivenes...

    Authors: Shingo Hatakeyama, Hiromi Murasawa, Takuma Narita, Masaaki Oikawa, Naoki Fujita, Hiromichi Iwamura, Joutaro Mikami, Yuta Kojima, Tendo Sato, Ken Fukushi, Yusuke Ishibashi, Yasuhiro Hashimoto, Takuya Koie, Hisao Saitoh, Tomihisa Funyu and Chikara Ohyama

    Citation: BMC Nephrology 2013 14:222

    Content type: Research article

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  43. Poor sleep quality (SQ) and daytime sleepiness (DS) are common in renal transplant (RTx) recipients; however, related data are rare. This study describes the prevalence and frequency of self-reported sleep dis...

    Authors: Hanna Burkhalter, Daniel P Brunner, Anna Wirz-Justice, Christian Cajochen, Terri E Weaver, Jürg Steiger, Thomas Fehr, Reto M Venzin and Sabina De Geest

    Citation: BMC Nephrology 2013 14:220

    Content type: Research article

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  44. Blood transfusions have the potential to improve graft survival, induce sensitization, and transmit infections. Current clinical practice is to minimize transfusions in renal transplantation candidates, but it...

    Authors: Juan C Scornik, Jonathan S Bromberg, Douglas J Norman, Mayank Bhanderi, Matthew Gitlin and Jeffrey Petersen

    Citation: BMC Nephrology 2013 14:217

    Content type: Research article

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  45. The majority of bicarbonate based dialysis fluids are acidified with acetate. Citrate, a well known anticoagulant and antioxidant, has been suggested as a biocompatible alternative. The objective of this study...

    Authors: Gunilla Grundström, Anders Christensson, Maria Alquist, Lars-Göran Nilsson and Mårten Segelmark

    Citation: BMC Nephrology 2013 14:216

    Content type: Research article

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  46. Despite the evidence that phosphate binder (PB) is associated with improved outcomes many hemodialysis patients do not adhere to prescribed PB regimen. Therefore, barriers to PB adherence should be identified ...

    Authors: Maria Tereza Silveira Martins, Luciana Ferreira Silva, Angiolina Kraychete, Dandara Reis, Lidiane Dias, Gabriel Schnitman, Lívia Oliveira, Gildete Barreto Lopes and Antonio Alberto Lopes

    Citation: BMC Nephrology 2013 14:208

    Content type: Research article

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  47. Polyomavirus BK nephropathy (PyVAN) remains an important cause of early graft dysfunction and graft loss in kidney transplantation.

    Authors: Johannes Jacobi, Antonina Prignitz, Maike Büttner, Klaus Korn, Alexander Weidemann, Karl F Hilgers, Katharina Heller, Joachim Velden, Antje Knöll, Bernd Wullich, Christoph May, Kai-Uwe Eckardt and Kerstin U Amann

    Citation: BMC Nephrology 2013 14:207

    Content type: Research article

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  48. Exercise during hemodialysis treatments improves physical function, markers of cardiovascular disease and quality of life. However, exercise programs are not a part of standard therapy in the vast majority of ...

    Authors: Paul N Bennett, Robin M Daly, Steve F Fraser, Terry Haines, Robert Barnard, Cherene Ockerby and Bridie Kent

    Citation: BMC Nephrology 2013 14:204

    Content type: Study protocol

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  49. Post-transplantation encapsulating peritoneal sclerosis (EPS) causing bowel obstruction has been identified as a serious complication after kidney transplantation in patients previously treated with peritoneal...

    Authors: Sayed Meelad Habib, Frank Johan Marinus Frederik Dor, Mario Richard Korte, Sander Martijn Hagen and Michiel Gerardus Henricus Betjes

    Citation: BMC Nephrology 2013 14:203

    Content type: Case report

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