Skip to content


Epidemiology and Health Outcomes

Section edited by Bernard Jaar

Page 1 of 7

  1. Content type: Research article

    After two-years of follow-up of 263 apparently healthy 18- to 30-year-old men in communities affected by Mesoamerican nephropathy (MeN), we identified three distinct case groups: a subgroup with (i) establishe...

    Authors: Marvin Gonzalez-Quiroz, Evangelia-Theano Smpokou, Neil Pearce, Ben Caplin and Dorothea Nitsch

    Citation: BMC Nephrology 2019 20:21

    Published on:

  2. Content type: Research article

    Use of routine medical care (RMC) is advocated to address ethnic/racial disparities in chronic kidney disease (CKD) risks, but use is less frequent among African Americans. Factors associated with low RMC use ...

    Authors: Clarissa J. Diamantidis, Clemontina A. Davenport, Joseph Lunyera, Nrupen Bhavsar, Julia Scialla, Rasheeda Hall, Crystal Tyson, Mario Sims, Tara Strigo, Neil R. Powe and L. Ebony Boulware

    Citation: BMC Nephrology 2019 20:11

    Published on:

  3. Content type: Research article

    There is a paucity of specific data on early stages of chronic kidney disease (CKD) among Asian Americans (AAs). The objective of this study was to examine the independent association of Asian race/ethnicity a...

    Authors: Merle Kataoka-Yahiro, James Davis, Krupa Gandhi, Connie M. Rhee and Victoria Page

    Citation: BMC Nephrology 2019 20:10

    Published on:

  4. Content type: Research article

    Experimental studies have shown that exposure to incense burning may have deleterious effects on kidney function and architecture. However, the association between chronic exposure to incense smoke and risk of...

    Authors: Ting-Ting Geng, Tazeen Hasan Jafar, Jian-Min Yuan and Woon-Puay Koh

    Citation: BMC Nephrology 2019 20:9

    Published on:

  5. Content type: Research article

    The optimal treatment algorithm for iron therapy and the use of erythropoiesis-stimulating agents (ESA) in anemic hemodialysis (HD) patients has not been established. Hemoglobin (Hb) target levels can be achie...

    Authors: Maciej Drozdz, André Weigert, Fatima Silva, João Frazão, Abdulkareem Alsuwaida, Mahesh Krishnan, Werner Kleophas, Szymon Brzosko, Fredrik K. Johansson and Stefan H. Jacobson

    Citation: BMC Nephrology 2019 20:5

    Published on:

  6. Content type: Research article

    Estimated glomerular filtration rate (eGFR) is the clinical standard for assessing kidney function and staging chronic kidney disease. Automated reporting of eGFR using the Modification of Diet in Renal Diseas...

    Authors: Kristine E. Lynch, Ji won Chang, Michael E. Matheny, Alexander Goldfarb, Olga Efimova, Gregorio Coronado and Scott L. DuVall

    Citation: BMC Nephrology 2018 19:380

    Published on:

  7. Content type: Research article

    Recent studies have shown associations between contrast-induced acute kidney injury (CI-AKI) and increased risk of adverse clinical outcomes in acute coronary syndrome (ACS) patients undergoing percutaneous co...

    Authors: Yi Yang, Kaisha C. George, Ran Luo, Yichun Cheng, Weifeng Shang, Shuwang Ge and Gang Xu

    Citation: BMC Nephrology 2018 19:374

    Published on:

  8. Content type: Research article

    IgA nephropathy (IgAN) is one of the most common forms of idiopathic glomerular diseases and might lead to end-stage kidney disease. Accurate and non-invasive biomarkers for early diagnosis are required for ea...

    Authors: Zhengguang Guo, Zhao Wang, Chen Lu, Shufen Yang, Haidan Sun, Reziw, Yu Guo, Wei Sun and Hua Yue

    Citation: BMC Nephrology 2018 19:358

    Published on:

  9. Content type: Research article

    The effect of chronic hepatitis B virus (HBV) infection on the risk of chronic kidney disease (CKD) is controversial. We examined the prospective association between hepatitis B surface antigen (HBsAg) serolog...

    Authors: Yun Soo Hong, Seungho Ryu, Yoosoo Chang, Miguel Caínzos-Achirica, Min-Jung Kwon, Di Zhao, Tariq Shafi, Mariana Lazo, Roberto Pastor-Barriuso, Hocheol Shin, Juhee Cho and Eliseo Guallar

    Citation: BMC Nephrology 2018 19:353

    Published on:

  10. Content type: Research article

    Surgery is one of the leading causes of acute kidney injury (AKI) in hospitalized patients. Major abdominal surgery has the second higher incidences of AKI, after cardiac surgery. AKI results from a complex in...

    Authors: Joana Gameiro, José Agapito Fonseca, Joana Monteiro Dias, Joana Milho, Rosário Rosa, Sofia Jorge and José António Lopes

    Citation: BMC Nephrology 2018 19:320

    Published on:

  11. Content type: Research article

    The objective of the study was to examine overall anemia management trends in non-dialysis patients with chronic kidney disease (CKD) from 2006 to 2015, and to evaluate the impact of Trial to Reduced Cardiovas...

    Authors: Haesuk Park, Xinyue Liu, Linda Henry, Jeffrey Harman and Edward A. Ross

    Citation: BMC Nephrology 2018 19:318

    Published on:

  12. Content type: Research article

    Patients with end stage renal disease have a high all-cause and cardiovascular mortality. Secondary hyperparathyroidism and vitamin D deficiency are considered part of the mechanism for the excess mortality ob...

    Authors: Jo-Yen Chao, Hsu-Chih Chien, Te-Hui Kuo, Yu-Tzu Chang, Chung-Yi Li, Ming-Cheng Wang and Yea-Huei Kao Yang

    Citation: BMC Nephrology 2018 19:309

    Published on:

  13. Content type: Research article

    Patients on hemodialysis are at high risk for hepatitis C virus (HCV) infection if measures for effective control of HCV infection in the hemodialysis environment are not implemented. Whereas in developed coun...

    Authors: Xhevat Jakupi, Jana Mlakar, Maja M. Lunar, Katja Seme, Ibrahim Rudhani, Lul Raka, Adriana Vince and Mario Poljak

    Citation: BMC Nephrology 2018 19:304

    Published on:

  14. Content type: Research article

    Early detection and treatment of chronic kidney disease (CKD) and its risk factors improves outcomes; however, many high-risk individuals lack access to healthcare. The National Kidney Foundation of Illinois (...

    Authors: Swati Lederer, Laurie Ruggiero, Nicole M. Sisen, Nancy Lepain, Kate Grubbs O’Connor, Yamin Wang, Jinsong Chen, James P. Lash and Michael J. Fischer

    Citation: BMC Nephrology 2018 19:295

    Published on:

  15. Content type: Research article

    Recent studies have suggested that cardiometabolic index (CMI), a novel estimate of visceral adipose tissue, could be of use in the evaluation of cardiovascular risk factors. However, the potential utility and...

    Authors: Hao-Yu Wang, Wen-Rui Shi, Xin Yi, Shu-Ze Wang, Si-Yuan Luan and Ying-Xian Sun

    Citation: BMC Nephrology 2018 19:294

    Published on:

  16. Content type: Research article

    Chronic kidney disease (CKD) is becoming a major public health problem around the world. But the prevalence has not been reported in South Asian region as a whole. This study aimed to systematically review the...

    Authors: Mehedi Hasan, Ipsita Sutradhar, Rajat Das Gupta and Malabika Sarker

    Citation: BMC Nephrology 2018 19:291

    Published on:

  17. Content type: Research article

    In a recent study we demonstrated that low birth weight (LBW) was associated with increased risk of progressive IgA nephropathy (IgAN). In the present study we investigate whether this could be explained by di...

    Authors: Paschal Ruggajo, Sabine Leh, Einar Svarstad, Hans-Peter Marti and Bjørn Egil Vikse

    Citation: BMC Nephrology 2018 19:287

    Published on:

  18. Content type: Research article

    Acute kidney injury (AKI) is common in cirrhotic patients and is associated with negative outcomes. The aim of this study was to evaluate the presence of AKI and its progression according to KDIGO (Kidney Dise...

    Authors: Paulo Ricardo Gessolo Lins, Wallace Stwart Carvalho Padilha, Carolina Frade Magalhaes Giradin Pimentel, Marcelo Costa Batista and Aécio Flávio Teixeira de Gois

    Citation: BMC Nephrology 2018 19:277

    Published on:

  19. Content type: Research article

    Utilization of home hemodialysis (HHD) is low in Europe. The Knowledge to Improve Home Dialysis Network in Europe (KIHDNEy) is a multi-center study of HHD patients who have used a transportable hemodialysis ma...

    Authors: Shashidhar Cherukuri, Maria Bajo, Giacomo Colussi, Roberto Corciulo, Hafedh Fessi, Maxence Ficheux, Maria Slon, Eric Weinhandl and Natalie Borman

    Citation: BMC Nephrology 2018 19:262

    Published on:

  20. Content type: Research article

    Estimates of the incidence of glomerulonephritis (GN) and end-stage renal disease (ESRD) in an Iraqi population are compared with the United States (US) and Jordan.

    Authors: Alaa A Ali, Dana A Sharif, Safa E Almukhtar, Kais Hasan Abd, Zana Sidiq M Saleem and Michael D Hughson

    Citation: BMC Nephrology 2018 19:257

    Published on:

  21. Content type: Research article

    Chronic Kidney Disease (CKD) is common and its prevalence has increased steadily over several decades. Monitoring of rates and severity of CKD across populations is critical for policy development and resource...

    Authors: Mariette J Chartier, Navdeep Tangri, Paul Komenda, Randy Walld, Ina Koseva, Charles Burchill, Kari-Lynne McGowan and Allison Dart

    Citation: BMC Nephrology 2018 19:255

    Published on:

  22. Content type: Research article

    Few investigations have evaluated the incremental usefulness of multiple biomarkers representing varying physiological pathways for predicting risk of renal outcomes in African Americans.

    Authors: Stanford E. Mwasongwe, Bessie Young, Aurelian Bidulescu, Mario Sims, Adolfo Correa and Solomon K. Musani

    Citation: BMC Nephrology 2018 19:239

    Published on:

  23. Content type: Research article

    Iron deficiency is highly prevalent in chronic kidney disease (CKD) patients. In clinical practice, iron deficiency is defined based on a combination of two commonly used markers, ferritin and transferrin satu...

    Authors: Michele F. Eisenga, Ilja M. Nolte, Peter van der Meer, Stephan J. L. Bakker and Carlo A. J. M. Gaillard

    Citation: BMC Nephrology 2018 19:225

    Published on:

  24. Content type: Research article

    To address a current paucity of European data, this study developed equations to predict risks of mortality, major adverse cardiac events (MACE) and renin angiotensin-aldosterone system inhibitor (RAASi) disco...

    Authors: Hans Furuland, Phil McEwan, Marc Evans, Cecilia Linde, Daniel Ayoubkhani, Ameet Bakhai, Eirini Palaka, Hayley Bennett and Lei Qin

    Citation: BMC Nephrology 2018 19:211

    Published on:

  25. Content type: Research article

    Obesity emerged as the leading global health concern in 2017. Although higher body mass index (BMI) is a health risk in the general population, its implications for chronic kidney disease (CKD) are not entirel...

    Authors: Samuel Chan, Anne Cameron, Zaimin Wang, Sree K. Venuthurupalli, Ken S. Tan, Helen G. Healy and Wendy E. Hoy

    Citation: BMC Nephrology 2018 19:209

    Published on:

  26. Content type: Research article

    Minimal change disease (MCD) is a common cause of the nephrotic syndrome in adults with limited evidence on its treatment and prognosis. We examined the presenting characteristics, treatments, and outcomes of ...

    Authors: Anthony Fenton, Stuart W. Smith and Peter Hewins

    Citation: BMC Nephrology 2018 19:207

    Published on:

  27. Content type: Research article

    Chronic kidney disease (CKD) is often asymptomatic in its early stages but is indicated and is diagnosed with an estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73m2. Certain sociodemographic groups are...

    Authors: Irene Ma, Maggie Guo, Daniel Muruve, Hallgrimur Benediktsson and Christopher Naugler

    Citation: BMC Nephrology 2018 19:198

    Published on:

  28. Content type: Research article

    Dialysis is often initiated in the hospital during episodes of acute kidney injury and critical illness. Little is known about how patients or their surrogate decision makers feel about dialysis initiation in ...

    Authors: Amar D. Bansal, Nina R. O’Connor and David J. Casarett

    Citation: BMC Nephrology 2018 19:197

    Published on:

  29. Content type: Research article

    Both dialysis facilities and hospitals are accountable for 30-day hospital readmissions among U.S. hemodialysis patients. We examined the association of post-hospitalization processes of care at hemodialysis f...

    Authors: Laura C. Plantinga, Tahsin Masud, Janice P. Lea, John M. Burkart, Christopher M. O’Donnell and Bernard G. Jaar

    Citation: BMC Nephrology 2018 19:186

    Published on:

  30. Content type: Research article

    Knowing how chronic kidney disease (CKD) patients talk about their encounters with providers (i.e., their discourse) can inform the important clinical goal of engaging patients in their chronic disease self-ma...

    Authors: Ann E. Vandenberg, Katharina V. Echt, Theodore M. Johnson II and C. Barrett Bowling

    Citation: BMC Nephrology 2018 19:183

    Published on:

  31. Content type: Research article

    There are conflicting reports on the impact of HIV in the era of combined antiretroviral (c-ART) on survival of patient with ESKD. We aimed to compare the one-year survival of HIV positive patients to that of ...

    Authors: Marie Patrice Halle, Anais Mfoula Edjomo, Hermine Fouda, Hilaire Djantio, Noel Essomba and Gloria Enow Ashuntantang

    Citation: BMC Nephrology 2018 19:166

    Published on:

  32. Content type: Research article

    According to the literature the three stone diseases, sialolithiasis (SL), urolithiasis (UL) and cholelithiasis (CL) share comorbidities. We assess familial and spouse risks between these stone disease and com...

    Authors: Kari Hemminki, Otto Hemminki, Anni I. M. Koskinen, Asta Försti, Kristina Sundquist, Jan Sundquist and Xinjun Li

    Citation: BMC Nephrology 2018 19:158

    Published on:

  33. Content type: Research article

    Hematuria is associated with chronic kidney disease (CKD), but has rarely been examined as a risk factor for CKD progression. We explored whether individuals with hematuria had worse outcomes compared to those...

    Authors: Paula F. Orlandi, Naohiko Fujii, Jason Roy, Hsiang-Yu Chen, L. Lee Hamm, James H. Sondheimer, Jiang He, Michael J. Fischer, Hernan Rincon-Choles, Geetha Krishnan, Raymond Townsend, Tariq Shafi, Chi-yuan Hsu, John W. Kusek, John T. Daugirdas and Harold I. Feldman

    Citation: BMC Nephrology 2018 19:150

    Published on:

  34. Content type: Research article

    Chronic kidney disease (CKD) is highly prevalent but identification of patients at high risk for fast CKD progression before reaching end-stage renal disease in the short-term has been challenging. Whether fac...

    Authors: Alan S. Go, Jingrong Yang, Thida C. Tan, Claudia S. Cabrera, Bergur V. Stefansson, Peter J. Greasley and Juan D. Ordonez

    Citation: BMC Nephrology 2018 19:146

    Published on:

  35. Content type: Research article

    This study describes the time trend of renal replacement therapy for end-stage renal disease (ESRD) in the Provence-Alpes Côte d’Azur region (PACA) between 2004 and 2015, and forecasts up to 2030.

    Authors: Anne-Claire Durand, Elisabeth Jouve, Jean-Christophe Delarozière, Mohamed Boucekine, Ghizlane Izaaryene, Adeline Crémades, Franck Mazoué, Bénédicte Devictor, Asmatullah Kakar, Roland Sambuc, Philippe Brunet and Stéphanie Gentile

    Citation: BMC Nephrology 2018 19:141

    Published on:

  36. Content type: Research article

    Chronic kidney disease (CKD) is global health concern and priority. It is the 12th leading cause of death worldwide. Protein Energy Wasting occurs in 20–25% of patients with chronic kidney disease and can lead...

    Authors: Lydia Namuyimbwa, Collins Atuheire, Joel Okullo and Robert Kalyesubula

    Citation: BMC Nephrology 2018 19:139

    Published on:

  37. Content type: Research article

    A combination of safety concerns and labeling changes impacted use of erythropoiesis-stimulating agents (ESAs) in renal anemia. Data regarding contemporary utilization in pre-dialysis chronic kidney disease (C...

    Authors: Heide A. Stirnadel-Farrant, Jiacong Luo, Lata Kler, Borut Cizman, Delyth Jones, Steven M. Brunelli and Alexander R. Cobitz

    Citation: BMC Nephrology 2018 19:135

    Published on:

  38. Content type: Research article

    The high mortality and cardiovascular disease (CVD) burden in patients with end-stage renal disease (ESRD) is well-documented. Recent literature suggests that acute kidney injury is also associated with CVD. I...

    Authors: Benjamin J. Lee, Chi-yuan Hsu, Rishi V. Parikh, Thomas K. Leong, Thida C. Tan, Sophia Walia, Kathleen D. Liu, Raymond K. Hsu and Alan S. Go

    Citation: BMC Nephrology 2018 19:134

    Published on:

  39. Content type: Research article

    Diabetic nephropathy requires periodic monitoring, dietary modification, and early intervention to prevent the disease severity within limited resource settings. To emphasize the importance of continuous care ...

    Authors: Yun Jung Jang, Yoon Soo Choy, Chung Mo Nam, Ki Tae Moon and Eun-Cheol Park

    Citation: BMC Nephrology 2018 19:127

    Published on:

  40. Content type: Research article

    Accurate contemporary data on the burden of Chronic Kidney Disease (CKD) on the African continent are lacking. We determined the prevalence of CKD in adult populations living in Africa, and variations by stage...

    Authors: Arnaud D. Kaze, Titilayo Ilori, Bernard G. Jaar and Justin B. Echouffo-Tcheugui

    Citation: BMC Nephrology 2018 19:125

    Published on:

  41. Content type: Research article

    People with chronic renal disease are insulin resistant. We hypothesized that in a healthy population, baseline renal function is associated with insulin sensitivity three years later.

    Authors: Soline Siméon, Ziad Massy, Kurt Højlund, Katarina Lalic, Francesca Porcellati, Jacqueline Dekker, John Petrie, Gemma Currie and Beverley Balkau

    Citation: BMC Nephrology 2018 19:124

    Published on:

  42. Content type: Research article

    There are limited data on the associations of circulating angiogenic factors with chronic kidney disease (CKD). We investigate the associations of circulating vascular endothelial growth factor (VEGF)-A, angio...

    Authors: Christopher E. Anderson, L. Lee Hamm, Gem Batuman, Damodar R. Kumbala, Chung-Shiuan Chen, Swapna G. Kallu, Ravi Siriki, Shilpa Gadde, Myra A. Kleinpeter, N. Kevin Krane, Eric E. Simon, Jiang He and Jing Chen

    Citation: BMC Nephrology 2018 19:117

    Published on:

  43. Content type: Research article

    Chronic kidney disease of unknown origin (CKDu) in Sri Lanka is grouped with several other epidemics of similar nature across the world as Chronic Interstitial Nephritis in Agricultural Communities (CINAC). In...

    Authors: S. B. Agampodi, G. S. Amarasinghe, P. G. C. R. Naotunna, C. S. Jayasumana and S. H. Siribaddana

    Citation: BMC Nephrology 2018 19:115

    Published on:

  44. Content type: Research article

    Analyzing the relationships between biomarkers representing distinct pathophysiologic pathways and microalbuminuria (MA) can strengthen the identifying ability for renal damage and illuminate previously unreco...

    Authors: Shihui Fu, Yi Guo, Zhao Zhang, Leiming Luo and Ping Ye

    Citation: BMC Nephrology 2018 19:93

    Published on:

2017 Journal Metrics