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Epidemiology and Health Outcomes

Section edited by Bernard Jaar and Deputy Section Editor Laura Plantinga

The Epidemiology and Health Outcomes section considers manuscripts describing epidemiological studies relating to the field of nephrology. The section also considers systematic reviews and meta-analyses. Both qualitative and quantitative studies discussing health outcomes research and outcome measures are also considered by this section. Research related to clinical practice guidelines should be directed to the dedicated Guidelines and Policy section.

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  1. Multiple solutes are retained in uremia, but it is currently unclear which solutes are toxic. Small studies suggest that protein-bound solutes, such as p-cresol sulfate and indoxyl sulfate and intracellular so...

    Authors: Michal L Melamed, Laura Plantinga, Tariq Shafi, Rulan Parekh, Timothy W Meyer, Thomas H Hostetter, Josef Coresh and Neil R Powe

    Citation: BMC Nephrology 2013 14:134

    Content type: Research article

    Published on:

  2. The number of elderly (≥75 years) patients with end-stage renal disease (ESRD) has increased markedly, including in the Limousin region, which has the oldest population in France. We retrospectively compared o...

    Authors: Florence Glaudet, Carine Hottelart, Julien Allard, Vincent Allot, Frédérique Bocquentin, Rémy Boudet, Béatrice Champtiaux, Jean Pierre Charmes, Monica Ciobotaru, Zara Dickson, Marie Essig, Philippe Honoré, Céline Lacour, Christian Lagarde, Maria Manescu, Pierre Peyronnet…

    Citation: BMC Nephrology 2013 14:131

    Content type: Research article

    Published on:

  3. Diabetic nephropathy is a growing clinical problem, and the cause for >40% of incident ESRD cases. Unfortunately, few modifiable risk factors are known. The objective is to examine if albuminuria and history o...

    Authors: Douglas Gunzler, Anthony J Bleyer, Robert L Thomas, Alicia O’Brien, Gregory B Russell, Abdus Sattar, Sudha K Iyengar, Charles Thomas, John R Sedor and Jeffrey R Schelling

    Citation: BMC Nephrology 2013 14:124

    Content type: Research article

    Published on:

  4. Canada’s pandemic H1N1 influenza A (pH1N1) outbreak led to a high burden of critical illness. Our objective was to describe the incidence of AKI (acute kidney injury) in these patients and risk factors for AKI...

    Authors: Sean M Bagshaw, Manish M Sood, Jennifer Long, Robert A Fowler and Neill KJ Adhikari

    Citation: BMC Nephrology 2013 14:123

    Content type: Research article

    Published on:

  5. The Canadian Study of Prediction of Death, Dialysis and Interim Cardiovascular Events (CanPREDDICT) is a large, prospective, pan-Canadian, cohort study designed to improve our understanding of determinants of ...

    Authors: Adeera Levin, Claudio Rigatto, Barrett Brendan, François Madore, Norman Muirhead, Daniel Holmes, Catherine M Clase, Mila Tang and Ognjenka Djurdjev

    Citation: BMC Nephrology 2013 14:121

    Content type: Study protocol

    Published on:

  6. Group A streptococcus (GAS) is an etiological agent for the immune mediated sequela post streptococcal glomerulonephritis (PSGN). In some populations PSGN is recognized as a risk factor for chronic kidney dise...

    Authors: Mohan Ganesh Karmarkar, Gouri Pandharinath Hule, Niwrutti Khandu Hase, Preeti Rajeev Mehta, Scott Robert Walter and Kadaba Srinivasa Sriprakash

    Citation: BMC Nephrology 2013 14:101

    Content type: Research article

    Published on:

  7. Recent trends in parathyroidectomy rates are not known. Our objective was to investigate the trend in parathyroidectomy rates between 2001 and 2010, and to evaluate if the availability and reimbursement of cin...

    Authors: Jean-Philippe Lafrance, Héloïse Cardinal, Martine Leblanc, François Madore, Vincent Pichette, Louise Roy and Jacques Le Lorier

    Citation: BMC Nephrology 2013 14:100

    Content type: Research article

    Published on:

  8. Current data describing the epidemiology of acute kidney injury (AKI) following repair of ruptured abdominal aortic aneurysm (rAAA) are limited and long-term outcomes are largely unknown. Our objectives were t...

    Authors: Ilana Kopolovic, Kim Simmonds, Shelley Duggan, Mark Ewanchuk, Daniel E Stollery and Sean M Bagshaw

    Citation: BMC Nephrology 2013 14:99

    Content type: Research article

    Published on:

  9. Chronic kidney disease (CKD) affects up to 16% of the adult population and is associated with significant morbidity and mortality. People at highest risk from progressive CKD are defined by a sustained decline...

    Authors: Stephanie Stringer, Praveen Sharma, Mary Dutton, Mark Jesky, Khai Ng, Okdeep Kaur, Iain Chapple, Thomas Dietrich, Charles Ferro and Paul Cockwell

    Citation: BMC Nephrology 2013 14:95

    Content type: Study protocol

    Published on:

  10. People with end-stage kidney disease treated with dialysis experience high rates of premature death that are at least 30-fold that of the general population, and have markedly impaired quality of life. Despite...

    Authors: Giovanni FM Strippoli, Suetonia C Palmer, Marinella Ruospo, Patrizia Natale, Valeria Saglimbene, Jonathan C Craig, Fabio Pellegrini, Massimo Petruzzi, Michele De Benedittis, Pauline Ford, David W Johnson, Eduardo Celia, Ruben Gelfman, Miguel R Leal, Marietta Torok, Paul Stroumza…

    Citation: BMC Nephrology 2013 14:90

    Content type: Study protocol

    Published on:

  11. Chronic kidney disease (CKD) is an emerging public health problem worldwide. Previous studies have shown an association between blood pressure (BP) and CKD. However, it is not clear if there are ethnic differe...

    Authors: Charumathi Sabanayagam, Boon Wee Teo, E Shyong Tai, Tazeen H Jafar and Tien Yin Wong

    Citation: BMC Nephrology 2013 14:86

    Content type: Research article

    Published on:

  12. Large, population-based administrative healthcare databases can be used to identify patients with chronic kidney disease (CKD) when serum creatinine laboratory results are unavailable. We examined the validity...

    Authors: Jamie L Fleet, Stephanie N Dixon, Salimah Z Shariff, Robert R Quinn, Danielle M Nash, Ziv Harel and Amit X Garg

    Citation: BMC Nephrology 2013 14:81

    Content type: Research article

    Published on:

  13. Population-based data on the burden of chronic kidney disease (CKD) in sub-Saharan Africa is still very limited. We assessed the prevalence and determinants of CKD, and evaluated the concordance of commonly ad...

    Authors: Tandi E Matsha, Yandiswa Y Yako, Megan A Rensburg, Mogamat S Hassan, Andre P Kengne and Rajiv T Erasmus

    Citation: BMC Nephrology 2013 14:75

    Content type: Research article

    Published on:

  14. Chronic kidney disease (CKD) is a major issue in public health. Its prevalence has been calculated using estimation of glomerular filtration rate (GFR) by the creatinine-based equations developed in the Modifi...

    Authors: Pierre Delanaye, Etienne Cavalier, Olivier Moranne, Laurence Lutteri, Jean-Marie Krzesinski and Olivier Bruyère

    Citation: BMC Nephrology 2013 14:57

    Content type: Research article

    Published on:

  15. The Liu Comorbidity Index uses the United States Renal Data System (USRDS) to quantify comorbidity in chronic dialysis patients, capturing baseline comorbidities from days 91 through 270 after dialysis initiat...

    Authors: Sally K Rigler, James B Wetmore, Jonathan D Mahnken, Lei Dong, Edward F Ellerbeck and Theresa I Shireman

    Citation: BMC Nephrology 2013 14:51

    Content type: Research article

    Published on:

  16. Obesity and metabolic syndrome play causative roles in the increasing prevalence of proteinuria in the general population. However, in young adult women the clinical significance of incidentally discovered pro...

    Authors: Jwa-Kyung Kim, Young-Su Ju, Sung Jin Moon, Young Rim Song, Hyung Jik Kim and Sung Gyun Kim

    Citation: BMC Nephrology 2013 14:45

    Content type: Research article

    Published on:

  17. Nephrotic syndrome is one of the most commonly diagnosed kidney diseases in childhood and its progressive forms can lead to chronic kidney disease (CKD) and/or end-stage renal disease (ESRD). There have been f...

    Authors: Neesha Hussain, J Anastasia Zello, Jovanka Vasilevska-Ristovska, Tonny M Banh, Viral P Patel, Pranali Patel, Christopher D Battiston, Diane Hebert, Christoph P B Licht, Tino D Piscione and Rulan S Parekh

    Citation: BMC Nephrology 2013 14:25

    Content type: Study protocol

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  18. Evidence is lacking to inform providers’ and patients’ decisions about many common treatment strategies for patients with end stage renal disease (ESRD).

    Authors: L Ebony Boulware, Navdeep Tangri, Patti L Ephraim, Julia J Scialla, Stephen M Sozio, Deidra C Crews, Tariq Shafi, Dana C Miskulin, Jiannong Liu, Wendy St Peter, Bernard G Jaar, Albert W Wu, Neil R Powe, Sankar D Navaneethan and Karen Bandeen-Roche

    Citation: BMC Nephrology 2012 13:167

    Content type: Study protocol

    Published on:

COVID-19 Announcement

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time. Thank you.

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