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Hypertension, Hemodynamics and Vascular Regulation

The Hypertension, Hemodynamics and Vascular Regulation section considers both interventional and non-interventional clinical research studies, including controlled trials, case control studies, and basic experimental research. This section does not consider large epidemiological studies, or case reports. Systematic reviews and meta-analyses should be directed to the Epidemiology and Health Outcomes section.

  1. Perfusion deficits likely play an important role in the development of renal dysfunction in sepsis. Renal denervation may improve kidney perfusion and metabolism.

    Authors: Emiel Hendrik Post, Fuhong Su, Koji Hosokawa, Fabio Silvio Taccone, Antoine Herpain, Jacques Creteur, Daniel De Backer and Jean-Louis Vincent

    Citation: BMC Nephrology 2017 18:182

    Content type: Research article

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  2. The pathological condition of chronic kidney disease may not be adequately recapitulated in immunocompromised mice due to the lack of T-cells, which are important for the development of hypertension and renal ...

    Authors: Nynke R. Oosterhuis, Diana A. Papazova, Hendrik Gremmels, Jaap A. Joles and Marianne C. Verhaar

    Citation: BMC Nephrology 2017 18:153

    Content type: Research article

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  3. Ischemia and reperfusion (I/R) is one of the major causes of acute kidney injury (AKI). Citrate reduces hypoxia-induced mitochondrial energetic deficits in isolated proximal tubules. Moreover, citrate anticoag...

    Authors: Anja Bienholz, Jonas Reis, Pinar Sanli, Herbert de Groot, Frank Petrat, Hana Guberina, Benjamin Wilde, Oliver Witzke, Fuat H. Saner, Andreas Kribben, Joel M. Weinberg and Thorsten Feldkamp

    Citation: BMC Nephrology 2017 18:130

    Content type: Research article

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  4. Stroke and low heart rate variability (HRV) are both associated with an unfavorable prognosis in hemodialysis patients. The relationship between stroke and changes in HRV during hemodialysis remains unclear.

    Authors: Jiun-Chi Huang, Chien-Fu Chen, Chia-Chu Chang, Szu-Chia Chen, Ming-Chia Hsieh, Yao-Peng Hsieh and Hung-Chun Chen

    Citation: BMC Nephrology 2017 18:90

    Content type: Research article

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  5. Hemodialysis (HD) with ultrafiltration (UF) in chronic renal replacement therapy is associated with hemodynamic instability, morbidity and mortality. Sublingual Sidestream Dark Field (SDF) imaging during HD re...

    Authors: Gerke Veenstra, Andrius Pranskunas, Inga Skarupskiene, Vidas Pilvinis, Marc H. Hemmelder, Can Ince and E. Christiaan Boerma

    Citation: BMC Nephrology 2017 18:71

    Content type: Research article

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  6. In recent years, early Endothelial Progenitor Cells (eEPCs) have been proven as effective tool in murine ischemic AKI and in diabetic nephropathy. The mechanisms of eEPC-mediated vasoprotection have been eluci...

    Authors: D. Patschan, K. Schwarze, B. Tampe, M. Zeisberg, S. Patschan and G. A. Müller

    Citation: BMC Nephrology 2017 18:53

    Content type: Research article

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  7. Acute Kidney injury (AKI) is common and increases mortality in the intensive care unit (ICU). We carried out this study to explore whether fluid overload is an independent risk factor for AKI.

    Authors: Nawal Salahuddin, Mustafa Sammani, Ammar Hamdan, Mini Joseph, Yasir Al-Nemary, Rawan Alquaiz, Ranim Dahli and Khalid Maghrabi

    Citation: BMC Nephrology 2017 18:45

    Content type: Research article

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  8. Patients with chronic kidney disease have a markedly increased cardiovascular mortality compared with the general population. Long chain n-3 polyunsaturated fatty acids have been suggested to possess cardioprotec...

    Authors: Morten Borg, My Svensson, Johan V. Povlsen, Erik B. Schmidt, Christian Aalkjær, Jeppe H. Christensen and Per Ivarsen

    Citation: BMC Nephrology 2016 17:184

    Content type: Research article

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  9. To investigate the combined use of intravoxel incoherent motion (IVIM) diffusion-weighted (DW) and blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) to assess rat renal function using a 1.5T...

    Authors: Neil P. Jerome, Jessica K. R. Boult, Matthew R. Orton, James d’Arcy, David J. Collins, Martin O. Leach, Dow-Mu Koh and Simon P. Robinson

    Citation: BMC Nephrology 2016 17:142

    Content type: Research article

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  10. Fluid overload is frequently found in acute kidney injury patients in critical care units. Recent studies have shown the relationship of fluid overload with adverse outcomes; hence, manage and optimization of ...

    Authors: Rolando Claure-Del Granado and Ravindra L. Mehta

    Citation: BMC Nephrology 2016 17:109

    Content type: Debate

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  11. Two-dimensional measures of vascular architecture provide incomplete information about vascular structure. This study applied a novel rigorous method for 3D microCT-based analysis of total and cortical renal v...

    Authors: Daniel S. Perrien, Mohamed A. Saleh, Keiko Takahashi, Meena S. Madhur, David G. Harrison, Raymond C. Harris and Takamune Takahashi

    Citation: BMC Nephrology 2016 17:24

    Content type: Technical advance

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  12. Recent studies suggest a causal role for increased plasma uric acid in the progression of chronic renal insufficiency (CRI). However, uric acid also functions as an antioxidant with possible beneficial effects.

    Authors: Venla Kurra, Tuija Vehmas, Arttu Eräranta, Jarkko Jokihaara, Päivi Pirttiniemi, Heikki Ruskoaho, Heikki Tokola, Onni Niemelä, Jukka Mustonen and Ilkka Pörsti

    Citation: BMC Nephrology 2015 16:35

    Content type: Research article

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  13. The purpose of this study was to evaluate the feasibility of utilizing an in-vitro, closed loop hemodialysis system as a method to assess drug clearance. Secondarily, this study tested the influence of variables ...

    Authors: Soo Min Jang, Katie E Cardone, Thomas D Nolin, Darius L Mason and Darren W Grabe

    Citation: BMC Nephrology 2014 15:204

    Content type: Research article

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  14. Tolvaptan is a selective vasopressin receptor antagonist (V2R) that increases free water excretion. We wanted to test the hypotheses that tolvaptan changes both renal handling of water and sodium and systemic ...

    Authors: Safa Al Therwani, Frank Holden Mose, Janni Majgaard Jensen, Jesper Nørgaard Bech and Erling Bjerregaard Pedersen

    Citation: BMC Nephrology 2014 15:100

    Content type: Research article

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  15. Measurement of renal perfusion is a crucial part of measuring kidney function. Arterial spin labelling magnetic resonance imaging (ASL MRI) is a non-invasive method of measuring renal perfusion using magnetise...

    Authors: Keith A Gillis, Christie McComb, John E Foster, Alison HM Taylor, Rajan K Patel, Scott TW Morris, Alan G Jardine, Markus P Schneider, Giles H Roditi, Christian Delles and Patrick B Mark

    Citation: BMC Nephrology 2014 15:23

    Content type: Research article

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  16. The ambulatory arterial stiffness index (AASI) can be used to predict cardiovascular morbidity and mortality in hypertensive patients. However, data on AASI in Chinese patients with chronic kidney disease (CKD...

    Authors: Cheng Wang, Jun Zhang, Cui-Cui Li, Wen-Yu Gong, Xun Liu, Zeng-Chun Ye, Hui Peng and Tan-Qi Lou

    Citation: BMC Nephrology 2013 14:257

    Content type: Research article

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  17. Acute kidney injury (AKI) severely worsens prognosis of hospitalized patients. Early Endothelial Outgrowth Cells act protective in murine acute ischemic renal failure and renoprotective actions of eEOCs have b...

    Authors: Daniel Patschan, Jörg Rinneburger, Nazif Idrizi, Rico Backhaus, Katrin Schwarze, Elvira Henze, Susann Patschan and Gerhard A Müller

    Citation: BMC Nephrology 2013 14:227

    Content type: Research article

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  18. Among African-Americans adults, arterial hypertension is both more prevalent and associated with more complications than among white adults. Hypertension is also epidemic among black adults in sub-Saharan Afri...

    Authors: Robert N Peck, Luke R Smart, Rita Beier, Anthony C Liwa, Heiner Grosskurth, Daniel W Fitzgerald and Bernhard MW Schmidt

    Citation: BMC Nephrology 2013 14:201

    Content type: Research article

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  19. Chronic kidney disease (CKD) and coronary artery disease (CAD) are independently associated with increased vascular stiffness. We examined whether renal function contributes to vascular stiffness independently...

    Authors: Sabrina H Rossi, Emily P McQuarrie, William H Miller, Ruth M Mackenzie, Jane A Dymott, María U Moreno, Chiara Taurino, Ashley M Miller, Ulf Neisius, Geoffrey A Berg, Zivile Valuckiene, Jonathan A Hannay, Anna F Dominiczak and Christian Delles

    Citation: BMC Nephrology 2013 14:173

    Content type: Research article

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  20. Vitamin D receptor activators reduce albuminuria, and may improve survival in chronic kidney disease (CKD). Animal studies suggest that these pleiotropic effects of vitamin D may be mediated by suppression of ...

    Authors: Thomas Larsen, Frank H Mose, Jesper N Bech and Erling B Pedersen

    Citation: BMC Nephrology 2013 14:163

    Content type: Research article

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  21. Process of accelerated atherosclerosis specific for uremia increases cardiovascular risk in patients with chronic kidney disease (CKD) and may be influenced by the different structure of arteries. The study as...

    Authors: Przemysław Pencak, Beata Czerwieńska, Rafał Ficek, Katarzyna Wyskida, Agata Kujawa-Szewieczek, Magdalena Olszanecka-Glinianowicz, Andrzej Więcek and Jerzy Chudek

    Citation: BMC Nephrology 2013 14:10

    Content type: Research article

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As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time. Thank you.

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