Pediatric Nephrology

Section edited by Jerome Harambat

The Pediatric section considers both interventional and non-interventional clinical research studies, including controlled trials and case control studies. This section does not consider basic experimental research, large epidemiological studies, or case reports. Systematic reviews and meta-analyses should be directed to the ‘Epidemiology and Health Outcomes’ section, and Case reports should be directed to our dedicated ‘Case Report’ section

  1. Research article

    The impact of IgM deposits on the outcome of Nephrotic syndrome in children

    The significance of IgM deposits in glomerular mesangium has been controversial since they were first described due to the variations in the both the definitions used and described impact on clinical outcome. ...

    Sandra Juozapaite, Rimante Cerkauskiene, Arvydas Laurinavicius and Augustina Jankauskiene

    BMC Nephrology 2017 18:260

    Published on: 3 August 2017

  2. Research article

    Worldwide view of nephropathic cystinosis: results from a survey from 30 countries

    Nephropathic cystinosis is a rare inherited metabolic disorder leading to progressive renal failure and extra-renal comorbidity. The prognosis relies on early adherence to cysteamine treatment and symptomatic ...

    Aurélia Bertholet-Thomas, Julien Berthiller, Velibor Tasic, Behrouz Kassai, Hasan Otukesh, Marcella Greco, Jochen Ehrich, Rejane de Paula Bernardes, Georges Deschênes, Sally-Ann Hulton, Michel Fischbach, Kenza Soulami, Bassam Saeed, Ehsan Valavi, Carlos Jose Cobenas, Bülent Hacihamdioglu…

    BMC Nephrology 2017 18:210

    Published on: 3 July 2017

  3. Research article

    Deviations from the expected relationship between serum FGF23 and other markers in children with CKD: a cross-sectional study

    High levels of fibroblast growth factor-23 (FGF23) are associated with mortality. In chronic kidney disease (CKD), FGF23 levels rise as renal function declines. We analyzed the contribution of laboratory value...

    Daisy Liu, Ana Catalina Alvarez-Elías, Brooke Wile, Vladimir Belostotsky and Guido Filler

    BMC Nephrology 2017 18:204

    Published on: 28 June 2017

  4. Research article

    Approach to growth hormone therapy in children with chronic kidney disease varies across North America: the Midwest Pediatric Nephrology Consortium report

    Growth impairment remains common in children with chronic kidney disease (CKD). Available literature indicates low level of recombinant human growth hormone (rhGH) utilization in short children with CKD. Despi...

    Oleh M. Akchurin, Amy J. Kogon, Juhi Kumar, Christine B. Sethna, Hoda T. Hammad, Paul J. Christos, John D. Mahan, Larry A. Greenbaum and Robert Woroniecki

    BMC Nephrology 2017 18:181

    Published on: 30 May 2017

  5. Research article

    Accuracy of cystatin C in prediction of acute kidney injury in children; serum or urine levels: which one works better? A systematic review and meta-analysis

    There is still an ongoing discussion on the prognostic value of cystatin C in assessment of kidney function. Accordingly, the present study aimed to conduct a meta-analysis to provide evidence for the prognost...

    Babak Nakhjavan-Shahraki, Mahmoud Yousefifard, Neamatollah Ataei, Masoud Baikpour, Fatemeh Ataei, Behnaz Bazargani, Arash Abbasi, Parisa Ghelichkhani, Faezeh Javidilarijani and Mostafa Hosseini

    BMC Nephrology 2017 18:120

    Published on: 3 April 2017

  6. Research article

    Turkish pediatric atypical hemolytic uremic syndrome registry: initial analysis of 146 patients

    Atypical hemolytic uremic syndrome (aHUS) is a devastating disease with significant morbidity and mortality. Its genetic heterogeneity impacts its clinical presentation, progress, and outcome, and there is no ...

    Nesrin Besbas, Bora Gulhan, Oguz Soylemezoglu, Z. Birsin Ozcakar, Emine Korkmaz, Mutlu Hayran and Fatih Ozaltin

    BMC Nephrology 2017 18:6

    Published on: 5 January 2017

  7. Research article

    Serum cystatin is a useful marker for the diagnosis of acute kidney injury in critically ill children: prospective cohort study

    Acute kidney injury (AKI) has been associated with high morbidity and mortality rates among critically ill children. Cystatin C is a protease inhibitor, and studies have shown that it is a promising marker for...

    Osama Y. Safdar, Mohammed Shalaby, Norah Khathlan, Bassem Elattal, Mohammed Bin Joubah, Esraa Bukahri, Mafaza Saber, Arwa Alahadal, Hala Aljariry, Safaa Gasim, Afnan Hadadi, Abdullah Alqahtani, Roaa Awleyakhan and Jameela A. Kari

    BMC Nephrology 2016 17:130

    Published on: 13 September 2016

  8. Research article

    The global pediatric nephrology workforce: a survey of the International Pediatric Nephrology Association

    The global pediatric nephrology workforce is poorly characterized. The objectives of our study were to assess pediatric nephrologists’ perceptions of the adequacy of the pediatric nephrology workforce, and und...

    Dorey Glenn, Sophie Ocegueda, Meaghan Nazareth, Yi Zhong, Adam Weinstein, William Primack, Pierre Cochat and Maria Ferris

    BMC Nephrology 2016 17:83

    Published on: 15 July 2016

  9. Study protocol

    KNOW-Ped CKD (KoreaN cohort study for outcomes in patients with pediatric CKD): Design and methods

    The global prevalence of chronic kidney disease (CKD) is increasing. In children, CKD exhibits unique etiologies and can have serious impacts on children’s growth and development. Therefore, an aggressive appr...

    Hee Gyung Kang, Hyun Jin Choi, Kyung Hee Han, Seong Heon Kim, Hee Yeon Cho, Min Hyun Cho, Jae Il Shin, Joo Hoon Lee, Joongyub Lee, Kook Hwan Oh, Young Seo Park, Hae Il Cheong, Curie Ahn and Il-Soo Ha

    BMC Nephrology 2016 17:35

    Published on: 25 March 2016

  10. Study protocol

    Design and methods of the NiCK study: neurocognitive assessment and magnetic resonance imaging analysis of children and young adults with chronic kidney disease

    Chronic kidney disease is strongly linked to neurocognitive deficits in adults and children, but the pathophysiologic processes leading to these deficits remain poorly understood. The NiCK study (Neurocognitiv...

    Erum A Hartung, Nina Laney, Ji Young Kim, Rebecca L Ruebner, John A Detre, Hua-Shan Liu, Christos Davatzikos, Guray Erus, Jimit J Doshi, Robert T Schultz, John D Herrington, Abbas F Jawad, Divya G Moodalbail, Ruben C Gur, Allison M Port, Jerilynn Radcliffe…

    BMC Nephrology 2015 16:66

    Published on: 30 April 2015

  11. Study protocol

    Rationale, design and objectives of ARegPKD, a European ARPKD registry study

    Autosomal recessive polycystic kidney disease (ARPKD) is a rare but frequently severe disorder that is typically characterized by cystic kidneys and congenital hepatic fibrosis but displays pronounced phenotyp...

    Kathrin Ebner, Markus Feldkoetter, Gema Ariceta, Carsten Bergmann, Reinhard Buettner, Anke Doyon, Ali Duzova, Heike Goebel, Dieter Haffner, Barbara Hero, Bernd Hoppe, Thomas Illig, Augustina Jankauskiene, Norman Klopp, Jens König, Mieczyslaw Litwin…

    BMC Nephrology 2015 16:22

    Published on: 18 February 2015

BMC Nephrology is affiliated with The Renal Association