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Pre-dialysis care and dialysis

Section edited by Giorgina Piccoli 

The Pre-dialysis Care and Dialysis section considers clinical research relating to the care of patients both before and during dialysis and their post-dialysis outcomes. Articles may describe interventional and non-interventional studies as well as qualitative studies. Systematic reviews, meta-analyses and large epidemiological studies should be directed to the Epidemiology and Health Outcomes section. This section does not consider case reports and these should be directed to the dedicated Case Reports section.

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  1. The purse-string suture has been widely used for bleeding control after percutaneous interventions through arteriovenous fistula (AVF) and graft (AVG), and it requires suture removal the next day. This study a...

    Authors: Qiquan Lai, Hui Zhang, Bo Chen, Xuejing Gao, Ling Chen, Bo Tu, Baifei Li, Bo Hu, Fan He, Yong Xu and Ziming Wan

    Citation: BMC Nephrology 2020 21:112

    Content type: Research article

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  2. A randomized trial of a pedometer-based intervention with weekly activity goals led to a modest increase in step count among dialysis patients. In a secondary analysis, we investigated the effect of this inter...

    Authors: Anoop Sheshadri, Piyawan Kittiskulnam, Jennifer C. Lai and Kirsten L. Johansen

    Citation: BMC Nephrology 2020 21:100

    Content type: Research article

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  3. Acute kidney injury (AKI) is a common complication among human immunodeficiency virus (HIV)-infected patients resulting in increased morbidity and mortality. Continuous renal replacement therapy (CRRT) is a us...

    Authors: Hebing Guo, Jingyuan Liu, Lin Pu, Jingjing Hao, Ningning Yin, Yufeng Liu, Haofeng Xiong and Ang Li

    Citation: BMC Nephrology 2020 21:95

    Content type: Research article

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  4. Nutritional factors are associated with high mortality and morbidity in dialysis patients, and protein-energy wasting is regarded as an important one. The modality of dialysis may affect patients’ dietary beha...

    Authors: Seon-Mi Kim, Byung Chin Kang, Hyun-Jung Kim, Min-Sook Kyung, Hyung Jung Oh, Jung-Hyun Kim, Oran Kwon and Dong-Ryeol Ryu

    Citation: BMC Nephrology 2020 21:91

    Content type: Research article

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  5. Vascular calcification (VC) is a risk factor for cardiovascular disease in end-stage renal disease (ESRD) patients undergoing maintenance haemodialysis (MHD). However, evidence is still insufficient about the ...

    Authors: Sung Keun Park, Won Joong Kim, Hyun Jin Kim, Hae Won Kim, Beom Kim, Hong Joo Lee, So-Young Lee, Yu Ho Lee, Dong-Jin Kim, Kyung-Hwan Jeong, Ju-Young Moon, Sang-Ho Lee, Shin Young Ahn, Gang Jee Ko, Jae-Hong Ryoo and Dong-Young Lee

    Citation: BMC Nephrology 2020 21:86

    Content type: Research article

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  6. Chronic kidney disease (CKD) is increasing worldwide, and the majority of the CKD burden is in low- and middle-income countries (LMICs). However, there is wide variability in global access to kidney care thera...

    Authors: David Flood, Katharine Wilcox, Andrea Aguilar Ferro, Carlos Mendoza Montano, Joaquin Barnoya, Pablo Garcia, Randall Lou-Meda, Peter Rohloff and Anita Chary

    Citation: BMC Nephrology 2020 21:71

    Content type: Research article

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  7. Calcific Uremic Arteriolopathy (CUA) is a rare disease, causing painful skin ulcers in patients with end stage renal disease. Recommendations for CUA management and treatment are lacking.

    Authors: Raphaël Gaisne, Morgane Péré, Victorio Menoyo, Maryvonne Hourmant and David Larmet-Burgeot

    Citation: BMC Nephrology 2020 21:63

    Content type: Research article

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  9. This study aimed to determine the lifetime cost-effectiveness of first-line dialysis modalities for end-stage renal disease (ESRD) patients under the “Peritoneal Dialysis First” policy.

    Authors: Carlos K. H. Wong, Julie Chen, Samuel K. S. Fung, Maggie Mok, Yuk lun Cheng, Irene Kong, Wai Kei Lo, Sing Leung Lui, T. M. Chan and Cindy L. K. Lam

    Citation: BMC Nephrology 2020 21:42

    Content type: Research article

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  10. Older patients on dialysis may not have optimal outcomes, particularly with regards to quality of life. Existing research is focused mainly on survival, with limited information about other outcomes. Such info...

    Authors: Rajesh Raj, Bridget Brown, Kiran Ahuja, Mai Frandsen and Matthew Jose

    Citation: BMC Nephrology 2020 21:28

    Content type: Research article

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  11. Chronic kidney disease (CKD) disease affects gut flora by causing dysbiosis and lead to systemic inflammatory conditions. Here, we provide intestinal flora changes of CKD patients undertook different hemodialy...

    Authors: Jianguang Hu, Xiaoshi Zhong, Jing Yan, Daoyuan Zhou, Danping Qin, Xiao Xiao, Yuanyuan Zheng and Yan Liu

    Citation: BMC Nephrology 2020 21:12

    Content type: Research article

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  12. The impact of length of hospital stay on activities of daily living (ADLs) has not specifically been investigated among dialysis patients. Therefore, we attempt to verify the association between the length of ...

    Authors: Tsukasa Kamitani, Shingo Fukuma, Sayaka Shimizu, Tadao Akizawa and Shunichi Fukuhara

    Citation: BMC Nephrology 2020 21:9

    Content type: Research article

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  13. Impaired physical function due to muscle weakness and exercise intolerance reduces the ability to perform activities of daily living in patients with end-stage kidney disease, and by consequence, Health-Relate...

    Authors: Karsten Vanden Wyngaert, Amaryllis H. Van Craenenbroeck, Sunny Eloot, Patrick Calders, Bert Celie, Els Holvoet and Wim Van Biesen

    Citation: BMC Nephrology 2020 21:7

    Content type: Research article

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  14. Online haemodiafiltration (OL-HDF) may improve middle molecular clearance in contrast to conventional haemodialysis (HD). However, OL-HDF requires higher convective flows and cannot sufficiently remove large m...

    Authors: Tae Hoon Kim, Seok-hyung Kim, Tae Yeon Kim, Hae Yeul Park, Kwon Soo Jung, Moon Hyoung Lee, Jong Hyun Jhee, Jung Eun Lee, Hoon Young Choi and Hyeong Cheon Park

    Citation: BMC Nephrology 2019 21:2

    Content type: Research article

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  15. Patients on home hemodialysis (HHD) exhibit superior survival compared with patients on institutional hemodialysis (IHD) and peritoneal dialysis (PD). There is a sparsity of reports comparing morbidity between...

    Authors: Helena Rydell, Kerstin Ivarsson, Martin Almquist, Naomi Clyne and Mårten Segelmark

    Citation: BMC Nephrology 2019 20:480

    Content type: Research article

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  16. Physical activity (PA) is exceptionally low amongst the haemodialysis (HD) population, and physical inactivity is a powerful predictor of mortality, making it a prime focus for intervention. Objective measurem...

    Authors: Hannah M. L. Young, Mark W. Orme, Yan Song, Maurice Dungey, James O. Burton, Alice C. Smith and Sally J. Singh

    Citation: BMC Nephrology 2019 20:450

    Content type: Research article

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  17. Arteriovenous fistula (AVF) is the vascular access of choice for patients on hemodialysis. Recent evidence suggests that AVF creation may slow estimated glomerular filtration rate (eGFR) decline. The study obj...

    Authors: Valérie Bénard, Maude Pichette, Jean-Philippe Lafrance, Naoual Elftouh, Vincent Pichette, Louis-Philippe Laurin and Annie-Claire Nadeau-Fredette

    Citation: BMC Nephrology 2019 20:420

    Content type: Research article

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  18. Nonadherence to medications by patients requiring hemodialysis (HD) leads to unfavorable clinical outcomes. Limited data exist to demonstrate the effect of incorporating patient-centered interventions using co...

    Authors: Sherine Ismail, Abrar Al-Subhi, Eman Youssif, Medhat Ahmed, Abdullah Almalki, Diane L. Seger, Andrew C. Seger and Earl Cook

    Citation: BMC Nephrology 2019 20:408

    Content type: Research article

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  19. Patients with chronic kidney diseases (CKD) on haemodialysis (HD) have high morbidity and mortality rates, which are also due to the inherent risks associated with nephropathy. Non-adherence (NA) to the differ...

    Authors: Lianna G. G. Dantas, Mário de Seixas Rocha, José Andrade Moura Junior, Edson Luiz Paschoalin, Sandra R. K. P. Paschoalin and Constança M. Sampaio Cruz

    Citation: BMC Nephrology 2019 20:402

    Content type: Research article

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  20. Conservative management, an approach to treating end-stage kidney disease without dialysis, while generally associated with shorter life expectancy than treatment with dialysis, is associated with fewer hospit...

    Authors: Melissa W. Wachterman, Tarikwa Leveille, Nancy L. Keating, Steven R. Simon, Sushrut S. Waikar and Barbara Bokhour

    Citation: BMC Nephrology 2019 20:385

    Content type: Research article

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  22. More than 6200 End Stage Renal Disease patients in the Netherlands are dependent on dialysis, either performed at home or in a dialysis centre. Visiting a dialysis centre three times a week is considered a lar...

    Authors: A. van Eck van der Sluijs, A. A. Bonenkamp, F. W. Dekker, A. C. Abrahams and B. C. van Jaarsveld

    Citation: BMC Nephrology 2019 20:361

    Content type: Study protocol

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  23. Pulsatility is an important property of hemodialysis arteriovenous fistulas (AVF) and can be perceived by the fingers as a gradual decrease in strength downstream from the anastomosis along the main trunk of t...

    Authors: Matt Chiung-Yu Chen, Mei-Jui Weng, Misoso Yi-Wen Wu, Yi-Chun Liu and Wen-Che Chi

    Citation: BMC Nephrology 2019 20:356

    Content type: Research article

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  24. Intradialytic blood pressure (BP) measurement is currently the main parameter used for monitoring hemodynamics during hemodialysis (HD). Since BP is dependent on cardiac output and total peripheral resistance,...

    Authors: Keren Doenyas-Barak, Marcia H. F. G. de Abreu, Lucas E. Borges, Helcio A. Tavares Filho, Feng Yunlin, Zou Yurong, Nathan W. Levin, Allen M. Kaufman, Shay Efrati, David Pereg, Ilya Litovchik, Shmuel Fuchs and Sa’ar Minha

    Citation: BMC Nephrology 2019 20:347

    Content type: Research article

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  25. Patient-reported outcome measures (PROMs) are becoming increasingly important in healthcare. In nephrology, there is no agreement on which chronic kidney disease (CKD) symptom questionnaire to use. Therefore, ...

    Authors: Esmee M. van der Willik, Yvette Meuleman, Karen Prantl, Giel van Rijn, Willem Jan W. Bos, Frans J. van Ittersum, Hans A. J. Bart, Marc H. Hemmelder and Friedo W. Dekker

    Citation: BMC Nephrology 2019 20:344

    Content type: Research article

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  26. Patients treated with conventional hemodialysis have poor physical performance, explained by insufficient metabolic clearance and shortage of time by time-consuming dialysis. Nocturnal hemodialysis improves me...

    Authors: Manouk Dam, Peter J. M. Weijs, Frans J. van Ittersum and Brigit C. van Jaarsveld

    Citation: BMC Nephrology 2019 20:317

    Content type: Research article

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  27. Chromium is an essential trace metal that reduces oxidative stress and inflammation. In patients undergoing maintenance hemodialysis (MHD), a correlation among chromium exposure, inflammation, and malnutrition...

    Authors: Ching-Wei Hsu, Cheng-Hao Weng, Cheng-Chia Lee, Tzung-Hai Yen and Wen-Hung Huang

    Citation: BMC Nephrology 2019 20:302

    Content type: Research article

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  28. Haemodialysis is capable of prolonging life in patients with end stage renal disease, however this therapy comes with significant negative impact on quality of life. For patients requiring haemodialysis, the n...

    Authors: M. Field, A.Z Khawaja, J. Ellis, T. Nieto, J. Hodson and N. Inston

    Citation: BMC Nephrology 2019 20:299

    Content type: Research article

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  29. Short-term hemoglobin (Hb) variability related to volume status is observed in chronic kidney disease (CKD) patients receiving hemodialysis (HD). Given the lack of studies regarding outcomes according to the d...

    Authors: Soo Ya Bae, Jae Wan Jeon, Seong Hoon Kim, Chung Hee Baek, Jai Won Jang, Won Seok Yang, Soon Bae Kim, Su-Kil Park, Sang Koo Lee and Hyosang Kim

    Citation: BMC Nephrology 2019 20:295

    Content type: Research article

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  30. Although hemodialysis is a highly effective treatment for diffusive clearance of low molecular weight uremic toxins, its effect on circulating extracellular vesicles and submicron particles is less clear. The ...

    Authors: Marcel Ruzicka, Fengxia Xiao, Hussein Abujrad, Yasamin Al-Rewashdy, Vera A. Tang, Marc-André Langlois, Alexander Sorisky, Teik Chye Ooi and Dylan Burger

    Citation: BMC Nephrology 2019 20:294

    Content type: Research article

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  31. Readmission within 30 days of hospital discharge is common and costly among end-stage renal disease (ESRD) patients. Little is known about long-term outcomes after readmission. We estimated the association bet...

    Authors: Katherine H. Ross, Bernard G. Jaar, Janice P. Lea, Tahsin Masud, Rachel E. Patzer and Laura C. Plantinga

    Citation: BMC Nephrology 2019 20:285

    Content type: Research article

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  32. Despite well-publicized suggestions to utilize arteriovenous fistulae and grafts to initiate hemodialysis, too many patients in the United States start dialysis via central venous catheters despite their well-...

    Authors: Tanya T. Tang, Murray L. Levin, Shubhada N. Ahya, Khaled Boobes and Muhammad H. Hasan

    Citation: BMC Nephrology 2019 20:270

    Content type: Research article

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  33. Many older patients approaching end-stage kidney disease have to decide whether to go for dialysis or non-dialytic conservative care (CC). Shared decision-making is recommended to align the treatment plan with...

    Authors: Wouter R. Verberne, Wanda S. Konijn, Karen Prantl, Janneke Dijkers, Margriet T. Roskam, Johannes J. M. van Delden and Willem Jan W. Bos

    Citation: BMC Nephrology 2019 20:264

    Content type: Research article

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  34. Observational studies of hemodialysis patients treated thrice weekly have shown that serum and dialysate potassium and bicarbonate concentrations are associated with patient outcomes. The effect of more freque...

    Authors: John K. Leypoldt, Michael A. Kraus, Bertrand L. Jaber, Eric D. Weinhandl and Allan J. Collins

    Citation: BMC Nephrology 2019 20:252

    Content type: Research article

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  35. Globally 10% of the population worldwide are affected by chronic kidney disease (CKD), making it one of the most prevalent chronic diseases. Several studies have highlighted that the symptoms of CKD have a sig...

    Authors: Bushra Alshammari, Helen Noble, Helen McAneney and Peter O’Halloran

    Citation: BMC Nephrology 2019 20:250

    Content type: Study protocol

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  37. Many studies have evaluated the usefulness of creatinine- (eGFRcr) and cystatin C-based estimated glomerular filtration rate (eGFRcys) at specific time points in predicting renal outcome. This study compared t...

    Authors: Suhyun Kim, Subin Hwang, Hye Ryoun Jang, Insuk Sohn, Hyeon Seon Ahn, Hyung-Doo Park, Wooseong Huh, Dong-Chan Jin, Yoon-Goo Kim, Dae Joong Kim, Ha Young Oh and Jung Eun Lee

    Citation: BMC Nephrology 2019 20:214

    Content type: Research article

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  39. Due to rising vascular comorbidities of patients undergoing dialysis, the prevalence of permanent hemodialysis catheters as hemodialysis access is increasing. However, infection is a major complication of thes...

    Authors: Fani Delistefani, Manuel Wallbach, Gerhard A. Müller, Michael J. Koziolek and Clemens Grupp

    Citation: BMC Nephrology 2019 20:199

    Content type: Research article

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  40. Successful vascular access (VA) cannulation is integral to the delivery of adequate dialysis, highlighting the importance of ensuring the viability of arteriovenous access in hemodialysis (HD) patients. Missed...

    Authors: Linda L. Coventry, Jon M. Hosking, Doris T. Chan, Evelyn Coral, Wai H. Lim, Amanda Towell-Barnard, Diane E. Twigg and Claire M. Rickard

    Citation: BMC Nephrology 2019 20:197

    Content type: Research article

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  41. Thrombophilia due to protein C (PC) and protein S (PS) deficiencies is highly prevalent among patients with stage 5 chronic kidney disease and is reported to arise due to extracorporeal circulation during hemo...

    Authors: Mayuri Ichinose, Naru Sasagawa, Tetsuo Chiba, Katsuhide Toyama, Yuzo Kayamori and Dongchon Kang

    Citation: BMC Nephrology 2019 20:191

    Content type: Research article

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  42. Reduced muscle strength and physical performance are prevalent in patients of maintenance hemodialysis (MHD), and deleterious changes in these parameters are associated with increased mortality.

    Authors: Yoshifumi Moriyama, Masahiko Hara, Sae Aratani, Hideaki Ishikawa, Kenichi Kono and Masatake Tamaki

    Citation: BMC Nephrology 2019 20:172

    Content type: Research article

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  43. The putative benefits of cinacalcet therapy for management of secondary hyperparathyroidism (SHPT) are thought to be most manifested when patients are taking it consistently and as prescribed. Real-world descr...

    Authors: Douglas S. Fuller, David Hallett, Paul J. Dluzniewski, Bruno Fouqueray, Michel Jadoul, Hal Morgenstern, Friedrich K. Port, Francesca Tentori and Ronald L. Pisoni

    Citation: BMC Nephrology 2019 20:169

    Content type: Research article

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  44. Tunnelled dialysis catheter (TC) infections are a major health complication and are associated with increased antibiotic consumption, hospital stays, health costs and mortality. Experimental data provide evide...

    Authors: Julien Aniort, Aurélien Piraud, Mireille Adda, Bruno Perreira, Marc Bouiller, Jacques Fourcade, Abdallah Guerraoui, Emilie Kalbacher, Thierry Krumel, Hélène Leray Moragues, Damien Thibaudin, Carlos Gustavo Vela, Guillaume Vernin, Hugo Weclawiak, Lise Bernard, Anne Elisabeth Heng…

    Citation: BMC Nephrology 2019 20:149

    Content type: Study protocol

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  45. Despite an increasing number of older people commencing dialysis the impact of dialysis on their quality of life and survival, remains unclear. The Dialysis Outcomes in those aged over 65 years or older study ...

    Authors: Bronwen McNoe, John B. W. Schollum, Sarah Derrett, Mark R. Marshall, Andrew Henderson, Ari Samaranayaka and Robert J. Walker

    Citation: BMC Nephrology 2019 20:137

    Content type: Research article

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  46. Prolonged QT interval in hemodialysis patients may be associated with sudden cardiac death, however, few studies examined the longitudinal associations of modifiable factors such as serum and dialysate concent...

    Authors: Esther D. Kim, Jacqueline Watt, Larisa G. Tereshchenko, Bernard G. Jaar, Stephen M. Sozio, W. H. Linda Kao, Michelle M. Estrella and Rulan S. Parekh

    Citation: BMC Nephrology 2019 20:133

    Content type: Research article

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  47. The prevalence of chronic kidney disease (CKD) is increasing worldwide and in Africa. Health related quality of life (QOL) has become an essential outcome measure for patients with CKD and end stage renal dise...

    Authors: Elliot K. Tannor, Betty R. Norman, Kwame K. Adusei, Fred S. Sarfo, Mogamat R. Davids and George Bedu-Addo

    Citation: BMC Nephrology 2019 20:122

    Content type: Research article

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  48. Self-management education needs have not been assessed in patients with complex co-morbid conditions such as diabetes and chronic kidney disease (CKD). The objectives of this study were to 1) determine the sel...

    Authors: Edward Zimbudzi, Clement Lo, Peter G. Kerr and Sophia Zoungas

    Citation: BMC Nephrology 2019 20:113

    Content type: Research article

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