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Pre-dialysis care and dialysis

The Pre-dialysis Care and Dialysis section considers clinical research relating to the care of patients both before and during dialysis and their post-dialysis outcomes. Articles may describe interventional and non-interventional studies as well as qualitative studies. Systematic reviews, meta-analyses and large epidemiological studies should be directed to the Epidemiology and Health Outcomes section. This section does not consider case reports and these should be directed to the dedicated Case Reports section.

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  1. Prolonged QT interval in hemodialysis patients may be associated with sudden cardiac death, however, few studies examined the longitudinal associations of modifiable factors such as serum and dialysate concent...

    Authors: Esther D. Kim, Jacqueline Watt, Larisa G. Tereshchenko, Bernard G. Jaar, Stephen M. Sozio, W. H. Linda Kao, Michelle M. Estrella and Rulan S. Parekh

    Citation: BMC Nephrology 2019 20:133

    Content type: Research article

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  2. The prevalence of chronic kidney disease (CKD) is increasing worldwide and in Africa. Health related quality of life (QOL) has become an essential outcome measure for patients with CKD and end stage renal dise...

    Authors: Elliot K. Tannor, Betty R. Norman, Kwame K. Adusei, Fred S. Sarfo, Mogamat R. Davids and George Bedu-Addo

    Citation: BMC Nephrology 2019 20:122

    Content type: Research article

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  3. Self-management education needs have not been assessed in patients with complex co-morbid conditions such as diabetes and chronic kidney disease (CKD). The objectives of this study were to 1) determine the sel...

    Authors: Edward Zimbudzi, Clement Lo, Peter G. Kerr and Sophia Zoungas

    Citation: BMC Nephrology 2019 20:113

    Content type: Research article

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  6. Protein-energy wasting (PEW) is a relatively prevalent problem among adult haemodialysis patients (HDP). PEW is an important determinant of morbidity and mortality in HDP, therefore it is essential for dietiti...

    Authors: Ali M. Omari, Leen S. Omari, Hazar H. Dagash, Waleed M. Sweileh, Nehal Natour and Sa’ed H. Zyoud

    Citation: BMC Nephrology 2019 20:92

    Content type: Research article

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  7. Darbepoetin alfa (DA-α) is a long-acting erythropoiesis-stimulating glycoprotein which has half-life three-fold longer than that of Erythropoietin alfa (EPO). The objective of this study was to compare the eff...

    Authors: Shubhadeep D. Sinha, Vamsi Krishna Bandi, Bala Reddy Bheemareddy, Pankaj Thakur, Sreenivasa Chary, Kalpana Mehta, Vikranth Reddy Pinnamareddy, Rajendra Pandey, Subhramanyam Sreepada and Santosh Durugkar

    Citation: BMC Nephrology 2019 20:90

    Content type: Research article

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    The Correction to this article has been published in BMC Nephrology 2019 20:415

  8. Assessment of adequacy of intermittent hemodialysis (IHD) is conventionally based upon urea kinetic models for calculation of single pool Kt/Vurea (Kt/V), with 1.2 accepted as minimum adequate clearance for thric...

    Authors: Kelly V. Liang, Jane H. Zhang and Paul M. Palevsky

    Citation: BMC Nephrology 2019 20:82

    Content type: Research article

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  10. Hemodialysis patients suffer from a serious threat of cerebrovascular disease. Klotho, as an aging-suppressor gene, contributes to protect on vascular calcification and oxidative stress, which are the risk fac...

    Authors: Honglan Wei, Hua Li, Xiaohong Song, Xingguo Du, Yuan Cai, Chengxu Li, Liping Dong and Junwu Dong

    Citation: BMC Nephrology 2019 20:63

    Content type: Research article

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  11. Sarcopenia, defined as low muscle mass and strength, is highly prevalent in patients undergoing chronic hemodialysis (HD). However, muscle function and muscle mass do not share the same clinical relevance. In ...

    Authors: Yu-Li Lin, Shu-Yuan Chen, Yu-Hsien Lai, Chih-Hsien Wang, Chiu-Huang Kuo, Hung-Hsiang Liou and Bang-Gee Hsu

    Citation: BMC Nephrology 2019 20:54

    Content type: Research article

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  12. The survival rate for dialysis patients is poor. Previous studies have shown improved survival with home hemodialysis (HHD), but this could be due to patient selection, since HHD patients tend to be younger an...

    Authors: Helena Rydell, Kerstin Ivarsson, Martin Almquist, Mårten Segelmark and Naomi Clyne

    Citation: BMC Nephrology 2019 20:52

    Content type: Research article

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  13. Globally, there is increased clinical interest and uptake of hemodiafiltration (HDF) for increased removal of uremic toxins. To date, there has been no epidemiological analysis of HDF in China. We present HDF ...

    Authors: Weiming Zhang, Changlin Mei, Nan Chen, Xiaoqiang Ding, Zhaohui Ni, Chuanming Hao, Jinghong Zhang, Jinyuan Zhang, Niansong Wang, Gengru Jiang, Zhiyong Guo, Chen Yu, Yueyi Deng, Haiming Li, Qiang Yao, Mark R. Marshall…

    Citation: BMC Nephrology 2019 20:34

    Content type: Research article

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  14. Most people who make the transition to renal replacement therapy (RRT) are treated with a fixed dose thrice-weekly hemodialysis réegimen, without considering their residual kidney function (RKF). Recent papers...

    Authors: Javier Deira, Miguel A. Suárez, Francisca López, Emilio García-Cabrera, Antonio Gascón, Eduardo Torregrosa, Giannina E. García, Jorge Huertas, Jose C. de la Flor, Suleya Puello, Jonathan Gómez-Raja, Jesús Grande, José L. Lerma, Carlos Corradino, Carlos Musso, Manuel Ramos…

    Citation: BMC Nephrology 2019 20:8

    Content type: Study protocol

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  15. Health-related quality of life (HrQoL) varies among dialysis patients. However, little is known about the association of dialysis modality with HrQoL over time. We describe longitudinal patterns of HrQoL among...

    Authors: Nwamaka D. Eneanya, Dugan W. Maddux, Marta M. Reviriego-Mendoza, John W. Larkin, Len A. Usvyat, Frank M. van der Sande, Jeroen P. Kooman and Franklin W. Maddux

    Citation: BMC Nephrology 2019 20:7

    Content type: Research article

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  16. Electronic health record (EHR) data is increasingly used to identify patients with chronic kidney disease (CKD). EHR queries used to capture CKD status, identify comorbid conditions, measure awareness by provi...

    Authors: Martin Frigaard, Anna Rubinsky, Lo Lowell, Anna Malkina, Leah Karliner, Michael Kohn and Carmen A Peralta

    Citation: BMC Nephrology 2019 20:3

    Content type: Research article

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  17. This is the first qualitative study to explore patient decision-making regarding end-stage kidney disease (ESKD) treatment in sub-Saharan Africa. The study addresses an important gap in the literature concerni...

    Authors: Edward Appiah Boateng, Linda East and Catrin Evans

    Citation: BMC Nephrology 2018 19:371

    Content type: Research article

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  18. Evidence regarding the effect of psychosocial factors on hospital readmission in the setting of hemodialysis is limited. We examined whether social worker-assessed factors were associated with 30-day readmissi...

    Authors: Olufunmilola Adisa, Bernard G. Jaar, Tahsin Masud, Abyalew Sahlie, Catherine Obadina, Joshua Ang, Janice P. Lea and Laura C. Plantinga

    Citation: BMC Nephrology 2018 19:360

    Content type: Research article

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  19. Decreased heat shock protein 27 (HSP27) participates in many processes that are involved in cardiovascular (CV) disease. The objective of the study was to evaluate if HSP27 level was predictive of mortality as...

    Authors: Andrzej Jaroszyński, Anna Jaroszyńska, Tomasz Zaborowski, Anna Drelich-Zbroja, Tomasz Zapolski and Wojciech Dąbrowski

    Citation: BMC Nephrology 2018 19:359

    Content type: Research article

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  20. The hepatic circulation is involved in adaptive systemic responses to circulatory stress. However, it is vulnerable to both chronic hypervolemia and cardiac dysfunction. The influence of hemodialysis (HD) and ...

    Authors: Claire J. Grant, Trevor P. Wade, Charles A. McKenzie, Guido Filler, Christopher W. McIntyre and Shih-Han S. Huang

    Citation: BMC Nephrology 2018 19:356

    Content type: Research article

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  21. To date, limited research has been dedicated to exploring the experience of decision-making for chronic kidney disease (CKD) patients who have initiated dialysis and have to make decisions in the context of ma...

    Authors: Danielle Marie Muscat, Roshana Kanagaratnam, Heather L. Shepherd, Kamal Sud, Kirsten McCaffery and Angela Webster

    Citation: BMC Nephrology 2018 19:339

    Content type: Research article

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  22. Caregivers of hemodialysis patients endure a significant caring pressure as a result of caring for patients with chronic illness, which can affect their quality of life. Disruptions in the quality of life of t...

    Authors: Haleh Jafari, Azita Ebrahimi, Abbas Aghaei and Alireza Khatony

    Citation: BMC Nephrology 2018 19:321

    Content type: Research article

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  23. Blood pressure (BP) is currently the main hemodynamic parameter used to assess the influence of fluid removal during hemodialysis session. Since BP is dependent on cardiac output (CO) and total peripheral resi...

    Authors: Yunlin Feng, Yurong Zou, Yifei Zheng, Nathan W. Levin and Li Wang

    Citation: BMC Nephrology 2018 19:310

    Content type: Research article

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  24. The number of elderly patients with end-stage renal disease is increasing rapidly. The higher prevalence of comorbidities and shorter life expectancy in these patients make it difficult to decide on the type o...

    Authors: Eunjin Bae, Hajeong Lee, Dong Ki Kim, Kook-Hwan Oh, Yon Su Kim, Curie Ahn, Jin Suk Han, Sang-Il Min, Seung-Kee Min, Hyo-Cheol Kim and Kwon Wook Joo

    Citation: BMC Nephrology 2018 19:306

    Content type: Research article

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  25. It is debated whether transperitoneal membrane transport of larger (charged) molecules in peritoneal dialysis can be partially governed by the electrokinetic model. In this model, it is postulated that streami...

    Authors: Anneleen Pletinck, Wim Van Biesen, Clement Dequidt and Sunny Eloot

    Citation: BMC Nephrology 2018 19:299

    Content type: Research article

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  26. Patients reaching end-stage renal disease must make a difficult decision regarding renal replacement therapy (RRT) options. Because the choice between dialysis modalities should include patient preferences, it...

    Authors: Jarcy Zee, Junhui Zhao, Lalita Subramanian, Erica Perry, Nicole Bryant, Margie McCall, Yanko Restovic, Delma Torres, Bruce M. Robinson, Ronald L. Pisoni and Francesca Tentori

    Citation: BMC Nephrology 2018 19:298

    Content type: Research article

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  27. Inflammation-based prognostic scores have been used as outcome predictors in patients with cancer or on hemodialysis. However, their role in patients on continuous ambulatory peritoneal dialysis (CAPD) remains...

    Authors: Lu Cai, Jianwen Yu, Jing Yu, Yuan Peng, Habib Ullah, Chunyan Yi, Jianxiong Lin, Xiao Yang and Xueqing Yu

    Citation: BMC Nephrology 2018 19:297

    Content type: Research article

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  28. Arteriovenous fistulae can restrict daily living behaviors involving the upper limbs in hemodialysis patients, but no studies have investigated the detailed effects of an arteriovenous fistula on routine life ...

    Authors: Yuuta Hara, Kosuke Sonoda, Koji Hashimoto, Kazuaki Fuji, Yosuke Yamada and Yuji Kamijo

    Citation: BMC Nephrology 2018 19:284

    Content type: Research article

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  29. Previous clinical studies found inconsistent relationship between circulating sclerostin levels and treatment outcome in patients undergoing maintenance hemodialysis (MHD). Therefore, this study aimed to asses...

    Authors: Aiqun Chen, Ying Sun, Ju Cui, Ban Zhao, Haitao Wang, Xianguang Chen and Yonghui Mao

    Citation: BMC Nephrology 2018 19:264

    Content type: Research article

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  30. Although the efficacy of iron sucrose (IS) and ferric carboxymaltose (FCM) in treating anemia in hemodialysis (HD) patients has been studied individually, a comparison of these two intravenous iron formulation...

    Authors: Jesse M. G. Hofman, Michele F. Eisenga, Adry Diepenbroek, Ilja M. Nolte, Bastiaan van Dam, Ralf Westerhuis, Stephan J. L. Bakker, Casper F. M. Franssen and Carlo A. J. M. Gaillard

    Citation: BMC Nephrology 2018 19:242

    Content type: Research article

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  31. Metabolic syndrome (MetS) has been established as a risk for cardiovascular diseases and mortality in hemodialysis patients. Energy intake (EI) is an important nutritional therapy for preventing MetS. We exami...

    Authors: Tuyen Van Duong, Te-Chih Wong, Hsi-Hsien Chen, Tzen-Wen Chen, Tso-Hsiao Chen, Yung-Ho Hsu, Sheng-Jeng Peng, Ko-Lin Kuo, Hsiang-Chung Liu, En-Tzu Lin, Chi-Sin Wang, I-Hsin Tseng, Yi-Wei Feng, Tai-Yue Chang, Chien-Tien Su and Shwu-Huey Yang

    Citation: BMC Nephrology 2018 19:236

    Content type: Research article

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  32. Emergency start (ES) of dialysis has been associated with worse outcome, but remains poorly documented. This study aims to compare the profile and outcome of a large cohort of patients starting dialysis as an ...

    Authors: Alain Michel, Adelaide Pladys, Sahar Bayat, Cécile Couchoud, Thierry Hannedouche and Cécile Vigneau

    Citation: BMC Nephrology 2018 19:233

    Content type: Research article

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    The Correction to this article has been published in BMC Nephrology 2018 19:266

  33. End-stage renal disease (ESRD) although rare among infants presents many management challenges. We sought to evaluate factors associated with PD catheter failure among infants initiated on chronic PD.

    Authors: Peace D. Imani, Jennifer L. Carpenter, Cynthia S. Bell, Mary L. Brandt, Michael C. Braun and Sarah J. Swartz

    Citation: BMC Nephrology 2018 19:231

    Content type: Research article

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  34. The risk of infective endocarditis (IE) is markedly increased in patients receiving chronic hemodialysis compared with the general population, but outcome data are sparse. The present study investigated causes...

    Authors: Mavish S. Chaudry, Gunnar H. Gislason, Anne-Lise Kamper, Marianne Rix, Anders Dahl, Lauge Østergaard, Emil L. Fosbøl, Trine K. Lauridsen, Louise B. Oestergaard, Christian Hassager, Christian Torp-Pedersen and Niels E. Bruun

    Citation: BMC Nephrology 2018 19:216

    Content type: Research article

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  35. Intradialytic hypotension is a common complication of hemodialysis. The Hemocontrol biofeedback system, improving intradialytic hemodynamic stability, is associated with an initial transient increase in plasma...

    Authors: Esmée M. Ettema, Johanna Kuipers, Martijn van Faassen, Henk Groen, Arie M. van Roon, Joop D. Lefrandt, Ralf Westerhuis, Ido P. Kema, Harry van Goor, Ron T. Gansevoort, Carlo A. J. M. Gaillard and Casper F. M. Franssen

    Citation: BMC Nephrology 2018 19:214

    Content type: Research article

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  36. Obesity is a well-established risk factor for atherosclerosis. However, it is unknown which measure of adiposity best relates to atherosclerosis in relatively lean maintenance hemodialysis (MHD) patients. We a...

    Authors: Chaomin Zhou, Hongying Peng, Jing Yuan, Xin Lin, Yan Zha and Hui Chen

    Citation: BMC Nephrology 2018 19:206

    Content type: Research article

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  37. Conservative care is argued to be a reasonable treatment alternative for dialysis in older patients with advanced chronic kidney disease (CKD). However, comparisons are scarce and generally focus on survival o...

    Authors: Wouter R. Verberne, Janneke Dijkers, Johannes C. Kelder, Anthonius B. M. Geers, Wilbert T. Jellema, Hieronymus H. Vincent, Johannes J. M. van Delden and Willem Jan W. Bos

    Citation: BMC Nephrology 2018 19:205

    Content type: Research article

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    The Research note to this article has been published in BMC Research Notes 2019 12:722

  38. Exercise improves functional outcomes and quality of life of older patients with end-stage renal disease undergoing hemodialysis. Yet exercise is not promoted as part of routine care. Health care providers and...

    Authors: Pia Kontos, Alisa Grigorovich, Romeo Colobong, Karen-Lee Miller, Gihad E. Nesrallah, Malcolm A. Binns, Shabbir M. H. Alibhai, Trisha Parsons, Sarbjit Vanita Jassal, Alison Thomas and Gary Naglie

    Citation: BMC Nephrology 2018 19:195

    Content type: Research article

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  39. Choice of dialysis is context sensitive, explored for PD and extracorporeal dialysis, but less studied for haemodialysis (HD) and hemodiafiltration (HDF), both widely employed in Italy and France; reasons of c...

    Authors: Giorgina Barbara Piccoli, Gianfranca Cabiddu, Maria Rita Moio, Antioco Fois, Riccardo Cao, Ida Molfino, Ana Kaniassi, Francoise Lippi, Ludivine Froger, Antonello Pani and Marilisa Biolcati

    Citation: BMC Nephrology 2018 19:171

    Content type: Research article

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  40. Although fatigue is common in dialysis patients, polypharmacy is seldom listed among its causes. In this report, we describe a dialysis patient who developed severe fatigue due to pharmacological interaction b...

    Authors: Emanuela Cataldo, Valeria Columbano, Louise Nielsen, Lurlynis Gendrot, Bianca Covella and Giorgina Barbara Piccoli

    Citation: BMC Nephrology 2018 19:155

    Content type: Case report

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  41. For patients with end-stage renal failure (ESFR), thrice-weekly hemodialysis is a standard care. Once-weekly hemodialysis combined with low-protein and low-salt dietary treatment (OWHD-DT) have been rarely stu...

    Authors: Toshiyuki Nakao, Yoshie Kanazawa and Toshimasa Takahashi

    Citation: BMC Nephrology 2018 19:151

    Content type: Research article

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  42. Thermometers that measure core (internal) body temperature are the gold standard for monitoring temperature. Despite that most modern hemodialysis machines are equipped with an internal blood monitor that meas...

    Authors: Meaghan Lunney, Bronwyn Tonelli, Rachel Lewis, Natasha Wiebe, Chandra Thomas, Jennifer MacRae and Marcello Tonelli

    Citation: BMC Nephrology 2018 19:137

    Content type: Research article

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  43. Patient activation is associated with better outcomes and lower costs. Although the concept is widely investigated, little attention was given to patient activation and its predictors in patients undergoing he...

    Authors: Liesbet Van Bulck, Kathleen Claes, Katrien Dierickx, Annelies Hellemans, Sofie Jamar, Sven Smets and Gijs Van Pottelbergh

    Citation: BMC Nephrology 2018 19:126

    Content type: Research article

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  44. Inadequate volume control may be a main contributor to poor survival and high mortality in hemodialysis patients. Bioimpedance measurement has the potential to improve fluid management, but several dialysis ce...

    Authors: Jenny Stenberg, Catrin Henriksson, Magnus Lindberg and Hans Furuland

    Citation: BMC Nephrology 2018 19:121

    Content type: Research article

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  45. The impact of the low-protein diet on nutrition in CKD diabetics is uncertain.

    Authors: Vincenzo Bellizzi, Patrizia Calella, Julia Nava Hernández, Verónica Figueroa González, Silvia Moran Lira, Serena Torraca, Rocio Urbina Arronte, Pietro Cirillo, Roberto Minutolo and Rafael A. Montúfar Cárdenas

    Citation: BMC Nephrology 2018 19:110

    Content type: Research article

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  46. Research on factors associated with dialysis withdrawal is scarce. This study examined the predictors that might influence rate of dialysis withdrawal. Existing literature is summarized, analyzed and synthesiz...

    Authors: Hammad Ali Qazi, Helen Chen and Meng Zhu

    Citation: BMC Nephrology 2018 19:96

    Content type: Research article

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  47. Removal of uraemic toxins is inadequate using current dialysis strategies. A new class of dialysis membranes have been developed that allow clearance of larger middle molecules. The REMOVAL-HD study (a tRial E...

    Authors: R. Krishnasamy, C. M. Hawley, M. J. Jardine, M. A. Roberts, Y. J. Cho, M. G. Wong, A. Heath, C. L. Nelson, S. Sen, P. F. Mount, E. M. Pascoe, D. Darssan, L. A. Vergara, P. A. Paul-Brent, N. D. Toussaint, D. W. Johnson…

    Citation: BMC Nephrology 2018 19:89

    Content type: Study protocol

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  48. Metformin associated lactic acidosis (MALA) is a well-known serious side effect of biguanides. However, the best treatment strategy remains a matter of debate. In the last 14 years, we observed a significant i...

    Authors: Andrea Angioi, Gianfranca Cabiddu, Maura Conti, Gianfranco Pili, Alice Atzeni, Valeria Matta, Riccardo Cao, Matteo Floris, Marco Songini, Maria Franca Mulas, Mitchell Rosner and Antonello Pani

    Citation: BMC Nephrology 2018 19:77

    Content type: Research article

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  49. Insufficient vigilance for renal insufficiency is associated with late referral, increased morbidity and mortality. The present study examines whether increased vigilance for chronic kidney disease (CKD) leads...

    Authors: M. De Wilde, M. Speeckaert and W. Van Biesen

    Citation: BMC Nephrology 2018 19:74

    Content type: Research article

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  50. Although aortic calcification has a significant negative impact on prognosis in patients on hemodialysis (HD), risk factors for aortic calcification progression remain unclear. The aim of this study was to inv...

    Authors: Teppei Okamoto, Shingo Hatakeyama, Hirotake Kodama, Hirotaka Horiguchi, Yuka Kubota, Koichi Kido, Masaki Momota, Shogo Hosogoe, Yoshimi Tanaka, Tooru Takashima, Fumitada Saitoh, Tadashi Suzuki and Chikara Ohyama

    Citation: BMC Nephrology 2018 19:71

    Content type: Research article

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ISSN: 1471-2369

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