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  1. Exercise has various positive effects on hemodialysis patients. However, there is no clear evidence which type of exercise yields better results. This study aimed to determine the effects of guided functional ...

    Authors: Špela Bogataj, Jernej Pajek, Jadranka Buturović Ponikvar and Maja Pajek

    Citation: BMC Nephrology 2020 21:352

    Content type: Research article

    Published on:

  2. Hypocomplementemic urticarial vasculitis syndrome is an infrequent condition characterized by ocular, renal, gastrointestinal and pulmonary involvement with low serum complement levels and autoantibodies. Rena...

    Authors: Kalliopi Vallianou, Chrysanthi Skalioti, George Liapis, John N. Boletis and Smaragdi Marinaki

    Citation: BMC Nephrology 2020 21:351

    Content type: Case report

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  3. Acute kidney injury (AKI) is a common complication of cardiac surgery. However, the incidence rate of AKI in patients with congenital heart disease (CHD) greatly varies between reports owing to the different d...

    Authors: Dandan Li, Zhaozhuo Niu, Qiang Huang, Wei Sheng and Tianyi Wang

    Citation: BMC Nephrology 2020 21:350

    Content type: Research article

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  4. Plasma fibrinogen is significantly associated with cardiovascular (CV) events and mortality in the general population. However, the association between plasma fibrinogen and mortality in patients undergoing pe...

    Authors: Jing Yu, Tong Lin, Naya Huang, Xi Xia, Jianbo Li, Yagui Qiu, Xiao Yang, Haiping Mao and Fengxian Huang

    Citation: BMC Nephrology 2020 21:349

    Content type: Research article

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  5. Combined peritoneal dialysis (PD) and hemodialysis (HD) therapy (combined therapy) has numerous clinical benefits and should be emphasized for PD patients encountering technique failure.

    Authors: Mu-Chi Chung, Tung-Min Yu, Ming-Ju Wu, Ya-Wen Chuang, Chih-Hsin Muo, Cheng-Hsu Chen, Chao-Hsiang Chang, Jeng-Jer Shieh, Peir-Haur Hung, Jein-Wen Chen and Chi-Jung Chung

    Citation: BMC Nephrology 2020 21:348

    Content type: Research article

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  6. There is a high prevalence of rare genetic disorders in the Middle East, and their study provides unique clinical and genetic insights. Autosomal recessive polycystic kidney disease (ARPKD) is one of the leadi...

    Authors: Intisar Al Alawi, Elisa Molinari, Issa Al Salmi, Fatma Al Rahbi, Adhra Al Mawali and John A. Sayer

    Citation: BMC Nephrology 2020 21:347

    Content type: Research article

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  7. Nephrotic syndrome (NS) is associated with a hypercatabolic state expressed as an exacerbated degradation of muscle mass. However, the clinical significance of this phenomenon has not yet been investigated.

    Authors: Anna Matyjek, Slawomir Literacki, Stanislaw Niemczyk and Aleksandra Rymarz

    Citation: BMC Nephrology 2020 21:346

    Content type: Research article

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  8. Risk factors predictive of rapid linear chronic kidney disease (CKD) progression and its associations with end-stage renal disease (ESRD) and mortality requires further exploration, particularly as patients wi...

    Authors: Ibrahim Ali, Rajkumar Chinnadurai, Sara T. Ibrahim, Darren Green and Philip A. Kalra

    Citation: BMC Nephrology 2020 21:345

    Content type: Research article

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  9. The prevalence of chronic kidney disease (CKD) in Malaysia was 9.07% in 2011. We aim to determine the current CKD prevalence in Malaysia and its associated risk factors.

    Authors: Thamil Arasu Saminathan, Lai Seong Hooi, Muhammad Fadhli Mohd Yusoff, Loke Meng Ong, Sunita Bavanandan, Wan Shakira Rodzlan Hasani, Esther Zhao Zhi Tan, Irene Wong, Halizah Mat Rifin, Tania Gayle Robert, Hasimah Ismail, Norazizah Ibrahim Wong, Ghazali Ahmad, Rashidah Ambak, Fatimah Othman, Hamizatul Akmal Abd Hamid…

    Citation: BMC Nephrology 2020 21:344

    Content type: Research article

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  10. In the general population, metabolic syndrome (MetS) is predictive of major adverse cardiovascular events (MACE). Waist circumference (WC), a component of the MetS criteria, is linked to visceral obesity, whic...

    Authors: Arnaud Delautre, François Chantrel, Yves Dimitrov, Alexandre Klein, Olivier Imhoff, Clotilde Muller, Nicole Schauder, Thierry Hannedouche and Thierry Krummel

    Citation: BMC Nephrology 2020 21:343

    Content type: Research article

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  11. Preclinical studies have identified both NAD+ and sirtuin augmentation as potential strategies for the prevention and treatment of AKI. Nicotinamide riboside (NR) is a NAD+ precursor vitamin and pterostilbene (PT...

    Authors: Petra Simic, Xavier Fernando Vela Parada, Samir M. Parikh, Ryan Dellinger, Leonard P. Guarente and Eugene P. Rhee

    Citation: BMC Nephrology 2020 21:342

    Content type: Research article

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  12. Genetic changes in the LIM homeobox transcription factor 1 beta (LMX1B) have been associated with focal segmental glomerulosclerosis (FSGS) without the extra-renal or ultrastructural manifestations of Nail-patell...

    Authors: Filippo Pinto e Vairo, Pavel N. Pichurin, Fernando C. Fervenza, Samih H. Nasr, Kevin Mills, Christopher T. Schmitz, Eric W. Klee and Sandra M. Herrmann

    Citation: BMC Nephrology 2020 21:341

    Content type: Case report

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  13. MIRAGE syndrome is a recently discovered rare genetic disease characterized by myelodysplasia (M), infection (I), growth restriction (R), adrenal hypoplasia (A), genital phenotypes (G), and enteropathy (E), ca...

    Authors: Sho Ishiwa, Koichi Kamei, Kanako Tanase-Nakao, Shinsuke Shibata, Kunihiro Matsunami, Ichiro Takeuchi, Mai Sato, Kenji Ishikura and Satoshi Narumi

    Citation: BMC Nephrology 2020 21:340

    Content type: Case report

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  14. The nucleotide reverse transcriptase inhibitor Tenofovir Alafenamide (TAF) is a novel pro-drug of tenofovir (TFV) and possesses a superior renal safety profile compared with tenofovir disoproxil fumerate (TDF)...

    Authors: Jack E. Heron, Mark Bloch, Vinay Vanguru, John Saunders and David M. Gracey

    Citation: BMC Nephrology 2020 21:339

    Content type: Case report

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  16. Percutaneous renal biopsy (PRB) is the primary biopsy technique and it was used by 16G needles or 18G needles in China, but there is controversy about the effect and safety of the two different diameters. The ...

    Authors: Weiji Xie, Jing Xu, Yi Xie, Zhijun Lin, Xiaochang Xu, Xialan Zhang and Yimin Zhang

    Citation: BMC Nephrology 2020 21:337

    Content type: Research article

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  17. There is considerable state-level variation in the incidence of dialysis-requiring acute kidney injury (AKI-D). However, little is known about reasons for this geographic variation.

    Authors: Zijin Chen, Charles E. McCulloch, Neil R. Powe, Michael Heung, Rajiv Saran, Meda E. Pavkov, Nilka Rios Burrows, Raymond K. Hsu and Chi-yuan Hsu

    Citation: BMC Nephrology 2020 21:336

    Content type: Research article

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  18. Renal artery aneurysms (RAAs) are rare and usually asymptomatic, and some RAAs can be associated with calcifications, which may lead to misdiagnoses as renal calculi, which are then mistakenly treated.

    Authors: Chao Chen, Xuliang Wang, Fang Xin, Lugeng He, Kang Jiang, Jia Shao and Liping Xie

    Citation: BMC Nephrology 2020 21:335

    Content type: Case report

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  19. Chronic Kidney Disease (CKD) patients frequently develop life-impairing bone mineral disorders. Despite the reported impact of exercise on bone health, systematic reviews of the evidence are lacking. This revi...

    Authors: Daniela F. Cardoso, Elisa A. Marques, Diogo V. Leal, Aníbal Ferreira, Luke A. Baker, Alice C. Smith and João L. Viana

    Citation: BMC Nephrology 2020 21:334

    Content type: Research article

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  21. Hyperkalemia (HK) can affect health outcomes and quality of life, as it is referred to as a potentially life-threatening condition caused by an increased serum potassium concentration in the blood. Patients su...

    Authors: Jennifer Scarlet Haas, Kim-Sarah Krinke, Christopher Maas, Thomas Hardt, Isabella Barck and Sebastian Braun

    Citation: BMC Nephrology 2020 21:332

    Content type: Research article

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  22. Hemodialysis patients have a high risk of mortality. The most common causes of death are cardiovascular disease and infection. The potential hazard or benefit associated with vitamin D use and cardiovascular o...

    Authors: Jo-Yen Chao, Chung-Yi Li, Ming-Cheng Wang and Yea-Huei Kao Yang

    Citation: BMC Nephrology 2020 21:331

    Content type: Research article

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  23. Patients with kidney failure experience a complex decision on dialysis modality performed either at home or in hospital. The options have different levels of impact on their physical and psychological conditio...

    Authors: Jeanette Finderup, Kirsten Lomborg, Jens Dam Jensen and Dawn Stacey

    Citation: BMC Nephrology 2020 21:330

    Content type: Research article

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  24. Depression and frailty contribute to the adverse clinical outcome of peritoneal dialysis (PD) patients. However, the interaction between depression and frailty in PD patients remains uncertain. We determined t...

    Authors: Gordon Chun-Kau Chan, Jack Kit-Chung Ng, Kai-Ming Chow, Bonnie Ching-Ha Kwan, Vickie Wai-Ki Kwong, Wing-Fai Pang, Phyllis Mei-Shan Cheng, Man-Ching Law, Chi-Bon Leung, Philip Kam-Tao Li and Cheuk-Chun Szeto

    Citation: BMC Nephrology 2020 21:329

    Content type: Research article

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  25. Gitelman syndrome is a rare salt-losing renal tubular disorder associated with mutation of SLC12A3 gene, which encodes the Na-Cl co-transporter (NCCT). Gitelman syndrome is characterized by hypokalemia, metabolic...

    Authors: Bingzi Dong, Ying Chen, Xinying Liu, Yangang Wang, Fang Wang, Yuhang Zhao, Xiaofang Sun and Wenjuan Zhao

    Citation: BMC Nephrology 2020 21:328

    Content type: Research article

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  26. Familial distal renal tubular acidosis (dRTA) associated with mutations of solute carrier family 4 membrane − 1 (SLC4A1) gene could co-exist with red cell membrane abnormality, Southeast Asian ovalocytosis (SAO)....

    Authors: WMSN Gunaratne, DMDIB Dissanayake, KADS Jayaratne, NP Premawardhana and Sisira Siribaddana

    Citation: BMC Nephrology 2020 21:327

    Content type: Case report

    Published on:

  27. Coronavirus disease-2019 (COVID-19) is an ongoing pandemic which has affected over 12 million people across the globe. Manifestations in different organs systems are being reported regularly. Renal biopsy find...

    Authors: Rajib K. Gupta, Ramya Bhargava, Al-Aman Shaukat, Emily Albert and John Leggat

    Citation: BMC Nephrology 2020 21:326

    Content type: Case report

    Published on:

  28. Cardiorenal syndrome (CRS), a serious condition with high morbidity and mortality, is characterized by the coexistence of cardiac abnormality and renal dysfunction. There is limited information about CRS in as...

    Authors: Sorasak Makmettakul, Adisak Tantiworawit, Arintaya Phrommintikul, Pokpong Piriyakhuntorn, Thanawat Rattanathammethee, Sasinee Hantrakool, Chatree Chai-Adisaksopha, Ekarat Rattarittamrong, Lalita Norasetthada, Kanda Fanhchaksai, Pimlak Charoenkwan and Suree Lekawanvijit

    Citation: BMC Nephrology 2020 21:325

    Content type: Research article

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  29. Dyslipidemia is common in patients with chronic kidney disease and particular prevalent in patients receiving peritoneal dialysis. However, whether markers of atherogenic dyslipidemia correlate with outcomes i...

    Authors: Wenkai Xia, Xiajuan Yao, Yan Chen, Jie Lin, Volker Vielhauer and Hong Hu

    Citation: BMC Nephrology 2020 21:324

    Content type: Research article

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  30. Thrombotic microangiopathy (TMA) is a histopathological entity associated with microangiopathic hemolytic anemia, thrombocytopenia, and end-organ ischemic damage. Although TMA is caused by various diseases, th...

    Authors: Kentaro Nishi, Mai Sato, Masao Ogura, Mika Okutsu, Kenji Ishikura and Koichi Kamei

    Citation: BMC Nephrology 2020 21:323

    Content type: Case report

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  31. Patients with End-Stage Renal Disease (ESRD) are at an increased risk for restrictive lung disease due to accumulation of uremic toxins and volume overload. Hemodialysis is the preferred treatment for improvin...

    Authors: Thatsaphan Srithongkul, Owen D. Lyons, Rose Faratro and Christopher T. Chan

    Citation: BMC Nephrology 2020 21:322

    Content type: Case report

    Published on:

  32. Likelihood of developing acute kidney injury (AKI) increases with age. We aimed to explore whether the predictability of AKI varies between age groups and assess the volatility of risk factors using electronic...

    Authors: Lijuan Wu, Yong Hu, Xiangzhou Zhang, Weiqi Chen, Alan S. L. Yu, John A. Kellum, Lemuel R. Waitman and Mei Liu

    Citation: BMC Nephrology 2020 21:321

    Content type: Research article

    Published on:

  33. Renal biopsy is often required to obtain information for diagnosis, management and prognosis of kidney disease that can be broadly classified into acute kidney injury (AKI) and chronic kidney disease (CKD). Th...

    Authors: Joseph Patrick Burke, Manaf Aljishi, Leo Francis, Wendy Hoy, Dakshinamurthy Divi, Roy Cherian, Jeremy Frazier, Glenda Gobe, Pedro Gois, Sridevi Govindarajulu, Sonny Huynh, Shilpanjali Jesudason, George John, Krishan Madhan, Andrew Mallett, Valli Manickam…

    Citation: BMC Nephrology 2020 21:320

    Content type: Database

    Published on:

  34. Hemolytic uremic syndrome (HUS), a common subtype of thrombotic microangiopathy (TMA), is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. Shiga toxin-producing Esche...

    Authors: Chuan Shi, Chao Li, Wei Ye, Wen-ling Ye and Ming-xi Li

    Citation: BMC Nephrology 2020 21:319

    Content type: Case report

    Published on:

  35. Due to the high incidence and mortality of sepsis-associated acute kidney injury, a significant number of studies have explored the causes of sepsis-associated acute kidney injury (AKI). However, the opinions ...

    Authors: Jiefeng Liu, Hebin Xie, Ziwei Ye, Fen Li and Lesan Wang

    Citation: BMC Nephrology 2020 21:318

    Content type: Research article

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  36. Elevated levels of serum indoxyl sulfate (IS) have been linked to cardiovascular complications in patients with chronic kidney disease (CKD). Oral sorbent therapy using spherical carbons selectively attenuates...

    Authors: Seok-hyung Kim, Jong Hyun Jhee, Hoon Young Choi, Sang-Ho Lee, Sug Kyun Shin, So-Young Lee, Dong Ho Yang, Joo-Hark Yi, Sang-Woong Han, Young-Il Jo and Hyeong Cheon Park

    Citation: BMC Nephrology 2020 21:317

    Content type: Research article

    Published on:

  37. It is controversial for the effect and safety between cinacalcet and other treatments in treating secondary hyperparathyroidism for patients with chronic kidney disease (CKD) or end-stage renal disease (ESRD).

    Authors: Yiting Sun, Binyao Tian, Zitong Sheng, Pengzhi Wan, Tianhua Xu and Li Yao

    Citation: BMC Nephrology 2020 21:316

    Content type: Research article

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  38. IgG4-related disease (IgG4-RD) is a newly classified but poorly understood immune-medicated systemic disease. It causes potential fibroinflammation in one or more organs, characterized by tumescent organs and ...

    Authors: Hui Wang, Tao Su, Lei Kang, Li Yang and Suxia Wang

    Citation: BMC Nephrology 2020 21:315

    Content type: Case report

    Published on:

  39. Patients with chronic kidney disease make day-to-day decisions about how to self-manage their disease. Chronic kidney disease (CKD) includes a risk for progression towards end-stage renal disease and the devel...

    Authors: Une Elisabeth Stømer, Astrid Klopstad Wahl, Lasse Gunnar Gøransson and Kristin Hjorthaug Urstad

    Citation: BMC Nephrology 2020 21:314

    Content type: Research article

    Published on:

  40. Lupus nephritis (LN) is one of most common types of secondary glomerulonephritis, which is characterized by longitudinal pathological changes. Microstructural lesions of LN will impact the motion of water mole...

    Authors: Huilan Shi, Yanyan Wang, Tiekun Yan, Junya Jia, Dong Li, Li Wei, Wenya Shang and Zhenfeng Zheng

    Citation: BMC Nephrology 2020 21:313

    Content type: Research article

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  41. To explore, in a large group of patients with type-2 diabetes (T2DM), renal function decline in terms of the slope of the estimated glomerular filtration rate (eGFR) over time, and to find out how classical ri...

    Authors: Peter Bramlage, Stefanie Lanzinger, Eva Hess, Simon Fahrner, Christoph H. J. Heyer, Mathias Friebe, Ivo Buschmann, Thomas Danne, Reinhard W. Holl and Jochen Seufert

    Citation: BMC Nephrology 2020 21:312

    Content type: Research article

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  42. Although acute kidney injury (AKI) is a known risk factor for adverse clinical outcomes in patients with spontaneous intracerebral haemorrhage (SICH), little is known about the predisposing factors that contri...

    Authors: Zhenhuan Zou, Siying Chen, Yinshuang Li, Jiawei Cai, Yulu Fang, Jingzhi Xie, Wenhua Fang, Dezhi Kang and Yanfang Xu

    Citation: BMC Nephrology 2020 21:311

    Content type: Research article

    Published on:

  43. There are conflicting research results about the survival differences between hemodialysis(HD) and peritoneal dialysis (PD). The present study estimated the survival and the relative mortality hazard for incid...

    Authors: Xi Yao, Wenhua Lei, Nan Shi, Weiqiang Lin, Xiaoying Du, Ping Zhang and Jianghua Chen

    Citation: BMC Nephrology 2020 21:310

    Content type: Research article

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  44. The editorial comments on a recently published study in which 242 patients, with “stable” chronic kidney disease, recruited during a hospital stay, were randomised either to receiving support from nephrologist...

    Authors: Giorgina Barbara Piccoli

    Citation: BMC Nephrology 2020 21:309

    Content type: Correspondence

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  45. Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide. Inflammatory mediators have been implicated in the pathogenesis of DN, thus considered an inflammatory disease. However, fur...

    Authors: Liliane Silvano Araújo, Bianca Gonçalves Silva Torquato, Crislaine Aparecida da Silva, Maria Luíza Gonçalves dos Reis Monteiro, Ana Luisa Monteiro dos Santos Martins, Marcos Vinícius da Silva, Marlene Antônia dos Reis and Juliana Reis Machado

    Citation: BMC Nephrology 2020 21:308

    Content type: Research article

    Published on:

  46. Ischaemia/reperfusion (I/R) injury is associated with renal tissue damage during deceased donor renal transplantation. The effect of mannitol to reduce I/R injury during graft reperfusion in renal transplant r...

    Authors: Christian Reiterer, Karin Hu, Samir Sljivic, Markus Falkner von Sonnenburg, Edith Fleischmann, Alexander Kainz and Barbara Kabon

    Citation: BMC Nephrology 2020 21:307

    Content type: Research article

    Published on:

  47. Haemodiafilteration (HDF) is a promising new modality of renal replacement therapy (RRT). It is an improvement in the quality of hemodialysis (HD) and thus in the quality of patients’lives. The main obstacle t...

    Authors: Magid A. A. Ibrahim, Ihab Z. ElHakim, Dina Soliman, Muhammad A. Mubarak and Ragia M. Said

    Citation: BMC Nephrology 2020 21:306

    Content type: Research article

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  48. Hyper-pulsatility of hemodialysis arteriovenous fistula (AVF) is the basic physical examination finding when there is outflow stenosis. The arm elevation test can also be utilized to detect outflow stenosis. I...

    Authors: Matt Chiung-Yu Chen, Mei-Jui Weng, Bai-Chun Chang, Hsiu-Ching Lai, Misoso Yi-Wen Wu, Chia-Yun Fu, Yi-Chun Liu and Wen-Che Chi

    Citation: BMC Nephrology 2020 21:304

    Content type: Research article

    Published on:

  49. Accumulation of iron is associated with oxidative stress, inflammation, and regulated cell death processes that contribute to the development of acute kidney injury (AKI). We aimed to investigate the associati...

    Authors: Jie Shu, Yufeng Hu, Xueshu Yu, Jiaxiu Chen, Wenwei Xu and Jingye Pan

    Citation: BMC Nephrology 2020 21:303

    Content type: Research article

    Published on:

  50. Hemodialysis (HD) tend to have more hemodynamic changes than peritoneal dialysis (PD), which aggravates inflammation and oxidative stress. Whether HD and PD have different effects on the progression of vascula...

    Authors: Qingyu Niu, Huiping Zhao, Li Zuo, Mei Wang and Liangying Gan

    Citation: BMC Nephrology 2020 21:302

    Content type: Research article

    Published on:

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