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  1. Critically ill coronavirus disease 2019 (COVID-19) patients have a high risk of acute kidney injury (AKI) that requires renal replacement therapy (RRT). A state of hypercoagulability reduces circuit life spans...

    Authors: Frederic Arnold, Lukas Westermann, Siegbert Rieg, Elke Neumann-Haefelin, Paul Marc Biever, Gerd Walz, Johannes Kalbhenn and Yakup Tanriver

    Citation: BMC Nephrology 2020 21:486

    Content type: Research article

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  2. The purpose of this study was to explore the effect of changing treatment to high-flux hemodialysis (HFHD) on mortality rate in patients with long-term low flux hemodialysis (LFHD).

    Authors: Shuxin Liu, Hong Liu, Zhihong Wang, Lanbo Teng, Cui Dong, Tingting Gui and Yu Zhang

    Citation: BMC Nephrology 2020 21:485

    Content type: Research article

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  3. There is concern about the impact of immunosuppressive agents taken by male kidney transplant (KT) recipients on the risk of foetal malformations. The aim of our survey was to estimate the paternity rate and t...

    Authors: Annabel Boyer, Thierry Lobbedez, Mohamed Ouethrani, Angélique Thuillier Lecouf, Nicolas Bouvier, Valérie Châtelet and Bruno Hurault de Ligny

    Citation: BMC Nephrology 2020 21:483

    Content type: Research article

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  4. FGF23 controls serum l,25(OH)2D3 levels and phosphate homeostasis. This study evaluates the effects of ferritin on intact PTH, FGF23, and l,25(OH)2D3 in patients with major thalassemia. It also evaluates FGF23 ch...

    Authors: Forough Saki, Azita Salehifar, Seyed Reza Kassaee and Gholamhossein Ranjbar Omrani

    Citation: BMC Nephrology 2020 21:482

    Content type: Research article

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  5. The largest data on the epidemiology of primary glomerular diseases (PGDs) are obtained from the databases of countries or centers. Here, we present the extended results of the Primary Glomerular Diseases Stud...

    Authors: Aydin Turkmen, Abdullah Sumnu, Egemen Cebeci, Halil Yazici, Necmi Eren, Nurhan Seyahi, Kamil Dilek, Fatih Dede, Ulver Derici, Abdulkadir Unsal, Garip Sahin, Murat Sipahioglu, Mahmut Gok, Erhan Tatar, Belda Dursun, Savas Sipahi…

    Citation: BMC Nephrology 2020 21:481

    Content type: Research article

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  6. Hepatitis C virus (HCV) infects more than 71 million people worldwide and chronic HCV infection increases the risk of liver cirrhosis and failure. Haemodialysis (HD) is one of the renal replacement therapies w...

    Authors: Xue Zheng Wong, Chye Chung Gan, Rosmawati Mohamed, Rosnawati Yahya, Shubash Ganapathy, Soek Siam Tan and Soo Kun Lim

    Citation: BMC Nephrology 2020 21:480

    Content type: Research article

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  7. Secondary hyperparathyroidism (SHPT) is a common complication in end-stage renal disease (ESRD) patients, and parathyroidectomy (PTX) is an effective treatment intervention of SHPT. However, the curative impac...

    Authors: Shaohua Chen, Kaixiang Sheng, Ying Shen, Hua Jiang, Xin Lei, Lihui Qu, Chunping Xu, Jianghua Chen and Ping Zhang

    Citation: BMC Nephrology 2020 21:479

    Content type: Research article

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  8. Advance Care Planning is recommended for people with end-stage kidney disease but evidence is limited. Robust clinical trials are needed to investigate the impact of advance care planning in this population. T...

    Authors: Peter O’Halloran, Helen Noble, Kelly Norwood, Peter Maxwell, Fliss Murtagh, Joanne Shields, Robert Mullan, Michael Matthews, Christopher Cardwell, Mike Clarke, Rachael Morton, Karan Shah, Trisha Forbes and Kevin Brazil

    Citation: BMC Nephrology 2020 21:478

    Content type: Research article

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  9. Annual decline in kidney function is a widely applied surrogate outcome of renal failure. It is important to understand the relationships between known risk factors and the annual decline in estimated glomerul...

    Authors: Tadashi Toyama, Kiyoki Kitagawa, Megumi Oshima, Shinji Kitajima, Akinori Hara, Yasunori Iwata, Norihiko Sakai, Miho Shimizu, Atsushi Hashiba, Kengo Furuichi and Takashi Wada

    Citation: BMC Nephrology 2020 21:477

    Content type: Research article

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  10. Hypertensive nephropathy (HTN) is a kind of renal injury caused by chronic hypertension, which seriously affect people’s life. The purpose of this study was to identify the potential biomarkers of HTN and unde...

    Authors: Zhen Wang, Zhongjie Liu, Yingxia Yang and Lei Kang

    Citation: BMC Nephrology 2020 21:476

    Content type: Research article

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  11. Aerobic exercise capacity is reduced in non-dialysis chronic kidney disease (CKD), but the magnitude of changes in exercise capacity over time is less known. Our main hypothesis was that aerobic ExCap would de...

    Authors: Helena Wallin, Eva Jansson, Carin Wallquist, Britta Hylander Rössner, Stefan H. Jacobson, Anette Rickenlund and Maria J. Eriksson

    Citation: BMC Nephrology 2020 21:475

    Content type: Research article

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  12. Peritoneal dialysis-associated peritonitis can uncommonly be caused by fungal infections. When they do present, they are associated with significant mortality and morbidity. We describe a case where a sample o...

    Authors: Victoria Jane Carnall, Stephanie Murdock, Cressida Auckland and Christopher J. Mulgrew

    Citation: BMC Nephrology 2020 21:474

    Content type: Case report

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  13. As organs infected with Hepatitis C virus (HCV) provide an opportunity to expand the donor pool, the primary aim of this study is to explore patient willingness to accept a kidney from HCV-infected donors comp...

    Authors: Gretchen C. Edwards, Maren E. Shipe, Lindsay Smith, Christianna Gamble, David Shaffer, Beatrice P. Concepcion and Rachel Forbes

    Citation: BMC Nephrology 2020 21:473

    Content type: Research article

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  14. The caregivers of children on peritoneal dialysis face heavy care burdens and may have a high risk of depression. This study aimed to describe the prevalence and severity of depression and identify its related...

    Authors: Rui Zhao, Ying Gu, Xia Shen, Xianying Mai, Cheng Zhou, Yufen Zhang, Yihui Zhai, Qian Shen, Hong Xu and Qing Zhou

    Citation: BMC Nephrology 2020 21:472

    Content type: Research article

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  15. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) to ALT ratio (AST/ALT ratio) have been shown to be related to non-alcoholic fatty liver disease or insulin resistance, which was associated w...

    Authors: Hirotaka Ochiai, Takako Shirasawa, Takahiko Yoshimoto, Satsue Nagahama, Akihiro Watanabe, Ken Sakamoto and Akatsuki Kokaze

    Citation: BMC Nephrology 2020 21:471

    Content type: Research article

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  16. Coronavirus Disease 2019 (COVID-19) has substantially impacted the provision of medical services. During the pandemic, many medical services, including facilities providing care to patients with end stage rena...

    Authors: Hossein Akbarialiabad, Shahin Kavousi, Aria Ghahramani, Bahar Bastani and Nasrollah Ghahramani

    Citation: BMC Nephrology 2020 21:470

    Content type: Research article

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  17. Hydroxychloroquine (HCQ) is a well-known immunomodulator that was recently used in immunoglobulin A (IgA) nephropathy (IgAN) due to its antiproteinuric effects. We investigated the effects of HCQ in patients w...

    Authors: Chen Tang, Ji-Cheng Lv, Su-Fang Shi, Yu-Qing Chen, Li-Jun Liu and Hong Zhang

    Citation: BMC Nephrology 2020 21:469

    Content type: Research article

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  19. Chronic kidney disease (CKD) is a growing challenge in low- and middle-income countries, particularly in sub-Saharan Africa. There is insufficient population-based data on CKD in Nigeria that is required to es...

    Authors: Timothy Olusegun Olanrewaju, Ademola Aderibigbe, Ademola Alabi Popoola, Kolawole Thomas Braimoh, Mikhail Olayinka Buhari, Olanrewaju Timothy Adedoyin, Sulyman Alege Kuranga, Sikiru Abayomi Biliaminu, Adindu Chijioke, Abdulwahab Akanbi Ajape, Diederick E Grobbee, Peter J Blankestijn and Kerstin Klipstein-Grobusch

    Citation: BMC Nephrology 2020 21:467

    Content type: Research article

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  20. We questioned whether the introduction of a subjective evaluation of patient-specific goals, could be used as a valid method to assess the effectiveness of inpatient rehabilitation.

    Authors: Takahiro Shimoda, Helen Alston, Angelique Chai and Sarbjit V. Jassal

    Citation: BMC Nephrology 2020 21:466

    Content type: Research article

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  21. Live kidney donors (LKDs) account for nearly a third of kidney transplants in the United States. While donor nephrectomy poses minimal post-surgical risk, LKDs face an elevated adjusted risk of developing chro...

    Authors: Macey L. Levan, Madeleine M. Waldram, Sandra R. DiBrito, Alvin G. Thomas, Fawaz Al Ammary, Shane Ottman, Jaclyn Bannon, Daniel C. Brennan, Allan B. Massie, Joseph Scalea, Rolf N. Barth, Dorry L. Segev and Jacqueline M. Garonzik-Wang

    Citation: BMC Nephrology 2020 21:465

    Content type: Study protocol

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  22. A relationship exists between birth weight (BW) and glomerular filtration rate (GFR) in postnatal kidney. Willing to fill a gap of knowledge in sub-Saharan Africa, we assessed the effect of BW on blood pressur...

    Authors: Francois Folefack Kaze, Seraphin Nguefack, Constantine Menkoh Asong, Jules Clement Nguedia Assob, Jobert Richie Nansseu, Mathurin Pierre Kowo, Victorine Nzana, Ginette Claude Mireille Kalla and Marie Patrice Halle

    Citation: BMC Nephrology 2020 21:464

    Content type: Research article

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  23. Angioimmunoblastic T cell lymphoma (AITL) is an infrequent hematological malignancy with variable and often atypical presentations. The presence of dysproteinemia, autoantibodies and systemic involvement in AI...

    Authors: Xiang-Yang Li, Hai-Yan He, Shu-Ling Yue and Pearl Pai

    Citation: BMC Nephrology 2020 21:463

    Content type: Case report

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  24. Most patients with cystic fibrosis (CF) present with respiratory or digestive symptoms. About 3% of patients have electrolyte disturbances at the time of diagnosis, but most of the described cases presenting w...

    Authors: Yangming Cao, Rachel Donaldson and David Lee

    Citation: BMC Nephrology 2020 21:462

    Content type: Case report

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  25. Renal replacement therapy (RRT) is usually indicated for patients with chronic kidney disease (CKD) with glomerular filtration rate below 10 ml/ml/min/1.73m2. However, the need for RRT and timing of dialysis init...

    Authors: Venceslau A. Coelho, Giovani GN. Santos, Carla M. Avesani, Cicero Italo L. Bezerra, Luana Cristina A. Silva, Julia C. Lauar, Bengt Lindholm, Peter Stenvinkel, Wilson Jacob-Filho, Irene L. Noronha, Roberto Zatz, Rosa M. A. Moysés and Rosilene M. Elias

    Citation: BMC Nephrology 2020 21:461

    Content type: Study protocol

    Published on:

  26. Although cardiovascular diseases in particular Pulmonary Arterial Hypertension (PAH) is associated with, high morbid-mortality in chronic hemodialysis, but its magnitude remains paradoxically unknown in sub-Sa...

    Authors: Yannick Mompango Engole, François Bompeka Lepira, Yannick Mayamba Nlandu, Yves Simbi Lubenga, Augustin Luzayadio Longo, Aliocha Nkodila, Jean-Robert Rissassy Makulo, Vieux Momeme Mokoli, Justine Busanga Bukabau, Marie-France Ingole Mboliasa, Evariste Mukendi Kadima, Cedric Kabemba Ilunga, Tresor Swambulu Mvunzi, Nazaire Mangani Nseka and Ernest Kiswaya Sumaili

    Citation: BMC Nephrology 2020 21:460

    Content type: Research article

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  27. Fatty acid-binding protein 4 (FABP4), but not FABP1 (liver-type FABP), is ectopically induced in injured glomerular endothelial cells, and urinary FABP4 (U-FABP4) level is associated with proteinuria and renal...

    Authors: Marenao Tanaka, Masato Furuhashi, Norihito Moniwa, Takuto Maeda, Hideki Takizawa, Megumi Matsumoto, Akiko Sakai, Yukimura Higashiura, Yufu Gocho, Masayuki Koyama, Yayoi Ogawa and Tetsuji Miura

    Citation: BMC Nephrology 2020 21:459

    Content type: Research article

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  28. Transplantation with a diabetic donor kidney may have some benefits compared to remaining on the waitlist for selected patients. However, we found that some kidney transplant recipients have ongoing donor-tran...

    Authors: Chia-Tien Hsu, Mei-Chin Wen, Hsien-Fu Chiu, Shang-Feng Tsai, Tung-Min Yu, Cheng-Kuang Yang, Ming-Ju Wu and Cheng-Hsu Chen

    Citation: BMC Nephrology 2020 21:458

    Content type: Research article

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  29. Chronic kidney disease (CKD) requires lifelong self-management. With the rise in access to the Internet, many CKD patients and their caregivers increasingly use the internet for information on CKD self-managem...

    Authors: Rohanit Singh, Bernard G. Jaar, Gibran Kazi and Lawrence J. Appel

    Citation: BMC Nephrology 2020 21:457

    Content type: Research article

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  30. Acute kidney injury (AKI) is a major complication following liver resection. The aim of this study was to determine the risk factors for AKI after hepatic resection and whether intraoperative hypotension (IOH)...

    Authors: Pingping Liao, Shuo Zhao, Lin Lyu, Xuanlong Yi, Xiangyu Ji, Jian Sun, Yanfang Jia and Zangong Zhou

    Citation: BMC Nephrology 2020 21:456

    Content type: Research article

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  31. Renal angiomyolipoma (RAML) is a rare benign kidney tumour comprised of adipose tissue, smooth muscle, and blood vessels. It can cause fatal complications if it ruptures. Although there have been reports of RA...

    Authors: Zechuan Liu, Yinghua Zou, Tianshi Lv, Haitao Guan and Zeyang Fan

    Citation: BMC Nephrology 2020 21:455

    Content type: Case report

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  32. Renal function is a key factor of cardiovascular disease. Carotid intima-media thickness (IMT) has been widely used as a marker of early subclinical atherosclerosis. The determinants of cystatin C, a novel mar...

    Authors: Chiu-Shong Liu, Chia-Ing Li, Yuh-Cherng Guo, Chih-Hsueh Lin, Wen-Yuan Lin, Chung-Hsiang Liu, Mu-Cyun Wang, Chuan-Wei Yang, Shing-Yu Yang, Tsai-Chung Li and Cheng-Chieh Lin

    Citation: BMC Nephrology 2020 21:454

    Content type: Research article

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  33. In chronic kidney disease (CKD), patients’ adherence to prescriptions for diet and for medications might depend on the degree to which they have hope that they will enjoy life, and that hope could vary with th...

    Authors: Noriaki Kurita, Takafumi Wakita, Yoshitaka Ishibashi, Shino Fujimoto, Masahiko Yazawa, Tomo Suzuki, Kenichiro Koitabashi, Mai Yanagi, Hiroo Kawarazaki, Joseph Green, Shunichi Fukuhara and Yugo Shibagaki

    Citation: BMC Nephrology 2020 21:453

    Content type: Research article

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  34. Troponin T (TnT) is a well-known risk factor for negative outcome in hemodialysis (HD) patients, but little is known about variation over time, and the impact of clinical and dialysis specific factors. This st...

    Authors: Christian D. Peters, Krista D. Kjaergaard, Kent L. Christensen, Bo M. Bibby, Bente Jespersen and Jens D. Jensen

    Citation: BMC Nephrology 2020 21:452

    Content type: Research article

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  35. Aging and mortality of patients on waiting lists for kidney transplantation have increased, as a result of the shortage of organs available all over the world. Living donor grafts represent a significant sourc...

    Authors: Rostand Emmanuel Nguefouet Momo, Paola Donato, Gabriele Ugolini, Francesco Nacchia, Luca Mezzetto, Gian Franco Veraldi, Stefano Marletta, Enrico Cavallo, Albino Eccher, Annamaria Giambanco, Daniela Cenzi and Luigino Boschiero

    Citation: BMC Nephrology 2020 21:451

    Content type: Case report

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  36. SLE manifestations after ESRD may be underdiagnosed and undertreated, contributing to increased morbidity and mortality. Whether specific symptoms persist after ESRD or a shift towards new manifestations occur...

    Authors: Maria Salgado Guerrero, Alejandra Londono Jimenez, Chrisanna Dobrowolski, Wenzhu B. Mowrey, Beatrice Goilav, Shudan Wang and Anna Broder

    Citation: BMC Nephrology 2020 21:450

    Content type: Research article

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  37. The pandemic of coronavirus disease 2019 (CoVID-19) has been an unprecedented period. The disease afflicts multiple organ systems, with acute kidney injury (AKI) a major complication in seriously ill patients....

    Authors: Sam Kant, Steven P. Menez, Mohamed Hanouneh, Derek M. Fine, Deidra C. Crews, Daniel C. Brennan, C. John Sperati and Bernard G. Jaar

    Citation: BMC Nephrology 2020 21:449

    Content type: Review

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  38. Patients on continuous ambulatory peritoneal dialysis (PD) are encouraged to warm dialysate to 37 °C before peritoneal infusion; main international PD guidelines do not provide specific recommendation, and pat...

    Authors: Francesco Fontana, Chiara Torelli, Silvia Giovanella, Giulia Ligabue, Gaetano Alfano, Karin Gerritsen, Rafael Selgas and Gianni Cappelli

    Citation: BMC Nephrology 2020 21:448

    Content type: Research article

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  39. Interstitial fibrosis/tubular atrophy (T) score is a known determinant of the progression of immunoglobulin A nephropathy (IgAN). Strong evidence indicates that the components of the coagulation system closely...

    Authors: Ming Xia, Di Liu, Liang Peng, Yan Li, Haiyang Liu, Lingzhi Wu, Guochun Chen, Yu Liu and Hong Liu

    Citation: BMC Nephrology 2020 21:447

    Content type: Research article

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  40. Acute kidney injury (AKI) is a known risk factor for chronic kidney disease (CKD) and end stage kidney disease (ESKD). The progression from AKI to CKD, despite being well recognised, is not completely understo...

    Authors: Anam Asad, James O. Burton and Daniel S. March

    Citation: BMC Nephrology 2020 21:446

    Content type: Review

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  41. Chronic kidney disease (CKD) is associated with poorer outcomes following percutaneous coronary intervention (PCI) with drug-eluting stents. Drug-eluting balloons are used for in-stent restenosis and selected ...

    Authors: Michael Jonas, Maayan Kagan, Gal Sella, Dan Haberman and Gil Chernin

    Citation: BMC Nephrology 2020 21:445

    Content type: Research article

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  42. Dyspepsia is a common disorder in kidney transplant recipients, and the risk of post-transplant complications is increased in candidates with upper gastrointestinal disease. We evaluated gastrointestinal lesio...

    Authors: Mehmet Usta, Alparslan Ersoy, Yavuz Ayar, Gökhan Ocakoğlu, Bilgehan Yuzbasioglu, Emrullah Düzgün Erdem and Omer Erdogan

    Citation: BMC Nephrology 2020 21:444

    Content type: Research article

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  43. Patients with end-stage kidney disease (ESKD) treated with hemodialysis (HD) experience many distressing symptoms. One frequently reported symptom is insomnia. There are unique issues about HD treatments and s...

    Authors: Mark Unruh, Daniel Cukor, Tessa Rue, Kashif Abad, Maria-Eleni Roumelioti, Susan M. McCurry, Patrick Heagerty and Rajnish Mehrotra

    Citation: BMC Nephrology 2020 21:443

    Content type: Study protocol

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  44. Although lupus nephritis (LN) is mostly characterized by glomerular involvement, tubular injury is indispensable in its pathogenesis and progression. The purpose of this study is to examine associations betwee...

    Authors: Huanhuan Zhu, Huiting Wan, Suyan Duan, Chengning Zhang, Qing Li, Simeng Liu, Lin Wu, Bo Zhang, Changying Xing and Yanggang Yuan

    Citation: BMC Nephrology 2020 21:442

    Content type: Research article

    Published on:

  45. Early identification and treatment of kidney transplant rejection episodes is vital to limit loss of function and prolong the life of the transplanted kidney and recipient. Current practice depends on detectin...

    Authors: Amy Riddell, John Kirkwood, Miranda Smallwood, Paul Winyard, Beatrice Knight, Lidia Romanczuk, Angela Shore and Mark Gilchrist

    Citation: BMC Nephrology 2020 21:441

    Content type: Research article

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  46. HIV infection affects multiple organs and the kidney is a common target making renal disease, one of the recognized complications. Microalbuminuria represents an early, important marker of kidney damage in sev...

    Authors: Thomas Kiggundu, Robert Kalyesubula, Irene Andia-Biraro, Gyaviira Makanga and Pauline Byakika-Kibwika

    Citation: BMC Nephrology 2020 21:440

    Content type: Research article

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  47. Transplant renal artery stenosis (TRAS) is a serious vascular complication that occurs after renal transplantation and can result in hypertension, renal functional impairment, and graft loss. Endovascular trea...

    Authors: Xiangjun Dong, Yingliang Wang, Huimin Liang, Chuansheng Zheng, Hui Zhao, Hong yao Hu, Xi Long and Yangbo Su

    Citation: BMC Nephrology 2020 21:439

    Content type: Case report

    Published on:

  48. Phase angle (PA), measured by bioelectrical impedance analysis (BIA) has been studied as indicator of nutritional status or muscle function in hemodialysis (HD) patients. It remains unclear if the phase angle ...

    Authors: Masakazu Saitoh, Masumi Ogawa, Hisae Kondo, Kiichi Suga, Tetsuya Takahashi, Haruki Itoh and Yoichiro Tabata

    Citation: BMC Nephrology 2020 21:438

    Content type: Research article

    Published on:

  49. Peritoneal dialysis (PD) has been used occasionally in extremely-low-birth-weight (ELBW) infants with acute kidney injury (AKI). This study aimed to evaluate the clinical characteristics and outcomes of ELBW i...

    Authors: Jihyun Noh, Chae Young Kim, Euiseok Jung, Joo Hoon Lee, Young-Seo Park, Byong Sop Lee, Ellen Ai-Rhan Kim and Ki-Soo Kim

    Citation: BMC Nephrology 2020 21:437

    Content type: Research article

    Published on:

  50. Individuals of African descent are at higher risk of developing kidney disease than their European counterparts, and HIV infection is associated with increased risk of nephropathy. Despite a safe renal profile...

    Authors: Muzamil O. Hassan, Raquel Duarte, Victor O. Mabayoje, Caroline Dickens, Akeem O. Lasisi and Saraladevi Naicker

    Citation: BMC Nephrology 2020 21:436

    Content type: Study protocol

    Published on:

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