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  1. Chronic kidney disease (CKD), including nephrotic syndrome, is a major cause of cardiovascular morbidity and mortality. The literature indicates that CKD is associated with profound lipid disorders due to the ...

    Authors: Hardik Ghelani, Valentina Razmovski-Naumovski, Dennis Chang and Srinivas Nammi
    Citation: BMC Nephrology 2019 20:431
  2. Dialysis patients experience high rates of foot ulceration. Although risk factors for ulceration have been extensively studied in patients with diabetes, there is limited high-quality, longitudinal evidence in...

    Authors: Michelle R. Kaminski, Katrina A. Lambert, Anita Raspovic, Lawrence P. McMahon, Bircan Erbas, Peter F. Mount, Peter G. Kerr and Karl B. Landorf
    Citation: BMC Nephrology 2019 20:423
  3. In this single-center, retrospective observational study, we assessed the long-term patency of vascular access (VA) after first VA placement to uncover independent risk factors associated with VA patency in As...

    Authors: Seonjeong Jeong, Hyunwook Kwon, Jai Won Chang, Min-Ju Kim, Khaliun Ganbold, Youngjin Han, Tae-Won Kwon and Yong-Pil Cho
    Citation: BMC Nephrology 2019 20:422
  4. Dietary acid load has been suggested to mediate the progression of chronic kidney disease (CKD). However, it is unclear what kinds of foods are actually associated with dietary acid load in patients with CKD. ...

    Authors: Koji Toba, Michihiro Hosojima, Hideyuki Kabasawa, Shoji Kuwahara, Toshiko Murayama, Keiko Yamamoto-Kabasawa, Ryohei Kaseda, Eri Wada, Reiko Watanabe, Naohito Tanabe, Yoshiki Suzuki, Ichiei Narita and Akihiko Saito
    Citation: BMC Nephrology 2019 20:421
  5. Acute kidney injury (AKI) is still characterized by a high mortality rate. While most patients with AKI are admitted in conventional medical units, current available data are still obtained from studies design...

    Authors: Jamal Bamoulid, Hélène Philippot, Amir Kazory, Maria Yannaraki, Thomas Crepin, Bérengère Vivet, Nadège Devillard, Caroline Roubiou, Catherine Bresson-Vautrin, Jean-Marc Chalopin, Cécile Courivaud and Didier Ducloux
    Citation: BMC Nephrology 2019 20:419
  6. IgG4-related disease, described around the years 2000 as a form of autoimmune pancreatitis, is now increasingly accepted as a systemic syndrome. The diagnosis is based on both comprehensive and organ-specific ...

    Authors: Giorgia Comai, Vania Cuna, Benedetta Fabbrizio, Elena Sabattini, Ornella Leone, Francesco Tondolo, Andrea Angeletti, Maria Cappuccilli, Rocco Liguori and Gaetano La Manna
    Citation: BMC Nephrology 2019 20:418
  7. Membranoproliferative glomerulonephritis (MPGN) is an uncommon cause of end stage kidney disease (ESKD) and the clinical outcomes of patients with MPGN who commence kidney replacement therapy have not been com...

    Authors: Gregory J. Wilson, Yeoungjee Cho, Armando Teixiera-Pinto, Nicole Isbel, Scott Campbell, Carmel Hawley and David W. Johnson
    Citation: BMC Nephrology 2019 20:417
  8. Chronic kidney disease (CKD) is a global public health problem, exhibiting sharp increases in incidence, prevalence, and attributable morbidity and mortality. There is a critical need to better understand the ...

    Authors: Keith C. Norris, O. Kenrik Duru, Radica Z. Alicic, Kenn B. Daratha, Susanne B. Nicholas, Sterling M. McPherson, Douglas S. Bell, Jenny I. Shen, Cami R. Jones, Tannaz Moin, Amy D. Waterman, Joshua J. Neumiller, Roberto B. Vargas, Alex A. T. Bui, Carol M. Mangione and Katherine R. Tuttle
    Citation: BMC Nephrology 2019 20:416
  9. Following publication of the original article [1], the authors reported errors in the presentation of Tables 2, 4 and 5.

    Authors: Shubhadeep D. Sinha, Vamsi Krishna Bandi, Bala Reddy Bheemareddy, Pankaj Thakur, Sreenivasa Chary, Kalpana Mehta, Vikranth Reddy Pinnamareddy, Rajendra Pandey, Subhramanyam Sreepada and Santosh Durugkar
    Citation: BMC Nephrology 2019 20:415

    The original article was published in BMC Nephrology 2019 20:90

  10. Secondary hyperparathyroidism is a common complication in patients with chronic kidney disease that requires vigilant treatment due to its high mortality rate. Pharmacologic therapy is recommended as an initia...

    Authors: Ho-Ryun Won, Jae Yoon Kang, In Ho Lee, Jin-Man Kim, Jae Won Chang and Bon Seok Koo
    Citation: BMC Nephrology 2019 20:414
  11. Desmopressin is used to reduce bleeding after kidney biopsy but evidence supporting its use is weak, especially in patients with elevated creatinine. The present study was undertaken to evaluate efficacy of de...

    Authors: Ambarish Athavale, Hemant Kulkarni, Cagil D. Arslan and Peter Hart
    Citation: BMC Nephrology 2019 20:413
  12. Inflammaging is a persistent, low−grade, sterile, nonresolving inflammatory state, associated with the senescence of the immune system. Such condition downregulates both innate and adaptive immune responses du...

    Authors: Vincenzo Sepe, Marilena Gregorini, Teresa Rampino, Pasquale Esposito, Rosanna Coppo, Francesco Galli and Carmelo Libetta
    Citation: BMC Nephrology 2019 20:412
  13. Peritoneal fibrosis is the most common complication of peritoneal dialysis, but there is currently no effective treatment. We previously reported that suramin pretreatment prevents the development of peritonea...

    Authors: Chongxiang Xiong, Na Liu, Xiaofei Shao, Sairah Sharif, Hequn Zou and Shougang Zhuang
    Citation: BMC Nephrology 2019 20:411
  14. IgA nephropathy (IgAN) involves mesangial matrix expansion, but the proteomic composition of this matrix is unknown. The present study aimed to characterize changes in extracellular matrix in IgAN.

    Authors: Flavia Teodora Ioana Paunas, Kenneth Finne, Sabine Leh, Tarig Al-Hadi Osman, Hans-Peter Marti, Frode Berven and Bjørn Egil Vikse
    Citation: BMC Nephrology 2019 20:410
  15. Delayed graft function (DGF) is an important complication of kidney transplantation and can be diagnosed according to different definitions. DGF has been suggested to be associated with the long-term outcome o...

    Authors: Xiao-jun Hu, Jin Zheng, Yang Li, Xiao-hui Tian, Pu-xun Tian, He-li Xiang, Xiao-ming Pan, Chen-guang Ding, Xiao-ming Ding and Wu-jun Xue
    Citation: BMC Nephrology 2019 20:409
  16. Nonadherence to medications by patients requiring hemodialysis (HD) leads to unfavorable clinical outcomes. Limited data exist to demonstrate the effect of incorporating patient-centered interventions using co...

    Authors: Sherine Ismail, Abrar Al-Subhi, Eman Youssif, Medhat Ahmed, Abdullah Almalki, Diane L. Seger, Andrew C. Seger and Earl Cook
    Citation: BMC Nephrology 2019 20:408
  17. Following a substantial increase in the utilization of extracorporeal membrane oxygenation (ECMO) during the last decade, its associated benefits and complications, including acute kidney injury have become mo...

    Authors: Kianoush Kashani and Marlies Ostermann
    Citation: BMC Nephrology 2019 20:404
  18. Kidney disease is a serious manifestation of systemic amyloidosis and a major cause of morbidity and mortality. Tuberculosis (TB) occurs up to 27 times more commonly in human immunodeficiency virus (HIV) infec...

    Authors: Muhammed Hassen, William Bates and Mohammed Rafique Moosa
    Citation: BMC Nephrology 2019 20:406
  19. Persistent hyperparathyroidism after kidney transplantation has been associated with adverse outcomes. Parathyroidectomy is the definitive treatment approach, but the success of parathyroidectomy relies on the...

    Authors: Jun Yang, Jun Zhang, Jian-li Bi, Wan-wen Weng and Meng-jie Dong
    Citation: BMC Nephrology 2019 20:405
  20. The renal function of the remaining kidney in living donors recovers up to 60~70% of pre-donation estimated-glomerular filtration rate (eGFR) by compensatory hypertrophy. However, the degree of this hypertroph...

    Authors: Sho Nishida, Yuji Hidaka, Mariko Toyoda, Kohei Kinoshita, Kosuke Tanaka, Chiaki Kawabata, Satoshi Hamanoue, Akito Inadome, Hiroshi Yokomizo, Asami Takeda, Soichi Uekihara and Shigeyoshi Yamanaga
    Citation: BMC Nephrology 2019 20:403
  21. Patients with chronic kidney diseases (CKD) on haemodialysis (HD) have high morbidity and mortality rates, which are also due to the inherent risks associated with nephropathy. Non-adherence (NA) to the differ...

    Authors: Lianna G. G. Dantas, Mário de Seixas Rocha, José Andrade Moura Junior, Edson Luiz Paschoalin, Sandra R. K. P. Paschoalin and Constança M. Sampaio Cruz
    Citation: BMC Nephrology 2019 20:402
  22. Cystinosis is an autosomal recessive lysosomal storage disorder characterized by accumulation of cystine in lysosomes throughout the body. Cystinosis is caused by mutations in the CTNS gene that encodes the lysos...

    Authors: Svetlana Papizh, Victoria Serzhanova, Alexandra Filatova, Mikhail Skoblov, Vyacheslav Tabakov, Lambert van den Heuvel, Elena Levtchenko and Larisa Prikhodina
    Citation: BMC Nephrology 2019 20:400
  23. Occurrence of cardiovascular disease (CVD) in the setting of chronic kidney disease (CKD) can be described as a “cruel alliance”, with CVD responsible for about half of all deaths among CKD patients. Chronic k...

    Authors: S. O. Oguntola, M. O. Hassan, R. Duarte, A. Vachiat, P. Manga and S. Naicker
    Citation: BMC Nephrology 2019 20:399
  24. Patients with chronic kidney disease (CKD) have a high prevalence of cardiovascular diseases, which often lead to physical inactivity that correlates with CKD exacerbation. The benefits of regular exercise to ...

    Authors: Lijun Zhang, Yangyang Wang, Lianlian Xiong, Yanfang Luo, Zhijun Huang and Bin Yi
    Citation: BMC Nephrology 2019 20:398
  25. Elevated serum phosphorus concentrations are common among maintenance hemodialysis patients. Protein is a major source of dietary phosphate, but restriction of protein intake can result in hypoalbuminemia and ...

    Authors: Kamyar Kalantar-Zadeh, Linda H. Ficociello, Vidhya Parameswaran, Nicolaos V. Athienites, Claudy Mullon, Robert J. Kossmann and Daniel W. Coyne
    Citation: BMC Nephrology 2019 20:396
  26. Major Depressive Disorder (MDD) can lead to adverse cardiovascular outcomes in patients with chronic kidney disease (CKD). Although one of the proposed mechanisms is heightened platelet activation, effects of ...

    Authors: Nishank Jain, Fei Wan, Monica Kothari, Anuoluwapo Adelodun, Jerry Ware, Ravi Sarode and S. Susan Hedayati
    Citation: BMC Nephrology 2019 20:395
  27. Sebaceous carcinoma is a rare but progressive malignant skin cancer, and the incidence is approximately five times higher in post-transplant patients than in people who have not received kidney transplants. Se...

    Authors: Masahiro Tomonari, Mariko Shimada, Yasuyuki Nakada, Izumi Yamamoto, Munenari Itoh, Yusuke Koike, Akimitsu Kobayashi, Jun Miki, Hiroki Yamada, Takahiro Kimura, Shinya Saito, Kokichi Sugano, Shigeki Sekine, Hiroyasu Yamamoto, Akihiko Asahina and Takashi Yokoo
    Citation: BMC Nephrology 2019 20:394
  28. Preliminary studies have shown the potential use of salivary creatinine concentration in the diagnosis of chronic kidney disease (CKD). For saliva to replace serum as a diagnostic tool, studies must be done to...

    Authors: Dada Oluwaseyi Temilola, Karla Bezuidenhout, Rajiv Timothy Erasmus, Lawrence Stephen, Mogamat Razeen Davids and Haly Holmes
    Citation: BMC Nephrology 2019 20:387
  29. Diabetic nephropathy is a global common cause of chronic kidney disease and end-stage renal disease. A lot of research has been conducted in biomedical sciences, which has enhanced understanding of the pathoph...

    Authors: Eduardo De la Cruz-Cano, Cristina del C. Jiménez-González, Vicente Morales-García, Conny Pineda-Pérez, Juan G. Tejas-Juárez, Francisco J. Rendón-Gandarilla, Silvia Jiménez-Morales and José A. Díaz-Gandarilla
    Citation: BMC Nephrology 2019 20:393
  30. Online hemodiafiltration (OL-HDF) is associated with better removal of both small and middle molecules and might improve survival compared to conventional hemodialysis (HD). Nevertheless, hemodiafiltration (HD...

    Authors: Charles Cuvelier, Michel Tintillier, Gabriela Migali, Charlotte Van Ende and Jean-Michel Pochet
    Citation: BMC Nephrology 2019 20:392
  31. Cell-free deoxyribonucleic acid DNA (cf-DNA) in urine is promising due to the advantage of urine as an easily obtained and non-invasive sample source over tissue and blood. In clinical practice, it is importan...

    Authors: Chia-Chu Chang, Ping-Fang Chiu, Chia-Lin Wu, Cheng-Ling Kuo, Ching-Shan Huang, Chin-San Liu and Ching-Hui Huang
    Citation: BMC Nephrology 2019 20:391
  32. Neuropsychiatric conditions such as depression, delirium and cognitive impairment are common in patients with end-stage kidney disease (ESKD) and individuals suffering from ESKD are more likely to commit suici...

    Authors: Pierre Antoine Brown, Peter O. Magner, Swapnil Hiremath and Edward G. Clark
    Citation: BMC Nephrology 2019 20:390
  33. Some people who are receiving dialysis treatment have virus infection such as hepatitis B, hepatitis C and/or HIV that is present in their blood. These infections can be transmitted to other patients if blood ...

    Authors: Elizabeth Garthwaite, Veena Reddy, Sam Douthwaite, Simon Lines, Kay Tyerman and James Eccles
    Citation: BMC Nephrology 2019 20:388
  34. Liddle syndrome is a monogenic disease with autosomal dominant inheritance. Basic characteristics of this disease are hypertension, reduced concentration of aldosterone and renin activity, as well as increased...

    Authors: Anastasiya A. Kozina, Tatiana A. Trofimova, Elena G. Okuneva, Natalia V. Baryshnikova, Varvara A. Obuhova, Anna Yu. Krasnenko, Kirill Yu. Tsukanov, Olesya I. Klimchuk, Ekaterina I. Surkova, Peter A. Shatalov and Valery V. Ilinsky
    Citation: BMC Nephrology 2019 20:389
  35. Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) often develop hypertension in childhood or early adulthood. Although this could result in left ventricular hypertrophy (LVH), a major risk fac...

    Authors: Huanwen Chen, Terry Watnick, Susie N. Hong, Barry Daly, Yongfang Li and Stephen L. Seliger
    Citation: BMC Nephrology 2019 20:386
  36. Conservative management, an approach to treating end-stage kidney disease without dialysis, while generally associated with shorter life expectancy than treatment with dialysis, is associated with fewer hospit...

    Authors: Melissa W. Wachterman, Tarikwa Leveille, Nancy L. Keating, Steven R. Simon, Sushrut S. Waikar and Barbara Bokhour
    Citation: BMC Nephrology 2019 20:385
  37. Hemorrhagic fever with renal syndrome (HFRS) is an acute disease caused by hantavirus infection and is clinically characterized by fever, various hemorrhagic manifestations and transient renal and hepatic dysf...

    Authors: Li Zhang, Qing-shan Ma, Yan Zhang, Bai-chao Sun and Leng-yue Zhao
    Citation: BMC Nephrology 2019 20:383
  38. Background: The pathological findings of tonsils in IgA nephropathy include the expansion of T-cell nodules around lymphoid follicles and abnormal reticulation of the crypt epithelium in contrast to chronic to...

    Authors: Takuji Enya, Tomoki Miyazawa, Kohei Miyazaki, Rina Oshima, Yuichi Morimoto, Mitsuru Okada, Tsukasa Takemura and Keisuke Sugimoto
    Citation: BMC Nephrology 2019 20:381

    The Correction to this article has been published in BMC Nephrology 2024 25:110

  39. Cancer in patients with chronic kidney disease (CKD) is an added burden to their overall morbidity and mortality. Cancer can be a cause or an effect of CKD. In CKD patients, a better understanding of cancer di...

    Authors: Rajkumar Chinnadurai, Emma Flanagan, Gordon C. Jayson and Philip A. Kalra
    Citation: BMC Nephrology 2019 20:380
  40. The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health sys...

    Authors: Francis F. Furia, Jacqueline Shoo, Paschal J. Ruggajo, Kajiru Kilonzo, Gopal Basu, Karen Yeates, Santosh Varughese, Einar Svarstad and Onesmo Kisanga
    Citation: BMC Nephrology 2019 20:378
  41. Lipofuscin deposition is a characteristic manifestation of aging. There is very limited literature in humans and in animals describing these deposits in native kidneys. Overall, it is thought to be non-pathoge...

    Authors: Vivian W. Y. Leung, Sarah-Jeanne Pilon, Pierre O. Fiset and Shaifali Sandal
    Citation: BMC Nephrology 2019 20:376
  42. TAFRO syndrome is a systemic inflammatory disorder that manifests as thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis (R), and organomegaly (O). Renal dysfunction is frequently complicated wit...

    Authors: Yoshikuni Nagayama, Mizuki Yamano, Motoka Yagame, Tomoyuki Nariyama, Mikiko Takahashi, Masashi Kawamoto and Katsuyuki Matsui
    Citation: BMC Nephrology 2019 20:375
  43. Heavy metal poisoning can cause debilitating illness if left untreated, and its management in anuric patients poses challenges. Literature with which to guide clinical practice in this area is rather scattered.

    Authors: Chun-Yuan Hsiao, Chip Gresham and Mark R. Marshall
    Citation: BMC Nephrology 2019 20:374
  44. Medication non-adherence is a risk factor for acute kidney transplant rejection. The association of non-adherence with short-term allograft loss in patients who develop acute rejection and are subsequently tre...

    Authors: Ahmed Al-Sheyyab, Laura Binari, Mohammed Shwetar, Everly Ramos, Meghan E. Kapp, Stefanie Bala, Nikita Wilson, Rachel C. Forbes, J. Harold Helderman, Khaled Abdel-Kader and Beatrice P. Concepcion
    Citation: BMC Nephrology 2019 20:373

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