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  1. Content type: Research article

    The objective was to investigate the association between renal structural parameters and renal function. The structural parameters were renal cortical volume, total renal volume, number of glomeruli, and total...

    Authors: Anders B Lødrup, Kristian Karstoft, Thomas H Dissing, Jens R Nyengaard and Michael Pedersen

    Citation: BMC Nephrology 2008 9:18

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  2. Content type: Study protocol

    There is evidence that renal transplant recipients have accelerated atherosclerosis manifest by increased cardiovascular morbidity and mortality. The high incidence of atherosclerosis is, in part, related to i...

    Authors: Robert G Fassett, Helen Healy, Ritza Driver, Iain K Robertson, Dominic P Geraghty, James E Sharman and Jeff S Coombes

    Citation: BMC Nephrology 2008 9:17

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  3. Content type: Research article

    Guidelines for the management of anaemia in patients with chronic kidney disease (CKD) recommend a minimal haemoglobin (Hb) target of 11 g/dL. Recent surveys indicate that this requirement is not met in many p...

    Authors: Claudine M Mathieu, Daniel Teta, Nathalie Lötscher, Dela Golshayan, Luca Gabutti, Denes Kiss, Pierre-Yves Martin and Michel Burnier

    Citation: BMC Nephrology 2008 9:16

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  4. Content type: Research article

    In hemodialysis, extracorporeal blood flow (Qb) recommendation is 300–500 mL/min. To achieve the best Qb, we based our prescription on dynamic arterial line pressure (DALP).

    Authors: Franklin G Mora-Bravo, Alfonso Mariscal, Juan P Herrera–Felix, Salvador Magaña, Guadalupe De-La-Cruz, Nelly Flores, Laura Rosales, Martha Franco and Héctor Pérez-Grovas

    Citation: BMC Nephrology 2008 9:15

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  5. Content type: Research article

    The study examines differences regarding quality of life (QoL), mental health and illness beliefs between in-centre haemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD/PD) patients. Differen...

    Authors: M Ginieri-Coccossis, P Theofilou, C Synodinou, V Tomaras and C Soldatos

    Citation: BMC Nephrology 2008 9:14

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  6. Content type: Research article

    Focal and segmental glomerulosclerosis (FSGS) is the most common histologic pattern of renal injury seen in adults with idiopathic proteinuria. Homozygous or compound heterozygous mutations in the podocin gene NP...

    Authors: Stephen J Tonna, Alexander Needham, Krishna Polu, Andrea Uscinski, Gerald B Appel, Ronald J Falk, Avi Katz, Salah Al-Waheeb, Bernard S Kaplan, George Jerums, Judy Savige, Jennifer Harmon, Kang Zhang, Gary C Curhan and Martin R Pollak

    Citation: BMC Nephrology 2008 9:13

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  7. Content type: Research article

    Familial hypomagnesaemia with hypercalciuria and nephrocalcinosis (FHHNC) is an autosomal recessive disorder of renal calcium and magnesium wasting frequently complicated by progressive chronic renal failure i...

    Authors: Geeta Hampson, Martin A Konrad and John Scoble

    Citation: BMC Nephrology 2008 9:12

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  8. Content type: Research article

    Monoclonal free light chains (FLCs) frequently cause rapidly progressive renal failure in patients with multiple myeloma. Immunoassays which provide quantitative measurement of FLCs in serum, have now been ado...

    Authors: Colin A Hutchison, Tim Plant, Mark Drayson, Paul Cockwell, Melpomeni Kountouri, Kolitha Basnayake, Stephen Harding, Arthur R Bradwell and Graham Mead

    Citation: BMC Nephrology 2008 9:11

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  9. Content type: Research article

    Autosomal Dominant Polycystic Kidney Disease (ADPKD) is characterized by the formation of multiple fluid-filled cysts that destroy the kidney architecture resulting in end-stage renal failure. Mutations in genes

    Authors: Kyriacos N Felekkis, Panayiota Koupepidou, Evdokia Kastanos, Ralph Witzgall, Chang-Xi Bai, Li Li, Leonidas Tsiokas, Norbert Gretz and Constantinos Deltas

    Citation: BMC Nephrology 2008 9:10

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  10. Content type: Research article

    Prior studies using creatinine-based estimated glomerular filtration rate (eGFR) have found limited associations between kidney function and markers of inflammation. Using eGFR and cystatin C, a novel marker o...

    Authors: Christopher Keller, Ronit Katz, Mary Cushman, Linda F Fried and Michael Shlipak

    Citation: BMC Nephrology 2008 9:9

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  11. Content type: Study protocol

    The main hypothesis of this study is that Oxpentifylline administration will effectively treat erythropoietin- or darbepoietin-resistant anaemia in chronic kidney disease patients.

    Authors: David Wayne Johnson, Carmel Mary Hawley, Brenda Rosser, Elaine Beller, Charles Thompson, Robert G Fassett, Paolo Ferrari, Stephen MacDonald, Eugenie Pedagogos and Alan Cass

    Citation: BMC Nephrology 2008 9:8

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  12. Content type: Research article

    Selenoproteins contain selenocysteine (Sec), commonly considered the 21st genetically encoded amino acid. Many selenoproteins, such as the glutathione peroxidases and thioredoxin reductases, protect cells against...

    Authors: Marsha N Blauwkamp, Jingcheng Yu, MaryLee A Schin, Kathleen A Burke, Marla J Berry, Bradley A Carlson, Frank C Brosius III and Ronald J Koenig

    Citation: BMC Nephrology 2008 9:7

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  13. Content type: Research article

    Concern lingers that dialysis therapy at for-profit (versus not-for-profit) hemodialysis facilities in the United States may be associated with higher mortality, even though 4 of every 5 contemporary dialysis ...

    Authors: Robert N Foley, Qiao Fan, Jiannong Liu, David T Gilbertson, Eric D Weinhandl, Shu-Cheng Chen and Allan J Collins

    Citation: BMC Nephrology 2008 9:6

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  14. Content type: Research article

    Administrative claims are a rich source of information for epidemiological and health services research; however, the ability to accurately capture specific diseases or complications using claims data has been...

    Authors: Alisa M Shea, Lesley H Curtis, Lynda A Szczech and Kevin A Schulman

    Citation: BMC Nephrology 2008 9:5

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  15. Content type: Study protocol

    There is evidence that dyslipidemia is associated with chronic kidney disease (CKD). Experimental studies have established that lipids are damaging to the kidney and animal intervention studies show statins at...

    Authors: Robert G Fassett, Madeleine J Ball, Iain K Robertson, Dominic P Geraghty and Jeff S Coombes

    Citation: BMC Nephrology 2008 9:4

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  16. Content type: Research article

    Cardiovascular events are the leading cause of death in end stage renal disease (ESRD). Adherence to phosphate binding medication plays a vital role in reducing serum phosphorus and associated cardiovascular r...

    Authors: Christina Karamanidou, Jane Clatworthy, John Weinman and Rob Horne

    Citation: BMC Nephrology 2008 9:2

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  17. Content type: Research article

    An ad hoc peer-review committee was jointly appointed by Drug Authorities and Industry in Germany, Austria and Switzerland in 1999/2000 to review the evidence for a causal relation between phenacetin-free anal...

    Authors: Fokke J van der Woude, Lothar AJ Heinemann, Helmut Graf, Michael Lewis, Sabine Moehner, Anita Assmann and Doerthe Kühl-Habich

    Citation: BMC Nephrology 2007 8:15

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  18. Content type: Research article

    The aim of this study is to evaluate the association between acute serum creatinine changes in acute renal failure (ARF), before specialized treatment begins, and in-hospital mortality, recovery of renal funct...

    Authors: Jose Ramon Perez-Valdivieso, Maira Bes-Rastrollo, Pablo Monedero, Jokin de Irala and Francisco Javier Lavilla

    Citation: BMC Nephrology 2007 8:14

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  19. Content type: Study protocol

    Currently there is no effective treatment available to retard cyst growth and to prevent the progression to end-stage renal failure in patients with autosomal dominant polycystic kidney disease (ADPKD). Eviden...

    Authors: Andreas L Serra, Andreas D Kistler, Diane Poster, Marian Struker, Rudolf P Wüthrich, Dominik Weishaupt and Frank Tschirch

    Citation: BMC Nephrology 2007 8:13

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  20. Content type: Research article

    Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disease with few treatment options other than renal replacement therapy. p21, a cyclin kinase inhibitor which has pleiotropic effects on...

    Authors: Jin-Young Park, William E Schutzer, Jessie N Lindsley, Susan P Bagby, Terry T Oyama, Sharon Anderson and Robert H Weiss

    Citation: BMC Nephrology 2007 8:12

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  21. Content type: Research article

    Idiopathic membranous nephropathy (IMN) is one of the most common causes of primary nephrotic syndrome in adults. However, it is a relatively rare entity in the pediatric population and there is a paucity of d...

    Authors: Ashton Chen, Rachel Frank, Suzanne Vento, Virginia Crosby, Manju Chandra, Bernard Gauthier, Elsa Valderrama and Howard Trachtman

    Citation: BMC Nephrology 2007 8:11

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  22. Content type: Research article

    Systemic hypertension often accompanies chronic renal failure and can accelerate its progression to end-stage renal disease (ESRD). Adjunctive moxonidine appeared to have benefits versus adjunctive nitrendipin...

    Authors: Kavi J Littlewood, Wolfgang Greiner, Dominique Baum and York Zoellner

    Citation: BMC Nephrology 2007 8:9

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  23. Content type: Case report

    Fibrillary glomerulonephritis is a rare cause of progressive renal dysfunction, often leading to the need for dialysis within a few years. The role of immunosuppressive treatment is still uncertain although th...

    Authors: Muhammad M Javaid, Helen Denley and Senyo Tagboto

    Citation: BMC Nephrology 2007 8:7

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  24. Content type: Case report

    Imatinib is a tyrosine-kinase inhibitor; for which there is limited information regarding its effects on AIDS Kaposi's sarcoma and none in patients with transplant-associated Kaposi's sarcoma. Sirolimus, an im...

    Authors: Patricia Volkow, Juan W Zinser and Ricardo Correa-Rotter

    Citation: BMC Nephrology 2007 8:6

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  25. Content type: Case report

    Thrombocytopenia and absent radius syndrome (TAR) is a rare genetic disorder. It is an autosomal recessive disorder characterised by radial aplasia and thrombocytopenia that may have additional anomalies. We r...

    Authors: Riaz Ahmad

    Citation: BMC Nephrology 2007 8:5

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  26. Content type: Study protocol

    It is uncertain whether patients with renal vascular disease will have renal or mortality benefit from re-establishing renal blood flow with renal revascularization procedures. The RAVE study will compare rena...

    Authors: Sheldon W Tobe, M Atri, N Perkins, R Pugash and Chaim M Bell

    Citation: BMC Nephrology 2007 8:4

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  27. Content type: Research article

    Mercuric chloride (HgCl2) induces an autoimmune nephritis in the Brown Norway (BN) rats characterized by anti-glomerular basement membrane antibodies (anti-GBM Ab) deposition, proteinuria and a severe interstitia...

    Authors: María M Escribese, Elisa Conde, Ana Martín, David Sáenz-Morales, David Sancho, Guillermo Pérez de Lema, Javier Lucio-Cazaña, Francisco Sánchez-Madrid, María L García-Bermejo and Francisco M Mampaso

    Citation: BMC Nephrology 2007 8:3

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  28. Content type: Research article

    The prevalences and risk factors of microalbuminuria are not full described among black African diabetic patients. This study aimed at determining the prevalence of microalbuminuria among African diabetes pati...

    Authors: Janet Joy Kachuchuru Lutale, Hrafnkell Thordarson, Zulfiqarali Gulam Abbas and Kåre Vetvik

    Citation: BMC Nephrology 2007 8:2

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  29. Content type: Research article

    This study used a cross sectional survey to examine the effect of gender, age, and geographical location on the population prevalence of renal replacement therapy (RRT) provision in Wales.

    Authors: Hugo C van Woerden, Jane Wilkinson, Martin Heaven and Jason Merrifield

    Citation: BMC Nephrology 2007 8:1

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  30. Content type: Case report

    Hornet stings are generally associated with local and occasionally anaphylactic reactions. Rarely systemic complications like acute renal failure can occur following multiple stings. Renal failure is usually d...

    Authors: Aman Sharma, Ajay Wanchu, V Mahesha, V Sakhuja, Pradeep Bambery and Surjit Singh

    Citation: BMC Nephrology 2006 7:18

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  31. Content type: Research article

    Small vessel vasculitides are known to follow a devastating course towards end-stage renal disease, unless treated with immunosuppressive regiments. We investigated the value of clinical, histological and immu...

    Authors: Efstathios Alexopoulos, Lazaros Gionanlis, Ekaterini Papayianni, Elizabeth Kokolina, Maria Leontsini and Dimitrios Memmos

    Citation: BMC Nephrology 2006 7:16

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  32. Content type: Research article

    The Renin-Angiotensin system (RAS) is a key regulator of both blood pressure and kidney functions and their interaction. In such a situation, genetic variability in the genes of different components of RAS is ...

    Authors: Gaurav Tripathi, Poonam Dharmani, Faisal Khan, RK Sharma, Vinod Pandirikkal Baburajan and Suraksha Agrawal

    Citation: BMC Nephrology 2006 7:15

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  33. Content type: Research article

    Previous studies have shown that in male rats, exposure to maternal protein restriction either in utero or whilst suckling can have profound effects on both longevity and kidney telomere lengths. This study monit...

    Authors: Clive J Petry, Bridget J Jennings, Lynwen A James, Charles N Hales and Susan E Ozanne

    Citation: BMC Nephrology 2006 7:14

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  34. Content type: Research article

    Due to its strong intra- and inter-individual variability, predicting the ideal erythropoietin dose is a difficult task. The aim of this study was to re-evaluate the impact of the main parameters known to infl...

    Authors: Luca Gabutti, Nathalie Lötscher, Josephine Bianda, Claudio Marone, Giorgio Mombelli and Michel Burnier

    Citation: BMC Nephrology 2006 7:13

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  35. Content type: Research article

    Previous studies have linked smaller kidney dimensions to increased blood pressure. However, patients with Balkan Endemic Nephropathy (BEN), whose kidneys shrink during the course of the disease, do not manife...

    Authors: Plamen S Dimitrov, Valeri A Simeonov, Svetlana D Tsolova, Angel G Bonev, Rossitza B Georgieva and Wilfried J Karmaus

    Citation: BMC Nephrology 2006 7:12

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  36. Content type: Research article

    Medicare beneficiaries without prescription drug coverage consistently fill fewer prescriptions than beneficiaries with some form of drug coverage due to cost. ESRD patients, who are disproportionately poor an...

    Authors: Anisa I Nayeem and Glenn M Chertow

    Citation: BMC Nephrology 2006 7:11

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  37. Content type: Case report

    Advancements in immunosuppressive therapy have significantly improved patient and graft survival following renal transplantation. This is paralleled by an increasing occurrence of posttransplantation malignancy.

    Authors: Roland Schmitt, Ute Kettritz, Friedrich C Luft and Ralph Kettritz

    Citation: BMC Nephrology 2006 7:9

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  38. Content type: Study protocol

    Many patients with end-stage renal disease use a central venous catheter for hemodialysis access. A large majority of these catheters malfunction within one year of insertion, with up to two-thirds due to thro...

    Authors: Brenda R Hemmelgarn, Louise Moist, Rachel M Pilkey, Charmaine Lok, Marc Dorval, Paul YW Tam, Murray J Berall, Martine LeBlanc, Edwin B Toffelmire, Braden J Manns and Nairne Scott-Douglas

    Citation: BMC Nephrology 2006 7:8

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  39. Content type: Research article

    A reduction in the number of podocytes and podocyte density has been documented in the kidneys of patients with diabetes mellitus. Additional studies have shown that podocyte injury and loss occurs in both dia...

    Authors: Brian Siu, Jharna Saha, William E Smoyer, Kelli A Sullivan and Frank C Brosius III

    Citation: BMC Nephrology 2006 7:6

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  40. Content type: Research article

    Chelation therapy with sodium edetate (EDTA) improved renal function and slowed the progression of renal insufficiency in patients subjected to lead intoxication. This study was performed to identify the under...

    Authors: Chiara Foglieni, Alessandro Fulgenzi, Paolo Ticozzi, Fabio Pellegatta, Clara Sciorati, Daniela Belloni, Elisabetta Ferrero and Maria Elena Ferrero

    Citation: BMC Nephrology 2006 7:5

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  41. Content type: Research article

    Chronic kidney disease (CKD) has been linked to higher heart failure (HF) risk. Anemia is a common consequence of CKD, and recent evidence suggests that anemia is a risk factor for HF. The purpose of this stud...

    Authors: Jean-Christophe Luthi, W Dana Flanders, Michel Burnier, Bernard Burnand and William M McClellan

    Citation: BMC Nephrology 2006 7:3

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  42. Content type: Study protocol

    Nocturnal hemodialysis (NHD) is an alternative to conventional three times per week hemodialysis (CvHD) and has been reported to improve several health outcomes. To date, no randomized controlled trial (RCT) h...

    Authors: Michael Walsh, Braden J Manns, Scott Klarenbach, Robert Quinn, Marcello Tonelli and Bruce F Culleton

    Citation: BMC Nephrology 2006 7:2

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