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  1. Content type: Research article

    Lim1 is a homeobox gene that is essential for nephrogenesis. During metanephric kidney development, Lim1 is expressed in the nephric duct, ureteric buds, and the induced metanephric mesenchyme. Conditional ablat...

    Authors: You-Tzung Chen, Akio Kobayashi, Kin Ming Kwan, Randy L Johnson and Richard R Behringer

    Citation: BMC Nephrology 2006 7:1

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  2. Content type: Research article

    Despite multiple causes, Chronic Kidney Disease is commonly associated with proteinuria. A previous study on Non Obese Diabetic mice (NOD), which spontaneously develop type 1 diabetes, described histological a...

    Authors: Karen HS Wilson, Richard A McIndoe, Sarah Eckenrode, Laurence Morel, Anupam Agarwal, Byron P Croker and Jin-Xiong She

    Citation: BMC Nephrology 2005 6:17

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  3. Content type: Research article

    Crescentic nephritis is characterized by formation of cellular crescents that soon become fibrotic and result in irreversible damage, unless an effective immunosuppressive therapy is rapidly commenced. TGF-β1 is ...

    Authors: Dimitrios S Goumenos, Pantelitsa Kalliakmani, Sotiris Tsakas, Florentia Sotsiou and John G Vlachojannis

    Citation: BMC Nephrology 2005 6:16

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  4. Content type: Database

    IgA nephropathy (IgAN) or Berger's disease, is the most common glomerulonephritis in the world diagnosed in renal biopsied patients. The involvement of genetic factors in the pathogenesis of the IgAN is eviden...

    Authors: Francesco P Schena, Giuseppina Cerullo, Diletta D Torres, Francesco Scolari, Marina Foramitti, Antonio Amoroso, Doroti Pirulli, Jürgen Floege, Peter R Mertens, Klaus Zerres, Efstathios Alexopoulos, Dimitrios Kirmizis, Leopoldo Zelante, Luigi Bisceglia, Gian M Ghiggeri and Giovanni M Frascà

    Citation: BMC Nephrology 2005 6:14

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  5. Content type: Research article

    It has been established that hypothyroidism protects rats against renal ischemia and reperfusion (IR) oxidative damage. However, it is not clear if hypothyroidism is able to prevent protein tyrosine nitration,...

    Authors: Verónica M Tenorio-Velázquez, Diana Barrera, Martha Franco, Edilia Tapia, Rogelio Hernández-Pando, Omar Noel Medina-Campos and José Pedraza-Chaverri

    Citation: BMC Nephrology 2005 6:12

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  6. Content type: Research article

    The National Kidney Foundation has formulated clinical practice guidelines for patients with chronic kidney disease (K/DOQI). However, little is know about how many patients actually achieve these goals in a d...

    Authors: Oliver Lenz, Durga P Mekala, Daniel V Patel, Alessia Fornoni, David Metz and David Roth

    Citation: BMC Nephrology 2005 6:11

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  7. Content type: Study protocol

    The association between intake of non-phenacetin-containing analgesics and the occurrence of chronic renal failure is still controversially discussed. A new epidemiologic study was planned and conducted in Ger...

    Authors: Lothar AJ Heinemann, Edeltraut Garbe, Michael Lewis, Fokko van der Woude and Helmut Graf

    Citation: BMC Nephrology 2005 6:9

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  8. Content type: Research article

    The risk factors for progression of chronic kidney disease (CKD) in type 2 diabetes mellitus (DM) have not been fully elucidated. Although uncontrolled blood pressure (BP) is known to be deleterious, other fac...

    Authors: David J Leehey, Holly J Kramer, Tarek M Daoud, Maninder P Chatha and Majd A Isreb

    Citation: BMC Nephrology 2005 6:8

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  9. Content type: Case report

    Obesity is a growing health issue in the Western world. Obesity, as part of the metabolic syndrome adds to the morbidity and mortality. The incidence of diabetes and hypertension, two primary etiological facto...

    Authors: Sujata Agnani, Vidula T Vachharajani, Rohit Gupta, Naveen K Atray and Tushar J Vachharajani

    Citation: BMC Nephrology 2005 6:7

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  10. Content type: Research article

    In experimental models of diabetes mellitus, aggravation of renal injury by concomitant hypertension has been described. Inflammatory mechanisms contribute to renal damage in both diseases. We investigated whe...

    Authors: Andrea Hartner, Roland Veelken, Michael Wittmann, Nada Cordasic and Karl F Hilgers

    Citation: BMC Nephrology 2005 6:6

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  11. Content type: Research article

    Recombinant human erythropoietin (EPO) is used for the treatment of last stage renal anemia. A new EPO preparation was obtained in Cuba in order to make this treatment fully nationally available. The aim of th...

    Authors: Jorge F Pérez-Oliva, Martha Casanova-González, Idrian García-García, Pedro J Porrero-Martín, Carmen M Valenzuela-Silva, Tairí Hernández-Montero, Marcia Lagarde-Ampudia, Yuri Casanova-Kutsareva, Yisel Ávila-Albuerne, Alicia Vargas-Batista, Hailen Bobillo-López, Raúl Herrera-Valdés and Pedro A López-Saura

    Citation: BMC Nephrology 2005 6:5

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  12. Content type: Research article

    Potassium dichromate (K2Cr2O7)-induced nephrotoxicity is associated with oxidative and nitrosative stress. In this study we investigated the relation between the time course of the oxidative and nitrosative stres...

    Authors: José Pedraza-Chaverrí, Diana Barrera, Omar N Medina-Campos, Raymundo C Carvajal, Rogelio Hernández-Pando, Norma A Macías-Ruvalcaba, Perla D Maldonado, Marcos I Salcedo, Edilia Tapia, Liliana Saldívar, María E Castilla and María E Ibarra-Rubio

    Citation: BMC Nephrology 2005 6:4

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  13. Content type: Research article

    Essential hypertension is a common, polygenic, complex disorder resulting from interaction of several genes with each other and with environmental factors such as obesity, dietary salt intake, and alcohol cons...

    Authors: Adrian Mondry, Marie Loh, Pengbo Liu, Ai-Ling Zhu and Mato Nagel

    Citation: BMC Nephrology 2005 6:1

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  14. Content type: Case report

    The mortality rate among patients with infective endocarditis, especially associated with the presence of complications or coexisting conditions such as renal failure and the use of combined medical and surgic...

    Authors: Daisuke Koya, Kazuyuki Shibuya, Ryuichi Kikkawa and Masakazu Haneda

    Citation: BMC Nephrology 2004 5:18

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  15. Content type: Research article

    Lipoprotein lipase (LPL) has a central role in the catabolism of triglyceride-rich lipoproteins. The enzyme is anchored to the vascular endothelium through interaction with heparan sulphate proteoglycans and i...

    Authors: Birgit Näsström, Bernd Stegmayr, Gunilla Olivecrona and Thomas Olivecrona

    Citation: BMC Nephrology 2004 5:17

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  16. Content type: Research article

    Late referral to specialist nephrological care is associated with increased morbidity, mortality, and cost. Consequently, nephrologists' associations recommend early referral. The recommendations' effectivenes...

    Authors: Adrian Mondry, Ai-Ling Zhu, Marie Loh, Thuy D Vo and Kai Hahn

    Citation: BMC Nephrology 2004 5:16

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  17. Content type: Research article

    Renal artery stenosis (RAS) is a known cause of hypertension and ischemic nephropathy. Stenting of the artery is a valid approach, in spite of cases of unexpected adverse evolution of renal function.

    Authors: Giorgio Coen, Eleonora Moscaritolo, Carlo Catalano, Raffaella Lavini, Italo Nofroni, Giuseppe Ronga, Daniela Sardella, Alvaro Zaccaria and Rosario Cianci

    Citation: BMC Nephrology 2004 5:15

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  18. Content type: Study protocol

    Peritoneal dialysis (PD) is the preferred dialysis modality in children. Its major drawback is the limited technique survival due to infections and progressive ultrafiltration failure. Conventional PD solution...

    Authors: Barbara Nau, Claus P Schmitt, Margarida Almeida, Klaus Arbeiter, Gianluigi Ardissino, Klaus E Bonzel, Alberto Edefonti, Michel Fischbach, Karin Haluany, Joachim Misselwitz, Markus J Kemper, Kai Rönnholm, Simone Wygoda and Franz Schaefer

    Citation: BMC Nephrology 2004 5:14

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  19. Content type: Research article

    Hepatitis C virus (HCV) infection is a significant problem among patients undergoing maintenance hemodialysis (HD). We conducted a prospective multi-center study to evaluate the effect of dialysis machine sepa...

    Authors: Alireza Abdollah Shamshirsaz, Mohammad Kamgar, Mir Reza Bekheirnia, Farzam Ayazi, Seyed Reza Hashemi, Navid Bouzari, Mohammad Reza Habibzadeh, Nima Pourzahedgilani, Varshasb Broumand, Amirhooshang Abdollah Shamshirsaz, Maziyar Moradi, Mehrdad Borghei, Niloofar Nobakht Haghighi and Behrooz Broumand

    Citation: BMC Nephrology 2004 5:13

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  20. Content type: Research article

    The commonest cause of end-stage renal failure (ESRF) in children and young adults is congenital malformation of the kidney and urinary tract. In this retrospective review, we examine whether progression to ES...

    Authors: Guy H Neild, Gill Thomson, Dorothea Nitsch, Robin G Woolfson, John O Connolly and Christopher RJ Woodhouse

    Citation: BMC Nephrology 2004 5:12

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  21. Content type: Research article

    Relatively few U.S.-based studies in chronic kidney disease have focused on Asian/Pacific Islanders. Clinical reports suggest that Asian/Pacific Islanders are more likely to be affected by IgA nephropathy (IgA...

    Authors: Yoshio N Hall, Eloisa F Fuentes, Glenn M Chertow and Jean L Olson

    Citation: BMC Nephrology 2004 5:10

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  22. Content type: Case report

    Dialysis disequilibrium syndrome (DDS) is the clinical phenomenon of acute neurologic symptoms attributed to cerebral edema that occurs during or following intermittent hemodialysis (HD). We describe a case of...

    Authors: Sean M Bagshaw, Adam D Peets, Morad Hameed, Paul JE Boiteau, Kevin B Laupland and Christopher J Doig

    Citation: BMC Nephrology 2004 5:9

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  23. Content type: Research article

    During renal transplantation, the kidney remains without blood flow for a period of time. The following reperfusion of this ischemic kidney causes functional and structural injury. Formation of oxygen-derived ...

    Authors: Mehri Kadkhodaee, Simin Aryamanesh, Mahdieh Faghihi and Maryam Zahmatkesh

    Citation: BMC Nephrology 2004 5:6

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  24. Content type: Case report

    The combination of hyponatremia and renovascular hypertension is called hyponatremic hypertensive syndrome (HHS). Malignant hypertension as a presentation has been reported in adults with HHS but is rare in ch...

    Authors: Mehul P Dixit, John D Hughes, Andreas Theodorou and Naznin M Dixit

    Citation: BMC Nephrology 2004 5:5

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  25. Content type: Research article

    Various animal models of renal failure have been produced and used to investigate mechanisms underlying renal disease and develop therapeutic drugs. Most methods available to produce such models appear to invo...

    Authors: Shingo Nakamura, Masuo Terashima, Natsuko Kikuchi, Minoru Kimura, Tadaaki Maehara, Akira Saito and Masahiro Sato

    Citation: BMC Nephrology 2004 5:4

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  26. Content type: Research article

    Although recovery of renal functions in dialysis dependent patients is estimated to be greater than 1%, there are no indicators that actually suggest such revival of renal function. Residual renal function in ...

    Authors: Mahendra Agraharkar, Vasudevan Nair and Matthew Patlovany

    Citation: BMC Nephrology 2003 4:9

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  27. Content type: Case report

    Renal involvement in patients with chronic hepatitis C virus infection has been suggested to be due to a variety of immunological processes. However, the precise mechanism by which the kidneys are damaged in t...

    Authors: Isao Ohsawa, Yuki Uehara, Sumiko Hashimoto, Morito Endo, Takayuki Fujita and Hiroyuki Ohi

    Citation: BMC Nephrology 2003 4:7

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  28. Content type: Case report

    Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by inflammatory serositis (fever, peritonitis, synovitis and pleuritis). The gene locus responsible for FMF was identified in ...

    Authors: Patrick W Fisher, L Tammy Ho, Robert Goldschmidt, Ronald J Semerdjian and Gregory W Rutecki

    Citation: BMC Nephrology 2003 4:6

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  29. Content type: Research article

    The use and possible effects of factors known to improve outcomes in patients with human immunodeficiency virus associated nephropathy (HIVAN), namely of angiotensin converting enzyme inhibitors (ACE) and anti...

    Authors: Kevin C Abbott, Fernando C Trespalacios, Lawrence Y Agodoa and Tejinder S Ahuja

    Citation: BMC Nephrology 2003 4:5

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  30. Content type: Research article

    Oxidative stress may play a critical role in the vascular disease of end stage renal failure and hemodialysis patients. Studies, analyzing either discrete analytes and antioxidant substances, or the integrated...

    Authors: Niki Malliaraki, Dimitris Mpliamplias, Marilena Kampa, Kostas Perakis, Andrew N Margioris and Elias Castanas

    Citation: BMC Nephrology 2003 4:4

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  31. Content type: Research article

    Atherosclerotic ischemic renal disease is a frequent cause of end-stage renal failure leading to dialysis among the elderly; Its prevalence is inferred from autopsy or retrospective arteriographic studies. Thi...

    Authors: Giorgio Coen, Santo Calabria, Silvia Lai, Eleonora Moscaritolo, Italo Nofroni, Giuseppe Ronga, Michele Rossi, Guido Ventroni, Daniela Sardella, Michele Ferrannini, Alvaro Zaccaria and Rosario Cianci

    Citation: BMC Nephrology 2003 4:2

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