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  1. Content type: Research article

    Patients with chronic kidney disease (CKD) are less likely to receive cardiovascular medications. It is unclear whether differential cardiovascular drug use explains, in part, the excess risk of cardiovascular...

    Authors: Nisha Bansal, Chi-yuan Hsu, Malini Chandra, Carlos Iribarren, Stephen P Fortmann, Mark A Hlatky and Alan S Go

    Citation: BMC Nephrology 2011 12:44

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  2. Content type: Research article

    Despite the substantial progress in the quality of critical care, the incidence and mortality of acute kidney injury (AKI) continues to rise during hospital admissions. We conducted a national, multicenter, pr...

    Authors: Laszlo Medve, Csaba Antek, Balazs Paloczi, Szilvia Kocsi, Bela Gartner, Zsuzsanna Marjanek, Gabor Bencsik, Peter Kanizsai and Tibor Gondos

    Citation: BMC Nephrology 2011 12:43

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  3. Content type: Research article

    Chronic Kidney Disease is a major public health problem worldwide with enormous cost burdens on health care systems in developing countries. We aimed to provide a detailed analysis of the processes and costs o...

    Authors: Priyanga Ranasinghe, Yashasvi S Perera, Mohamed FM Makarim, Aruna Wijesinghe and Kamani Wanigasuriya

    Citation: BMC Nephrology 2011 12:42

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  4. Content type: Research article

    Since little is known about chronic kidney disease (CKD) among people living with HIV/AIDS (PLWHA) in Sub-Saharan Africa, the prevalence and nature of CKD were assessed in Burundi through a multicenter cross-s...

    Authors: Johann Cailhol, Béatrice Nkurunziza, Hassan Izzedine, Emmanuel Nindagiye, Laurence Munyana, Evelyne Baramperanye, Janvière Nzorijana, Désiré Sakubu, Théodore Niyongabo and Olivier Bouchaud

    Citation: BMC Nephrology 2011 12:40

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  5. Content type: Study protocol

    Patients with pre-existing impaired renal function are prone to develop acute contrast media induced nephropathy (CIN). Neutrophil gelatinase-associated lipocalin (NGAL), a new biomarker predictive for acute k...

    Authors: Gernot Schilcher, Werner Ribitsch, Ronald Otto, Rupert H Portugaller, Franz Quehenberger, Martini Truschnig-Wilders, Robert Zweiker, Philipp Stiegler, Marianne Brodmann, Klemens Weinhandl and Joerg H Horina

    Citation: BMC Nephrology 2011 12:39

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  6. Content type: Research article

    To investigate whether high blood pressure accelerates renal function decline in patients with advanced chronic kidney disease (CKD), we studied the association of systolic (SBP) and diastolic blood pressure (...

    Authors: Moniek CM de Goeij, Nora Voormolen, Nynke Halbesma, Dinanda J de Jager, Elisabeth W Boeschoten, Yvo WJ Sijpkens, Friedo W Dekker and Diana C Grootendorst

    Citation: BMC Nephrology 2011 12:38

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  7. Content type: Research article

    There is a relative lack of recent information about late post kidney transplantation anaemia (PTA), especially in the developing countries; data are scarce about the prevalence and risk factors of PTA. Sudan ...

    Authors: Amin SI Banaga, Mohamed EA Yousif and Khalifa Elmusharaf

    Citation: BMC Nephrology 2011 12:37

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  8. Content type: Research article

    To study the prevalence of chronic kidney disease (CKD) and its impact on allopurinol dosing and uric acid control among patients with gout.

    Authors: Mahesh J Fuldeore, Aylin A Riedel, Victoria Zarotsky, Bhavik J Pandya, Omar Dabbous and Eswar Krishnan

    Citation: BMC Nephrology 2011 12:36

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  9. Content type: Research article

    Chronic kidney disease (CKD) and end-stage renal disease (ESRD) represent worldwide health problems with an epidemic extent. Therefore, attention must be given to the optimisation of patient care, as gaps in t...

    Authors: Gunar Stemer and Rosa Lemmens-Gruber

    Citation: BMC Nephrology 2011 12:35

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  10. Content type: Study protocol

    Live kidney transplantation (LKT) is underutilized, particularly among ethnic/racial minorities. The effectiveness of culturally sensitive educational and behavioral interventions to encourage patients' early,...

    Authors: L Ebony Boulware, Felicia Hill-Briggs, Edward S Kraus, J Keith Melancon, Raquel McGuire, Bobbie Bonhage, Mikiko Senga, Patti Ephraim, Kira E Evans, Brenda Falcone, Misty U Troll, Nicole Depasquale and Neil R Powe

    Citation: BMC Nephrology 2011 12:34

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  11. Content type: Case report

    Although renal involvement in advanced haematological malignancies is common, glomerulonephritis associated with lymphoproliferative disorders is rare, and the related pathogenetic mechanisms are still poorly ...

    Authors: Spyridon Arampatzis, Nikolaos Giannakoulas, Vassilios Liakopoulos, Theodoros Eleftheriadis, Panagiota Kourti, Foteini Karasavvidou, Panagiota Matsouka and Ioannis Stefanidis

    Citation: BMC Nephrology 2011 12:33

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  12. Content type: Research article

    Hyperuricemia is prevalent in patients with chronic kidney disease (CKD). We explored the hypothesis that asymptmatic hyperuricemia may be associated with new-onset CKD.

    Authors: Masatoshi Kawashima, Koji Wada, Hiroshi Ohta, Hiroyuki Terawaki and Yoshiharu Aizawa

    Citation: BMC Nephrology 2011 12:31

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  13. Content type: Research article

    Animal and human studies suggest that inflammation and malnutrition are common in acute kidney injury (AKI) patients. However, only a few studies reported CRP, a marker of inflammation, albumin, prealbumin and...

    Authors: Qionghong Xie, Ying Zhou, Zhongye Xu, Yanjiao Yang, Dingwei Kuang, Huaizhou You, Shuai Ma, Chuanming Hao, Yong Gu, Shanyan Lin and Feng Ding

    Citation: BMC Nephrology 2011 12:30

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  14. Content type: Research article

    Coping with the stresses of chronic disease is considered as a key factor in the perceived impairment of health related quality of life (HRQL). Little is known though about these associations in chronic kidney...

    Authors: Anna Kaltsouda, Petros Skapinakis, Dimitrios Damigos, Margarita Ikonomou, Rigas Kalaitzidis, Venetsanos Mavreas and Kostas C Siamopoulos

    Citation: BMC Nephrology 2011 12:28

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  15. Content type: Research article

    Renal kallikrein (KLK1) synthesis and urinary excretion are reportedly diminished during AKI (acute kidney injury) in animal models, and provision of kallikrein abrogates renal injury in this setting, but data...

    Authors: Sun Woo Kang, Pei-an Betty Shih, Roy O Mathew, Manjula Mahata, Nilima Biswas, Fangwen Rao, Liying Yan, Josee Bouchard, Rakesh Malhotra, Ashita Tolwani, Srikrishna Khandrika, Ravindra L Mehta and Daniel T O'Connor

    Citation: BMC Nephrology 2011 12:27

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  16. Content type: Case report

    Pulmonary-renal syndrome associated with anti-glomerular basement membrane (GBM) antibodies, also known as Goodpasture's syndrome, is a rare but acute and life-threatening condition. One third of patients pres...

    Authors: Christoph Etter, Ariana Gaspert, Stephan Regenass, Rudolf P Wüthrich, Thomas Kistler, Renate Kain and Clemens D Cohen

    Citation: BMC Nephrology 2011 12:26

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  17. Content type: Research article

    Primary hyperoxaluria type I (PH1) is a rare genetic disorder characterized by allelic and clinical heterogeneity. Four mutations (G170R, 33_34insC, I244T and F152I) account for more than 50% of PH1 alleles an...

    Authors: Ibtihel Benhaj Mbarek, Saoussen Abroug, Asma Omezzine, Dorsaf Zellama, Abdellatif Achour, Abdelaziz Harbi and Ali Bouslama

    Citation: BMC Nephrology 2011 12:25

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  18. Content type: Research article

    Circulating 25-hydroxyvitamin D [25(OH)D] concentration is inversely associated with peripheral arterial disease and hypertension. Vascular remodeling may play a role in this association, however, data relatin...

    Authors: Haimanot Wasse, Francesca Cardarelli, Christine De Staercke, Craig Hooper, Emir Veledar and Idris Guessous

    Citation: BMC Nephrology 2011 12:24

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  19. Content type: Research article

    Increased plasma levels of cellular adhesion molecules (CAMs) have been shown to be predictors of all cause mortality in individuals with chronic renal failure [1, 2] and patients with end-stage renal disease rec...

    Authors: Grainne M Connolly, Ronan Cunningham, Peter T McNamee, Ian S Young and Alexander P Maxwell

    Citation: BMC Nephrology 2011 12:23

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  20. Content type: Research article

    A key goal of anemia management in dialysis patients is to maintain patients' hemoglobin (Hb) levels consistently within a target range. Our aim in this study was to assess the association of facility-level pr...

    Authors: Irfan Khan, Mahesh Krishnan, Anupam Kothawala and Akhtar Ashfaq

    Citation: BMC Nephrology 2011 12:22

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  21. Content type: Research article

    Human leukocyte antigen (HLA) alleles are associated with many autoimmune diseases, including anti-glomerular basement membrane (GBM) disease. In our previous study, it was demonstrated that HLA-DRB1*1501 was ...

    Authors: Huan Luo, Min Chen, Zhao Cui, Rui Yang, Peng-Cheng Xu, Xu-Jie Zhou and Ming-Hui Zhao

    Citation: BMC Nephrology 2011 12:21

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  22. Content type: Debate

    Aluminium-containing phosphate binders have long been used for treatment of hyperphosphatemia in dialysis patients. Their safety became controversial in the early 1980's after reports of aluminium related neur...

    Authors: David W Mudge, David W Johnson, Carmel M Hawley, Scott B Campbell, Nicole M Isbel, Carolyn L van Eps and James JB Petrie

    Citation: BMC Nephrology 2011 12:20

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  23. Content type: Research article

    Macrocytosis occurs in chronic hemodialysis (CHD) patients; however, its significance is unknown. The purpose of this study was to establish the prevalence and distribution of macrocytosis, to identify its cli...

    Authors: Karthik K Tennankore, Steven D Soroka, Kenneth A West and Bryce A Kiberd

    Citation: BMC Nephrology 2011 12:19

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  24. Content type: Research article

    Subclinical inflammation is a common phenomenon in patients on either continuous ambulatory peritoneal dialysis (CAPD) or maintenance hemodialysis (MHD). We hypothesized that vitamin C had anti-inflammation ef...

    Authors: Kunying Zhang, Li Liu, Xuyang Cheng, Jie Dong, Qiuming Geng and Li Zuo

    Citation: BMC Nephrology 2011 12:18

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  25. Content type: Research article

    Previous studies of predictors of end-stage renal disease (ESRD) have limitations: (1) some focused on patients with clinically recognized chronic kidney disease (CKD); (2) others identified population-based p...

    Authors: Eric S Johnson, David H Smith, Micah L Thorp, Xiuhai Yang and Juhaeri Juhaeri

    Citation: BMC Nephrology 2011 12:17

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  26. Content type: Research article

    Extracorporeal lung assist devices are increasingly used in the intensive care unit setting to improve extracorporeal gas exchange mainly in patients with acute respiratory distress syndrome. ARDS is frequentl...

    Authors: Jan T Kielstein, Soeren Tolk, Carsten Hafer, Anna Heiden, Olaf Wiesner, Christian Kühn, Johannes Hadem, Marius M Hoeper and Stefan Fischer

    Citation: BMC Nephrology 2011 12:15

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  27. Content type: Research article

    A rapid decrease of serum potassium concentrations during haemodialysis produces a significant increase in blood pressure parameters at the end of the session, even if effects on intra-dialysis pressure are no...

    Authors: Luca Gabutti, Igor Salvadé, Barbara Lucchini, Davide Soldini and Michel Burnier

    Citation: BMC Nephrology 2011 12:14

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  28. Content type: Research article

    Anemia is common among peritoneal dialysis (PD) patients, and most patients require erythropoiesis-stimulating agents (ESA) to maintain their hemoglobin concentrations within current guideline recommendations....

    Authors: Mariano Feriani, Johan MJ De Meester, Lawrence P McMahon, Jacques B Rottembourg, Ian Bridges, Mourad Farouk and Wolfgang Pronai

    Citation: BMC Nephrology 2011 12:13

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  29. Content type: Research article

    Chronic kidney disease (CKD) is a common disorder associated with increased morbidity and mortality. Primary care physicians (PCPs) care for the majority of pre-dialysis CKD patients; however, PCPs often do no...

    Authors: Khaled Abdel-Kader, Gary S Fischer, James R Johnston, Chen Gu, Charity G Moore and Mark L Unruh

    Citation: BMC Nephrology 2011 12:12

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  30. Content type: Research article

    The increasing use of erythropoietins with long half-lives and the tendency to lengthen the administration interval to monthly injections call for raising awareness on the pharmacokinetics and risks of new ery...

    Authors: Luca Gabutti, Filippo Nobile, Valentina Forni, Fabio Rigamonti, Nadir Weibel and Michel Burnier

    Citation: BMC Nephrology 2011 12:11

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  31. Content type: Study protocol

    Many nephrology observational studies use renal registries, which have well known limitations. The Canadian Kidney Disease Cohort Study (CKDCS) is a large prospective observational study of patients commencing...

    Authors: Aminu K Bello, Ravi Thadhani, Brenda Hemmelgarn, Scott Klarenbach, John Gill, Christopher Chan, Deborah Zimmerman, Daniel Holmes, George Cembrowski, Dawn Opgenorth, Rafael Sibrian, Mohammad Karkhaneh, Sophanny Tiv, Natasha Wiebe and Marcello Tonelli

    Citation: BMC Nephrology 2011 12:10

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  32. Content type: Research article

    Hyperphosphatemia in patients with chronic kidney disease (CKD) contributes to secondary hyperparathyroidism, soft tissue calcification, and increased mortality risk. This trial was conducted to examine the ef...

    Authors: Wajeh Qunibi, Wolfgang C Winkelmayer, Richard Solomon, Moustafa Moustafa, Paul Kessler, Chiang-Hong Ho, Jonathan Greenberg and Jose A Diaz-Buxo

    Citation: BMC Nephrology 2011 12:9

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  33. Content type: Study protocol

    The lack of adequate randomized clinical trials (RCT) has hindered identification of new therapies that are safe and effective for patients with primary focal segmental glomerulosclerosis (FSGS), especially in...

    Authors: Howard Trachtman, Suzanne Vento, Debbie Gipson, Larysa Wickman, Jennifer Gassman, Melanie Joy, Virginia Savin, Michael Somers, Maury Pinsk and Tom Greene

    Citation: BMC Nephrology 2011 12:8

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  34. Content type: Study protocol

    In patients with Stage 5 Chronic Kidney Disease who require renal replacement therapy a major decision concerns modality choice. However, many patients defer the decision about modality choice or they have an ...

    Authors: Mary Ann Murray, Alison Thomas, Ron Wald, Rosa Marticorena, Sandra Donnelly and Lianne Jeffs

    Citation: BMC Nephrology 2011 12:7

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  35. Content type: Study protocol

    Poor adherence to treatment is common in patients on hemodialysis which may increase risk for poor clinical outcomes and mortality. Self management interventions have been shown to be effective in improving co...

    Authors: Konstadina Griva, Nandakumar Mooppil, Penny Seet, Deby Sarojiuy Pala Krishnan, Hayley James and Stanton P Newman

    Citation: BMC Nephrology 2011 12:4

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  36. Content type: Research article

    Defined as estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73 m2, chronic kidney disease (CKD) is strongly and independently associated with cardiovascular and overall mortality. We hypothesized that...

    Authors: Ruth Dubin, Mary Cushman, Aaron R Folsom, Linda F Fried, Walter Palmas, Carmen A Peralta, Christina Wassel and Michael G Shlipak

    Citation: BMC Nephrology 2011 12:3

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  37. Content type: Research article

    A common variant of the UMOD gene was linked with prevalent chronic kidney disease (CKD) in large, genomics consortia. One community-based study found that urine concentrations of the uromodulin protein foreca...

    Authors: Michael G Shlipak, Yongmei Li, Caroline Fox, Josef Coresh, Carl Grunfeld and Mary Whooley

    Citation: BMC Nephrology 2011 12:2

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  38. Content type: Research article

    Primary care providers' suboptimal recognition of the severity of chronic kidney disease (CKD) may contribute to untimely referrals of patients with CKD to subspecialty care. It is unknown whether U.S. primary...

    Authors: Raquel C Greer, Neil R Powe, Bernard G Jaar, Misty U Troll and L Ebony Boulware

    Citation: BMC Nephrology 2011 12:1

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  39. Content type: Research article

    In Singapore, the prevalence of end-stage renal disease (ESRD) and the number of people on dialysis is increasing. The impact of ESRD on patient quality of life has been recognized as an important outcome meas...

    Authors: Veena D Joshi, Nandakumar Mooppil and Jeremy FY Lim

    Citation: BMC Nephrology 2010 11:36

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  40. Content type: Research article

    Compared to healthy people, patients with chronic kidney disease (CKD) participate less in paid jobs and social activities. The aim of the study was to examine a) the perceived autonomy, self-esteem and labor ...

    Authors: Daphne L Jansen, Diana C Grootendorst, Mieke Rijken, Monique Heijmans, Ad A Kaptein, Elisabeth W Boeschoten and Friedo W Dekker

    Citation: BMC Nephrology 2010 11:35

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  41. Content type: Research article

    The complement system is vital for innate immunity and is implicated in the pathogenesis of inflammatory diseases and the mechanism of host defense. Complement deficiencies occasionally cause life-threatening ...

    Authors: Hiroyuki Inoshita, Isao Ohsawa, Gaku Kusaba, Masaya Ishii, Kisara Onda, Satoshi Horikoshi, Hiroyuki Ohi and Yasuhiko Tomino

    Citation: BMC Nephrology 2010 11:34

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  42. Content type: Research article

    Low molecular weight (LMW) heparins are used for anticoagulation during hemodialysis (HD). Studies in animals have shown that LMW-heparins release lipoprotein lipase (LPL) as efficiently as unfractionated (UF)...

    Authors: Dana Mahmood, Maria Grubbström, Lennart DI Lundberg, Gunilla Olivecrona, Thomas Olivecrona and Bernd G Stegmayr

    Citation: BMC Nephrology 2010 11:33

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  43. Content type: Research article

    Minimization of hemodynamic instability during renal replacement therapy (RRT) in patients with acute kidney injury (AKI) is often challenging. We examined the relative hemodynamic tolerability of sustained lo...

    Authors: Heather E Fieghen, Jan O Friedrich, Karen E Burns, Rosane Nisenbaum, Neill K Adhikari, Michelle A Hladunewich, Stephen E Lapinsky, Robert M Richardson and Ron Wald

    Citation: BMC Nephrology 2010 11:32

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  44. Content type: Research article

    Bone Morphogenetic Protein (BMP)-7 is protective in different animal models of acute and chronic kidney disease. Its role in human kidneys, and in particular hypertensive nephrosclerosis, has thus far not been...

    Authors: Carsten P Bramlage, Björn Tampe, Michael Koziolek, Imad Maatouk, Jelena Bevanda, Peter Bramlage, Katharina Ahrens, Katharina Lange, Holger Schmid, Clemens D Cohen, Matthias Kretzler and Gerhard A Müller

    Citation: BMC Nephrology 2010 11:31

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