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  1. Minimal change disease (MCD) is a common cause of the nephrotic syndrome in adults with limited evidence on its treatment and prognosis. We examined the presenting characteristics, treatments, and outcomes of ...

    Authors: Anthony Fenton, Stuart W. Smith and Peter Hewins
    Citation: BMC Nephrology 2018 19:207
    Content type: Research article Published on:

  2. Conservative care is argued to be a reasonable treatment alternative for dialysis in older patients with advanced chronic kidney disease (CKD). However, comparisons are scarce and generally focus on survival o...

    Authors: Wouter R. Verberne, Janneke Dijkers, Johannes C. Kelder, Anthonius B. M. Geers, Wilbert T. Jellema, Hieronymus H. Vincent, Johannes J. M. van Delden and Willem Jan W. Bos
    Citation: BMC Nephrology 2018 19:205
    Content type: Research article Published on:

    The Research note to this article has been published in BMC Research Notes 2019 12:722

  4. Left ventricular hypertrophy (LVH) is one of the risk factors for cardiovascular (CV) disease and mortality. However, the relationship between socioeconomic status (SES) and LVH in chronic kidney disease remai...

    Authors: Eunjeong Kang, Joongyub Lee, Hyo Jin Kim, Miyeun Han, Soo Wan Kim, Kyu-Beck Lee, Suah Sung, Tae-Hyun Yoo, Wookyung Chung, Curie Ahn and Kook-Hwan Oh
    Citation: BMC Nephrology 2018 19:203
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Nephrology 2018 19:217

  5. Volume overload poses a major risk in hemodialysis patients but simple detection methods are lacking. We propose a novel marker, the Interdialytic Creatinine Rise (IDCR), readily calculated as the change in se...

    Authors: Ljubomir M. Ilic, Roger B. Davis, Robert S. Brown and Stewart H. Lecker
    Citation: BMC Nephrology 2018 19:202
    Content type: Research article Published on:

  6. Few post-marketing surveillance studies have examined the safety and efficacy of Rapamune® (Sirolimus) in Asian countries. This study aimed to better understand safety and efficacy of Rapamune for kidney trans...

    Authors: Hee Jung Jeon, Hahn-Ey Lee and Jaeseok Yang
    Citation: BMC Nephrology 2018 19:201
    Content type: Research article Published on:

  7. Microalbuminuria signifies the onset of diabetic nephropathy, but normoalbuminuric patients with diabetes who have a low Glomerular Filtration Rate (GFR) are not uncommon. The purpose of the study was to estim...

    Authors: Polwatta Liyanage Gayani Chandima Liyanage, Sarath Lekamwasam, Thilak Priyantha Weerarathna and Dodanduwa Waduge Shyamal Yashodara Srikantha
    Citation: BMC Nephrology 2018 19:200
    Content type: Research article Published on:

  8. Cardiovascular disease is prevalent in children on dialysis and accounts for almost 30% of all deaths. Randomised trials in adults suggest that haemodiafiltration (HDF) with high convection volumes is associat...

    Authors: Rukshana Shroff, Aysun Bayazit, Constantinos J. Stefanidis, Varvara Askiti, Karolis Azukaitis, Nur Canpolat, Ayse Agbas, Ali Anarat, Bilal Aoun, Sevcan Bakkaloglu, Devina Bhowruth, Dagmara Borzych-DużaÅ‚ka, Ipek Kaplan Bulut, Rainer Büscher, Claire Dempster, Ali Duzova…
    Citation: BMC Nephrology 2018 19:199
    Content type: Study protocol Published on:

  9. Chronic kidney disease (CKD) is often asymptomatic in its early stages but is indicated and is diagnosed with an estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73m2. Certain sociodemographic groups are...

    Authors: Irene Ma, Maggie Guo, Daniel Muruve, Hallgrimur Benediktsson and Christopher Naugler
    Citation: BMC Nephrology 2018 19:198
    Content type: Research article Published on:

  10. Dialysis is often initiated in the hospital during episodes of acute kidney injury and critical illness. Little is known about how patients or their surrogate decision makers feel about dialysis initiation in ...

    Authors: Amar D. Bansal, Nina R. O’Connor and David J. Casarett
    Citation: BMC Nephrology 2018 19:197
    Content type: Research article Published on:

  12. Exercise improves functional outcomes and quality of life of older patients with end-stage renal disease undergoing hemodialysis. Yet exercise is not promoted as part of routine care. Health care providers and...

    Authors: Pia Kontos, Alisa Grigorovich, Romeo Colobong, Karen-Lee Miller, Gihad E. Nesrallah, Malcolm A. Binns, Shabbir M. H. Alibhai, Trisha Parsons, Sarbjit Vanita Jassal, Alison Thomas and Gary Naglie
    Citation: BMC Nephrology 2018 19:195
    Content type: Research article Published on:

  13. While there is a great deal of research updating methods for estimating renal function, many of these methods are being developed in either adults with CKD or younger children. Currently, there is limited unde...

    Authors: Michael Webster-Clark, Byron Jaeger, Yi Zhong, Guido Filler, Ana Alvarez-Elias, Nora Franceschini and Maria E. Díaz-González de Ferris
    Citation: BMC Nephrology 2018 19:194
    Content type: Research article Published on:

  14. Genitourinary tuberculosis (GUTB) is a type of extrapulmonary TB that exerts a deleterious effect on renal function by promoting renal calcification and ureteric stricture. Therefore, we investigated the risk ...

    Authors: Eun Jin Kim, Woonji Lee, Woo Yong Jeong, Hen Choi, In Young Jung, Jin Young Ahn, Su Jin Jeong, Nam Su Ku, Jun Yong Choi, Young Hwa Choi, Young Goo Song and June Myung Kim
    Citation: BMC Nephrology 2018 19:193
    Content type: Research article Published on:

  15. Increased plasma level of lipoprotein(a) (Lpa) is a risk factor of cardiovascular diseases. This study aimed to explore the role of Lpa in the progression of atherosclerosis in patients with end-stage renal di...

    Authors: Kun Ling Ma, Tie Kai Gong, Ze Bo Hu, Yang Zhang, Gui Hua Wang, Liang Liu, Pei Pei Chen, Jian Lu, Chen Chen Lu and Bi Cheng Liu
    Citation: BMC Nephrology 2018 19:192
    Content type: Research article Published on:

  16. Soluble urokinase-type plasminogen activator receptor (suPAR) has emerged as a new sepsis biomarker. It is not known whether suPAR has a role in critically ill patients with severe acute kidney injury (AKI).

    Authors: Anna Hall, Siobhan Crichton, Matt Varrier, Danielle E. Bear and Marlies Ostermann
    Citation: BMC Nephrology 2018 19:191
    Content type: Research article Published on:

  17. Investigations on the role of the time-mean serum uric acid (SUA) value in determining the risk of chronic kidney disease (CKD) are limited. We investigated whether the time-mean SUA value indicates the risk o...

    Authors: Meiyu Ye, Kang Hu, Juan Jin, Diandian Wu, Peiying Hu and Qiang He
    Citation: BMC Nephrology 2018 19:190
    Content type: Research article Published on:

  18. Kidney transplantation (KTx) is the best therapeutic approach for chronic kidney diseases leading to irreversible kidney failure. Considering the origin of the graft, several studies have reported differences ...

    Authors: S. Inés Lozano-Ramos, Ioana Bancu, Laura Carreras-Planella, Marta Monguió-Tortajada, Laura Cañas, Javier Juega, Josep Bonet, M. Pilar Armengol, Ricardo Lauzurica and Francesc E. Borràs
    Citation: BMC Nephrology 2018 19:189
    Content type: Research article Published on:

  19. Ongoing efforts are focused on shortening ischemia intervals as much as possible during partial nephrectomy to preserve renal function. Off-clamp partial nephrectomy (off-PN) has been a common strategy for to ...

    Authors: Wen Deng, Xiaoqiang Liu, Jieping Hu, Luyao Chen and Bin Fu
    Citation: BMC Nephrology 2018 19:188
    Content type: Research article Published on:

  20. Neutrophil to lymphocyte ratio (NLR) was introduced to predict poor prognosis in various diseases, but not all variants of ANCA-associated vasculitis (AAV). In this study, we aimed to investigate whether NLR a...

    Authors: Sung Soo Ahn, Seung Min Jung, Jason Jungsik Song, Yong-Beom Park and Sang-Won Lee
    Citation: BMC Nephrology 2018 19:187
    Content type: Research article Published on:

  21. Both dialysis facilities and hospitals are accountable for 30-day hospital readmissions among U.S. hemodialysis patients. We examined the association of post-hospitalization processes of care at hemodialysis f...

    Authors: Laura C. Plantinga, Tahsin Masud, Janice P. Lea, John M. Burkart, Christopher M. O’Donnell and Bernard G. Jaar
    Citation: BMC Nephrology 2018 19:186
    Content type: Research article Published on:

  22. End stage renal disease (ESRD) is on the rise globally. Varicella infection among adult patients with ESRD has been reported to lead to multiple complications and even death. While varicella vaccination has be...

    Authors: Chong Yau Ong, Sher Guan Low, Farhad Fakhrudin Vasanwala, Shashidhar Baikunje and Lian Leng Low
    Citation: BMC Nephrology 2018 19:185
    Content type: Research article Published on:

  24. Knowing how chronic kidney disease (CKD) patients talk about their encounters with providers (i.e., their discourse) can inform the important clinical goal of engaging patients in their chronic disease self-ma...

    Authors: Ann E. Vandenberg, Katharina V. Echt, Theodore M. Johnson II and C. Barrett Bowling
    Citation: BMC Nephrology 2018 19:183
    Content type: Research article Published on:

  25. Idiopathic membranous nephropathy (IMN) is one of the most common adult nephrotic syndromes. Some patients with this disorder require immunosuppressive therapy. This retrospective case series was performed to ...

    Authors: Shun-Lai Shang, Guang-Yan Cai, Shu-wei Duan, Ping Li, Qing-Gang Li and Xiang-Mei Chen
    Citation: BMC Nephrology 2018 19:182
    Content type: Research article Published on:

  26. Sixty mutations of claudin 16 coding gene have been reported in familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) patients. Recent investigations revealed that a highly conserved glycine...

    Authors: Jingru Lu, Xiangzhong Zhao, Alessandro Paiardini, Yanhua Lang, Irene Bottillo and Leping Shao
    Citation: BMC Nephrology 2018 19:181
    Content type: Case report Published on:

  27. Increasing evidence suggests heat stress induced chronic kidney disease (CKD) may be mediated by endogenous fructose generation and may be exacerbated by rehydration by fructose-containing solutions. We have r...

    Authors: Tamara Milagres, Fernando E. García-Arroyo, Miguel A. Lanaspa, Gabriela Garcia, Takuji Ishimoto, Ana Andres-Hernando, Masanari Kuwabara, Thomas Jensen, Yuka Sato, Jason Glaser, Laura G. Sánchez-Lozada, Richard J. Johnson and Carlos Roncal-Jimenez
    Citation: BMC Nephrology 2018 19:180
    Content type: Research article Published on:

  28. Angiotensin II (Ang II) contributes to the progression of renal diseases associated with proteinuria and glomerulosclerosis mainly by inducing podocyte apoptosis. In the present study, we investigated whether ...

    Authors: Vanessa Gerolde Cardoso, Guilherme Lopes Gonçalves, Juliana Martins Costa-Pessoa, Karina Thieme, Bruna Bezerra Lins, Fernando Augusto Malavazzi Casare, Mariana Charleaux de Ponte, Niels Olsen Saraiva Camara and Maria Oliveira-Souza
    Citation: BMC Nephrology 2018 19:179
    Content type: Research article Published on:

  29. Renal impairment (RI) is common in multiple myeloma (MM) and is associated with poor survival. This study reports the associations between renal function and disease characteristics including serum free light ...

    Authors: Punit Yadav, Paul Cockwell, Mark Cook, Jennifer Pinney, Hannah Giles, Yu Sandar Aung, David Cairns, Roger G. Owen, Faith E. Davies, Graham H. Jackson, J. Anthony Child, Gareth J. Morgan and Mark T. Drayson
    Citation: BMC Nephrology 2018 19:178
    Content type: Research article Published on:

  30. Graft survival after kidney transplantation has significantly improved within the last decades but there is a substantial number of patients with declining transplant function and graft loss. Over the past yea...

    Authors: Anna Wiegand, Alexander Ritter, Nicole Graf, Spyridon Arampatzis, Daniel Sidler, Karine Hadaya, Thomas F. Müller, Carsten A. Wagner, Rudolf P. Wüthrich and Nilufar Mohebbi
    Citation: BMC Nephrology 2018 19:177
    Content type: Study protocol Published on:

  31. Echocardiographic characteristics across the spectrum of chronic kidney disease (CKD) have not been well described. We assessed the echocardiographic characteristics of patients with preserved renal function a...

    Authors: Thomas A. Mavrakanas, Aisha Khattak, Karandeep Singh and David M. Charytan
    Citation: BMC Nephrology 2018 19:176
    Content type: Research article Published on:

  32. The management of proliferative lupus nephritis (LN) comprises timely and coordinated immunosuppressive therapy. This study aimed to evaluate and compare the effectiveness and safety profile of low dose mycoph...

    Authors: Arun Sedhain, Rajani Hada, Rajendra K. Agrawal, Gandhi R. Bhattarai and Anil Baral
    Citation: BMC Nephrology 2018 19:175
    Content type: Research article Published on:

  33. Current guidelines regarding plasma-sampling techniques for glomerular filtration rate (GFR) determination are inconsistent. Single-sample methods are commonly believed not to be precise enough to meet clinica...

    Authors: Yong Zhang, Zhun Sui, Ze Yu, Tai Feng Li, Wan Yu Feng and Li Zuo
    Citation: BMC Nephrology 2018 19:174
    Content type: Research article Published on:

  34. We present a case series of 5 patients with proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) of renal allografts to better define its natural history, presenting characteristics, patholog...

    Authors: Jiqiu Wen, Wei Wang, Feng Xu, Jinsong Chen, Mingchao Zhang, Dongrui Cheng, Xuefeng Ni, Xue Li and Zhihong Liu
    Citation: BMC Nephrology 2018 19:173
    Content type: Research article Published on:

  35. Nephrolithiasis is a risk factor for Osteopenia and osteoporosis. Receptor activator of nuclear factor kappaB ligand (RANKL) and osteoprotegerin (OPG) regulate bone remodeling and osteoclastogenesis. This stud...

    Authors: Asieh Mansour, Maryam Aboeerad, Mostafa Qorbani, Amir Pejman Hashemi Taheri, Mohamad Pajouhi, Abbas Ali Keshtkar, Bagher Larijani, Mohammad Reza Mohajeri-Tehrani and Mohammad Reza Ganji
    Citation: BMC Nephrology 2018 19:172
    Content type: Research article Published on:

  36. Choice of dialysis is context sensitive, explored for PD and extracorporeal dialysis, but less studied for haemodialysis (HD) and hemodiafiltration (HDF), both widely employed in Italy and France; reasons of c...

    Authors: Giorgina Barbara Piccoli, Gianfranca Cabiddu, Maria Rita Moio, Antioco Fois, Riccardo Cao, Ida Molfino, Ana Kaniassi, Francoise Lippi, Ludivine Froger, Antonello Pani and Marilisa Biolcati
    Citation: BMC Nephrology 2018 19:171
    Content type: Research article Published on:

  37. Recurrence of glomerulonephritis is an important risk factor for renal graft dysfunction. Cryoglobulinemia is known as a relatively rare cause of renal failure, and doctors are usually hesitant to perform tran...

    Authors: Tomomichi Kasagi, Hironobu Nobata, Kaori Ikeda, Shogo Banno and Yasuhiko Ito
    Citation: BMC Nephrology 2018 19:170
    Content type: Case report Published on:

  38. Chronic kidney disease (CKD) poses a substantial health burden in sub-Saharan Africa, with risk factors ranging from communicable to non-communicable diseases. Hyperuricemia has been recently identified as a f...

    Authors: Marie Doualla, Marie Patrice Halle, Jude Moutchia, Steve Tegang and Gloria Ashuntantang
    Citation: BMC Nephrology 2018 19:169
    Content type: Research article Published on:

  40. Substrate reduction therapy with analogs reduces the accumulation of substrates by inhibiting the metabolic pathways involved in their biosynthesis, providing new treatment options for patients with primary hy...

    Authors: Huan Yang, Musa Male, Yang Li, Ning Wang, Chenming Zhao, Shan Jin, Juncheng Hu, Zhiqiang Chen, Zhangqun Ye and Hua Xu
    Citation: BMC Nephrology 2018 19:167
    Content type: Research article Published on:

  41. There are conflicting reports on the impact of HIV in the era of combined antiretroviral (c-ART) on survival of patient with ESKD. We aimed to compare the one-year survival of HIV positive patients to that of ...

    Authors: Marie Patrice Halle, Anais Mfoula Edjomo, Hermine Fouda, Hilaire Djantio, Noel Essomba and Gloria Enow Ashuntantang
    Citation: BMC Nephrology 2018 19:166
    Content type: Research article Published on:

  42. Gallbladder perforation is a rare but lethal condition and its diagnosis is usually difficult and delayed. Frequently, gallbladder rupture is associated with cholecystitis, but spontaneous perforation was ever...

    Authors: Yueh-Lin Wu, Yi-Sheng Lin, Thomas Yu-Ren Hsueh, Wen-Ching Lo, Kuo-Chou Peng and Mu-Jung Kao
    Citation: BMC Nephrology 2018 19:165
    Content type: Case report Published on:

  43. Organ donation after brain death (DBD) is the standard strategy for organ transplantation; however, the concept of brain death is not universally accepted due to cultural beliefs and barriers amongst billions ...

    Authors: Qipeng Sun, Honglan Zhou, Ronghua Cao, Minzhuan Lin, Xuefeng Hua, Liangqing Hong, Zhengyu Huang, Ning Na, Ruiming Cai, Gang Wang, Fanhang Meng and Qiquan Sun
    Citation: BMC Nephrology 2018 19:164
    Content type: Research article Published on:

  44. Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disorder, leading to end stage renal failure and kidney transplantation in its most serious form. The severity of the di...

    Authors: Veronika Elisakova, Miroslav Merta, Jana Reiterova, Alica Baxova, Jaroslav Kotlas, Katerina Hirschfeldova, Lena Obeidova, Vladimir Tesar and Jitka Stekrova
    Citation: BMC Nephrology 2018 19:163
    Content type: Case report Published on:

  45. While the majority of adult-onset minimal change nephrotic syndrome (MCNS) is a primary or an idiopathic form of disease, it can also occur as a secondary form. Reports on the spontaneous remission of MCNS are...

    Authors: Ayumi Haruki, Eiji Ishikawa, Kan Katayama, Takayasu Ito, Takuya Hiramoto, Mika Fujimoto, Tomohiro Murata and Masaaki Ito
    Citation: BMC Nephrology 2018 19:162
    Content type: Case report Published on:

  46. Acute kidney injury (AKI) following cardiac surgery is a frequent complication and several risk factors increasing its incidence have already been characterized. This study evaluates the influence of preoperat...

    Authors: T. Kaufeld, K. A. Foerster, T. Schilling, J. T. Kielstein, J. Kaufeld, M. Shrestha, H. G. Haller, A. Haverich and B. M. W. Schmidt
    Citation: BMC Nephrology 2018 19:161
    Content type: Research article Published on:

  47. Hypokalemia is one of the most common clinical electrolyte imbalance problems, and thyrotoxic periodic paralysis (TPP) is a leading cause of presentation to the emergency department. Low renal potassium secret...

    Authors: Mei-Lan Tu, Yu-Wei Fang, Jyh-Gang Leu and Ming-Hsien Tsai
    Citation: BMC Nephrology 2018 19:160
    Content type: Case report Published on:

  48. According to the literature the three stone diseases, sialolithiasis (SL), urolithiasis (UL) and cholelithiasis (CL) share comorbidities. We assess familial and spouse risks between these stone disease and com...

    Authors: Kari Hemminki, Otto Hemminki, Anni I. M. Koskinen, Asta Försti, Kristina Sundquist, Jan Sundquist and Xinjun Li
    Citation: BMC Nephrology 2018 19:158
    Content type: Research article Published on:

  49. Currently, the vasopressin V2 receptor antagonist tolvaptan is the only available treatment for autosomal dominant polycystic kidney disease (ADPKD), but there are tolerability issues due to aquaretic side-eff...

    Authors: Bart J. Kramers, Maatje D. A. van Gastel, Esther Meijer and Ron T. Gansevoort
    Citation: BMC Nephrology 2018 19:157
    Content type: Case report Published on:
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