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  1. Even with abundant evidence for osmotic demyelination in patients with hyponatremia, the risk factors for overcorrection have not been fully investigated. Therefore the purpose of this study is to clarify the ...

    Authors: Sae Aratani, Masahiko Hara, Masahiko Nagahama, Fumika Taki, Miyuki Futatsuyama, Shuichi Tsuruoka and Yasuhiro Komatsu
    Citation: BMC Nephrology 2017 18:316
  2. Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving chronic dialysis therapy. Although cinacalcet can control parathyroid function and bone turnover, preventing ectopic calcific...

    Authors: Daisuke Takada, Tatsuo Tsukamoto, Miho Fuse, Shinpei Kada and Motoko Yanagita
    Citation: BMC Nephrology 2017 18:315
  3. Thymosin β4 (Tβ4) is closely associated with the cytoskeleton, inflammation, wound healing, angiogenesis, apoptosis, and myocardial regeneration, but the effects of Tβ4 treatment on chronic renal tubular inter...

    Authors: Jing Yuan, Yan Shen, Xia Yang, Ying Xie, Xin Lin, Wen Zeng, Yingting Zhao, Maolu Tian and Yan Zha
    Citation: BMC Nephrology 2017 18:314
  4. Complications of peritoneal dialysis (PD) such as pain and catheter leakage are frequently reported. Delayed bowel perforation of a PD catheter is a rare adverse event but a serious complication associated wit...

    Authors: Maki Fujiwara, Takeshi Soda, Takuya Okada, Hiroshi Kanamaru, Takahiro Inoue and Osamu Ogawa
    Citation: BMC Nephrology 2017 18:312
  5. This study aimed to compare clinical features and health-related quality of life (HRQoL) in the Chinese chronic kidney disease (CKD) 3 population and determined the necessity of the subdivision of CKD3 in Chin...

    Authors: Zhangzhe Peng, Jinwei Wang, Qiongjing Yuan, Xiangcheng Xiao, Hui Xu, Yanyun Xie, Wei Wang, Ling Huang, Yong Zhong, Xiang Ao, Luxia Zhang, Minghui Zhao, Lijian Tao and Qiaoling Zhou
    Citation: BMC Nephrology 2017 18:311
  6. Indigenous Australians suffer a disproportionate burden of end stage kidney disease (ESKD) but are significantly less likely to receive a transplant. This study explores Indigenous ESKD patients’ views on tran...

    Authors: Jeannie Devitt, Kate Anderson, Joan Cunningham, Cilla Preece, Paul Snelling and Alan Cass
    Citation: BMC Nephrology 2017 18:310
  7. Arrhythmia-related complications and sudden death are common in dialysis patients. However, routine cardiac monitoring has so far not been feasible. Miniaturization of implantable cardiac monitors offers a new...

    Authors: Naya El Hage, Bernard G. Jaar, Alan Cheng, Chloe Knight, Elena Blasco-Colmenares, Luis Gimenez, Eliseo Guallar and Tariq Shafi
    Citation: BMC Nephrology 2017 18:309
  8. Authors: Sandra Wagner, Marie Metzger, Martin Flamant, Pascal Houillier, Jean-Philippe Haymann, François Vrtovsnik, Eric Thervet, Jean-Jacques Boffa, Ziad A. Massy, Bénédicte Stengel and Patrick Rossignol
    Citation: BMC Nephrology 2017 18:308

    The original article was published in BMC Nephrology 2017 18:295

  9. Prescribing policy recommendations aimed at moving immunosuppressant prescribing for renal transplant patients from primary to secondary care may result in benefits of increased safety and reduced cost. Howeve...

    Authors: Anke Hagemi, Catrin Plumpton and Dyfrig A. Hughes
    Citation: BMC Nephrology 2017 18:305
  10. Regional anticoagulation with citrate is the recommended first line treatment for patients receiving continuous renal replacement therapy (CRRT). There is wide variability in filter patency which may be due to...

    Authors: Richard Fisher, Katie Lei, Mike J. Mitchell, Gary W. Moore, Helen Dickie, Linda Tovey, Siobhan Crichton and Marlies Ostermann
    Citation: BMC Nephrology 2017 18:304
  11. Primary hyperoxaluria type 1 (PH1) is an autosomal recessive inherited disorder of glyoxylate metabolism in which excessive oxalates are formed by the liver and excreted by the kidneys. Calcium oxalate crystal...

    Authors: Houda Kanoun, Faiçal Jarraya, Bayen Maalej, Amina Lahiani, Hichem Mahfoudh, Fatma Makni, Jamil Hachicha and Faiza Fakhfakh
    Citation: BMC Nephrology 2017 18:303
  12. Chronic kidney disease (CKD) has become a major public health issue worldwide in the past few years. Pruritus is a common, well-recognized complication often seen in patients with chronic renal failure. For as...

    Authors: Inayat Ur Rehman and Tahir Mehmood Khan
    Citation: BMC Nephrology 2017 18:302
  13. Accumulating evidences proved the important roles of circulating IgA1-containing immune complexes (cIgA1) in IgA nephropathy (IgAN). Galactose-deficient IgA1 (Gd-IgA1) and glycan-specific IgG antibody have bee...

    Authors: Yan-feng Zhao, Li Zhu, Li-jun Liu, Su-fang Shi, Ji-cheng Lv and Hong Zhang
    Citation: BMC Nephrology 2017 18:301
  14. Cystinosis is a rare autosomal recessive lysosomal disorder characterized by the accumulation of cystine in lysosomes. Cystinosis is much rarer in Asian than Caucasian populations. There are only 14 patients h...

    Authors: Satomi Higashi, Natsuki Matsunoshita, Masako Otani, Etsuro Tokuhiro, Kandai Nozu and Shuichi Ito
    Citation: BMC Nephrology 2017 18:300
  15. Kidney transplantation (KT) is the treatment option for patients with end stage renal disease (ESRD) to prolong survival and improve quality of life. Although the use of potent immunosuppressive agents increas...

    Authors: Yu Ah Hong, Hyeon Seok Hwang, Hae Joung Sul, Suk Young Kim and Yoon Kyung Chang
    Citation: BMC Nephrology 2017 18:299
  16. Early detection and interventions have enabled patients with sickle cell disease (SCD) to live well into adulthood. Consequently, the chronicity of SCD allows for the insidious manifestation of multisystem com...

    Authors: Daveena Meeks, Arunraj Navaratnarajah, Emma Drasar, Ounali Jaffer, C. Jason Wilkins, Swee Lay Thein and Claire C. Sharpe
    Citation: BMC Nephrology 2017 18:298
  17. A balanced diet is essential to slowing the progression of chronic kidney disease (CKD) and managing the symptoms. Currently, no tool is available to easily and quickly assess energy and macronutrient intake i...

    Authors: Aurélie Affret, Sandra Wagner, Douae El Fatouhi, Courtney Dow, Emmanuelle Correia, Maryvonne Niravong, Françoise Clavel-Chapelon, Julie De Chefdebien, Denis Fouque, Bénédicte Stengel, Marie-Christine Boutron-Ruault and Guy Fagherazzi
    Citation: BMC Nephrology 2017 18:297
  18. Low physical activity and reduced physical functioning are common after renal transplantation, resulting in a reduced quality of life. Another common post-transplantation complication is poor cardio-metabolic ...

    Authors: Gerald Klaassen, Dorien M. Zelle, Gerjan J. Navis, Desie Dijkema, Frederike J. Bemelman, Stephan J.L. Bakker and Eva Corpeleijn
    Citation: BMC Nephrology 2017 18:296
  19. Low and high blood potassium levels are common and were both associated with poor outcomes in patients with chronic kidney disease (CKD). Whether such relationships may be altered in CKD patients receiving opt...

    Authors: Sandra Wagner, Marie Metzger, Martin Flamant, Pascal Houillier, Jean-Philippe Haymann, François Vrtovsnik, Eric Thervet, Jean-Jacques Boffa, Ziad A. Massy, Bénédicte Stengel and Patrick Rossignol
    Citation: BMC Nephrology 2017 18:295

    The Correction to this article has been published in BMC Nephrology 2017 18:308

  20. Exercise during haemodialysis improves strength and physical function. However, both patients and clinicians are time poor, and current exercise recommendations add an excessive time burden making exercise a r...

    Authors: Matthew J. Clarkson, Steve F. Fraser, Paul N. Bennett, Lawrence P. McMahon, Catherine Brumby and Stuart A. Warmington
    Citation: BMC Nephrology 2017 18:294
  21. Adults on dialysis are at increased risk of foot ulceration, which commonly precedes more serious lower limb complications, including amputation. Limited data exist regarding the prevalence and factors associa...

    Authors: Michelle R. Kaminski, Anita Raspovic, Lawrence P. McMahon, Katrina A. Lambert, Bircan Erbas, Peter F. Mount, Peter G. Kerr and Karl B. Landorf
    Citation: BMC Nephrology 2017 18:293
  22. The distal convoluted tubule (DCT) is an important nephron site for parathyroid hormone (PTH) and calcitonin regulation of urinary divalent cation excretion. These hormones exert their effects on the DCT in su...

    Authors: Wararat Kittikulsuth, Peter A. Friedman, Alfred van Hoek, Yang Gao and Donald E. Kohan
    Citation: BMC Nephrology 2017 18:292
  23. Cardiovascular (CV) complications are the main cause of death in end-stage renal disease (ESRD) patients. The high CV risks are attributable to the additive effects of multiple factors. Endothelin (EDN) is a p...

    Authors: Chih-Chin Kao, Shih-Ying Cheng, Mei-Yi Wu, Shu-Chen Chien, Hsing-Fang Lu, Yu-Wen Hsu, Yan-Feng Zhang, Mai-Szu Wu and Wei-Chiao Chang
    Citation: BMC Nephrology 2017 18:291
  24. To assess whether serum osteoprotegerin (OPG) and/or fetuin-A predict mortality and cardiovascular (CV) morbidity and mortality in hemodialysis patients.

    Authors: Sílvia Collado, Elisabeth Coll, Carlos Nicolau, Manel Azqueta, Mercedes Pons, Josep M Cruzado, Bernat de la Torre, Ramón Deulofeu, Sergi Mojal, Julio Pascual and Aleix Cases
    Citation: BMC Nephrology 2017 18:290
  25. Acute kidney injury (AKI), which is common among HIV-positive individuals, may contribute to the excess burden of chronic kidney disease (CKD) in this patient population; however, conventional clinical methods...

    Authors: Celia P. Corona-Villalobos, Michael G. Shlipak, Adrienne Tin, Chirag Parikh, Richard D. Moore, Eric Vittinghoff, Jose Manuel Monroy-Trujillo, Mohamed G. Atta and Michelle M. Estrella
    Citation: BMC Nephrology 2017 18:289
  26. Fibronectin glomerulopathy is a rare, inherited, autosomal dominant, glomerular disease characterized by proteinuria, microscopic hematuria, hypertension, massive glomerular deposits of fibronectin, and slow p...

    Authors: Misaki Takii, Takaichi Suehiro, Aya Shima, Hideki Yotsueda, Satoshi Hisano and Ritsuko Katafuchi
    Citation: BMC Nephrology 2017 18:288
  27. Indoleamine 2, 3-dioxygenase (IDO) is an immunomodulatory molecule that has been implicated in several biological processes. Although IDO has been linked with some renal diseases, its role in renal fibrosis is...

    Authors: Luiz Henrique Gomes Matheus, Gislene Mendes Simão, Taíssa Altieri Amaral, Rodrigo Barbosa Oliveira Brito, Camila Soares Malta, Yves Silva Teles Matos, Alexandre Chagas Santana, Gabriela Gomes Cardoso Rodrigues, Maria Clara Albejante, Erna Elisabeth Bach, Maria Aparecida Dalboni, Cleber Pinto Camacho and Humberto Dellê
    Citation: BMC Nephrology 2017 18:287
  28. Isolated pulmonary valve infective endocarditis caused by Candida is rare in chronic hemodialysis patients. The 2009 Infectious Diseases Society of America guidelines suggest the combined use of surgery and antib...

    Authors: Chih-Hao Chang, Myo-Ming Huang, Dong-Feng Yeih, Kuo-Cheng Lu and Yi-Chou Hou
    Citation: BMC Nephrology 2017 18:286
  29. No effective treatment is currently available and dialysis related amyloidosis continues to be invalidating in long-term dialysis patients. A recent case series reported reduction of osteoarticular pain on dox...

    Authors: Giorgina Barbara Piccoli, Mammar Hachemi, Ida Molfino, Jean Philippe Coindre and Charles Boursot
    Citation: BMC Nephrology 2017 18:285
  30. Fracture risk is increased in chronic kidney disease (CKD), but assessment of bone fragility remains controversial in these patients. This study investigated the associations between bone turnover markers, bon...

    Authors: Hanne Skou Jørgensen, Simon Winther, Morten Bøttcher, Ellen-Margrethe Hauge, Lars Rejnmark, My Svensson and Per Ivarsen
    Citation: BMC Nephrology 2017 18:284
  31. Diabetes-related end stage renal disease (DM-ESRD) is a devastating consequence of the type 2 diabetes epidemic, both of which disproportionately affect Indigenous peoples. Projecting case numbers and costs in...

    Authors: Amy Gao, Nathaniel D. Osgood, Ying Jiang and Roland F. Dyck
    Citation: BMC Nephrology 2017 18:283
  32. Arterial stiffness is an independent predictor of all-cause and cardiovascular mortality in patients with chronic kidney disease (CKD). There are limited prospective data however on progression of arterial stiffn...

    Authors: Rathika Krishnasamy, Sven-Jean Tan, Carmel M. Hawley, David W. Johnson, Tony Stanton, Kevin Lee, David W. Mudge, Scott Campbell, Grahame J. Elder, Nigel D. Toussaint and Nicole M. Isbel
    Citation: BMC Nephrology 2017 18:281
  33. The renal vasculature plays important roles in both homeostasis and pathology. In this study, we examined pathological changes in the renal microvascular in mouse models of kidney diseases.

    Authors: Md Abdul Masum, Osamu Ichii, Yaser Hosny Ali Elewa, Teppei Nakamura and Yasuhiro Kon
    Citation: BMC Nephrology 2017 18:280
  34. Despite improved health outcomes associated with arteriovenous fistulas, 80% of Americans initiate hemodialysis using a catheter, influenced by low socioeconomic status among other factors. Risk factors for in...

    Authors: Nicole C. Rich, Shant M. Vartanian, Shimi Sharief, Daniel J. Freitas and Delphine S. Tuot
    Citation: BMC Nephrology 2017 18:279
  35. Glucose is widely used as an osmotic agent in peritoneal dialysis (PD), but exerts untoward effects on the peritoneum. The potential protective effect of a reduced exposure to hypertonic glucose has never been...

    Authors: Dominique Pagniez, Alain Duhamel, Eric Boulanger, Celia Lessore de Sainte Foy and Jean-Baptiste Beuscart
    Citation: BMC Nephrology 2017 18:278
  36. Stroke is the third leading cause of cardiovascular mortality in dialysis patients. The objective of this study was to assess the extent of stroke in chronic hemodialysis patients.

    Authors: Yannick Nlandu, François Lepira, Jean-Robert Makulo, Yannick Engole, Ernest Sumaili, Marie-Noelle Wameso, Vieux Mokoli, Jeannine Luse, Augustin Longo, Chantal Zinga, Pierre Akilimali, Aliocha Nkodila, Mélanie Bavassa, François Kajingulu, Justine Bukabau and Nazaire Nseka
    Citation: BMC Nephrology 2017 18:277
  37. Care coordination is a challenge for patients with kidney disease, who often see multiple providers to manage their associated complex chronic conditions. Much of the focus has been on primary care physician (...

    Authors: Virginia Wang, Clarissa J. Diamantidis, JaNell Wylie and Raquel C. Greer
    Citation: BMC Nephrology 2017 18:274
  38. In the United States, hemodialysis (HD) is generally performed via a bicarbonate dialysate. It is not known if small amounts of acid used in dialysate to buffer the bicarbonate can meaningfully contribute to o...

    Authors: William B. Smith, Sandy Gibson, George E. Newman, Kendra S. Hendon, Margarita Askelson, James Zhao, Jamil Hantash, Brigid Flanagan, John W. Larkin, Len A. Usvyat, Ravi I. Thadhani and Franklin W. Maddux
    Citation: BMC Nephrology 2017 18:273
  39. Secondary hyperparathyroidism (SHPT) is a severe complication for dialysis patients. Vitamin D receptor activators (VDRAs) are used to treat SHPT, but the comparative efficacy and safety between paricalcitol a...

    Authors: Yifeng Xie, Peiling Su, Yifan Sun, Hongsheng Zhang, Rong Zhao, Liang Li and Lanfen Meng
    Citation: BMC Nephrology 2017 18:272
  40. Endophthalmitis is a severe eye infection leading to disabling outcome. Because there were only a few case report illustrating endophthalmitis in chronic dialysis patient, we would like to investigate the epid...

    Authors: George Kuo, Yueh-An Lu, Wei-Chiao Sun, Chao-Yu Chen, Huang-Kai Kao, YuJr Lin, Chia-Hui Lee, Cheng-Chieh Hung, Ya-Chung Tian and Hsiang-Hao Hsu
    Citation: BMC Nephrology 2017 18:270
  41. Periodontal disease occurs relatively prevalently in people with chronic kidney disease (CKD), but it remains indeterminate whether periodontal disease is an independent risk factor for premature death in this...

    Authors: Jian Zhang, Hong Jiang, Min Sun and Jianghua Chen
    Citation: BMC Nephrology 2017 18:269
  42. Tolvaptan slows progression of autosomal dominant polycystic kidney disease (ADPKD) by antagonizing the vasopressin-cAMP axis. Nitric oxide (NO) stimulates natriuresis and diuresis, but its role is unknown dur...

    Authors: Safa Al Therwani, My Emma Sofie Malmberg, Jeppe Bakkestroem Rosenbaek, Jesper Noergaard Bech and Erling Bjerregaard Pedersen
    Citation: BMC Nephrology 2017 18:268

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