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  1. Imatinib is a tyrosine-kinase inhibitor; for which there is limited information regarding its effects on AIDS Kaposi's sarcoma and none in patients with transplant-associated Kaposi's sarcoma. Sirolimus, an im...

    Authors: Patricia Volkow, Juan W Zinser and Ricardo Correa-Rotter

    Citation: BMC Nephrology 2007 8:6

    Content type: Case report

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  2. Thrombocytopenia and absent radius syndrome (TAR) is a rare genetic disorder. It is an autosomal recessive disorder characterised by radial aplasia and thrombocytopenia that may have additional anomalies. We r...

    Authors: Riaz Ahmad

    Citation: BMC Nephrology 2007 8:5

    Content type: Case report

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  3. It is uncertain whether patients with renal vascular disease will have renal or mortality benefit from re-establishing renal blood flow with renal revascularization procedures. The RAVE study will compare rena...

    Authors: Sheldon W Tobe, M Atri, N Perkins, R Pugash and Chaim M Bell

    Citation: BMC Nephrology 2007 8:4

    Content type: Study protocol

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  4. Mercuric chloride (HgCl2) induces an autoimmune nephritis in the Brown Norway (BN) rats characterized by anti-glomerular basement membrane antibodies (anti-GBM Ab) deposition, proteinuria and a severe interstitia...

    Authors: María M Escribese, Elisa Conde, Ana Martín, David Sáenz-Morales, David Sancho, Guillermo Pérez de Lema, Javier Lucio-Cazaña, Francisco Sánchez-Madrid, María L García-Bermejo and Francisco M Mampaso

    Citation: BMC Nephrology 2007 8:3

    Content type: Research article

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  5. The prevalences and risk factors of microalbuminuria are not full described among black African diabetic patients. This study aimed at determining the prevalence of microalbuminuria among African diabetes pati...

    Authors: Janet Joy Kachuchuru Lutale, Hrafnkell Thordarson, Zulfiqarali Gulam Abbas and Kåre Vetvik

    Citation: BMC Nephrology 2007 8:2

    Content type: Research article

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  6. This study used a cross sectional survey to examine the effect of gender, age, and geographical location on the population prevalence of renal replacement therapy (RRT) provision in Wales.

    Authors: Hugo C van Woerden, Jane Wilkinson, Martin Heaven and Jason Merrifield

    Citation: BMC Nephrology 2007 8:1

    Content type: Research article

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  7. Hornet stings are generally associated with local and occasionally anaphylactic reactions. Rarely systemic complications like acute renal failure can occur following multiple stings. Renal failure is usually d...

    Authors: Aman Sharma, Ajay Wanchu, V Mahesha, V Sakhuja, Pradeep Bambery and Surjit Singh

    Citation: BMC Nephrology 2006 7:18

    Content type: Case report

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  8. Small vessel vasculitides are known to follow a devastating course towards end-stage renal disease, unless treated with immunosuppressive regiments. We investigated the value of clinical, histological and immu...

    Authors: Efstathios Alexopoulos, Lazaros Gionanlis, Ekaterini Papayianni, Elizabeth Kokolina, Maria Leontsini and Dimitrios Memmos

    Citation: BMC Nephrology 2006 7:16

    Content type: Research article

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  9. The Renin-Angiotensin system (RAS) is a key regulator of both blood pressure and kidney functions and their interaction. In such a situation, genetic variability in the genes of different components of RAS is ...

    Authors: Gaurav Tripathi, Poonam Dharmani, Faisal Khan, RK Sharma, Vinod Pandirikkal Baburajan and Suraksha Agrawal

    Citation: BMC Nephrology 2006 7:15

    Content type: Research article

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  10. Previous studies have shown that in male rats, exposure to maternal protein restriction either in utero or whilst suckling can have profound effects on both longevity and kidney telomere lengths. This study monit...

    Authors: Clive J Petry, Bridget J Jennings, Lynwen A James, Charles N Hales and Susan E Ozanne

    Citation: BMC Nephrology 2006 7:14

    Content type: Research article

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  11. Due to its strong intra- and inter-individual variability, predicting the ideal erythropoietin dose is a difficult task. The aim of this study was to re-evaluate the impact of the main parameters known to infl...

    Authors: Luca Gabutti, Nathalie Lötscher, Josephine Bianda, Claudio Marone, Giorgio Mombelli and Michel Burnier

    Citation: BMC Nephrology 2006 7:13

    Content type: Research article

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  12. Previous studies have linked smaller kidney dimensions to increased blood pressure. However, patients with Balkan Endemic Nephropathy (BEN), whose kidneys shrink during the course of the disease, do not manife...

    Authors: Plamen S Dimitrov, Valeri A Simeonov, Svetlana D Tsolova, Angel G Bonev, Rossitza B Georgieva and Wilfried J Karmaus

    Citation: BMC Nephrology 2006 7:12

    Content type: Research article

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  13. Medicare beneficiaries without prescription drug coverage consistently fill fewer prescriptions than beneficiaries with some form of drug coverage due to cost. ESRD patients, who are disproportionately poor an...

    Authors: Anisa I Nayeem and Glenn M Chertow

    Citation: BMC Nephrology 2006 7:11

    Content type: Research article

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  14. Advancements in immunosuppressive therapy have significantly improved patient and graft survival following renal transplantation. This is paralleled by an increasing occurrence of posttransplantation malignancy.

    Authors: Roland Schmitt, Ute Kettritz, Friedrich C Luft and Ralph Kettritz

    Citation: BMC Nephrology 2006 7:9

    Content type: Case report

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  15. Many patients with end-stage renal disease use a central venous catheter for hemodialysis access. A large majority of these catheters malfunction within one year of insertion, with up to two-thirds due to thro...

    Authors: Brenda R Hemmelgarn, Louise Moist, Rachel M Pilkey, Charmaine Lok, Marc Dorval, Paul YW Tam, Murray J Berall, Martine LeBlanc, Edwin B Toffelmire, Braden J Manns and Nairne Scott-Douglas

    Citation: BMC Nephrology 2006 7:8

    Content type: Study protocol

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  16. A reduction in the number of podocytes and podocyte density has been documented in the kidneys of patients with diabetes mellitus. Additional studies have shown that podocyte injury and loss occurs in both dia...

    Authors: Brian Siu, Jharna Saha, William E Smoyer, Kelli A Sullivan and Frank C Brosius III

    Citation: BMC Nephrology 2006 7:6

    Content type: Research article

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  17. Chelation therapy with sodium edetate (EDTA) improved renal function and slowed the progression of renal insufficiency in patients subjected to lead intoxication. This study was performed to identify the under...

    Authors: Chiara Foglieni, Alessandro Fulgenzi, Paolo Ticozzi, Fabio Pellegatta, Clara Sciorati, Daniela Belloni, Elisabetta Ferrero and Maria Elena Ferrero

    Citation: BMC Nephrology 2006 7:5

    Content type: Research article

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  18. Chronic kidney disease (CKD) has been linked to higher heart failure (HF) risk. Anemia is a common consequence of CKD, and recent evidence suggests that anemia is a risk factor for HF. The purpose of this stud...

    Authors: Jean-Christophe Luthi, W Dana Flanders, Michel Burnier, Bernard Burnand and William M McClellan

    Citation: BMC Nephrology 2006 7:3

    Content type: Research article

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  19. Nocturnal hemodialysis (NHD) is an alternative to conventional three times per week hemodialysis (CvHD) and has been reported to improve several health outcomes. To date, no randomized controlled trial (RCT) h...

    Authors: Michael Walsh, Braden J Manns, Scott Klarenbach, Robert Quinn, Marcello Tonelli and Bruce F Culleton

    Citation: BMC Nephrology 2006 7:2

    Content type: Study protocol

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  20. Lim1 is a homeobox gene that is essential for nephrogenesis. During metanephric kidney development, Lim1 is expressed in the nephric duct, ureteric buds, and the induced metanephric mesenchyme. Conditional ablat...

    Authors: You-Tzung Chen, Akio Kobayashi, Kin Ming Kwan, Randy L Johnson and Richard R Behringer

    Citation: BMC Nephrology 2006 7:1

    Content type: Research article

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  21. Despite multiple causes, Chronic Kidney Disease is commonly associated with proteinuria. A previous study on Non Obese Diabetic mice (NOD), which spontaneously develop type 1 diabetes, described histological a...

    Authors: Karen HS Wilson, Richard A McIndoe, Sarah Eckenrode, Laurence Morel, Anupam Agarwal, Byron P Croker and Jin-Xiong She

    Citation: BMC Nephrology 2005 6:17

    Content type: Research article

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  22. Crescentic nephritis is characterized by formation of cellular crescents that soon become fibrotic and result in irreversible damage, unless an effective immunosuppressive therapy is rapidly commenced. TGF-β1 is ...

    Authors: Dimitrios S Goumenos, Pantelitsa Kalliakmani, Sotiris Tsakas, Florentia Sotsiou and John G Vlachojannis

    Citation: BMC Nephrology 2005 6:16

    Content type: Research article

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  23. IgA nephropathy (IgAN) or Berger's disease, is the most common glomerulonephritis in the world diagnosed in renal biopsied patients. The involvement of genetic factors in the pathogenesis of the IgAN is eviden...

    Authors: Francesco P Schena, Giuseppina Cerullo, Diletta D Torres, Francesco Scolari, Marina Foramitti, Antonio Amoroso, Doroti Pirulli, Jürgen Floege, Peter R Mertens, Klaus Zerres, Efstathios Alexopoulos, Dimitrios Kirmizis, Leopoldo Zelante, Luigi Bisceglia, Gian M Ghiggeri and Giovanni M Frascà

    Citation: BMC Nephrology 2005 6:14

    Content type: Database

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  24. It has been established that hypothyroidism protects rats against renal ischemia and reperfusion (IR) oxidative damage. However, it is not clear if hypothyroidism is able to prevent protein tyrosine nitration,...

    Authors: Verónica M Tenorio-Velázquez, Diana Barrera, Martha Franco, Edilia Tapia, Rogelio Hernández-Pando, Omar Noel Medina-Campos and José Pedraza-Chaverri

    Citation: BMC Nephrology 2005 6:12

    Content type: Research article

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  25. The National Kidney Foundation has formulated clinical practice guidelines for patients with chronic kidney disease (K/DOQI). However, little is know about how many patients actually achieve these goals in a d...

    Authors: Oliver Lenz, Durga P Mekala, Daniel V Patel, Alessia Fornoni, David Metz and David Roth

    Citation: BMC Nephrology 2005 6:11

    Content type: Research article

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  26. The association between intake of non-phenacetin-containing analgesics and the occurrence of chronic renal failure is still controversially discussed. A new epidemiologic study was planned and conducted in Ger...

    Authors: Lothar AJ Heinemann, Edeltraut Garbe, Michael Lewis, Fokko van der Woude and Helmut Graf

    Citation: BMC Nephrology 2005 6:9

    Content type: Study protocol

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  27. The risk factors for progression of chronic kidney disease (CKD) in type 2 diabetes mellitus (DM) have not been fully elucidated. Although uncontrolled blood pressure (BP) is known to be deleterious, other fac...

    Authors: David J Leehey, Holly J Kramer, Tarek M Daoud, Maninder P Chatha and Majd A Isreb

    Citation: BMC Nephrology 2005 6:8

    Content type: Research article

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  28. Obesity is a growing health issue in the Western world. Obesity, as part of the metabolic syndrome adds to the morbidity and mortality. The incidence of diabetes and hypertension, two primary etiological facto...

    Authors: Sujata Agnani, Vidula T Vachharajani, Rohit Gupta, Naveen K Atray and Tushar J Vachharajani

    Citation: BMC Nephrology 2005 6:7

    Content type: Case report

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  29. In experimental models of diabetes mellitus, aggravation of renal injury by concomitant hypertension has been described. Inflammatory mechanisms contribute to renal damage in both diseases. We investigated whe...

    Authors: Andrea Hartner, Roland Veelken, Michael Wittmann, Nada Cordasic and Karl F Hilgers

    Citation: BMC Nephrology 2005 6:6

    Content type: Research article

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  30. Recombinant human erythropoietin (EPO) is used for the treatment of last stage renal anemia. A new EPO preparation was obtained in Cuba in order to make this treatment fully nationally available. The aim of th...

    Authors: Jorge F Pérez-Oliva, Martha Casanova-González, Idrian García-García, Pedro J Porrero-Martín, Carmen M Valenzuela-Silva, Tairí Hernández-Montero, Marcia Lagarde-Ampudia, Yuri Casanova-Kutsareva, Yisel Ávila-Albuerne, Alicia Vargas-Batista, Hailen Bobillo-López, Raúl Herrera-Valdés and Pedro A López-Saura

    Citation: BMC Nephrology 2005 6:5

    Content type: Research article

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  31. Potassium dichromate (K2Cr2O7)-induced nephrotoxicity is associated with oxidative and nitrosative stress. In this study we investigated the relation between the time course of the oxidative and nitrosative stres...

    Authors: José Pedraza-Chaverrí, Diana Barrera, Omar N Medina-Campos, Raymundo C Carvajal, Rogelio Hernández-Pando, Norma A Macías-Ruvalcaba, Perla D Maldonado, Marcos I Salcedo, Edilia Tapia, Liliana Saldívar, María E Castilla and María E Ibarra-Rubio

    Citation: BMC Nephrology 2005 6:4

    Content type: Research article

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  32. Essential hypertension is a common, polygenic, complex disorder resulting from interaction of several genes with each other and with environmental factors such as obesity, dietary salt intake, and alcohol cons...

    Authors: Adrian Mondry, Marie Loh, Pengbo Liu, Ai-Ling Zhu and Mato Nagel

    Citation: BMC Nephrology 2005 6:1

    Content type: Research article

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  33. The mortality rate among patients with infective endocarditis, especially associated with the presence of complications or coexisting conditions such as renal failure and the use of combined medical and surgic...

    Authors: Daisuke Koya, Kazuyuki Shibuya, Ryuichi Kikkawa and Masakazu Haneda

    Citation: BMC Nephrology 2004 5:18

    Content type: Case report

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  34. Lipoprotein lipase (LPL) has a central role in the catabolism of triglyceride-rich lipoproteins. The enzyme is anchored to the vascular endothelium through interaction with heparan sulphate proteoglycans and i...

    Authors: Birgit Näsström, Bernd Stegmayr, Gunilla Olivecrona and Thomas Olivecrona

    Citation: BMC Nephrology 2004 5:17

    Content type: Research article

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  35. Late referral to specialist nephrological care is associated with increased morbidity, mortality, and cost. Consequently, nephrologists' associations recommend early referral. The recommendations' effectivenes...

    Authors: Adrian Mondry, Ai-Ling Zhu, Marie Loh, Thuy D Vo and Kai Hahn

    Citation: BMC Nephrology 2004 5:16

    Content type: Research article

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  36. Renal artery stenosis (RAS) is a known cause of hypertension and ischemic nephropathy. Stenting of the artery is a valid approach, in spite of cases of unexpected adverse evolution of renal function.

    Authors: Giorgio Coen, Eleonora Moscaritolo, Carlo Catalano, Raffaella Lavini, Italo Nofroni, Giuseppe Ronga, Daniela Sardella, Alvaro Zaccaria and Rosario Cianci

    Citation: BMC Nephrology 2004 5:15

    Content type: Research article

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  37. Peritoneal dialysis (PD) is the preferred dialysis modality in children. Its major drawback is the limited technique survival due to infections and progressive ultrafiltration failure. Conventional PD solution...

    Authors: Barbara Nau, Claus P Schmitt, Margarida Almeida, Klaus Arbeiter, Gianluigi Ardissino, Klaus E Bonzel, Alberto Edefonti, Michel Fischbach, Karin Haluany, Joachim Misselwitz, Markus J Kemper, Kai Rönnholm, Simone Wygoda and Franz Schaefer

    Citation: BMC Nephrology 2004 5:14

    Content type: Study protocol

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  38. Hepatitis C virus (HCV) infection is a significant problem among patients undergoing maintenance hemodialysis (HD). We conducted a prospective multi-center study to evaluate the effect of dialysis machine sepa...

    Authors: Alireza Abdollah Shamshirsaz, Mohammad Kamgar, Mir Reza Bekheirnia, Farzam Ayazi, Seyed Reza Hashemi, Navid Bouzari, Mohammad Reza Habibzadeh, Nima Pourzahedgilani, Varshasb Broumand, Amirhooshang Abdollah Shamshirsaz, Maziyar Moradi, Mehrdad Borghei, Niloofar Nobakht Haghighi and Behrooz Broumand

    Citation: BMC Nephrology 2004 5:13

    Content type: Research article

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  39. The commonest cause of end-stage renal failure (ESRF) in children and young adults is congenital malformation of the kidney and urinary tract. In this retrospective review, we examine whether progression to ES...

    Authors: Guy H Neild, Gill Thomson, Dorothea Nitsch, Robin G Woolfson, John O Connolly and Christopher RJ Woodhouse

    Citation: BMC Nephrology 2004 5:12

    Content type: Research article

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  40. Relatively few U.S.-based studies in chronic kidney disease have focused on Asian/Pacific Islanders. Clinical reports suggest that Asian/Pacific Islanders are more likely to be affected by IgA nephropathy (IgA...

    Authors: Yoshio N Hall, Eloisa F Fuentes, Glenn M Chertow and Jean L Olson

    Citation: BMC Nephrology 2004 5:10

    Content type: Research article

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