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  1. The primary objective of this study is to assess whether baseline renal function impacts treatment outcomes of linezolid and vancomycin (with a dose-optimized regimen) for methicillin-resistant Staphylococcus aur...

    Authors: Ping Liu, Blair Capitano, Amy Stein and Ali A. El-Solh
    Citation: BMC Nephrology 2017 18:168
  2. Circulating pro-inflammatory cytokines were associated with increased relative mortality risk, while immune parameters reflecting improved T-cell function were predictors of survival in hemodialysis (HD) patie...

    Authors: Alicja E. Grzegorzewska, Monika K. Świderska, Adrianna Mostowska, Wojciech Warchoł and Paweł P. Jagodziński
    Citation: BMC Nephrology 2017 18:165
  3. Urinary tract infection is the most common complication after kidney transplantation. It can cause severe sepsis and transplant loss. Emergence of drug resistance among gram-negative urinary pathogens is the c...

    Authors: Johannes Korth, Julia Kukalla, Peter-Michael Rath, Sebastian Dolff, Marco Krull, Hana Guberina, Anja Bienholz, Benjamin Wilde, Stefan Becker, Birgit Ross, Olympia Evdoxia Anastasiou, Andreas Kribben and Oliver Witzke
    Citation: BMC Nephrology 2017 18:164
  4. Whether metformin precipitates lactic acidosis in patients with chronic kidney disease (CKD) remains under debate. We examined whether metformin use was associated with an increased risk of acute kidney injury...

    Authors: Samira Bell, Bassam Farran, Stuart McGurnaghan, Rory J. McCrimmon, Graham P Leese, John R Petrie, Paul McKeigue, Naveed Sattar, Sarah Wild, John McKnight, Robert Lindsay, Helen M. Colhoun and Helen Looker
    Citation: BMC Nephrology 2017 18:163
  5. The ability of antihyperuricemic therapy to exert renoprotective effects in patients with chronic kidney disease (CKD) is controversial. In the present study, we studied patient characteristics that may mask f...

    Authors: Akinori Yamaguchi, Makoto Harada, Yosuke Yamada, Koji Hashimoto and Yuji Kamijo
    Citation: BMC Nephrology 2017 18:162
  6. Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease (CVD), partly due to endothelial dysfunction and chronic inflammation. Vitamin D treatment in end stage renal disease is suggested to...

    Authors: Ladan Mansouri, Kristina Lundwall, Ali Moshfegh, Stefan H. Jacobson, Joachim Lundahl and Jonas Spaak
    Citation: BMC Nephrology 2017 18:161
  7. While chronic kidney disease (CKD) is a growing public health concern in low- and middle-income countries, such as China, few studies have investigated the association between urbanization and the occurrence o...

    Authors: Yosuke Inoue, Annie Green Howard, Amanda L. Thompson, Michelle A. Mendez, Amy H. Herring and Penny Gordon-Larsen
    Citation: BMC Nephrology 2017 18:160
  8. Juvenile idiopathic arthritis (JIA) is a common rheumatic disease in children and adolescents. Although JIA may cause secondary amyloidosis, this is a rare complication in patients with JIA and other rheumatic...

    Authors: Songkiat Chantarogh, Soamarat Vilaiyuk, Thipwimol Tim-Aroon and Suchin Worawichawong
    Citation: BMC Nephrology 2017 18:159
  9. There is a high prevalence of cognitive impairment in dialysis patients. The prevalence of cognitive impairment after kidney transplantation is unknown.

    Authors: Aditi Gupta, Jonathan D. Mahnken, David K. Johnson, Tashra S. Thomas, Dipti Subramaniam, Tyler Polshak, Imran Gani, G. John Chen, Jeffrey M. Burns and Mark J. Sarnak
    Citation: BMC Nephrology 2017 18:158
  10. Fabry Disease (FD) is a genetic disorder caused by alpha-galactosidase A deficiency. Certain drugs, such as hydroxychloroquine, can produce renal deposits that mimic morphological findings seen in FD, characte...

    Authors: Precil Diego Miranda de Menezes Neves, Juliana Reis Machado, Fabiano Bichuette Custódio, Maria Luíza Gonçalves dos Reis Monteiro, Shigueo Iwamoto, Marlene Freire, Marisa França Ferreira and Marlene Antônia dos Reis
    Citation: BMC Nephrology 2017 18:157
  11. There are limited published data on the types and appropriateness of oral and intravenous (IV) antibiotics prescribed to patients receiving haemodialysis. This information is critical to optimise antibiotic pr...

    Authors: Katrina Hui, Michelle Nalder, Kirsty Buising, Aspasia Pefanis, Khai Y Ooi, Eugenie Pedagogos, Craig Nelson, Carl M. J. Kirkpatrick and David C. M. Kong
    Citation: BMC Nephrology 2017 18:156
  12. Chronic Kidney Disease (CKD) is a pressing global health concern that is placing increased strain on health care resources. CKD patients regularly receive peritoneal dialysis as a common CKD treatment. An emer...

    Authors: Lianne Jeffs, Arsh Kumar Jain, Rachel HiuTung Man, Nike Onabajo, Laura Desveaux, James Shaw, Jennifer Hensel, Payal Agarwal, Marianne Saragosa, Trevor Jamieson, Ivy Wong, Maria Maione and R. Sacha Bhatia
    Citation: BMC Nephrology 2017 18:155
  13. A previous cohort study indicated a significant association of lower baseline level of physical activity in hemodialysis patients with elevated risks of mortality. However, there have been no reports regarding...

    Authors: Takahiro Shimoda, Ryota Matsuzawa, Kei Yoneki, Manae Harada, Takaaki Watanabe, Mika Matsumoto, Atsushi Yoshida, Yasuo Takeuchi and Atsuhiko Matsunaga
    Citation: BMC Nephrology 2017 18:154
  14. The pathological condition of chronic kidney disease may not be adequately recapitulated in immunocompromised mice due to the lack of T-cells, which are important for the development of hypertension and renal ...

    Authors: Nynke R. Oosterhuis, Diana A. Papazova, Hendrik Gremmels, Jaap A. Joles and Marianne C. Verhaar
    Citation: BMC Nephrology 2017 18:153
  15. Renal replacement therapy (RRT) is important to support critically ill patients with acute kidney injury (AKI). This study, a part of a nation-wide survey for AKI conducted by the ISN AKF 0 by 25 China Consort...

    Authors: Fang Wang, Daqing Hong, Yafang Wang, Yunlin Feng, Li Wang and Li Yang
    Citation: BMC Nephrology 2017 18:152
  16. The aim was to investigate whether mean perfusion pressure (MPP) calculated as the difference between mean arterial pressure (MAP) and central venous pressure (CVP) was associated with risk of progression from...

    Authors: Marlies Ostermann, Anna Hall and Siobhan Crichton
    Citation: BMC Nephrology 2017 18:151
  17. Many controversies exist regarding the management of dialysis-requiring acute kidney injury (D-AKI). No clear evidence has shown that the choice of dialysis modality can change the survival rate or kidney func...

    Authors: Marisa Aparecida de Souza Oliveira, Thais Oliveira Claizoni dos Santos, Julio Cesar Martins Monte, Marcelo Costa Batista, Virgilio Gonçalves Pereira Jr, Bento Fortunato Cardoso dos Santos, Oscar Fernando Pavão Santos and Marcelino de Souza Durão Jr
    Citation: BMC Nephrology 2017 18:150
  18. Vascular calcification is a major contributing factor to mortality in end stage renal disease (ESRD). Despite the efficacy of phosphate binders to improve hyperphosphatemia, data on vascular calcification are ...

    Authors: A. Neradova, S. P. Schumacher, I. Hubeek, P. Lux, L. J. Schurgers and M. G. Vervloet
    Citation: BMC Nephrology 2017 18:149
  19. Frailty is associated with poor outcomes for patients on dialysis and is traditionally measured using tools that assess physical impairment. Alternate measurement tools highlight cognitive and functional domai...

    Authors: David A. Clark, Usman Khan, Bryce A. Kiberd, Colin C. Turner, Alison Dixon, David Landry, Heather C. Moffatt, Paige A. Moorhouse and Karthik K. Tennankore
    Citation: BMC Nephrology 2017 18:148
  20. Reducing LDL cholesterol (LDL-C) with statin-based therapy reduces the risk of major atherosclerotic events among patients with chronic kidney disease (CKD), with no evidence of an excess risk of cancer or dea...

    Authors: C. Reith, N. Staplin, W. G. Herrington, W. Stevens, J. Emberson, R. Haynes, M. Mafham, J. Armitage, A. Cass, J. C. Craig, L. Jiang, T. Pedersen, C. Baigent and M. J. Landray
    Citation: BMC Nephrology 2017 18:147
  21. Basic and translational research supports beneficial effects of statins on bone metabolism. Clinical studies suggest that statin use may reduce the risk of hip fractures in the general population. Whether stat...

    Authors: Chandan Vangala, Colin R. Lenihan, Maria E. Montez-Rath, Sumi Sukumaran Nair, Sankar D. Navaneethan, Venkat Ramanathan and Wolfgang C. Winkelmayer
    Citation: BMC Nephrology 2017 18:145
  22. Poor physical performance and protein-energy wasting (PEW) are health issues of major concern in haemodialysis patients. The conventional haemodialysis (CHD) regime, three times per week 3–5 h, is subject of d...

    Authors: Manouk Dam, Floor Neelemaat, Trudeke Struijk-Wielinga, Peter J. Weijs and Brigit C. van Jaarsveld
    Citation: BMC Nephrology 2017 18:144
  23. Acute kidney injury (AKI) is being increasingly recognised in ageing populations. There are a paucity of data about AKI risk factors among older individuals with diabetes and infections, who are at particularl...

    Authors: Anu Jain, Helen I. McDonald, Dorothea Nitsch, Laurie Tomlinson and Sara L. Thomas
    Citation: BMC Nephrology 2017 18:142
  24. Missing preadmission serum creatinine (SCr) values are a common obstacle to assess acute kidney injury (AKI) diagnosis and outcomes. The Kidney Disease Improving Global Outcomes (KDIGO) guidelines suggest usin...

    Authors: Amélie Bernier-Jean, William Beaubien-Souligny, Rémi Goupil, François Madore, François Paquette, Stéphan Troyanov and Josée Bouchard
    Citation: BMC Nephrology 2017 18:141
  25. Gitelman syndrome (GS) is a rare autosomal recessively inherited salt-wasting tubulopathy associated with mutations in the SLC12A3 gene, which encodes for NaCl cotransporter (NCC) in the kidney.

    Authors: Chandrika Jayakanthi Subasinghe, Nirmala Dushyanthi Sirisena, Chula Herath, Knut Erik Berge, Trond Paul Leren, Uditha Bulugahapitiya and Vajira Harshadeva Weerabaddana Dissanayake
    Citation: BMC Nephrology 2017 18:140
  26. IgG4-related disease is a recently described pathologic entity. This is the case of a patient with nephrotic syndrome and lymphadenopathy due to IgG4-related disease. Such a kidney involvement is quite peculia...

    Authors: Justine Huart, Stéphanie Grosch, Christophe Bovy, Michel Moutschen and Jean-Marie Krzesinski
    Citation: BMC Nephrology 2017 18:139
  27. Preserved residual kidney function (RKF) and normal fluid status are associated with better patient outcomes in incident haemodialysis patients. The objective of this trial is to determine whether using bioimp...

    Authors: Simon J. Davies, Fergus J. Caskey, David Coyle, Elizabeth Lindley, Jamie Macdonald, Sandip Mitra, Martin Wilkie, Andrew Davenport, Ken Farrington, Indranil Dasgupta, Paula Ormandy, Lazaros Andronis, Ivonne Solis-Trapala and Julius Sim
    Citation: BMC Nephrology 2017 18:138
  28. Calciphylaxis is a serious complication in patients with chronic kidney disease associated mineral and bone disorder. It can occur in conditions with low and high bone turnover. So far, there are no definite d...

    Authors: Margret Patecki, Gabriele Lehmann, Jan Hinrich Bräsen, Jessica Schmitz, Anna Bertram, Lars Daniel Berthold, Hermann Haller and Wilfried Gwinner
    Citation: BMC Nephrology 2017 18:137
  29. Whilst still rare, the incidence of paediatric stone disease is increasing in developed countries and it is important to evaluate the aetiology. We set up a dedicated renal stone service for children combining...

    Authors: Naomi Issler, Stephanie Dufek, Robert Kleta, Detlef Bockenhauer, Naima Smeulders and William van‘t Hoff
    Citation: BMC Nephrology 2017 18:136
  30. Screening for persistent albuminuria among the high-risk population is important for early detection of CKD while studies regarding screening protocol and related cost-effectiveness analysis are limited. This ...

    Authors: Huaiyu Wang, Li Yang, Fang Wang and Luxia Zhang
    Citation: BMC Nephrology 2017 18:135
  31. Patients with an impaired renal function show a high incidence of bone and mineral disturbances. These ‘chronic kidney disease – mineral and bone disorders’ (CKD-MBD) range from high turnover osteoporosis to a...

    Authors: Ruth G. G. Hiller, Margret Patecki, Claudia Neunaber, Janin Reifenrath, Jan T. Kielstein and Heike Kielstein
    Citation: BMC Nephrology 2017 18:134
  32. Simkania negevensis is an obligate intracellular bacterium belonging to the family Simkaniaceae in the Chlamydiales order. It is considered an ubiquitous microorganism and aquatic envi...

    Authors: Andrea Angeletti, Roberta Biondi, Giuseppe Battaglino, Eleonora Cremonini, Giorgia Comai, Irene Capelli, Gabriele Donati, Roberto Cevenini, Manuela Donati and Gaetano La Manna
    Citation: BMC Nephrology 2017 18:133
  33. Whether screening for chronic kidney disease (CKD) can improve the care of persons at high risk for complications remains uncertain. We describe the design and early implementation experience of a pilot, clust...

    Authors: Carmen A. Peralta, Martin Frigaard, Anna D. Rubinsky, Leticia Rolon, Lowell Lo, Santhi Voora, Karen Seal, Delphine Tuot, Shirley Chao, Kimberly Lui, Phillip Chiao, Neil Powe and Michael Shlipak
    Citation: BMC Nephrology 2017 18:132
  34. Patients who start renal replacement therapy (RRT) for End-Stage Kidney Disease (ESKD) without having had timely access to specialist renal services have poor outcomes. At one NHS Trust in England, a community...

    Authors: Hugh Gallagher, Shona Methven, Anna Casula, Nicola Thomas, Charles R. V. Tomson, Fergus J. Caskey, Tracey Rose, Stephen J. Walters, David Kennedy, Anne Dawnay, Martin Cassidy, Richard Fluck, Hugh C. Rayner and Michael Nation
    Citation: BMC Nephrology 2017 18:131
  35. Ischemia and reperfusion (I/R) is one of the major causes of acute kidney injury (AKI). Citrate reduces hypoxia-induced mitochondrial energetic deficits in isolated proximal tubules. Moreover, citrate anticoag...

    Authors: Anja Bienholz, Jonas Reis, Pinar Sanli, Herbert de Groot, Frank Petrat, Hana Guberina, Benjamin Wilde, Oliver Witzke, Fuat H. Saner, Andreas Kribben, Joel M. Weinberg and Thorsten Feldkamp
    Citation: BMC Nephrology 2017 18:130
  36. Coronary artery calcification (CAC) is highly prevalent among dialysis patients and is associated with increased cardiovascular and all cause mortality. Magnesium (Mg) inhibits vascular calcification in animal...

    Authors: Amber O. Molnar, Mohan Biyani, Ian Hammond, John Paul Harmon, Susan Lavoie, Brendan McCormick, Manish M. Sood, Jessica Wagner, Elena Pena and Deborah L. Zimmerman
    Citation: BMC Nephrology 2017 18:129
  37. Dementia is common in end-stage renal disease (ESRD) patients on hemodialysis (HD) and is associated with worse outcomes. This study aimed to investigate the risk of major adverse cardiac and cerebrovascular e...

    Authors: Sung Min Jung, Clara Tammy Kim, Ea Wha Kang, Kyoung Hoon Kim, Shina Lee, Hyung Jung Oh, Seung-Jung Kim, Duk-Hee Kang, Kyu Bok Choi, Dong-Ryeol Ryu and Hyunwook Kim
    Citation: BMC Nephrology 2017 18:128
  38. Proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) is a form of renal involvement by monoclonal IgG deposits that was found in mesangial, subendothelial or subepithelial regions. The distri...

    Authors: Rio Noto, Nozomu Kamiura, Yuichiro Ono, Sumie Tabata, Shigeo Hara, Hideki Yokoi, Akihiro Yoshimoto and Motoko Yanagita
    Citation: BMC Nephrology 2017 18:127
  39. Home telemonitoring has developed considerably over recent years in chronic diseases in order to improve communication between healthcare professionals and patients and to promote early detection of deteriorat...

    Authors: Nathalie Thilly, Jacques Chanliau, Luc Frimat, Christian Combe, Pierre Merville, Philippe Chauveau, Pierre Bataille, Raymond Azar, David Laplaud, Christian Noël and Michèle Kessler
    Citation: BMC Nephrology 2017 18:126
  40. Sleep apnea is common and associated with poor outcome in severe chronic kidney disease, but validated screening tools are not available. Our objectives were to determine the prevalence of sleep apnea in this ...

    Authors: Hsin-Chia Huang, Giles Walters, Girish Talaulikar, Derek Figurski, Annette Carroll, Mark Hurwitz, Krishna Karpe and Richard Singer
    Citation: BMC Nephrology 2017 18:125
  41. Drug induced kidney injury is a frequent adverse event which contributes to morbidity and increased healthcare utilization. Our current knowledge of drug induced kidney disease is limited due to varying defini...

    Authors: Linda Awdishu and Ravindra L. Mehta
    Citation: BMC Nephrology 2017 18:124
  42. Pre-produced bicarbonate concentrates (PPC) are still widely used in developing countries despite its cost and risk but Central Concentrate System (CCS) is lacking in data to support its wider adoption.

    Authors: K. Fauziah, K. W. Go, A. Ghazali, M. Zaki and T. O. Lim
    Citation: BMC Nephrology 2017 18:123
  43. Paraquat ingestion is frequently fatal. While biomarkers of kidney damage increase during paraquat-induced acute kidney injury (AKI), significant concurrent proteinuria may alter diagnostic thresholds for diag...

    Authors: Fahim Mohamed, Nicholas A. Buckley, John W. Pickering, Klintean Wunnapuk, Sandamali Dissanayake, Umesh Chathuranga, Indika Gawarammana, Shaluka Jayamanne and Zoltan H. Endre
    Citation: BMC Nephrology 2017 18:122
  44. Accidental intake of mushrooms of the Cortinarius species (deadly webcap) may cause irreversible renal damage and the need for dialysis or transplantation. The species is found in forests of Northern Europe, Scan...

    Authors: Heidi Hedman, Johan Holmdahl, Johan Mölne, Kerstin Ebefors, Börje Haraldsson and Jenny Nyström
    Citation: BMC Nephrology 2017 18:121
  45. The highly burdensome effects of kidney failure and its management impose many life-altering changes on patients. Better understanding of successful coping strategies will inform patients and help health care ...

    Authors: Lalita Subramanian, Martha Quinn, Junhui Zhao, Laurie Lachance, Jarcy Zee and Francesca Tentori
    Citation: BMC Nephrology 2017 18:119
  46. Iron deficiency anemia (IDA) is a common manifestation of chronic kidney disease (CKD), affecting most patients on hemodialysis and imposing a substantial clinical burden. Treatment with iron supplementation i...

    Authors: Iain C. Macdougall, Naomi V. Dahl, Kristine Bernard, Zhu Li, Alka Batycky and William E. Strauss
    Citation: BMC Nephrology 2017 18:117

    The Correction to this article has been published in BMC Nephrology 2018 19:97

  47. Hypertension and chronic kidney disease (CKD) are common conditions and both are major risk factors for cardiovascular events. The objectives were 1) to study the prevalence of CKD in hypertensive patients and...

    Authors: Rungroj Krittayaphong, Ram Rangsin, Bandit Thinkhamrop, Cameron Hurst, Suthee Rattanamongkolgul, Nintita Sripaiboonkij and Wipaporn Wangworatrakul
    Citation: BMC Nephrology 2017 18:115

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