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  1. Patients with chronic kidney disease (CKD) due to glomerulonephritis (GN) are thought to be at high risk for cardiovascular disease (CVD). However, no study has examined whether GN directly contributes to CV r...

    Authors: Holly L. Hutton, Adeera Levin, Jagbir Gill, Ognjenka Djurdjev, Mila Tang and Sean J. Barbour
    Citation: BMC Nephrology 2017 18:95
    Content type: Research article Published on:

  2. Delta neutrophil index (DNI), representing an elevated fraction of circulating immature granulocytes in acute infection, has been reported as a useful marker for predicting mortality in patients with sepsis. T...

    Authors: In Mi Han, Chang-Yun Yoon, Dong Ho Shin, Youn Kyung Kee, Seung Gyu Han, Young Eun Kwon, Kyoung Sook Park, Mi Jung Lee, Hyung Jung Oh, Jung Tak Park, Seung Hyeok Han, Shin-Wook Kang and Tae-Hyun Yoo
    Citation: BMC Nephrology 2017 18:94
    Content type: Research article Published on:

  3. Acute Kidney Injury (AKI) is a well recognized complication of cardiac surgery. It is associated with significant morbidity and mortality. The aims of our study are twofold;

     

    Authors: Keren Grynberg, Kevan R. Polkinghorne, Sharon Ford, Fiona Stenning, Thomas E. Lew, Jonathan A. Barrett and Shaun A. Summers
    Citation: BMC Nephrology 2017 18:93
    Content type: Research article Published on:

  4. Snakebite-related acute kidney injury (AKI) is a common community-acquired AKI in tropical countries leading to death and disability. The aims of this study were to (1) determine the occurrence of snakebite-re...

    Authors: Kyi-Phyu Aye, Vipa Thanachartwet, Chit Soe, Varunee Desakorn, Khin-Thida Thwin, Supat Chamnanchanunt, Duangjai Sahassananda, Thanom Supaporn and Visith Sitprija
    Citation: BMC Nephrology 2017 18:92
    Content type: Research article Published on:

  5. Metallothionein (MTT) is an endogenous antioxidant that can be induced by both zinc (Zn) and ischemia. In kidneys, increased MTT expression exerts a putative protective role in diabetes and hypoxia. Our goal w...

    Authors: Moritz Schanz, Lea Schaaf, Juergen Dippon, Dagmar Biegger, Peter Fritz, Mark Dominik Alscher and Martin Kimmel
    Citation: BMC Nephrology 2017 18:91
    Content type: Research article Published on:

  6. Stroke and low heart rate variability (HRV) are both associated with an unfavorable prognosis in hemodialysis patients. The relationship between stroke and changes in HRV during hemodialysis remains unclear.

    Authors: Jiun-Chi Huang, Chien-Fu Chen, Chia-Chu Chang, Szu-Chia Chen, Ming-Chia Hsieh, Yao-Peng Hsieh and Hung-Chun Chen
    Citation: BMC Nephrology 2017 18:90
    Content type: Research article Published on:

  7. IgA nephropathy (IgAN) is the most frequent glomerulonephritis in many countries including Estonia. There is no specific treatment for IgAN but renoprotection is indicated when proteinuria is >1 g/day. We aime...

    Authors: Živile Riispere, Anne Kuudeberg, Elviira Seppet, Kristin Sepp, Madis Ilmoja, Merike Luman, Külli Kõlvald, Asta Auerbach and Mai Ots-Rosenberg
    Citation: BMC Nephrology 2017 18:89
    Content type: Research article Published on:

  8. Tuberculosis (TB) is a common opportunistic infection after kidney transplantation (KT). The QuantiFERON-TB-Gold In-Tube test (QFT) is widely used for assessing latent TB; however, it is currently unclear whet...

    Authors: Enkthuya Jambaldorj, Miyeun Han, Jong Cheol Jeong, Tai Yeon Koo, Sang Il Min, Eun Young Song, Jongwon Ha, Curie Ahn and Jaeseok Yang
    Citation: BMC Nephrology 2017 18:88
    Content type: Research article Published on:

  10. Tolvaptan is a selective vasopressin receptor antagonist. Nitric Oxide (NO) promotes renal water and sodium excretion, but the effect is unknown in the nephron’s principal cells. In a dose-response study, we m...

    Authors: Safa Al Therwani, Jeppe Bakkestrøm Rosenbæk, Frank Holden Mose, Jesper Nørgaard Bech and Erling Bjerregaard Pedersen
    Citation: BMC Nephrology 2017 18:86
    Content type: Research article Published on:

  11. Better treatment during early stages of chronic kidney disease (CKD) may slow progression to end-stage renal disease and decrease associated complications and medical costs. Achieving early treatment of CKD is...

    Authors: Benjamin O. Yarnoff, Thomas J. Hoerger, Siobhan K. Simpson, Alyssa Leib, Nilka R. Burrows, Sundar S. Shrestha and Meda E. Pavkov
    Citation: BMC Nephrology 2017 18:85
    Content type: Research article Published on:

  13. In developing countries, renal specialists are scarce and physician-to-patient contact time is limited. While conventional hospital-based, physician-oriented approach has been the main focus of chronic kidney ...

    Authors: Teerayuth Jiamjariyapon, Atiporn Ingsathit, Krit Pongpirul, Kotcharat Vipattawat, Suphattra Kanchanakorn, Akhathai Saetie, Duangjit Kanistanon, Patimaporn Wongprompitak, Vinai Leesmidt, Watcharapong Watcharasaksilp, Wei Wang, Anil K. Chandraker and Kriang Tungsanga
    Citation: BMC Nephrology 2017 18:83
    Content type: Research article Published on:

  14. Coronary artery disease (CAD) is common in asymptomatic chronic dialysis patients and plays an important role in their poor survival. Early identification of these high-risk patients could improve treatment an...

    Authors: M. K. de Bie, M. S. Buiten, J. I. Rotmans, M. Hogenbirk, M. J. Schalij, T. J. Rabelink and J. W. Jukema
    Citation: BMC Nephrology 2017 18:82
    Content type: Research article Published on:

  15. Regional citrate anticoagulation (RCA) is proposed for various extracorporeal purification techniques to overcome the risk of bleeding that might result from systemic anticoagulation. Yet, no individualized tr...

    Authors: Sébastien Kissling, Cécile Legallais, Menno Pruijm, Daniel Teta, Bruno Vogt, Michel Burnier, Eric Rondeau and Christophe Ridel
    Citation: BMC Nephrology 2017 18:81
    Content type: Technical advance Published on:

    The Erratum to this article has been published in BMC Nephrology 2017 18:84

  16. Patients with diabetes and chronic kidney disease (CKD) are a complex subset of the growing number of patients with diabetes, due to multi-morbidity. Gaps between recommended and received care for diabetes and...

    Authors: C. Lo, H. Teede, G. Fulcher, M. Gallagher, P. G. Kerr, S. Ranasinha, G. Russell, R. Walker and S. Zoungas
    Citation: BMC Nephrology 2017 18:80
    Content type: Research article Published on:

  17. Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease (CVD) events, and a number of reports have shown a relationship between CKD and CVD in pre-dialysis or maintenance dialysis...

    Authors: Daijo Inaguma, Shigehisa Koide, Kazuo Takahashi, Hiroki Hayashi, Midori Hasegawa and Yukio Yuzawa
    Citation: BMC Nephrology 2017 18:79
    Content type: Research article Published on:

  18. Acute kidney injury (AKI) is a common complication in the critically ill patients and associated with a substantial morbidity and mortality. Severe AKI may be associated with up to 60% hospital mortality. Over...

    Authors: Girish Chandra Bhatt and Rashmi Ranjan Das
    Citation: BMC Nephrology 2017 18:78
    Content type: Research article Published on:

  19. Hypertension is one of the most important causes of end-stage renal disease, but it is unclear whether elevated blood pressure (BP) also accelerates the gradual decline in the glomerular filtration rate (GFR) ...

    Authors: Bjørn O. Eriksen, Vidar T. N. Stefansson, Trond G. Jenssen, Ulla D. Mathisen, Jørgen Schei, Marit D. Solbu, Tom Wilsgaard and Toralf Melsom
    Citation: BMC Nephrology 2017 18:77
    Content type: Research article Published on:

  20. The early identification of patients with ANCA-associated vasculitis (AAV) who are at increased risk for inferior clinical outcome at the time of diagnosis might help to optimize the immunosuppressive therapy....

    Authors: Ágnes Haris, Kálmán Polner, József Arányi, Henrik Braunitzer, Ilona Kaszás, László Rosivall, Gábor Kökény and István Mucsi
    Citation: BMC Nephrology 2017 18:76
    Content type: Research article Published on:

  21. Voluntary apnea during breath-hold diving (BHD) induces cardiovascular changes including bradycardia, reduced cardiac output, and arterial hypertension. Although the impacts of repetitive BHD on cardiovascular...

    Authors: Yun Jung Oh, Ji Yong Jung, Sung Soo Kim, Kyong-Suk Chae, Jiwon Rhu and Chungsik Lee
    Citation: BMC Nephrology 2017 18:75
    Content type: Research article Published on:

  22. Little is known about vascular access conversion and outcomes for patients starting hemodialysis with nonfunctional arteriovenous (AV) access. We assessed mortality risk associated with nonfunctional AV access...

    Authors: Natalia Alencar de Pinho, Raphael Coscas, Marie Metzger, Michel Labeeuw, Carole Ayav, Christian Jacquelinet, Ziad A Massy and Bénédicte Stengel
    Citation: BMC Nephrology 2017 18:74
    Content type: Research article Published on:

  23. Renal injury is a serious complication after cardiac surgery and therefore, early detection and much more prediction of postoperative kidney injury is desirable. Neutrophil gelatinase-associated lipocalin (NGA...

    Authors: Martin G. Friedrich, Ioannis Bougioukas, Johanna Kolle, Christian Bireta, Fawad A. Jebran, Marius Placzek and Theodor Tirilomis
    Citation: BMC Nephrology 2017 18:73
    Content type: Research article Published on:

  25. Hemodialysis (HD) with ultrafiltration (UF) in chronic renal replacement therapy is associated with hemodynamic instability, morbidity and mortality. Sublingual Sidestream Dark Field (SDF) imaging during HD re...

    Authors: Gerke Veenstra, Andrius Pranskunas, Inga Skarupskiene, Vidas Pilvinis, Marc H. Hemmelder, Can Ince and E. Christiaan Boerma
    Citation: BMC Nephrology 2017 18:71
    Content type: Research article Published on:

  26. Acute kidney injury (AKI) is a serious complication of critical illness with both attributed morbidity and mortality at short-term and long-term. The incidence of AKI reported in critically ill patients varies...

    Authors: J. Koeze, F. Keus, W. Dieperink, I. C. C. van der Horst, J. G. Zijlstra and M. van Meurs
    Citation: BMC Nephrology 2017 18:70
    Content type: Research article Published on:

  27. Optimising filter life and performance efficiency in continuous renal replacement therapy has been a focus of considerable recent research. Larger high quality studies have predominantly focussed on optimal an...

    Authors: Matthew Brain, Elizabeth Winson, Owen Roodenburg and John McNeil
    Citation: BMC Nephrology 2017 18:69
    Content type: Research article Published on:

  28. Serum β-trace protein (βTP, MW 23–29 kDa) is a marker of GFR impairment in renal patients. Recent papers propose to predict residual renal function (RRF) in maintenance haemodialysis (MHD) patients from serum ...

    Authors: Carlo Donadio, Danika Tognotti, Laura Caponi and Aldo Paolicchi
    Citation: BMC Nephrology 2017 18:68
    Content type: Research article Published on:

  29. Injury to the kidney epithelial barrier is a characteristic feature of acute kidney injury (AKI). Serum surfactant protein-D (SP-D), a known biomarker of damaged alveolar epithelium, is also secreted by renal ...

    Authors: Jiao Liu, Guang Li, Lianghai Li, Zhiyong Liu, Qingshan Zhou, Guirong Wang and Dechang Chen
    Citation: BMC Nephrology 2017 18:67
    Content type: Research article Published on:

  30. The clinical effect of bisphosphonate treatment has not been clearly evaluated by kidney function in Japanese Chronic Kidney Disease (CKD) patients with osteoporosis. This study analyzed the data from three ri...

    Authors: Takashi Shigematsu, Ryoichi Muraoka, Toshitsugu Sugimoto and Yoshiki Nishizawa
    Citation: BMC Nephrology 2017 18:66
    Content type: Research article Published on:

  31. Interleukin-19 (IL-19) is a newly discovered cytokine belonging to the Interleukin-10(IL-10) family. IL-19 have indispensable functions in many inflammatory processes and also can induce the angiogenic potenti...

    Authors: Li Li, Xu-gan Jiang, Juan-Yu Hu, ZHeng-Qing Yu, Jian-Yong Xu, Fan Liu, Guang-Chun Zhao, Lei Zhang, Hui-Ming Gu, Si-Jing Zhang and Jin Meng
    Citation: BMC Nephrology 2017 18:65
    Content type: Research article Published on:

  32. Infection with the human T-cell lymphotropic virus type 1 (HTLV-1), although asymptomatic in most cases, can lead to potentially grave consequences, such as adult T-cell leukemia-lymphoma and HTLV-1-associated...

    Authors: Rilma F. S. Santos, Gildásio C. Conceição, Márcia S. Martins, Angiolina Kraychete, Maria A. C. Penalva, Edgar M. Carvalho, Antonio Alberto Lopes and Paulo Novis Rocha
    Citation: BMC Nephrology 2017 18:64
    Content type: Research article Published on:

  33. Immunoglobulin A nephropathy (IgAN) is the most common glomerulonephritis worldwide. The clinical spectrum of IgAN varies from minor urinary abnormalities to rapidly progressive renal failure. Evaluation of th...

    Authors: Shuang Liang, Guang-Yan Cai, Zhi-Yu Duan, Shu-wen Liu, Jie Wu, Yang Lv, Kai Hou, Zuo-xiang Li, Xue-Guang Zhang and Xiang-Mei Chen
    Citation: BMC Nephrology 2017 18:63
    Content type: Research article Published on:

  34. Goblet cell carcinoid is a rare variant of appendiceal carcinoid with mixed endocrine and exocrine features. The most common symptom and signs are abdominal pain, acute appendicitis and palpable mass. Addition...

    Authors: Chih-Wei Chen, Jan-Show Chu, Li-Chun Hsieh, Chih-Chin Kao, Yen-Chung Lin and Hsi-Hsien Chen
    Citation: BMC Nephrology 2017 18:62
    Content type: Case report Published on:

  35. IgA nephropathy is the most common progressive glomerular disease to end stage renal failure worldwide. Calcineurin inhibitors (CNIs) is a selective immunosuppressant widely used in organ transplantation. The ...

    Authors: Yu-Huan Song, Guang-Yan Cai, Yue-Fei Xiao, Yi-Ping Wang, Bao-Shi Yuan, Yuan-Yuan Xia, Si-Yang Wang, Pu Chen, Shu-Wen Liu and Xiang-Mei Chen
    Citation: BMC Nephrology 2017 18:61
    Content type: Research article Published on:

  36. Acute kidney injury (AKI) after cardiac surgery is associated with increased morbidity and mortality. The long-term association between AKI and end-stage renal disease (ESRD) in an Asian population is unknown....

    Authors: Sophia Tsong Huey Chew, Roderica Rui Ge Ng, Weiling Liu, Khuan Yew Chow and Lian Kah Ti
    Citation: BMC Nephrology 2017 18:60
    Content type: Research article Published on:

  37. Elderly patients with advanced chronic kidney disease (CKD) have a high risk of death before reaching end-stage kidney disease. In order to allocate resources, such as advanced care nephrology where it is most...

    Authors: Ulrika Hahn Lundström, Alessandro Gasparini, Rino Bellocco, Abdul Rashid Qureshi, Juan-Jesus Carrero and Marie Evans
    Citation: BMC Nephrology 2017 18:59
    Content type: Research article Published on:

  38. Accurately determining renal function is essential for clinical management of HIV patients. Classically, it has been evaluated by estimating glomerular filtration rate (eGFR) with the MDRD-equation, but today ...

    Authors: M. P. Cristelli, F. Cofán, N. Rico, J. C. Trullàs, C. Manzardo, F. Agüero, J. L. Bedini, A. Moreno, F. Oppenheimer and J. M. Miro
    Citation: BMC Nephrology 2017 18:58
    Content type: Research article Published on:

  40. Pruritus is a common and frustrating symptom in hemodialysis (HD) patients and 5-D itch scale is proposed as a reliable measurement of pruritus. However, information regarding 5-D itch scale categories is curr...

    Authors: Jia-Wen Lai, Hung-Chih Chen, Che-Yi Chou, Hung-Rong Yen, Tsai-Chung Li, Mao-Feng Sun, Hen-Hong Chang, Chiu-Ching Huang, Fuu-Jen Tsai, Johannes Tschen and Chiz-Tzung Chang
    Citation: BMC Nephrology 2017 18:56
    Content type: Research article Published on:

  41. Acute kidney injury (AKI) is diagnosed based on postoperative serum creatinine change, but AKI models have not consistently performed well, in part due to the omission of clinically important but practically u...

    Authors: Loren E. Smith, Derek K. Smith, Jeffrey D. Blume, Edward D. Siew and Frederic T. Billings IV
    Citation: BMC Nephrology 2017 18:55
    Content type: Research article Published on:

  42. Symptomatic hyponatremia is considered a rare complication of oral bowel preparation for colonoscopy. The pathophysiology underlying this phenomenon has been widely regarded as a mere sequela of excessive argi...

    Authors: Martin Windpessl, Christoph Schwarz and Manfred Wallner
    Citation: BMC Nephrology 2017 18:54
    Content type: Case report Published on:

  43. In recent years, early Endothelial Progenitor Cells (eEPCs) have been proven as effective tool in murine ischemic AKI and in diabetic nephropathy. The mechanisms of eEPC-mediated vasoprotection have been eluci...

    Authors: D. Patschan, K. Schwarze, B. Tampe, M. Zeisberg, S. Patschan and G. A. Müller
    Citation: BMC Nephrology 2017 18:53
    Content type: Research article Published on:

  44. When patients experience large weight loss, muscle mass may be affected followed by changes in plasma creatinine (pCr). The MDRD and CKD-EPI equations for estimated GFR (eGFR) include pCr. We hypothesised that...

    Authors: Bernt Johan von Scholten, Frederik Persson, Maria S. Svane, Tine W. Hansen, Sten Madsbad and Peter Rossing
    Citation: BMC Nephrology 2017 18:52
    Content type: Research article Published on:

  45. There are only few cases of renal pathology induced by Lyme borreliosis in the literature, as this damage is rare and uncommon in humans. This patient is the first case of minimal change glomerular disease ass...

    Authors: N. Florens, S. Lemoine, F. Guebre-Egziabher, F. Valour, J. Kanitakis, M. Rabeyrin and L. Juillard
    Citation: BMC Nephrology 2017 18:51
    Content type: Case report Published on:

  46. Cystinuria is an inherited metabolic disease that is caused by defects in two genes, SLC3A1 and SLC7A9, which result in a renal reabsorptive defect of cystine and other dibasic amino acids, including ornithine, a...

    Authors: Abdulrahman Obaid, Marwan Nashabat, Khalid Al Fakeeh, Abdullah T. Al Qahtani and Majid Alfadhel
    Citation: BMC Nephrology 2017 18:50
    Content type: Research article Published on:

  47. Minimal change disease (MCD) and primary focal segmental glomerulosclerosis (FSGS) are glomerular diseases characterized by nephrotic syndrome. Their diagnosis requires a renal biopsy, but it is an invasive pr...

    Authors: Vanessa Pérez, Dolores López, Ester Boixadera, Meritxell Ibernón, Anna Espinal, Josep Bonet and Ramón Romero
    Citation: BMC Nephrology 2017 18:49
    Content type: Research article Published on:

  48. Few studies have investigated the management of human immunodeficiency virus (HIV)-associated end-stage renal failure particularly in low-resource settings with limited access to renal replacement therapy. We ...

    Authors: Kwazi C. Z. Ndlovu, Wilbert Sibanda and Alain Assounga
    Citation: BMC Nephrology 2017 18:48
    Content type: Research article Published on:

  49. Estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR) are renal markers associated with risks of cardiovascular diseases (CVD) and all-cause mortality in diabetic patients. T...

    Authors: Colman Siu Cheung Fung, Eric Yuk Fai Wan, Anca Ka Chun Chan and Cindy Lo Kuen Lam
    Citation: BMC Nephrology 2017 18:47
    Content type: Research article Published on:

  50. Awareness of the spectrum of clinical manifestations of systemic lupus erythematosus (SLE), especially uncommon changes, is essential for diagnosis and effective management of patients.

    Authors: Xiaole Su, Xi Qiao, Jing Li, Lifang Gao, Chen Wang and Lihua Wang
    Citation: BMC Nephrology 2017 18:43
    Content type: Case report Published on:
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BMC Nephrology

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