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  1. End-Stage Renal disease (ESRD) is associated with increased morbidity and mortality. We assessed the occurrence, time-trend and determinants of fatal outcomes of haemodialysis-treated ESRD patients over a 10-y...

    Authors: Marie Patrice Halle, Gloria Ashuntantang, Francois Folefack Kaze, Christian Takongue and Andre-Pascal Kengne
    Citation: BMC Nephrology 2016 17:165
  2. Experimental studies showed that 25-hydroxy-vitamin D [25(OH)D] deficiency (defined as 25-hydroxy-vitamin D < 15 ng/ml) has been associated with CKD progression. Patients with IgA nephropathy have an exception...

    Authors: Xiao-Hua Li, Xin-Ping Huang, Ling Pan, Cheng-Yu Wang, Ju Qin, Feng-Wei Nong, Yu-Zhen Luo, Yue Wu, Yu-Ming Huang, Xi Peng, Zhen-Hua Yang and Yun-Hua Liao
    Citation: BMC Nephrology 2016 17:164
  3. The ISAR study is a prospective, longitudinal, observational cohort study to improve the cardiovascular risk stratification in endstage renal disease (ESRD). The major goal is to characterize the cardiovascula...

    Authors: Christoph Schmaderer, Susanne Tholen, Anna-Lena Hasenau, Christine Hauser, Yana Suttmann, Siegfried Wassertheurer, Christopher C. Mayer, Axel Bauer, Kostantinos D. Rizas, Stephan Kemmner, Konstantin Kotliar, Bernhard Haller, Johannes Mann, Lutz Renders, Uwe Heemann and Marcus Baumann
    Citation: BMC Nephrology 2016 17:161
  4. Endothelial dysfunction is an important precursor to the development of atherosclerosis, and has been suggested to play a role in the increased cardiovascular risk in patients with end stage renal disease. End...

    Authors: Clark Kensinger, Aihua Bian, Meagan Fairchild, Guanhua Chen, Loren Lipworth, T. Alp Ikizler and Kelly A. Birdwell
    Citation: BMC Nephrology 2016 17:160
  5. The true cause of death in severe hyponatraemic patients remains controversial. The present study aimed to analyse the relationship between comorbidity, medical management and prognosis in severe hyponatraemic...

    Authors: Thierry Krummel, Eric Prinz, Marie-Astrid Metten, Claire Borni-Duval, Dorothée Bazin-Kara, Emmanuelle Charlin, Jean-Marc Lessinger and Thierry Hannedouche
    Citation: BMC Nephrology 2016 17:159
  6. Correction of metabolic acidosis (MA) with nutritional therapy or bicarbonate administration is widely used in chronic kidney disease (CKD) patients. However, it is unknown whether these interventions reduce i...

    Authors: Antonio Bellasi, Lucia Di Micco, Domenico Santoro, Stefania Marzocco, Emanuele De Simone, Mario Cozzolino, Luca Di Lullo, Pasquale Guastaferro and Biagio Di Iorio
    Citation: BMC Nephrology 2016 17:158
  7. Patients with end stage renal disease (ESRD), including stage 5 chronic kidney disease (CKD), hemodialysis (HD) and peritoneal dialysis (PD), are at high risk for stroke-related morbidity, mortality and bleedi...

    Authors: Jingwen Tan, Shuiqing Liu, Jodi B. Segal, G. Caleb Alexander and Mara McAdams-DeMarco
    Citation: BMC Nephrology 2016 17:157
  8. Patients with chronic kidney disease (CKD) commonly have unmet information needs. Greater patient participation in healthcare discussions can address these needs and improve health outcomes. We developed a pat...

    Authors: Swati Lederer, Michael J. Fischer, Howard S. Gordon, Anuradha Wadhwa, Subhash Popli and Elisa J. Gordon
    Citation: BMC Nephrology 2016 17:155
  9. It is known that continuous venonenous hemofiltration (CVVH) does not affect the plasma level of neutrophil gelatinase-associated lipocalin (pNGAL) in acute kidney injury (AKI) patients. However, because of th...

    Authors: Xingui Dai, Tao Li, Zhenhua Zeng, Chunlai Fu, Shengbiao Wang, Yeping Cai and Zhongqing Chen
    Citation: BMC Nephrology 2016 17:154
  10. Observational studies have recently associated a decrease in serum parathyroid hormone (PTH) level with a higher rate of mortality among hemodialysis (HD) patients. Decreases in PTH level can result from medic...

    Authors: Guillaume Jean, Jean-Claude Souberbielle, Eric Zaoui, Christie Lorriaux, Jean-Marc Hurot, Brice Mayor, Patrik Deleaval, Manolie Mehdi and Charles Chazot
    Citation: BMC Nephrology 2016 17:153
  11. Whether polyunsaturated fatty acids (PUFA) are associated with end-stage renal disease (ESRD) in populations with a high burden of risk factors for kidney disease is unknown. We sought to determine whether PUF...

    Authors: Rakesh Malhotra, Kerri L. Cavanaugh, William J. Blot, T. Alp Ikizler, Loren Lipworth and Edmond K. Kabagambe
    Citation: BMC Nephrology 2016 17:152
  12. Epidemiological studies have shown an inverse relationship between vitamin D levels and cardiovascular diseases. However, this does not infer a causal relationship between the two. Chronic kidney disease (CKD)...

    Authors: Yong-Muh Ng, Soo-Kun Lim, Pei-San Kang, Khairul Azmi Abdul Kadir and Mei-Ling Sharon Tai
    Citation: BMC Nephrology 2016 17:151
  13. Researchers have developed several equations to predict glomerular filtration rate (GFR) in patients with chronic kidney diseases (CKD). However, there are scarcely any studies performed to discern the best eq...

    Authors: Meixue Chen, Jumei Xia, Guangchang Pei, Ying Zhang, Shuting Wu, Yushuang Qin, Yuanjun Deng, Shuiming Guo, Yanyan Guo, Gang Xu and Min Han
    Citation: BMC Nephrology 2016 17:150
  14. Higher incidence of malignancy and infectious diseases in kidney transplant recipients is related to immunosuppressive treatment after transplantation and the recipient’s native immune system. The complement s...

    Authors: Julia Smedbråten, Geir Mjøen, Anders Hartmann, Anders Åsberg, Halvor Rollag, Tom Eirik Mollnes, Leiv Sandvik, Morten W. Fagerland, Steffen Thiel and Solbjørg Sagedal
    Citation: BMC Nephrology 2016 17:148
  15. Mortality in patients with end-stage renal disorders is often a consequence of cardiovascular complications. Renal replacement therapies may contribute to this morbidity by promoting cellular activation. In re...

    Authors: Gergely Becs, Renáta Hudák, Zsolt Fejes, Ildikó Beke Debreceni, Harjit Pal Bhattoa, József Balla and János Kappelmayer
    Citation: BMC Nephrology 2016 17:147
  16. Several shared common gene networks participate in development of interstinal ganglia and also nephron formation; the glial cell line-derived neurotrophic factor/Ret/glial cell line-derived neurotrophic factor...

    Authors: Keisuke Sugimoto, Tomoki Miyazawa, Hitomi Nishi, Kohei Miyazaki, Takuji Enya, Mitsuru Okada and Tsukasa Takemura
    Citation: BMC Nephrology 2016 17:146
  17. The current standard for induction phase treatment of lupus nephritis is steroid combined with mycophenolate mofetil or pulse intravenous cyclophosphamide (IVC). The lowest dose of IVC recommended for inductio...

    Authors: Mahesh R. Sigdel, Mukunda P. Kafle and Dibya Singh Shah
    Citation: BMC Nephrology 2016 17:145
  18. Vitamin D (25-hydroxyvitamin D; 25[OH]D) deficiency (VDD) is highly prevalent in chronic kidney disease. The aim of this study was to evaluate the effect of oral ergocalciferol supplementation on requirement o...

    Authors: Gaurav Agarwal, Padam Hirachan, Jonathan Gelfond, Paolo Fanti, Claudia Hura and Shweta Bansal
    Citation: BMC Nephrology 2016 17:144
  19. Cardiovascular disease (CVD) is often comorbid with chronic kidney disease (CKD). Small low-density lipoprotein cholesterol (sdLDL-C) has also been found to increase risk for CVD. The goal of the present study...

    Authors: Hao Shen, Yan Xu, Jingfen Lu, Chunfang Ma, Yadong Zhou, Qiong Li, Xu Chen, Ao Zhu and Guorong Shen
    Citation: BMC Nephrology 2016 17:143
  20. To investigate the combined use of intravoxel incoherent motion (IVIM) diffusion-weighted (DW) and blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) to assess rat renal function using a 1.5T...

    Authors: Neil P. Jerome, Jessica K. R. Boult, Matthew R. Orton, James d’Arcy, David J. Collins, Martin O. Leach, Dow-Mu Koh and Simon P. Robinson
    Citation: BMC Nephrology 2016 17:142
  21. The orally administered spherical carbon adsorbent AST-120 is used on-label in Asian countries to slow renal disease progression in patients with progressive chronic kidney disease (CKD). Recently, two multina...

    Authors: Gerald Schulman, Tomas Berl, Gerald J. Beck, Giuseppe Remuzzi, Eberhard Ritz, Miho Shimizu, Yuko Shobu and Mami Kikuchi
    Citation: BMC Nephrology 2016 17:141
  22. Immunotactoid glomerulopathy (ITG) is a rare cause of proteinuria characterized by organized microtubular deposits in the glomerulus. ITG has been associated with underlying lymphoproliferative disorders and a...

    Authors: Aditi Khandelwal, Martina A. Trinkaus, Hassan Ghaffar, Serge Jothy and Marc B. Goldstein
    Citation: BMC Nephrology 2016 17:140
  23. Diabetic nephropathy is the leading cause of end stage kidney disease worldwide. The pathogenesis of this disease remains elusive and multiple factors have been implicated. These include the effects of hypergl...

    Authors: Rosa M. Montero, Gurjeet Bhangal, Charles D. Pusey, Andrew H. Frankel and Frederick W. K. Tam
    Citation: BMC Nephrology 2016 17:139
  24. Low-protein diets (LPD) are an important means of delaying the need for dialysis and attaining a stable metabolic balance in chronic kidney disease (CKD). Many authors consider a low educational level and illi...

    Authors: Stefania Maxia, Valentina Loi, Irene Capizzi, Giorgina Barbara Piccoli, Gianfranca Cabiddu and Antonello Pani
    Citation: BMC Nephrology 2016 17:138
  25. Tumoral calcinosis is a rare manifestation of extraskeletal calcification, featuring large calcified cystic masses in the periarticular regions of large joints. In chronic kidney disease (CKD), this disorder i...

    Authors: Fareed B. Kamar, Bikaramjit Mann and Gregory Kline
    Citation: BMC Nephrology 2016 17:137
  26. Information on acute kidney injury (AKI) in elderly hospitalized patients is limited. This study aims to assess the incidence, risk factors and outcomes of AKI in elderly Chinese patients.

    Authors: Shuwang Ge, Sheng Nie, Zhangsuo Liu, Chunbo Chen, Yan Zha, Jing Qian, Bicheng Liu, Siyuan Teng, Anping Xu, Wei Bin, Xin Xu and Gang Xu
    Citation: BMC Nephrology 2016 17:136
  27. Type 2 diabetes (T2DM) is the leading cause of chronic kidney disease (CKD) in western countries. The combination of both increases the risk of end stage renal disease (ESRD), cardiovascular events and all-cau...

    Authors: Jean-Michel Halimi, Dominique Joly, Christian Combe, Gabriel Choukroun, Bertrand Dussol, Jean-Pierre Fauvel, Stéphane Quéré and Béatrice Fiquet
    Citation: BMC Nephrology 2016 17:135
  28. Little is known about the effect of multiple, or subsequent, ischemic strokes in patients receiving hemodialysis.

    Authors: James B. Wetmore, Jonathan D. Mahnken and Milind A. Phadnis
    Citation: BMC Nephrology 2016 17:134
  29. Long-term outcomes after acute kidney injury (AKI) include incremental loss of function and progression towards chronic kidney disease (CKD); however, the pathogenesis of AKI to CKD remains largely unknown. Cl...

    Authors: Jia Guo, Qiunong Guan, Xiuheng Liu, Hao Wang, Martin E. Gleave, Christopher Y. C. Nguan and Caigan Du
    Citation: BMC Nephrology 2016 17:133
  30. Pregnancy in women with advanced CKD becoming increasingly common. However, experience with low-protein diets in CKD patients in pregnancy is still limited.

    Authors: Rossella Attini, Filomena Leone, Silvia Parisi, Federica Fassio, Irene Capizzi, Valentina Loi, Loredana Colla, Maura Rossetti, Martina Gerbino, Stefania Maxia, Maria Grazia Alemanno, Fosca Minelli, Ettore Piccoli, Elisabetta Versino, Marilisa Biolcati, Paolo Avagnina…
    Citation: BMC Nephrology 2016 17:132
  31. Native arteriovenous fistula (AVF) is the most appropriate type of vascular access for chronic dialysis. Its patency rates depend on vascular wall characteristics. Ketoacid analogues of essential amino acids (...

    Authors: Cristiana David, Ileana Peride, Andrei Niculae, Alexandra Maria Constantin and Ionel Alexandru Checherita
    Citation: BMC Nephrology 2016 17:131
  32. Acute kidney injury (AKI) has been associated with high morbidity and mortality rates among critically ill children. Cystatin C is a protease inhibitor, and studies have shown that it is a promising marker for...

    Authors: Osama Y. Safdar, Mohammed Shalaby, Norah Khathlan, Bassem Elattal, Mohammed Bin Joubah, Esraa Bukahri, Mafaza Saber, Arwa Alahadal, Hala Aljariry, Safaa Gasim, Afnan Hadadi, Abdullah Alqahtani, Roaa Awleyakhan and Jameela A. Kari
    Citation: BMC Nephrology 2016 17:130
  33. Nutrition has been an important part of medical management in patients with chronic kidney disease for more than a century. Since the 1970s, due to technological advances in renal replacement therapy (RRT) suc...

    Authors: Maria Chan
    Citation: BMC Nephrology 2016 17:129
  34. Hypertension and proteinuria are critically involved in the progression of chronic kidney disease. Despite treatment with renin angiotensin system inhibition, kidney function declines in many patients. Aldoste...

    Authors: Gemma Currie, Alison H. M. Taylor, Toshiro Fujita, Hiroshi Ohtsu, Morten Lindhardt, Peter Rossing, Lene Boesby, Nicola C. Edwards, Charles J. Ferro, Jonathan N. Townend, Anton H. van den Meiracker, Mohammad G. Saklayen, Sonia Oveisi, Alan G. Jardine, Christian Delles, David J. Preiss…
    Citation: BMC Nephrology 2016 17:127
  35. Cameroon is a low–middle income country with a rich diversity of culture and cuisine. Chronic kidney disease (CKD) is common in Cameroon and over 80 % of patients present late for care, precluding the use of t...

    Authors: Gloria Enow Ashuntantang, Hermine Fouda, Francois Folefack Kaze, Marie-Patrice Halle, Crista Tabi-Arrey and Magloire Biwole-Sida
    Citation: BMC Nephrology 2016 17:126
  36. Collapsing Glomerulopathy (CG), also known as the collapsing variant of Focal Segmental Glomerulosclerosis (FSGS), is distinct in both its clinical severity and its pathophysiologic characteristics from other ...

    Authors: Whitney Besse, Sherry Mansour, Karan Jatwani, Cynthia C. Nast and Ursula C. Brewster
    Citation: BMC Nephrology 2016 17:125
  37. Dietary treatment is helpful in CKD patients, but nutritional interventions are scarcely implemented. The main concern of the renal diets is its feasibility with regards to daily clinical practice especially i...

    Authors: Adamasco Cupisti, Claudia D’Alessandro, Biagio Di Iorio, Anna Bottai, Claudia Zullo, Domenico Giannese, Massimiliano Barsotti and Maria Francesca Egidi
    Citation: BMC Nephrology 2016 17:124
  38. Restriction of dietary sodium is routinely recommended for patients with chronic kidney disease (CKD). Whether or not sodium intake is associated with the progression of CKD and mortality remains controversial...

    Authors: Andrea Mazarova, Amber O. Molnar, Ayub Akbari, Manish M. Sood, Swapnil Hiremath, Kevin D. Burns, Timothy O. Ramsay, Ranjeeta Mallick, Gregory A. Knoll and Marcel Ruzicka
    Citation: BMC Nephrology 2016 17:123
  39. A link between IgA nephropathy and Crohn’s disease has recently been reported. Other researchers hypothesize that intestine-derived IgA complexes deposit in glomerular mesangial cells, eliciting IgA nephropath...

    Authors: Tomohiro Terasaka, Haruhito A. Uchida, Ryoko Umebayashi, Keiko Tsukamoto, Keiko Tanaka, Masashi Kitagawa, Hitoshi Sugiyama, Hiroaki Tanioka and Jun Wada
    Citation: BMC Nephrology 2016 17:122
  40. Chronic kidney disease (CKD) is a global health burden, yet it is still underrepresented within public health agendas in many countries. Studies focusing on the natural history of CKD are challenging to design...

    Authors: Thomas Dienemann, Naohiko Fujii, Paula Orlandi, Lisa Nessel, Susan L. Furth, Wendy E. Hoy, Seiichi Matsuo, Gert Mayer, Shona Methven, Franz Schaefer, Elke S. Schaeffner, Laura Solá, Bénédicte Stengel, Christoph Wanner, Luxia Zhang, Adeera Levin…
    Citation: BMC Nephrology 2016 17:121
  41. Hemodiafiltration with on-line endogenous reinfusion (HFR) is an extracorporeal dialytic method that combines diffusion, convection and adsorption. HFR-Supra (HFR-S) is a second-generation system with increase...

    Authors: Simonetta Palleschi, Paolo M. Ghezzi, Giuseppe Palladino, Barbara Rossi, Marino Ganadu, Domenica Casu, Maria Cossu, Giovanni Mattana, Antonio Maria Pinna, Bruno Contu, Tonina Ghisu, Alessandro Monni, Luana Gazzanelli, Maria Cristina Mereu, Franco Logias, Mario Passaghe…
    Citation: BMC Nephrology 2016 17:120
  42. Citrate, the currently preferred anticoagulant for continuous veno-venous hemofiltration (CVVH), may influence acid-base equilibrium.

    Authors: Rita Jacobs, Patrick M. Honore, Marc Diltoer and Herbert D. Spapen
    Citation: BMC Nephrology 2016 17:119

    The Correction to this article has been published in BMC Nephrology 2020 21:105

  43. Despite the growing incidence of acute kidney injury (AKI) worldwide, there is little data on the burden and outcomes of AKI in intensive care unit (ICU) in low resource settings. The present study assessed th...

    Authors: Angèle Masewu, Jean-Robert Makulo, François Lepira, Eric Bibonge Amisi, Ernest Kiswaya Sumaili, Justine Bukabau, Vieux Mokoli, Augustin Longo, Yannick Nlandu, Yannick Engole, Cedric Ilunga, Alphonse Mosolo, Alex Ngalala, Justin Kazadi, Richard Mvuala, Jackson Athombo…
    Citation: BMC Nephrology 2016 17:118
  44. Until now, no long-term studies relating serum albumin level to mortality rate in prevalent haemodialysis (HD) patients have been conducted. We aimed to examine the association between serum albumin level and ...

    Authors: Jin-Bor Chen, Ben-Chung Cheng, Cheng-Hong Yang and Moi-Sin Hua
    Citation: BMC Nephrology 2016 17:117
  45. Neurotoxicity is a common side effect of treatment with calcineurin inhibitors. Tremors are frequently reported as the most common manifestation. Variable presentations can include headaches, seizures, visual ...

    Authors: Ashwani K. Gupta and Nader Bahri
    Citation: BMC Nephrology 2016 17:116

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