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  1. This study was performed to evaluate the clinical effectiveness of alternative strategies for the prevention and treatment of patients with chronic kidney disease undergoing peritoneal dialysis and colonized by S...

    Authors: Cibele Grothe, Mônica Taminato, Angélica Belasco, Ricardo Sesso and Dulce Barbosa
    Citation: BMC Nephrology 2016 17:115
  2. The regulation of fibroblast growth factor-23 (FGF23) secretion in patients with chronic kidney disease (CKD) is incompletely understood. An in vitro study showed that metabolic acidosis increased FGF23 in mouse ...

    Authors: Wei Chen, Michal L. Melamed, Thomas H. Hostetter, Carolyn Bauer, Amanda C. Raff, Anthony L. Almudevar, Amy Lalonde, Susan Messing and Matthew K. Abramowitz
    Citation: BMC Nephrology 2016 17:114
  3. Chronic kidney disease (CKD) and end-stage-kidney disease (ESKD) continue to be under-diagnosed and a major burden for Aboriginal communities in central Australia. The aim of this study was to examine the risk...

    Authors: Rebecca Ritte, Joanne Luke, Craig Nelson, Alex Brown, Kerin O’Dea, Alicia Jenkins, James D. Best, Robyn McDermott, Mark Daniel and Kevin Rowley
    Citation: BMC Nephrology 2016 17:113
  4. Acute interstitial nephritis secondary to proton pump inhibitors (PPIs) frequently goes undiagnosed due to its subacute clinical presentation, which may later present as chronic kidney disease (CKD). We invest...

    Authors: Pradeep Arora, Anu Gupta, Mojgan Golzy, Nilang Patel, Randolph L. Carter, Kabir Jalal and James W. Lohr
    Citation: BMC Nephrology 2016 17:112
  5. As a result of difficulties related to their illness, diagnosis and treatment, patients with end-stage renal disease experience significant emotional and psychological problems, which untreated can have consid...

    Authors: Francesca Taylor, Celia Taylor, Jyoti Baharani, Johann Nicholas and Gill Combes
    Citation: BMC Nephrology 2016 17:111
  6. Transcription factor Nrf2 protects from experimental acute kidney injury (AKI) and is promising to limit progression in human chronic kidney disease (CKD) by upregulating multiple antioxidant genes. We recentl...

    Authors: Sanjeev Noel, Lois J. Arend, Samatha Bandapalle, Sekhar P. Reddy and Hamid Rabb
    Citation: BMC Nephrology 2016 17:110
  7. Fluid overload is frequently found in acute kidney injury patients in critical care units. Recent studies have shown the relationship of fluid overload with adverse outcomes; hence, manage and optimization of ...

    Authors: Rolando Claure-Del Granado and Ravindra L. Mehta
    Citation: BMC Nephrology 2016 17:109
  8. Kidney transplantation (KTx) disparity is a significant problem in the United States, particularly in the Southeastern region. In response to this phenomenon, the Southeastern Kidney Transplant Coalition was c...

    Authors: Teri Browne, Ahinee Amamoo, Rachel E. Patzer, Jenna Krisher, Henry Well, Jennifer Gander and Stephen O. Pastan
    Citation: BMC Nephrology 2016 17:108
  9. Increasing the weekly frequency of hemodialysis sessions has positive effects, on the control of several biological data of patients. However, knowledge about Daily HemoDialysis (DHD) practices is limited in F...

    Authors: Adélaïde Pladys, Sahar Bayat, Anne Kolko, Clémence Béchade, Cécile Couchoud and Cécile Vigneau
    Citation: BMC Nephrology 2016 17:107
  10. New-onset diabetes mellitus after transplantation (NODAT) is a serious complication following renal transplantation. The aim of this study was to identify the risk factors for the development of NODAT in Korea...

    Authors: Hoon Yu, Hyosang Kim, Chung Hee Baek, Seung Don Baek, Soomin Jeung, Duck Jong Han and Su-Kil Park
    Citation: BMC Nephrology 2016 17:106
  11. Chronic kidney disease (CKD) is an emerging health public problem in Brazil. Nutritional counseling with focus on protein restriction is a promising strategy to treatment of nondialysis CKD patients due its ef...

    Authors: Denise Mafra and Viviane O. Leal
    Citation: BMC Nephrology 2016 17:105
  12. Evidence on the role of plasma exchange for treating recurrent post-transplant focal segmental glomerulosclerosis (FSGS) comes largely from individual cases and uncontrolled series. We conducted a systematic r...

    Authors: Abdullah Kashgary, Jessica M. Sontrop, Lihua Li, Ahmed A. Al-Jaishi, Zainab N. Habibullah, Roaa Alsolaimani and William F. Clark
    Citation: BMC Nephrology 2016 17:104
  13. Predialysis nephrology care is associated with lower mortality and rates of hospitalization following chronic dialysis initiation. Whether more frequent predialysis nephrology care is associated with other fav...

    Authors: Michael J. Fischer, Kevin T. Stroupe, James S. Kaufman, Ann M. O’Hare, Margaret M. Browning, Min-Woong Sohn, Zhiping Huo and Denise M. Hynes
    Citation: BMC Nephrology 2016 17:103
  14. Evidence exists that nutritional therapy induces favorable metabolic changes, prevents signs and symptoms of renal insufficiency, and is able to delay the need of dialysis. Currently, the main concern of the r...

    Authors: Claudia D’Alessandro, Giorgina Barbara Piccoli, Patrizia Calella, Giuliano Brunori, Franca Pasticci, Maria Francesca Egidi, Irene Capizzi, Vincenzo Bellizzi and Adamasco Cupisti
    Citation: BMC Nephrology 2016 17:102
  15. The clinic-pathological features and outcomes of Chinese patients with antineutrophil cytoplasmic autoantibody (ANCA)-positive eosinophilic granulomatosis with polyangiitis (EGPA) and renal involvement have no...

    Authors: Yinghua Chen, Yuemei Ding, Zhengzhao Liu, Haitao Zhang, Zhihong Liu and Weixin Hu
    Citation: BMC Nephrology 2016 17:101
  16. Acute kidney injury (AKI) affects 3–7 % of patients admitted to the hospital and approximately 25–30 % of patients in the intensive care unit. RIFLE, a newly developed international consensus classification fo...

    Authors: Richard K. D. Ephraim, Kwame O. Darkwah, Samuel A. Sakyi, Mabel Ephraim, Enoch O. Antoh and Prince Adoba
    Citation: BMC Nephrology 2016 17:99
  17. Disruption of ROBO2 in humans causes vesicoureteral reflux (VUR)/congenital anomalies of the kidney and urinary tract (CAKUT). PiggyBac (PB) is a DNA transposon, and its insertion often reduces—but does not elimi...

    Authors: Jialu Liu, Li Sun, Qian Shen, Xiaohui Wu and Hong Xu
    Citation: BMC Nephrology 2016 17:98
  18. Deteriorating renal function in chronic kidney disease (CKD) patients is commonly associated with reduced haemoglobin levels, adding to the already considerable humanistic burden of CKD. This analysis evaluate...

    Authors: Daniel Eriksson, David Goldsmith, Siguroli Teitsson, James Jackson and Floortje van Nooten
    Citation: BMC Nephrology 2016 17:97
  19. The aims of this study are to find the prevalence of potential drug-drug interactions (DDIs) in patients with Hemodialysis and identify factors associated with these interactions if present.

    Authors: Rowa’ Al-Ramahi, Afnan R. Raddad, Alaa O. Rashed, Amneh Bsharat, Dania Abu-Ghazaleh, Eman Yasin and Oraina Shehab
    Citation: BMC Nephrology 2016 17:96
  20. The extent to which smoking contributes to adverse outcomes among men and women of all ages undergoing dialysis is uncertain. The objective of this study was to determine the differential impact of smoking on ...

    Authors: Austin G. Stack, Darya Yermak, David G. Roche, John P. Ferguson, Mohamed Elsayed, Waleed Mohammed, Liam F. Casserly, Stewart R. Walsh and Cornelius J. Cronin
    Citation: BMC Nephrology 2016 17:95
  21. Health related quality of life (HRQOL) is patient-reported, and an important treatment outcome for patients undergoing renal replacement therapy. Whether HRQOL in dialysis can affect mortality or graft surviva...

    Authors: Nanna von der Lippe, Bård Waldum-Grevbo, Anna Varberg Reisæter and Ingrid Os
    Citation: BMC Nephrology 2016 17:94
  22. A lack of advanced healthcare information systems and validated scientific cohorts in Nicaragua makes it difficult to estimate disease prevalences and other public health statistics. Although there is concern ...

    Authors: Kailey Minnings, Madeline Fiore, Martha Mosco, Ryan Ferguson, Sarah Leatherman, Eric Kerns, James Kaufman, Melissa Fiore, Daniel Brooks, Juan Jose Amador, Hillary Paulsen, Zachary Ernstberger, Bricia Trejo, Elyse Sullivan, Amos Lichtman, Keriann Nobil…
    Citation: BMC Nephrology 2016 17:93
  23. Chronic kidney disease (CKD) amounts to a heavy burden for health services. There is no long-running epidemiological tool for CKD before dialysis. We here present the protocol for a cohort of patients with “no...

    Authors: Jacques Massol, Gérard Janin, Camille Bachot, Christophe Gousset, Geoffroy Sainte-Claire Deville and Jean-Marc Chalopin
    Citation: BMC Nephrology 2016 17:92
  24. The first government funded and sustainable dialysis unit was established in Ethiopia at Saint Paul’s Hospital Millennium Medical College (SPHMMC). This has led to the development of a unique cohort of patient...

    Authors: Ahmed Ibrahim, Momina M. Ahmed, Seman Kedir and Delayehu Bekele
    Citation: BMC Nephrology 2016 17:91
  25. Whereas in many parts of the world a low protein diet (LPD, 0.6-0.8 g/kg/day) is routinely prescribed for the management of patients with non-dialysis-dependent chronic kidney disease (CKD), this practice is i...

    Authors: Kamyar Kalantar-Zadeh, Linda W. Moore, Amanda R. Tortorici, Jason A. Chou, David E. St-Jules, Arianna Aoun, Vanessa Rojas-Bautista, Annelle K. Tschida, Connie M. Rhee, Anuja A. Shah, Susan Crowley, Joseph A. Vassalotti and Csaba P. Kovesdy
    Citation: BMC Nephrology 2016 17:90
  26. This review provides an overview of the development, implementation and practise of low protein diets (LPD) in Sweden. While the current practice is discussed in general terms emphasizing the interplay between...

    Authors: Sintra Eyre, Gerd Faxén-Irving, Per-Ola Attman, Marie Evans, Karin Windahl, Sigrid Wegener, Charlotte Andersén, Karin Nykvist-Raanaes, Sara Einemo and Juan-Jesus Carrero
    Citation: BMC Nephrology 2016 17:89
  27. Diabetic kidney disease, a global health issue, remains associated with high morbidity and mortality. Previous research has shown that multidisciplinary management of chronic disease can improve patient outcom...

    Authors: Nancy Helou, Dominique Talhouedec, Maya Shaha and Anne Zanchi
    Citation: BMC Nephrology 2016 17:88
  28. Erythropoiesis-stimulating agents (ESAs) are commonly used for the treatment of anemia due to chronic kidney disease (CKD) and end stage renal disease (ESRD). Patients often lack an understanding of the potent...

    Authors: Lauren B. Beach, Marcus Wild, Gowri Ramachandran, H. Omer Ikizler and Kerri L. Cavanaugh
    Citation: BMC Nephrology 2016 17:86
  29. This paper describes the 30-year experience on nutritional management of non-dialysis dependent chronic kidney disease (CKD) patients in a public outpatient clinic located in the city of São Paulo, Brazil. A t...

    Authors: Lilian Cuppari, Fabiana Baggio Nerbass, Carla Maria Avesani and Maria Ayako Kamimura
    Citation: BMC Nephrology 2016 17:85
  30. Among adult kidney transplant recipients, non-adherence to immunosuppressive medications is the leading predictor of poor outcomes, including rejection, kidney loss, and death. An alarming one-third of kidney ...

    Authors: Cynthia L. Russell, Shirley Moore, Donna Hathaway, An-Lin Cheng, Guoqing Chen and Kathy Goggin
    Citation: BMC Nephrology 2016 17:84
  31. The global pediatric nephrology workforce is poorly characterized. The objectives of our study were to assess pediatric nephrologists’ perceptions of the adequacy of the pediatric nephrology workforce, and und...

    Authors: Dorey Glenn, Sophie Ocegueda, Meaghan Nazareth, Yi Zhong, Adam Weinstein, William Primack, Pierre Cochat and Maria Ferris
    Citation: BMC Nephrology 2016 17:83
  32. Impairment in glomerular endothelial function likely plays a major role in the development of albuminuria and CKD progression. Glomerular endothelial dysfunction may reflect systemic microvascular dysfunction,...

    Authors: Stephen L. Seliger, Shabnam Salimi, Valerie Pierre, Jamie Giffuni, Leslie Katzel and Afshin Parsa
    Citation: BMC Nephrology 2016 17:82
  33. Renal biopsy is not free from complications and patients who undergo this procedure are usually hospitalized to receive intensive care for several days after biopsy. In contrast, after this period, routine fol...

    Authors: Takuya Murakami, Shin-ichi Takeda, Hidenori Kanazawa, Atsushi Ugajin, Shigeyoshi Kijima, Hiroyasu Nakamura, Toshimi Imai, Taro Sugase, Ryoko Horikoshi, Takahisa Kobayashi, Tetsu Akimoto, Osamu Saito and Daisuke Nagata
    Citation: BMC Nephrology 2016 17:81
  34. Haemodialysis (HD) is one of the life-saving options for patients with end stage renal disease but demand for this treatment exceeds capacity in publicly funded hospitals. One novel approach to addressing this...

    Authors: Julie Y. Chen, Eric Y. F. Wan, Karina H. Y. Chan, Anca K. C. Chan, Frank W. K. Chan and Cindy L. K. Lam
    Citation: BMC Nephrology 2016 17:79
  35. Although sudden cardiac death (SCD) is recognized as a distinct cause of death in patients with end stage renal disease (ESRD), its incidence has not been well summarized.

    Authors: Sharanya Ramesh, Ann Zalucky, Brenda R. Hemmelgarn, Derek J. Roberts, Sofia B. Ahmed, Stephen B. Wilton and Min Jun
    Citation: BMC Nephrology 2016 17:78
  36. Nutritional treatment has always represented a major feature of CKD management. Over the decades, the use of nutritional treatment in CKD patients has been marked by several goals. The first of these include t...

    Authors: Vincenzo Bellizzi, Adamasco Cupisti, Francesco Locatelli, Piergiorgio Bolasco, Giuliano Brunori, Giovanni Cancarini, Stefania Caria, Luca De Nicola, Biagio R. Di Iorio, Lucia Di Micco, Enrico Fiaccadori, Giacomo Garibotto, Marcora Mandreoli, Roberto Minutolo, Lamberto Oldrizzi, Giorgina B. Piccoli…
    Citation: BMC Nephrology 2016 17:77
  37. Dietary therapy represents an important tool in the management of chronic kidney disease (CKD), mainly through a balanced reduction of protein intake aimed at giving the remnant nephrons in damaged kidneys a “...

    Authors: Giorgina Barbara Piccoli, Irene Capizzi, Federica Neve Vigotti, Filomena Leone, Claudia D’Alessandro, Domenica Giuffrida, Marta Nazha, Simona Roggero, Nicoletta Colombi, Giuseppe Mauro, Natascia Castelluccia, Adamasco Cupisti and Paolo Avagnina
    Citation: BMC Nephrology 2016 17:76
  38. Although elevated body mass index (BMI) is a predictor of better clinical outcomes in dialysis patients, the evidence in pre-dialysis chronic kidney disease (CKD) is conflicting. Clinical measures of central o...

    Authors: Emma Davis, Katrina Campbell, Glenda Gobe, Carmel Hawley, Nicole Isbel and David W. Johnson
    Citation: BMC Nephrology 2016 17:74
  39. Patients with end-stage renal disease (ESRD) commonly suffer from severe fatigue, which strongly impacts their quality of life (QoL). Although fatigue is often attributed to disease- and treatment characterist...

    Authors: Wieke E. van der Borg, Karen Schipper and Tineke A. Abma
    Citation: BMC Nephrology 2016 17:73
  40. Functional impairment is associated with adverse outcomes in older people, as well as in patients on chronic hemodialysis. The aim of the present study was to determine the characteristics associated with func...

    Authors: Maurizio Bossola, Enrico Di Stasio, Manuela Antocicco, Gilda Pepe, Luigi Tazza, Giuseppe Zuccalà and Alice Laudisio
    Citation: BMC Nephrology 2016 17:72
  41. Replacing carbohydrate with protein acutely increases glomerular filtration rate (GFR) but is associated with faster, long-term kidney disease progression. The effects of carbohydrate type (i.e. glycemic index...

    Authors: Stephen P. Juraschek, Alex R. Chang, Lawrence J. Appel, Cheryl A. M. Anderson, Deidra C. Crews, Letitia Thomas, Jeanne Charleston and Edgar R. Miller III
    Citation: BMC Nephrology 2016 17:70
  42. There is emerging evidence that exercise training could positively impact several of the cardiovascular risk factors associated with sudden cardiac death amongst patients on haemodialysis. The primary aim of t...

    Authors: M. P. M. Graham-Brown, D. S. March, D. R. Churchward, H. M. L. Young, M. Dungey, S. Lloyd, N. J. Brunskill, A. C. Smith, G. P. McCann and J. O. Burton
    Citation: BMC Nephrology 2016 17:69
  43. The multi-racial and multi-ethnic population of South Africa has significant variation in their nutritional habits with many black South Africans undergoing a nutritional transition to Western type diets. In t...

    Authors: Oluwatoyin I. Ameh, Lynette Cilliers and Ikechi G. Okpechi
    Citation: BMC Nephrology 2016 17:68
  44. Low protein diets (LPD) have long been prescribed to chronic kidney disease patients with the goals of improving metabolic abnormalities and postpone the start of maintenance dialysis.

    Authors: Denis Fouque, Jing Chen, Wei Chen, Liliana Garneata, SJ Hwang, Kamyar Kalantar-Zadeh, Joel D. Kopple, William E. Mitch, Giorgina Piccoli, Vladimir Teplan and Philippe Chauveau
    Citation: BMC Nephrology 2016 17:63
  45. Haemodialysis in Malawi consumes a disproportionate amount of the national health budget, costing approximately $20,000 per patient per year. Adjunctive therapeutic agents for end stage kidney disease and labo...

    Authors: Thokozani Masina, Bernadette Chimera, Martin Kamponda and Gavin Dreyer
    Citation: BMC Nephrology 2016 17:61

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