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  1. Warfarin related nephropathy is one of the potential complications of warfarin therapy. Despite the well described histological entity, the clinical course and approach to warfarin related nephropathy in patie...

    Authors: Chee Yong Ng, Chieh Suai Tan, Chee Tang Chin, See Lim Lim, Ling Zhu, Keng Thye Woo and Puay Hoon Tan
    Citation: BMC Nephrology 2016 17:15
  2. The benefits of live donor kidney transplantation must be balanced against the potential harm to the donor. Well-designed prospective studies are needed to study the long-term consequences of kidney donation.

    Authors: Shiromani Janki, Karel W. J. Klop, Hendrikus J. A. N. Kimenai, Jacqueline van de Wetering, Willem Weimar, Emma K. Massey, Abbas Dehghan, Dimitris Rizopoulos, Henry Völzke, Albert Hofman and Jan N. M. Ijzermans
    Citation: BMC Nephrology 2016 17:14
  3. Anemia is common among patients with chronic kidney disease (CKD) but its health consequences are poorly defined. The aim of this study was to determine the relationship between anemia and cognitive decline in...

    Authors: Manjula Kurella Tamura, Eric Vittinghoff, Jingrong Yang, Alan S. Go, Stephen L. Seliger, John W. Kusek, James Lash, Debbie L. Cohen, James Simon, Vecihi Batuman, Juan Ordonez, Gail Makos and Kristine Yaffe
    Citation: BMC Nephrology 2016 17:13
  4. It is uncertain whether switching to frequent nocturnal hemodialysis improves cognitive function in well-dialyzed patients and how this compares to patients who receive a kidney transplant.

    Authors: Bradley S. Dixon, John M. VanBuren, James R. Rodrigue, Robert S. Lockridge, Robert Lindsay, Christopher Chan, Michael V. Rocco, Jacob J. Oleson, Leigh Beglinger, Kevin Duff, Jane S. Paulsen and John B. Stokes
    Citation: BMC Nephrology 2016 17:12
  5. Treatment of end stage renal disease has an impact on patients’ physical and psychological health, including quality of life (QoL). Nowadays, it is known that reducing the dialysis period has many advantages r...

    Authors: Véronique Sébille, Jean-Benoit Hardouin, Magali Giral, Angélique Bonnaud-Antignac, Philippe Tessier, Emmanuelle Papuchon, Alexandra Jobert, Elodie Faurel-Paul, Stéphanie Gentile, Elisabeth Cassuto, Emmanuel Morélon, Lionel Rostaing, Denis Glotz, Rebecca Sberro-Soussan, Yohann Foucher and Aurélie Meurette
    Citation: BMC Nephrology 2016 17:11
  6. Many metabolic changes develop in patients with chronic kidney disease which often necessitate frequent biochemical analysis of blood. Saliva analysis as an alternative to blood has many advantages. The aims o...

    Authors: Taye Jemilat Lasisi, Yemi Raheem Raji and Babatunde Lawal Salako
    Citation: BMC Nephrology 2016 17:10
  7. The patterns, performance characteristics, and yield of diagnostic tests ordered for the evaluation of acute kidney injury (AKI) have not been rigorously evaluated.

    Authors: David E. Leaf, Anand Srivastava, Xiaoxi Zeng, Gearoid M. McMahon, Heather E. Croy, Mallika L. Mendu, Allen Kachalia and Sushrut S. Waikar
    Citation: BMC Nephrology 2016 17:9
  8. The wide use of healthy persons as kidney donors calls for awareness of risks associated with donation. Live kidney donation may impair quality of life (QOL) and result in fatigue. Long-term data on these issu...

    Authors: Käthe Meyer, Astrid Klopstad Wahl, Ida Torunn Bjørk, Torbjørn Wisløff, Anders Hartmann and Marit Helen Andersen
    Citation: BMC Nephrology 2016 17:8
  9. Membranoproliferative glomerulonephritis (MPGN) is an uncommon glomerular disorder that may lead to end stage renal disease (ESRD). With new understanding of the disease pathogenesis, the classical classificat...

    Authors: Sami Alasfar, Naima Carter-Monroe, Avi Z. Rosenberg, Robert A. Montgomery and Nada Alachkar
    Citation: BMC Nephrology 2016 17:7
  10. Baseline serum creatinine (SCr) level is frequently not measured in clinical practice. The aim of this study was to investigate the effect of various methods of baseline SCr determination measurement on accura...

    Authors: Charat Thongprayoon, Wisit Cheungpasitporn, Andrew M. Harrison, Wonngarm Kittanamongkolchai, Patompong Ungprasert, Narat Srivali, Abbasali Akhoundi and Kianoush B. Kashani
    Citation: BMC Nephrology 2016 17:6
  11. Recent studies indicate that mural cells of the preglomerular vessels, known as cells of renin lineage (CoRL), contribute to repair and regeneration of injured kidney glomeruli. However, their potential roles ...

    Authors: Ania Stefanska, Diana Eng, Natalya Kaverina, Jeffrey W. Pippin, Kenneth W. Gross, Jeremy S. Duffield and Stuart J. Shankland
    Citation: BMC Nephrology 2016 17:5
  12. Hemophagocytic lymphohistiocytosis (HLH) is a fatal clinical syndrome characterized by excessive immune activation and inflammation. It is frequently complicated by acute kidney injury (AKI) that often develop...

    Authors: Myoung Nam Bae, Dae Hun Kwak, Se Jun Park, Bum Soon Choi, Cheol Whee Park, Yeong Jin Choi, Jong Wook Lee, Chul Woo Yang, Yong-Soo Kim and Byung Ha Chung
    Citation: BMC Nephrology 2016 17:4
  13. Lower serum bicarbonate, mainly due to the modern Western-style diet, and renal hyperfiltration (RHF) are both independently associated with higher mortality in the general population with preserved renal func...

    Authors: Minseon Park, Rina So, Kwon Wook Joo and Hyung-Jin Yoon
    Citation: BMC Nephrology 2016 17:3
  14. Although dysnatremia has been reported to be correlated with mortality risk, this issue remains unresolved in patients undergoing continuous renal replacement therapy (CRRT). Furthermore, it has not been deter...

    Authors: Seung Seok Han, Eunjin Bae, Dong Ki Kim, Yon Su Kim, Jin Suk Han and Kwon Wook Joo
    Citation: BMC Nephrology 2016 17:2
  15. Encapsulating peritoneal sclerosis (EPS) is classically described as progressive sclerosis and cocooning of the entire peritoneum; however, there has been limited number of reported cases of localized fibrosis...

    Authors: Sassan Ghazan-Shahi and Joanne M. Bargman
    Citation: BMC Nephrology 2016 17:1
  16. Maintaining optimal fluid balance is essential in haemodialysis (HD) patients but clinical evaluation remains problematic. Other technologies such as bioimpedance are emerging as valuable adjuncts. This study ...

    Authors: Murugan Sivalingam, Enric Vilar, Suresh Mathavakkannan and Ken Farrington
    Citation: BMC Nephrology 2015 16:218
  17. Autosomal dominant inheritance of congenital nephrogenic diabetes insipidus (CNDI) is rare and usually caused by variations in the AQP2 gene. We have investigated the genetic and molecular background underlying s...

    Authors: Pia Dollerup, Troels Møller Thomsen, Lene N. Nejsum, Mia Færch, Martin Österbrand, Niels Gregersen, Søren Rittig, Jane H. Christensen and Thomas J. Corydon
    Citation: BMC Nephrology 2015 16:217
  18. The objective of this article is to describe the organisation of an international, clinical registry, the Chronic Kidney Disease Observational Database (CKDOD), the processes of enrolling patients and entering...

    Authors: Bharat Shah, Ashok Kirpalani, Sham Sunder, Ashwani Gupta, Umesh Khanna, Deodatta Chafekar, Li Ping Tan, Dhavee Sirivongs, Dilip Pahari, Gokul Nath and Talat Alp Ikizler
    Citation: BMC Nephrology 2015 16:215
  19. Some nephrologists have advocated an individualized approach to the prescription of bicarbonate hemodialysis. However, the utility of monthly serum bicarbonate levels for guiding and evaluating such treatment ...

    Authors: Ravi Patel, William Paredes, Charles B. Hall, Mark A. Nader, Deepak Sapkota, Vaughn W. Folkert and Matthew K. Abramowitz
    Citation: BMC Nephrology 2015 16:214
  20. Reports on the histopathology of childhood nephrotic syndrome (NS) had emanated from our Centre since the 1960s and by the late 1980s and early 1990s, a change was observed and reported. Taking into considerat...

    Authors: Adanze O. Asinobi, Adebowale D. Ademola, Clement A. Okolo and Joseph O. Yaria
    Citation: BMC Nephrology 2015 16:213
  21. Pyrrolidine dithiocarbamate (PDTC) reduces renal cyst growth in a rodent model of polycystic kidney disease (PKD) but the mechanism of action is not clear. Here, we investigated the hypothesis that PDTC reduce...

    Authors: Michelle H. T. Ta, David Liuwantara and Gopala K. Rangan
    Citation: BMC Nephrology 2015 16:212
  22. Few studies have focused on investigating hypoalbuminemia in patients during earlier stages of chronic kidney disease (CKD). In particular, little is known about the role of gastrointestinal (GI) symptoms. Our...

    Authors: Xuehan Zhang, Nisha Bansal, Alan S. Go and Chi-yuan Hsu
    Citation: BMC Nephrology 2015 16:211
  23. The role of uric acid in development of renal dysfunction (RD) remains controversial. Earlier studies have reported inconsistent results, possibly because of their varying ability to adjust for confounding. Th...

    Authors: Hilde M. Storhaug, Ingrid Toft, Jon Viljar Norvik, Trond Jenssen, Bjørn O. Eriksen, Toralf Melsom, Maja-Lisa Løchen and Marit Dahl Solbu
    Citation: BMC Nephrology 2015 16:210
  24. Percutaneous renal biopsy (PRB) is an important diagnostic procedure. Despite advances in its safety profile there remains a small but significant risk of bleeding complications. Traditionally, operators train...

    Authors: Scott W. Oliver, Rajan K. Patel, Khalid A. Ali, Colin C. Geddes and Bruce MacKinnon
    Citation: BMC Nephrology 2015 16:209
  25. Atypical hemolytic uremic syndrome (aHUS) is a rare, genetically-mediated systemic disease most often caused by chronic, uncontrolled complement activation that leads to systemic thrombotic microangiopathy (TM...

    Authors: Christoph Licht, Gianluigi Ardissino, Gema Ariceta, David Cohen, J. Alexander Cole, Christoph Gasteyger, Larry A. Greenbaum, Sally Johnson, Masayo Ogawa, Franz Schaefer, Johan Vande Walle and Véronique Frémeaux-Bacchi
    Citation: BMC Nephrology 2015 16:207
  26. Acute kidney injury is frequently observed at the intensive care unit, after surgery, and after toxic drug administration. A rise in serum creatinine and a fall in urine output are consequences of much earlier...

    Authors: Sahra Pajenda, Aysegül Ilhan-Mutlu, Matthias Preusser, Sebastian Roka, Wilfred Druml and Ludwig Wagner
    Citation: BMC Nephrology 2015 16:206
  27. Removal of phosphate by peritoneal dialysis is insufficient to maintain normal serum phosphate levels such that most patients must take phosphate binders with their meals. However, phosphate ‘counting’ is comp...

    Authors: Simon Leung, Brendan McCormick, Jessica Wagner, Mohan Biyani, Susan Lavoie, Rameez Imtiaz and Deborah Zimmerman
    Citation: BMC Nephrology 2015 16:205
  28. Maintaining tight glycemic control is important for prevention of diabetes-related outcomes in end-stage renal disease patients with diabetes, especially in light of their poor prognosis. This study aimed to d...

    Authors: Jinnie J. Rhee, Victoria Y. Ding, David H. Rehkopf, Cristina M. Arce and Wolfgang C. Winkelmayer
    Citation: BMC Nephrology 2015 16:204
  29. Use of serum creatinine to estimate GFR may lead to underestimation of the association between self-reported frailty and kidney function. Our objectives were to evaluate the association of measured GFR (mGFR) ...

    Authors: Cynthia Delgado, Barbara A. Grimes, David V. Glidden, Michael Shlipak, Mark J. Sarnak and Kirsten L. Johansen
    Citation: BMC Nephrology 2015 16:203
  30. Acceptance of disability (AOD) is a useful construct that assesses the ability of a patient to psychologically cope with chronic diseases, but its effect on long-term outcomes of patients with chronic kidney d...

    Authors: Hsin-Hung Chiang, Hanoch Livneh, How-Ran Guo, Mei-Ling Yen and Tzung-Yi Tsai
    Citation: BMC Nephrology 2015 16:202
  31. Rituximab is widely used in kidney transplantation. However, it is not clear whether the conventional doses of maintenance immunosuppressant in rituximab-treated kidney transplantation (KT) are appropriate. In...

    Authors: Chung Hee Baek, Hyosang Kim, Hoon Yu, Eunhye Shin, Hyungjin Cho, Won Seok Yang, Duck Jong Han and Su-Kil Park
    Citation: BMC Nephrology 2015 16:201
  32. Idiopathic membranous nephropathy (IMN) is a major cause of nephrotic syndrome among adults. Considering the natural course of IMN, when to treat and with which immunosuppressive treatment need to be carefully...

    Authors: Shanshan Liu, Xiayu Li, Heng Li, Qian Liang, Jun Chen and Jianghua Chen
    Citation: BMC Nephrology 2015 16:200
  33. The database of a major regional health insurer was employed to identify the number and frequency of covered patients with chronic kidney disease (CKD). We then examined the characteristics of their care as de...

    Authors: Pradeep Arora, Peter L. Elkin, Joseph Eberle, J. James Bono, Laura Argauer, Brian M. Murray, Raghu Ram and Rocco C. Venuto
    Citation: BMC Nephrology 2015 16:199
  34. Our hypothesis was that both the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) equations would underestimate directly measured GFR (mGFR) to a sim...

    Authors: Richard J. MacIsaac, Elif I. Ekinci, Erosha Premaratne, Zhong X. Lu, Jas-mine Seah, Yue Li, Ray Boston, Glenn M. Ward and George Jerums
    Citation: BMC Nephrology 2015 16:198
  35. Accurate measurement of renal function in cirrhotic patients is still challenging. To find the best test for the determination of the true glomerular filtration rate (GFR) in cirrhotic patients this study pros...

    Authors: Elisabeth Krones, Peter Fickert, Sabine Zitta, Stefan Neunherz, Katharina Artinger, Gilbert Reibnegger, Franziska Durchschein, Doris Wagner, Tatjana Stojakovic, Vanessa Stadlbauer, Günter Fauler, Rudolf Stauber, Gernot Zollner, Daniela Kniepeiss and Alexander R. Rosenkranz
    Citation: BMC Nephrology 2015 16:196
  36. HIV infection is associated with increased risk of renal dysfunction, including tubular dysfunction (TD) related to antiretroviral therapy (ART). Tenofovir disoproxil fumarate (TDF) is becoming available for A...

    Authors: David R. Chadwick, Fred S. Sarfo, Elaine S. M. Kirk, Dorcas Owusu, George Bedu-Addo, Victoria Parris, Ann Lorraine Owusu and Richard Phillips
    Citation: BMC Nephrology 2015 16:195
  37. Hyperphosphataemia is linked to cardiovascular disease and mortality in chronic kidney disease (CKD). Outcome in CKD is also affected by socioeconomic status. The objective of this study was to assess the asso...

    Authors: Marit D. Solbu, Peter C. Thomson, Sarah Macpherson, Mark D. Findlay, Kathryn K Stevens, Rajan K. Patel, Sandosh Padmanabhan, Alan G Jardine and Patrick B. Mark
    Citation: BMC Nephrology 2015 16:194
  38. Multimorbidity is a growing concern for healthcare systems, with many countries experiencing demographic transition to older population profiles. Chronic kidney disease (CKD) is common but often considered in ...

    Authors: Simon D. S. Fraser, Paul J. Roderick, Carl R. May, Natasha McIntyre, Christopher McIntyre, Richard J. Fluck, Adam Shardlow and Maarten W. Taal
    Citation: BMC Nephrology 2015 16:193

    The Correction to this article has been published in BMC Nephrology 2020 21:543

  39. End-stage renal disease patients are characterized by low levels of physical activity, especially during leisure time. However, the recognition of variables associated with patterns of physical activity in thi...

    Authors: Clara S. C. Rosa, Denise R. Bueno, Giovana D. Souza, Luís A. Gobbo, Ismael F. Freitas Jr, Giorgos K. Sakkas and Henrique L. Monteiro
    Citation: BMC Nephrology 2015 16:192
  40. In the US, African Americans (AAs) are four times more likely to develop end stage renal disease (ESRD) but half as likely to receive a kidney transplant as whites. Patient interest in kidney transplantation i...

    Authors: Titilayo O. Ilori, Nosayaba Enofe, Anju Oommen, Oluwaseun Odewole, Akinlolu Ojo, Laura Plantinga, Stephen Pastan, Justin B. Echouffo-Tcheugui and William McClellan
    Citation: BMC Nephrology 2015 16:191
  41. Glomerular diseases are potentially fatal, requiring aggressive interventions and close monitoring. Urine is a readily-accessible body fluid enriched in molecular signatures from the kidney and therefore parti...

    Authors: Marie C. Hogan, John C. Lieske, Chrysta C. Lienczewski, Lisa L. Nesbitt, Larysa T. Wickman, Christina M. Heyer, Peter C. Harris, Christopher J. Ward, Jamie L. Sundsbak, Luca Manganelli, Wenjun Ju, Jeffrey B. Kopp, Peter J. Nelson, Sharon G. Adler, Heather N. Reich, Lawrence B. Holzmann…
    Citation: BMC Nephrology 2015 16:190
  42. Medical decision-making is critical to patient survival and well-being. Patients with end stage renal disease (ESRD) are faced with incrementally complex decision-making throughout their treatment journey. The...

    Authors: Anuradha Jayanti, Markus Neuvonen, Alison Wearden, Julie Morris, Philip Foden, Paul Brenchley and Sandip Mitra
    Citation: BMC Nephrology 2015 16:189
  43. Despite limitations of routine methods, Clinical Practice Guidelines support the assessment of bone mineral density (BMD) and vascular calcification in renal transplant recipients. Changes in fat mass also occ...

    Authors: Sinead Kinsella, Kevin Murphy, Micheal Breen, Siobhan O’Neill, Patrick McLaughlin, Joe Coyle, Conor Bogue, Fiona O’Neill, Niamh Moore, AnneMarie McGarrigle, Michael G. Molloy, Michael M. Maher and Joseph A. Eustace
    Citation: BMC Nephrology 2015 16:188
  44. Primary biliary cirrhosis (PBC) is an immune-mediated chronic cholestatic liver disease, characterized by increased concentrations of serum IgM and the presence of circulating anti-mitochondrial antibodies. Al...

    Authors: Shintaro Yamaguchi, Tatsuya Maruyama, Shu Wakino, Hirobumi Tokuyama, Akinori Hashiguchi, Shinichiro Tada, Koichiro Homma, Toshiaki Monkawa, James Thomas, Kazutoshi Miyashita, Isao Kurihara, Tadashi Yoshida, Konosuke Konishi, Koichi Hayashi, Matsuhiko Hayashi and Hiroshi Itoh
    Citation: BMC Nephrology 2015 16:187
  45. Patients with chronic kidney disease tend to have impaired functional status, and this can increase the risk of morbidity and mortality. However, no previous studies have rigorously evaluated the relationship ...

    Authors: Chia-Ter Chao, Hung-Bin Tsai, Chia-Yi Wu, Nin-Chieh Hsu, Yu-Feng Lin, Jin-Shing Chen and Kuan-Yu Hung
    Citation: BMC Nephrology 2015 16:186
  46. Anti-glomerular basement membrane (GBM) antibody disease is a rare autoimmune disorder characterized by rapidly progressive glomerulonephritis caused by autoantibodies against the α3-chain of type IV collagen ...

    Authors: China Nagano, Yoshimitu Goto, Katuaki Kasahara and Yoshiyuki Kuroyanagi
    Citation: BMC Nephrology 2015 16:185
  47. A representative cross-sectional study showed that chronic itch (lasting for a minimum of 6 weeks) affects 25.2 % (point prevalence) of hemodialysis (HD) patients. Pathophysiology and etiology of chronic itch ...

    Authors: Elke Weisshaar, Melanie Weiss, Jutta Passlick-Deetjen, Ulrich Tschulena, Klaudia Maleki and Thomas Mettang
    Citation: BMC Nephrology 2015 16:184

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