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  1. Canada’s pandemic H1N1 influenza A (pH1N1) outbreak led to a high burden of critical illness. Our objective was to describe the incidence of AKI (acute kidney injury) in these patients and risk factors for AKI...

    Authors: Sean M Bagshaw, Manish M Sood, Jennifer Long, Robert A Fowler and Neill KJ Adhikari
    Citation: BMC Nephrology 2013 14:123
  2. Cardiovascular morbidity and mortality remains excessive in patients with chronic kidney disease. The association of vascular changes with regulators of extraosseous calcification in this patient population is...

    Authors: Panagiotis Pateinakis, Aikaterini Papagianni, Stella Douma, Georgios Efstratiadis and Dimitrios Memmos
    Citation: BMC Nephrology 2013 14:122
  3. The Canadian Study of Prediction of Death, Dialysis and Interim Cardiovascular Events (CanPREDDICT) is a large, prospective, pan-Canadian, cohort study designed to improve our understanding of determinants of ...

    Authors: Adeera Levin, Claudio Rigatto, Barrett Brendan, François Madore, Norman Muirhead, Daniel Holmes, Catherine M Clase, Mila Tang and Ognjenka Djurdjev
    Citation: BMC Nephrology 2013 14:121
  4. KDIGO (Kidney Disease: Improving Global Outcomes) guidelines recommend that a lateral abdominal radiograph should be performed to assess vascular calcification (VC) in dialysis patients. However, abdominal aor...

    Authors: Daqing Hong, Shukun Wu, Lei Pu, Fang Wang, Junru Wang, Zhengtong Wang, Hui Gao, Yue Zhang, Fei Deng, Guisen Li, Qiang He and Li Wang
    Citation: BMC Nephrology 2013 14:120
  5. Patients admitted to the emergency room with renal impairment and undergoing a contrast computed tomography (CT) are at high risk of developing contrast nephropathy as emergency precludes sufficient hydration ...

    Authors: Pierre-Alexandre Poletti, Alexandra Platon, Sophie De Seigneux, Elise Dupuis-Lozeron, François Sarasin, Christoph D Becker, Thomas Perneger, Patrick Saudan and Pierre-Yves Martin
    Citation: BMC Nephrology 2013 14:119
  6. Microalbuminuria is an early marker of chronic kidney disease (CKD). Previous studies have shown that either metabolic syndrome (MetS) or chronic inflammation is related to renal impairment. The aim of this st...

    Authors: Liping Jiang, Wen Huang, Yuanbo Liang, Fenghua Wang, Xinrong Duan, Xiaohui Yang, Jiangping Wen and Ningli Wang
    Citation: BMC Nephrology 2013 14:118
  7. The effect of impaired kidney function on B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) is vague. This study was performed to examine the effect of kidney dysfunction on the afore-mentione...

    Authors: Lena Jafri, Waqar Kashif, Javed Tai, Imran Siddiqui, Iqbal Azam, Hira Shahzad and Farooq Ghani
    Citation: BMC Nephrology 2013 14:117
  8. In vivo models of uremia are important tools to study numerous aspects of acute and chronic kidney disease. Mouse models are pivotal because most genetically engineered animal models are mice, which allow dissec...

    Authors: Ting Jia, Hannes Olauson, Karolina Lindberg, Risul Amin, Karin Edvardsson, Bengt Lindholm, Göran Andersson, Annika Wernerson, Yves Sabbagh, Susan Schiavi and Tobias E Larsson
    Citation: BMC Nephrology 2013 14:116
  9. Little is known about the targets and expectations of practicing nephrologists with regard to timing of preemptive AV access surgery and how these relate to actual observed practice patterns in clinical care.

    Authors: Nisha Bansal, Chenyin He, Daniel P Murphy, Kirsten L Johansen and Chi-yuan Hsu
    Citation: BMC Nephrology 2013 14:115
  10. There is a rising incidence of chronic kidney disease that is likely to pose major problems for both healthcare and the economy in future years. In India, it has been recently estimated that the age-adjusted i...

    Authors: Ajay K Singh, Youssef MK Farag, Bharati V Mittal, Kuyilan Karai Subramanian, Sai Ram Keithi Reddy, Vidya N Acharya, Alan F Almeida, Anil Channakeshavamurthy, H Sudarshan Ballal, Gaccione P, Rajan Issacs, Sanjiv Jasuja, Ashok L Kirpalani, Vijay Kher, Gopesh K Modi, Georgy Nainan…
    Citation: BMC Nephrology 2013 14:114
  11. Despite a confirmed association between restless legs syndrome (RLS) and end-stage renal disease (ESRD), there is no study on patients presenting with nephrotic syndrome (NS). To investigate the frequency of R...

    Authors: Alexandre Braga Libório, João Paulo Lima Santos, Natália Feitosa Arraes Minete, Cecília Alencar de Diógenes, Luiza de Andrade Braga Farias and Veralice Meireles Sales de Bruin
    Citation: BMC Nephrology 2013 14:113
  12. Elevated serum level of fibroblast growth factor-23 (FGF23) is associated with adverse outcomes in dialyzed patients.

    Authors: Hyo Jin Kim, Hyunsuk Kim, Nara Shin, Ki Young Na, Yong Lim Kim, Daejung Kim, Jae Hyun Chang, Young Rim Song, Young-Hwan Hwang, Yon Su Kim, Curie Ahn, Joongyub Lee and Kook-Hwan Oh
    Citation: BMC Nephrology 2013 14:112
  13. Bacterial infections account for most peritoneal dialysis (PD)-associated peritonitis episodes. However, anaerobic PD peritonitis is extremely rare and intuitively associated with intra-abdominal lesions. In t...

    Authors: Chia-Ter Chao, Szu-Ying Lee, Wei-Shun Yang, Huei-Wen Chen, Cheng-Chung Fang, Chung-Jen Yen, Chih-Kang Chiang, Kuan-Yu Hung and Jenq-Wen Huang
    Citation: BMC Nephrology 2013 14:111
  14. Modelling competing risks is an essential issue in Nephrology Research. In peritoneal dialysis studies, sometimes inappropriate methods (i.e. Kaplan-Meier method) have been used to estimate probabilities for a...

    Authors: Laetitia Teixeira, Anabela Rodrigues, Maria J Carvalho, António Cabrita and Denisa Mendonça
    Citation: BMC Nephrology 2013 14:110
  15. Transplant recipients are expected to adhere to a lifelong immunosuppressant therapeutic regimen. However, nonadherence to treatment is an underestimated problem for which no properly validated measurement too...

    Authors: Elisa de Oliveira Marsicano, Neimar da Silva Fernandes, Fernando Colugnati, Fabiane Rossi dos Santos Grincenkov, Natalia Maria da Silva Fernandes, Sabina De Geest and Helady Sanders-Pinheiro
    Citation: BMC Nephrology 2013 14:108
  16. Chronic kidney disease (CKD) is associated with worse outcomes among patients with acute coronary syndrome (ACS). Less is known about the impact of CKD on longitudinal outcomes among clopidogrel treated patien...

    Authors: Michael J Fischer, P Michael Ho, Kelly McDermott, Elliott Lowy and Chirag R Parikh
    Citation: BMC Nephrology 2013 14:107
  17. Reflex anuria is an uncommon cause for acute renal failure, which occurs almost always after manipulation or irritation to kidneys, ureter, bladder or other pelvic organs.

    Authors: Vijayabala Jeevagan, Mitrakrishnan Navinan, Arunie Munasinghe, Abdul Nazar, Anura Wijewardena and Godwin Constantine
    Citation: BMC Nephrology 2013 14:106
  18. Bilirubin (BIL) has been recognized as an endogenous antioxidant that shows a protective effect for cardiorenal diseases. We investigated whether administration of BIL had a protective effect on cyclosporine (...

    Authors: Se Won Oh, Eun Seong Lee, Sejoong Kim, Ki Young Na, Dong Wan Chae, Suhnggwon Kim and Ho Jun Chin
    Citation: BMC Nephrology 2013 14:105
  19. Steroid resistant nephrotic syndrome is a severe hereditary disease often caused by mutations in the NPHS2 gene. This gene encodes the lipid binding protein podocin which localizes to the slit diaphragm of podocy...

    Authors: Linus A Völker, Eva-Maria Schurek, Markus M Rinschen, Judit Tax, Barbara A Schutte, Tobias Lamkemeyer, Denise Ungrue, Bernhard Schermer, Thomas Benzing and Martin Höhne
    Citation: BMC Nephrology 2013 14:102
  20. Group A streptococcus (GAS) is an etiological agent for the immune mediated sequela post streptococcal glomerulonephritis (PSGN). In some populations PSGN is recognized as a risk factor for chronic kidney dise...

    Authors: Mohan Ganesh Karmarkar, Gouri Pandharinath Hule, Niwrutti Khandu Hase, Preeti Rajeev Mehta, Scott Robert Walter and Kadaba Srinivasa Sriprakash
    Citation: BMC Nephrology 2013 14:101
  21. Recent trends in parathyroidectomy rates are not known. Our objective was to investigate the trend in parathyroidectomy rates between 2001 and 2010, and to evaluate if the availability and reimbursement of cin...

    Authors: Jean-Philippe Lafrance, Héloïse Cardinal, Martine Leblanc, François Madore, Vincent Pichette, Louise Roy and Jacques Le Lorier
    Citation: BMC Nephrology 2013 14:100
  22. Current data describing the epidemiology of acute kidney injury (AKI) following repair of ruptured abdominal aortic aneurysm (rAAA) are limited and long-term outcomes are largely unknown. Our objectives were t...

    Authors: Ilana Kopolovic, Kim Simmonds, Shelley Duggan, Mark Ewanchuk, Daniel E Stollery and Sean M Bagshaw
    Citation: BMC Nephrology 2013 14:99
  23. The inhibition of dipeptidyl peptidase (DPP) IV shows protective effects on tissue injury of the heart, lung, and kidney. Forkhead box O (FoxO) transcriptional factors regulate cellular differentiation, growth...

    Authors: Kwon Wook Joo, Sejoong Kim, Shin-young Ahn, Ho Jun Chin, Dong-Wan Chae, Jeonghwan Lee, Jin Suk Han and Ki Young Na
    Citation: BMC Nephrology 2013 14:98
  24. Impaired kidney function is an established predictor of mortality after acute nonvariceal upper gastrointestinal bleeding (ANVUGIB); however, which factors are associated with mortality after ANVUGIB among pat...

    Authors: Ju-Yeh Yang, Tsung-Chun Lee, Maria E Montez-Rath, Glenn M Chertow and Wolfgang C Winkelmayer
    Citation: BMC Nephrology 2013 14:97
  25. It has been shown that nanomaterials (NMs) are able to translocate to secondary tissues one of the important being the kidneys. Oxidative stress has been implicated as a possible mechanism for NM toxicity, hen...

    Authors: Ali Kermanizadeh, Sandra Vranic, Sonja Boland, Kevin Moreau, Armelle Baeza-Squiban, Birgit K Gaiser, Livia A Andrzejczuk and Vicki Stone
    Citation: BMC Nephrology 2013 14:96
  26. Chronic kidney disease (CKD) affects up to 16% of the adult population and is associated with significant morbidity and mortality. People at highest risk from progressive CKD are defined by a sustained decline...

    Authors: Stephanie Stringer, Praveen Sharma, Mary Dutton, Mark Jesky, Khai Ng, Okdeep Kaur, Iain Chapple, Thomas Dietrich, Charles Ferro and Paul Cockwell
    Citation: BMC Nephrology 2013 14:95
  27. Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder that is characterized by the development of cysts in the kidneys and other organs. Urinary protein excretion is usually less than 1...

    Authors: Keiichi Sumida, Yoshifumi Ubara, Junichi Hoshino, Noriko Hayami, Tatsuya Suwabe, Rikako Hiramatsu, Eiko Hasegawa, Masayuki Yamanouchi, Naoki Sawa, Kenmei Takaichi and Kenichi Ohashi
    Citation: BMC Nephrology 2013 14:94
  28. Nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) is a well defined risk factor for subsequent bacteremia and death in various groups of patients, but its impact on outcome in patients re...

    Authors: Holger Schmid, Andre Romanos, Helmut Schiffl and Stephan R Lederer
    Citation: BMC Nephrology 2013 14:93
  29. Metabolic complications are associated with clinical outcomes in patients with chronic kidney disease (CKD). These outcomes differ among patients according to the different stages of disease. The prevalence an...

    Authors: I-Wen Wu, Kuang-Hung Hsu, Chin-Chan Lee, Chiao-Yin Sun, Heng-Jung Hsu, Ming-Jui Hung and Mai-Szu Wu
    Citation: BMC Nephrology 2013 14:92
  30. We describe a case of a fever of unknown etiology that was caused by a caseating tubercle granuloma which produced erythropoietin. To our knowledge, this is the first report of an erythropoietin- producing gra...

    Authors: Minoru Satoh, Hiroshi Ueta, Takehiko Tokura, Tamaki Sasaki and Naoki Kashihara
    Citation: BMC Nephrology 2013 14:91
  31. People with end-stage kidney disease treated with dialysis experience high rates of premature death that are at least 30-fold that of the general population, and have markedly impaired quality of life. Despite...

    Authors: Giovanni FM Strippoli, Suetonia C Palmer, Marinella Ruospo, Patrizia Natale, Valeria Saglimbene, Jonathan C Craig, Fabio Pellegrini, Massimo Petruzzi, Michele De Benedittis, Pauline Ford, David W Johnson, Eduardo Celia, Ruben Gelfman, Miguel R Leal, Marietta Torok, Paul Stroumza…
    Citation: BMC Nephrology 2013 14:90
  32. There is ongoing controversy concerning optimum anticoagulation and buffering in continuous venovenous haemofiltration (CVVH). Regional anticoagulation with trisodium citrate also acting as a buffer in the rep...

    Authors: Shaikh A Nurmohamed, Borefore P Jallah, Marc G Vervloet, Gul Yldirim, Pieter M ter Wee and AB Johan Groeneveld
    Citation: BMC Nephrology 2013 14:89
  33. Biochemical markers of altered mineral metabolism have been associated with increased mortality in end stage renal disease patients. Several studies have demonstrated non-linear (U-shaped or J-shaped) associat...

    Authors: Jaime L Natoli, Rob Boer, Brian H Nathanson, Ross M Miller, Silvia Chiroli, William G Goodman and Vasily Belozeroff
    Citation: BMC Nephrology 2013 14:88
  34. The prevalence of obese and overweight patients has increased dramatically worldwide. Both are common risk factors for chronic kidney disease (CKD) as indicated by a diminished estimated glomerular filtration ...

    Authors: Kathleen Dittmann, Anke Hannemann, Henri Wallaschofski, Rainer Rettig, Sylvia Stracke, Henry Völzke, Matthias Nauck and Nele Friedrich
    Citation: BMC Nephrology 2013 14:87
  35. Chronic kidney disease (CKD) is an emerging public health problem worldwide. Previous studies have shown an association between blood pressure (BP) and CKD. However, it is not clear if there are ethnic differe...

    Authors: Charumathi Sabanayagam, Boon Wee Teo, E Shyong Tai, Tazeen H Jafar and Tien Yin Wong
    Citation: BMC Nephrology 2013 14:86
  36. Fibroblast growth factor 23 (FGF23) is the earliest marker of disturbed mineral metabolism as renal function decreases. Its serum levels are associated with mortality in dialysis patients, persons with chronic...

    Authors: Per-Anton Westerberg, Åsa Tivesten, Magnus K Karlsson, Dan Mellström, Eric Orwoll, Claes Ohlsson, Tobias E Larsson, Torbjörn Linde and Östen Ljunggren
    Citation: BMC Nephrology 2013 14:85
  37. Renal cell carcinoma (RCC) may involve both kidneys. When bilateral nephrectomy is necessary renal replacement therapy is mandatory. Treating such patients with sequential therapy based on cytokines, antiangio...

    Authors: John Syrios, Georgios Kechagias and Nicolas Tsavaris
    Citation: BMC Nephrology 2013 14:84
  38. Psychosocial factors including depression, anxiety and lower social support are common in patients with chronic kidney disease (CKD). However the influence of these potentially modifiable risk factors on morbi...

    Authors: Charlotte M McKercher, Alison J Venn, Leigh Blizzard, Mark R Nelson, Andrew J Palmer, Michael A Ashby, Jennifer L Scott and Matthew D Jose
    Citation: BMC Nephrology 2013 14:83
  39. IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide, leading to renal failure in 15% to 40% of cases. IgAN is diagnosed by renal biopsy, an invasive method that is not risk-free. We ...

    Authors: Fredzzia Graterol, Maribel Navarro-Muñoz, Meritxell Ibernon, Dolores López, Maria-Isabel Troya, Vanessa Pérez, Josep Bonet and Ramón Romero
    Citation: BMC Nephrology 2013 14:82
  40. Large, population-based administrative healthcare databases can be used to identify patients with chronic kidney disease (CKD) when serum creatinine laboratory results are unavailable. We examined the validity...

    Authors: Jamie L Fleet, Stephanie N Dixon, Salimah Z Shariff, Robert R Quinn, Danielle M Nash, Ziv Harel and Amit X Garg
    Citation: BMC Nephrology 2013 14:81
  41. A marked reduction in serum levels of bioactive insulin-like growth factor-I (IGF-I) has been observed in fasting hemodialysis (HD) patients during a 4-h HD session. The aim of the present study was to investi...

    Authors: Mark Reinhard, Jan Frystyk, Bente Jespersen, Mette Bjerre, Jens S Christiansen, Allan Flyvbjerg and Per Ivarsen
    Citation: BMC Nephrology 2013 14:80
  42. There are only a few risk factors known for primary patency loss in patients with an arteriovenous graft or fistula. Furthermore, a limited number of studies have investigated the association between arteriove...

    Authors: Gürbey Ocak, Joris I Rotmans, Carla Y Vossen, Frits R Rosendaal, Raymond T Krediet, Elisabeth W Boeschoten, Friedo W Dekker and Marion Verduijn
    Citation: BMC Nephrology 2013 14:79
  43. Chronic kidney disease (CKD) is a progressive disease that causes a permanent impairment of renal function and premature mortality. The associated prognosis may result in serious psychological distress to the ...

    Authors: Hsin-Hung Chiang, Hanoch Livneh, Mei-Ling Yen, Tsai-Chung Li and Tzung-Yi Tsai
    Citation: BMC Nephrology 2013 14:78
  44. Chronic kidney disease (CKD) is known to expose the patient to a high risk of death due to cardiovascular and infective causes. In parallel, septic shock is a major challenge for cardiovascular and immune syst...

    Authors: Julien Maizel, Romain Deransy, Benedicte Dehedin, Edouard Secq, Elie Zogheib, Elisabeth Lewandowski, Chritstophe Tribouilloy, Ziad A Massy, Gabriel Choukroun and Michel Slama
    Citation: BMC Nephrology 2013 14:77
  45. Renal replacement therapy may have a favorable effect on diastolic left ventricular function, but it is not clear whether hemodiafiltration is superior to hemodialysis in this field. Nitric oxide (NO) and asym...

    Authors: Árpád Czifra, Alida Páll, Julianna Kulcsár, Kitti Barta, Attila Kertész, György Paragh, István Lőrincz, Zoltán Jenei, Anupam Agarwal, Abolfazl Zarjou, József Balla and Zoltán Szabó
    Citation: BMC Nephrology 2013 14:76
  46. Population-based data on the burden of chronic kidney disease (CKD) in sub-Saharan Africa is still very limited. We assessed the prevalence and determinants of CKD, and evaluated the concordance of commonly ad...

    Authors: Tandi E Matsha, Yandiswa Y Yako, Megan A Rensburg, Mogamat S Hassan, Andre P Kengne and Rajiv T Erasmus
    Citation: BMC Nephrology 2013 14:75

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