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  1. Chronic kidney disease (CKD) is known to expose the patient to a high risk of death due to cardiovascular and infective causes. In parallel, septic shock is a major challenge for cardiovascular and immune syst...

    Authors: Julien Maizel, Romain Deransy, Benedicte Dehedin, Edouard Secq, Elie Zogheib, Elisabeth Lewandowski, Chritstophe Tribouilloy, Ziad A Massy, Gabriel Choukroun and Michel Slama
    Citation: BMC Nephrology 2013 14:77
  2. Population-based data on the burden of chronic kidney disease (CKD) in sub-Saharan Africa is still very limited. We assessed the prevalence and determinants of CKD, and evaluated the concordance of commonly ad...

    Authors: Tandi E Matsha, Yandiswa Y Yako, Megan A Rensburg, Mogamat S Hassan, Andre P Kengne and Rajiv T Erasmus
    Citation: BMC Nephrology 2013 14:75
  3. Myeloperoxidase anti-neutrophil cytoplasmic antibody-associated glomerulonephritis (MPO-ANCA-GN) and concurrent membranous nephropathy (MN) are very rare combination. Their causal relationship has been suggest...

    Authors: Michiko Shimada, Takeshi Fujita, Norio Nakamura, Ikuyo Narita, Yuko Shimaya, Reiichi Murakami, Hideaki Yamabe, Hiroshi Osawa and Ken Okumura
    Citation: BMC Nephrology 2013 14:73
  4. During haemodialysis (HD) treatment, increase of platelet (PLT) activation and induction of procoagulant activity is demonstrated. Although the role of the endothelium and its direct interaction with coagulati...

    Authors: Marianne Schoorl, Margreet Schoorl, Menso J Nubé and Piet CM Bartels
    Citation: BMC Nephrology 2013 14:72
  5. The Chimney graft (CG) procedure is one of the novel modification techniques of the endovascular aneurysm repair (EVAR) surgery to treat suprarenal and juxtarenal abdominal aortic aneurysms. Other indications ...

    Authors: Amir Gal-Oz, Yehuda G Wolf, Galia Rosen, Haggai Sharon, Idit F Schwartz and Gil Chernin
    Citation: BMC Nephrology 2013 14:71
  6. Hepcidin is a central regulator of iron metabolism. Serum hepcidin levels are increased in patients with renal insufficiency, which may contribute to anemia. Urine hepcidin was found to be increased in some pa...

    Authors: Hilde PE Peters, Coby MM Laarakkers, Peter Pickkers, Rosalinde Masereeuw, Otto C Boerman, Annemarie Eek, Elisabeth AM Cornelissen, Dorine W Swinkels and Jack FM Wetzels
    Citation: BMC Nephrology 2013 14:70
  7. The epidemic of diabetic nephropathy (DN) has been paralleled by rapid increases in both obesity and diabetes in China. The aim of this study was to investigate the natural history of DN and the association of...

    Authors: Hui-Mei Chen, Wen-Wen Shen, Yong-Chun Ge, Yi-De Zhang, Hong-Lang Xie and Zhi-Hong Liu
    Citation: BMC Nephrology 2013 14:69
  8. Left ventricular (LV) dyssynchrony is associated with increased risk of all-cause mortality in patients with end-stage renal disease. Our aim was to determine the associations of LV dynamic dyssynchrony with p...

    Authors: Ching-Hui Huang, Chia-Chu Chang, Tzu-Lan Chang and Yu-Jun Chang
    Citation: BMC Nephrology 2013 14:68
  9. Resistance to ESAs (erythropoietin stimulating agents) is highly prevalent in hemodialysis patients with diabetes and associated with an increased mortality. The aim of this study was to identify predictors fo...

    Authors: Andreas Schneider, Markus P Schneider, Hubert Scharnagl, Alan G Jardine, Christoph Wanner and Christiane Drechsler
    Citation: BMC Nephrology 2013 14:67
  10. Pulmonary renal syndrome (PRS), denoting the presence of diffuse alveolar hemorrhage and glomerulonephritis as manifestations of systemic autoimmune disease, is very rare in childhood. The coexistence of circu...

    Authors: Radovan Bogdanović, Predrag Minić, Jasmina Marković-Lipkovski, Nataša Stajić, Nataša Savić and Milan Rodić
    Citation: BMC Nephrology 2013 14:66
  11. Steroid-sensitive idiopathic nephrotic syndrome (SSINS) is most often encountered in sporadic cases of minimal change disease (MCD). Only rare cases of familial forms of MCD have been reported and most of them...

    Authors: Hassib Chehade, Francois Cachat, Eric Girardin, Samuel Rotman, Antonio Jorge Correia, Florence Fellmann and Olivier Bonny
    Citation: BMC Nephrology 2013 14:65
  12. Anemia secondary to iron deficiency is common in patients with non-dialysis dependent chronic kidney disease (ND-CKD) but it is unclear if oral supplementation is as effective as intravenous (IV) supplementati...

    Authors: Shankar P Nagaraju, Adam Cohn, Ayub Akbari, Janet L Davis and Deborah L Zimmerman
    Citation: BMC Nephrology 2013 14:64
  13. Lupus nephritis is considered to be a principal cause of morbidity and mortality in SLE. Few studies focus on the association between anti-C1q antibodies in circulation and renal C1q deposition in human lupus ...

    Authors: Ying Tan, Di Song, Li-hua Wu, Feng Yu and Ming-hui Zhao
    Citation: BMC Nephrology 2013 14:63
  14. Mortality in female patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary angioplasty (pPCI) is higher than in men. We examined gender differences in the prevalence and prognostic...

    Authors: Sofie A Gevaert, Dirk De Bacquer, Patrick Evrard, Marc Renard, Christophe Beauloye, Patrick Coussement, Herbert De Raedt, Peter R Sinnaeve and Marc J Claeys
    Citation: BMC Nephrology 2013 14:62
  15. Branchio-oto-renal (BOR) syndrome is an autosomal dominant disorder characterized by branchial, ear, and renal anomalies. The most common gene mutated in BOR patients is EYA1, the human homolog of the Drosophila ...

    Authors: Maddalena Gigante, Marilena d’Altilia, Eustacchio Montemurno, Sterpeta Diella, Francesca Bruno, Giuseppe S Netti, Elena Ranieri, Giovanni Stallone, Barbara Infante, Giuseppe Grandaliano and Loreto Gesualdo
    Citation: BMC Nephrology 2013 14:60
  16. Autosomal dominant polycystic kidney disease (ADPKD) is the most common form of inherited kidney disease that results in renal failure. ADPKD is a systemic disorder with cysts and connective tissue abnormaliti...

    Authors: Jana Reiterová, Jitka Štekrová, Miroslav Merta, Jaroslav Kotlas, Veronika Elišáková, Petr Lněnička, Marie Korabečná, Milada Kohoutová and Vladimír Tesař
    Citation: BMC Nephrology 2013 14:59
  17. Acute kidney injury (AKI) is an independent risk factor for mortality and is responsible for a significant burden of healthcare expenditure, so accurate measurement of its incidence is important. Administrativ...

    Authors: Laurie A Tomlinson, Alex M Riding, Rupert A Payne, Gary A Abel, Charles R Tomson, Ian B Wilkinson, Martin O Roland and Afzal N Chaudhry
    Citation: BMC Nephrology 2013 14:58
  18. Chronic kidney disease (CKD) is a major issue in public health. Its prevalence has been calculated using estimation of glomerular filtration rate (GFR) by the creatinine-based equations developed in the Modifi...

    Authors: Pierre Delanaye, Etienne Cavalier, Olivier Moranne, Laurence Lutteri, Jean-Marie Krzesinski and Olivier Bruyère
    Citation: BMC Nephrology 2013 14:57
  19. Indoxyl sulfate, a uremic toxin, is accumulated in the serum of chronic kidney disease (CKD) patients, accelerating the progression of CKD. In CKD rat kidney, the expressions of nuclear factor (erythroid-deriv...

    Authors: Dilinaer Bolati, Hidehisa Shimizu, Maimaiti Yisireyili, Fuyuhiko Nishijima and Toshimitsu Niwa
    Citation: BMC Nephrology 2013 14:56
  20. Acute kidney injury (AKI) is a common complication after liver transplantation (LT) and associated with a high mortality. The renal resistive index (RI) is used to assess early renal function impairment in cri...

    Authors: Hai-Ying Kong, Fen Chen, Yong He, Lin-Jiao Wu, Li-Qing Wang, Sheng-Mei Zhu and Shu-Sen Zheng
    Citation: BMC Nephrology 2013 14:55
  21. Glomerular filtration rate (GFR) is the best index of renal function, but age, gender and ethnicity can putatively affect its values. The aim of this study was to establish reference values for GFR in healthy ...

    Authors: Ariana Aguiar Soares, Aline Bodanese Prates, Letícia Schwerz Weinert, Francisco Veríssimo Veronese, Mirela Jobim de Azevedo and Sandra Pinho Silveiro
    Citation: BMC Nephrology 2013 14:54
  22. Lipoprotein glomerulopathy (LPG) is a rare inherited renal disease characterized by intraglomerular lipoprotein within the lumina of severely dilated glomerular capillaries. The common clinical presentation of...

    Authors: Yu Wu, Xiaohan Chen, Yuan Yang, Baohe Wang, Xiaoxia Liu, Ye Tao, Ping Fu and Zhangxue Hu
    Citation: BMC Nephrology 2013 14:53
  23. Proteinuria and dilatation of the urinary tract are both relatively common in pregnancy, the latter with a spectrum of symptoms, from none to severe pain and infection. Proteinuria is a rare occurrence in acut...

    Authors: Giorgina B Piccoli, Rossella Attini, Silvia Parisi, Federica N Vigotti, Germana Daidola, Maria Chiara Deagostini, Martina Ferraresi, Agostino De Pascale, Francesco Porpiglia, Andrea Veltri and Tullia Todros
    Citation: BMC Nephrology 2013 14:52
  24. The Liu Comorbidity Index uses the United States Renal Data System (USRDS) to quantify comorbidity in chronic dialysis patients, capturing baseline comorbidities from days 91 through 270 after dialysis initiat...

    Authors: Sally K Rigler, James B Wetmore, Jonathan D Mahnken, Lei Dong, Edward F Ellerbeck and Theresa I Shireman
    Citation: BMC Nephrology 2013 14:51
  25. Patients on maintenance hemodialysis (HD) have much higher levels of adiponectin (Total-APN). Adiponectin and C1q form a protein complex in human blood, and serum C1q-binding adiponectin (C1q-APN) can be measu...

    Authors: Ken Kishida, Naohiro Kishida, Masaaki Arima, Hideaki Nakatsuji, Hironori Kobayashi, Tohru Funahashi and Iichiro Shimomura
    Citation: BMC Nephrology 2013 14:50
  26. There is concern that not all cases of chronic kidney disease (CKD) are known to general practitioners, leading to an underestimate of its true prevalence. We carried out this study to develop a model to predi...

    Authors: Benjamin Kearns, Hugh Gallagher and Simon de Lusignan
    Citation: BMC Nephrology 2013 14:49
  27. Aim of this study was to evaluate whether the A736V TMPRSS6 polymorphism, a major genetic determinant of iron metabolism in healthy subjects, influences serum levels of hepcidin, the hormone regulating iron me...

    Authors: Serena Pelusi, Domenico Girelli, Raffaela Rametta, Natascia Campostrini, Carlo Alfieri, Michela Traglia, Paola Dongiovanni, Giovanna Como, Daniela Toniolo, Clara Camaschella, Piergiorgio Messa, Silvia Fargion and Luca Valenti
    Citation: BMC Nephrology 2013 14:48
  28. Focal segmental glomerulosclerosis (FSGS) is a frequent cause of end-stage renal disease. Renal transplantation in patients with FSGS is often complicated by disease recurrence, which is associated with poor o...

    Authors: Rutger JH Maas, Jeroen KJ Deegens, Jan AJG van den Brand, Elisabeth AM Cornelissen and Jack FM Wetzels
    Citation: BMC Nephrology 2013 14:47
  29. The objective of this study was to determinate the prevalence of chronic kidney disease (CKD) and the different stages of CKD in patients with type 2 diabetes mellitus (DM2) treated in primary care consults in...

    Authors: Antonio Rodriguez-Poncelas, Josep Garre-Olmo, Josep Franch-Nadal, Javier Diez-Espino, Xavier Mundet-Tuduri, Joan Barrot-De la Puente and Gabriel Coll-de Tuero
    Citation: BMC Nephrology 2013 14:46
  30. Obesity and metabolic syndrome play causative roles in the increasing prevalence of proteinuria in the general population. However, in young adult women the clinical significance of incidentally discovered pro...

    Authors: Jwa-Kyung Kim, Young-Su Ju, Sung Jin Moon, Young Rim Song, Hyung Jik Kim and Sung Gyun Kim
    Citation: BMC Nephrology 2013 14:45
  31. Some hemodialysis patients require large doses of erythropoiesis-stimulating agents (ESAs) to manage anemia. These patients, termed “ESA hyporesponsive,” have been characterized using various definitions. We a...

    Authors: David T Gilbertson, Yi Peng, Thomas J Arneson, Stephan Dunning and Allan J Collins
    Citation: BMC Nephrology 2013 14:44
  32. Acute kidney injury is a common complication of liver transplantation. In this single-centre retrospective observational study, we investigated the impact of acute kidney disease on liver recipient survival.

    Authors: Roberto Camargo Narciso, Leonardo Rolim Ferraz, Sergio Mies, Julio Cesar Martins Monte, Oscar Fernando Pavão dos Santos, Miguel Cendoroglo Neto, Cassio José de Oliveira Rodrigues, Marcelo Costa Batista and Marcelino Souza Durão Junior
    Citation: BMC Nephrology 2013 14:43
  33. Chronic cyclosporine-(CsA)-mediated loss of kidney function is a major clinical problem in organ transplantation. We hypothesized that the mineralocorticoid receptor antagonist eplerenone (EPL) prevents chroni...

    Authors: Finn Thomsen Nielsen, Boye L Jensen, Pernille BL Hansen, Niels Marcussen and Peter Bie
    Citation: BMC Nephrology 2013 14:42
  34. Effective therapeutic strategies are available to prevent adverse outcomes in patients with chronic kidney disease (CKD) but their clinical results are hindered by unplanned implementation. Coordination of car...

    Authors: Nicolas Rognant, Eric Alamartine, Jean Claude Aldigier, Christian Combe, Benoit Vendrely, Patrice Deteix, Pascal Cluzel, Laurent Juillard, François Vrtovsnik, Christelle Maurice, Sophie Fave and Maurice Laville
    Citation: BMC Nephrology 2013 14:41
  35. This short-term study assessed the efficacy and safety of lanthanum carbonate in the treatment of hyperphosphatemia in dialysis patients; here, we report a prespecified subgroup analysis of patients undergoing...

    Authors: Alastair J Hutchison, Maggie Gill, J Brian Copley, Lynne Poole and Rosamund J Wilson
    Citation: BMC Nephrology 2013 14:40
  36. Fibroblast growth factor-23 (FGF-23), a novel marker of bone disease in chronic kidney disease (CKD) has been shown to correlate with vascular calcifications. We aimed to describe the effect of the calcium pho...

    Authors: Abeer Yasin, Daisy Liu, Luan Chau, Joaquín Madrenas and Guido Filler
    Citation: BMC Nephrology 2013 14:39
  37. Renal failure with following continuous renal replacement therapy is a major clinical problem in liver transplant recipients, with reported incidences of 3% to 20%. Little is known about the significance of po...

    Authors: Urs Wenger, Thomas A Neff, Christian E Oberkofler, Manuel Zimmermann, Paul A Stehberger, Marcel Scherrer, Reto A Schuepbach, Silvia R Cottini, Peter Steiger and Markus Béchir
    Citation: BMC Nephrology 2013 14:37
  38. Critical illness polyneuropathy (CIP) and critical illness myopathy (CIM) are complications causing weakness of respiratory and limb muscles in critically ill patients. As an important differential diagnosis o...

    Authors: Hai Li, Li-Min Wu, Xiang-Bo Kong, Yi Hou, Rui Zhao, Hong-Yan Li and Hong-Liang Zhang
    Citation: BMC Nephrology 2013 14:36
  39. Prevention of chronic kidney disease (CKD) is a major public health issue. Although several studies have been performed on the association between alcohol consumption and CKD or renal function, it remains cont...

    Authors: Akatsuki Kokaze, Mamoru Ishikawa, Naomi Matsunaga, Kanae Karita, Masao Yoshida, Naoki Shimada, Tadahiro Ohtsu, Takako Shirasawa, Hirotaka Ochiai, Hiromi Hoshino and Yutaka Takashima
    Citation: BMC Nephrology 2013 14:35
  40. Polycystin-2 (PC2), encoded by the gene that is mutated in autosomal dominant polycystic kidney disease (ADPKD), functions as a calcium (Ca2+) permeable ion channel. Considerable controversy remains regarding the...

    Authors: Ayako Miyakawa, Cristián Ibarra, Seth Malmersjö, Anita Aperia, Peter Wiklund and Per Uhlén
    Citation: BMC Nephrology 2013 14:34
  41. Gremlin, a bone morphogenetic protein antagonist, plays an important role in the pathogenesis of diabetic nephropathy (DN). However, the specific molecular mechanism underlying Gremlin’s involvement in DN has ...

    Authors: Haixia Huang, Haiying Huang, Ying Li, Maodong Liu, Yonghong Shi, Yanqing Chi and Tao Zhang
    Citation: BMC Nephrology 2013 14:33
  42. Acute kidney injury (AKI) is common in hospitalized human immunodeficiency virus (HIV)-infected patients and is associated with hospital mortality. We aimed to evaluate the impact of AKI on long-term mortality...

    Authors: José António Lopes, Maria João Melo, Mário Raimundo, André Fragoso and Francisco Antunes
    Citation: BMC Nephrology 2013 14:32
  43. Contrast-enhanced radiographic examinations carry the risk of contrast-associated acute kidney injury (CA-AKI). While CA-AKI is a well-known complication outside the intensive care unit (ICU) setting, data on ...

    Authors: Christophe Clec’h, Dominique Razafimandimby, Mehdi Laouisset, Frank Chemouni and Yves Cohen
    Citation: BMC Nephrology 2013 14:31
  44. Creatinine based formulae for estimating renal function developed in white populations may be less valid in other ethnic groups. We assessed the performance of various estimating formulae in an Indian population.

    Authors: Phillippa K Bailey, Charles RV Tomson, Sanjay Kinra, Shah Ebrahim, KV Radhakrishna, Hannah Kuper, Dorothea Nitsch and Yoav Ben-Shlomo
    Citation: BMC Nephrology 2013 14:30
  45. Serum phosphorus control is critical for chronic kidney disease (CKD) 5D patients. Currently, clinical profile for an oral phosphorus binder in the mainland Chinese population is not available.

    Authors: Jing Xu, Yi-Xiang Zhang, Xue-Qing Yu, Zhi-Hong Liu, Li-Ning Wang, Jiang-Hua Chen, Ya-Ping Fan, Zhao-Hui Ni, Mei Wang, Fa-Huan Yuan, Guo-Hua Ding, Xiang-Mei Chen, Ai-Ping Zhang and Chang-Lin Mei
    Citation: BMC Nephrology 2013 14:29
  46. The role of small solute clearance on mortalities in patients with CAPD has been controversial. We therefore conducted a study with 3 years' follow up in adult patients who participated in the CAPD-first policy.

    Authors: Phisitt Vejakama, Ammarin Thakkinstian, Atiporn Ingsathit, Prateep Dhanakijcharoen and John Attia
    Citation: BMC Nephrology 2013 14:28
  47. Vascular calcification (VC) and carotid intima media thickness (CIMT) are strongly associated with cardiovascular (CV) disease. We hypothesized that significant VC on plain radiographs is associated with CIMT ...

    Authors: Won Suk An and Young Ki Son
    Citation: BMC Nephrology 2013 14:27

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