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  1. There is concern that not all cases of chronic kidney disease (CKD) are known to general practitioners, leading to an underestimate of its true prevalence. We carried out this study to develop a model to predi...

    Authors: Benjamin Kearns, Hugh Gallagher and Simon de Lusignan
    Citation: BMC Nephrology 2013 14:49
  2. Aim of this study was to evaluate whether the A736V TMPRSS6 polymorphism, a major genetic determinant of iron metabolism in healthy subjects, influences serum levels of hepcidin, the hormone regulating iron me...

    Authors: Serena Pelusi, Domenico Girelli, Raffaela Rametta, Natascia Campostrini, Carlo Alfieri, Michela Traglia, Paola Dongiovanni, Giovanna Como, Daniela Toniolo, Clara Camaschella, Piergiorgio Messa, Silvia Fargion and Luca Valenti
    Citation: BMC Nephrology 2013 14:48
  3. Focal segmental glomerulosclerosis (FSGS) is a frequent cause of end-stage renal disease. Renal transplantation in patients with FSGS is often complicated by disease recurrence, which is associated with poor o...

    Authors: Rutger JH Maas, Jeroen KJ Deegens, Jan AJG van den Brand, Elisabeth AM Cornelissen and Jack FM Wetzels
    Citation: BMC Nephrology 2013 14:47
  4. The objective of this study was to determinate the prevalence of chronic kidney disease (CKD) and the different stages of CKD in patients with type 2 diabetes mellitus (DM2) treated in primary care consults in...

    Authors: Antonio Rodriguez-Poncelas, Josep Garre-Olmo, Josep Franch-Nadal, Javier Diez-Espino, Xavier Mundet-Tuduri, Joan Barrot-De la Puente and Gabriel Coll-de Tuero
    Citation: BMC Nephrology 2013 14:46
  5. Obesity and metabolic syndrome play causative roles in the increasing prevalence of proteinuria in the general population. However, in young adult women the clinical significance of incidentally discovered pro...

    Authors: Jwa-Kyung Kim, Young-Su Ju, Sung Jin Moon, Young Rim Song, Hyung Jik Kim and Sung Gyun Kim
    Citation: BMC Nephrology 2013 14:45
  6. Some hemodialysis patients require large doses of erythropoiesis-stimulating agents (ESAs) to manage anemia. These patients, termed “ESA hyporesponsive,” have been characterized using various definitions. We a...

    Authors: David T Gilbertson, Yi Peng, Thomas J Arneson, Stephan Dunning and Allan J Collins
    Citation: BMC Nephrology 2013 14:44
  7. Acute kidney injury is a common complication of liver transplantation. In this single-centre retrospective observational study, we investigated the impact of acute kidney disease on liver recipient survival.

    Authors: Roberto Camargo Narciso, Leonardo Rolim Ferraz, Sergio Mies, Julio Cesar Martins Monte, Oscar Fernando Pavão dos Santos, Miguel Cendoroglo Neto, Cassio José de Oliveira Rodrigues, Marcelo Costa Batista and Marcelino Souza Durão Junior
    Citation: BMC Nephrology 2013 14:43
  8. Chronic cyclosporine-(CsA)-mediated loss of kidney function is a major clinical problem in organ transplantation. We hypothesized that the mineralocorticoid receptor antagonist eplerenone (EPL) prevents chroni...

    Authors: Finn Thomsen Nielsen, Boye L Jensen, Pernille BL Hansen, Niels Marcussen and Peter Bie
    Citation: BMC Nephrology 2013 14:42
  9. Effective therapeutic strategies are available to prevent adverse outcomes in patients with chronic kidney disease (CKD) but their clinical results are hindered by unplanned implementation. Coordination of car...

    Authors: Nicolas Rognant, Eric Alamartine, Jean Claude Aldigier, Christian Combe, Benoit Vendrely, Patrice Deteix, Pascal Cluzel, Laurent Juillard, François Vrtovsnik, Christelle Maurice, Sophie Fave and Maurice Laville
    Citation: BMC Nephrology 2013 14:41
  10. This short-term study assessed the efficacy and safety of lanthanum carbonate in the treatment of hyperphosphatemia in dialysis patients; here, we report a prespecified subgroup analysis of patients undergoing...

    Authors: Alastair J Hutchison, Maggie Gill, J Brian Copley, Lynne Poole and Rosamund J Wilson
    Citation: BMC Nephrology 2013 14:40
  11. Fibroblast growth factor-23 (FGF-23), a novel marker of bone disease in chronic kidney disease (CKD) has been shown to correlate with vascular calcifications. We aimed to describe the effect of the calcium pho...

    Authors: Abeer Yasin, Daisy Liu, Luan Chau, Joaquín Madrenas and Guido Filler
    Citation: BMC Nephrology 2013 14:39
  12. Renal failure with following continuous renal replacement therapy is a major clinical problem in liver transplant recipients, with reported incidences of 3% to 20%. Little is known about the significance of po...

    Authors: Urs Wenger, Thomas A Neff, Christian E Oberkofler, Manuel Zimmermann, Paul A Stehberger, Marcel Scherrer, Reto A Schuepbach, Silvia R Cottini, Peter Steiger and Markus Béchir
    Citation: BMC Nephrology 2013 14:37
  13. Critical illness polyneuropathy (CIP) and critical illness myopathy (CIM) are complications causing weakness of respiratory and limb muscles in critically ill patients. As an important differential diagnosis o...

    Authors: Hai Li, Li-Min Wu, Xiang-Bo Kong, Yi Hou, Rui Zhao, Hong-Yan Li and Hong-Liang Zhang
    Citation: BMC Nephrology 2013 14:36
  14. Prevention of chronic kidney disease (CKD) is a major public health issue. Although several studies have been performed on the association between alcohol consumption and CKD or renal function, it remains cont...

    Authors: Akatsuki Kokaze, Mamoru Ishikawa, Naomi Matsunaga, Kanae Karita, Masao Yoshida, Naoki Shimada, Tadahiro Ohtsu, Takako Shirasawa, Hirotaka Ochiai, Hiromi Hoshino and Yutaka Takashima
    Citation: BMC Nephrology 2013 14:35
  15. Polycystin-2 (PC2), encoded by the gene that is mutated in autosomal dominant polycystic kidney disease (ADPKD), functions as a calcium (Ca2+) permeable ion channel. Considerable controversy remains regarding the...

    Authors: Ayako Miyakawa, Cristián Ibarra, Seth Malmersjö, Anita Aperia, Peter Wiklund and Per Uhlén
    Citation: BMC Nephrology 2013 14:34
  16. Gremlin, a bone morphogenetic protein antagonist, plays an important role in the pathogenesis of diabetic nephropathy (DN). However, the specific molecular mechanism underlying Gremlin’s involvement in DN has ...

    Authors: Haixia Huang, Haiying Huang, Ying Li, Maodong Liu, Yonghong Shi, Yanqing Chi and Tao Zhang
    Citation: BMC Nephrology 2013 14:33
  17. Acute kidney injury (AKI) is common in hospitalized human immunodeficiency virus (HIV)-infected patients and is associated with hospital mortality. We aimed to evaluate the impact of AKI on long-term mortality...

    Authors: José António Lopes, Maria João Melo, Mário Raimundo, André Fragoso and Francisco Antunes
    Citation: BMC Nephrology 2013 14:32
  18. Contrast-enhanced radiographic examinations carry the risk of contrast-associated acute kidney injury (CA-AKI). While CA-AKI is a well-known complication outside the intensive care unit (ICU) setting, data on ...

    Authors: Christophe Clec’h, Dominique Razafimandimby, Mehdi Laouisset, Frank Chemouni and Yves Cohen
    Citation: BMC Nephrology 2013 14:31
  19. Creatinine based formulae for estimating renal function developed in white populations may be less valid in other ethnic groups. We assessed the performance of various estimating formulae in an Indian population.

    Authors: Phillippa K Bailey, Charles RV Tomson, Sanjay Kinra, Shah Ebrahim, KV Radhakrishna, Hannah Kuper, Dorothea Nitsch and Yoav Ben-Shlomo
    Citation: BMC Nephrology 2013 14:30
  20. Serum phosphorus control is critical for chronic kidney disease (CKD) 5D patients. Currently, clinical profile for an oral phosphorus binder in the mainland Chinese population is not available.

    Authors: Jing Xu, Yi-Xiang Zhang, Xue-Qing Yu, Zhi-Hong Liu, Li-Ning Wang, Jiang-Hua Chen, Ya-Ping Fan, Zhao-Hui Ni, Mei Wang, Fa-Huan Yuan, Guo-Hua Ding, Xiang-Mei Chen, Ai-Ping Zhang and Chang-Lin Mei
    Citation: BMC Nephrology 2013 14:29
  21. The role of small solute clearance on mortalities in patients with CAPD has been controversial. We therefore conducted a study with 3 years' follow up in adult patients who participated in the CAPD-first policy.

    Authors: Phisitt Vejakama, Ammarin Thakkinstian, Atiporn Ingsathit, Prateep Dhanakijcharoen and John Attia
    Citation: BMC Nephrology 2013 14:28
  22. Vascular calcification (VC) and carotid intima media thickness (CIMT) are strongly associated with cardiovascular (CV) disease. We hypothesized that significant VC on plain radiographs is associated with CIMT ...

    Authors: Won Suk An and Young Ki Son
    Citation: BMC Nephrology 2013 14:27
  23. Epicardial fat, quantified in a single multi-slice computed tomography (MSCT) slice, is a reliable estimate of total epicardial fat volume (EFV). We sought to determine risk factors for EFV detected in a singl...

    Authors: Jasmine D Kerr, Rachel M Holden, Alexander R Morton, Robert L Nolan, Wilma M Hopman, Cynthia M Pruss and Jocelyn S Garland
    Citation: BMC Nephrology 2013 14:26
  24. Nephrotic syndrome is one of the most commonly diagnosed kidney diseases in childhood and its progressive forms can lead to chronic kidney disease (CKD) and/or end-stage renal disease (ESRD). There have been f...

    Authors: Neesha Hussain, J Anastasia Zello, Jovanka Vasilevska-Ristovska, Tonny M Banh, Viral P Patel, Pranali Patel, Christopher D Battiston, Diane Hebert, Christoph P B Licht, Tino D Piscione and Rulan S Parekh
    Citation: BMC Nephrology 2013 14:25
  25. Anaemia is a known risk factor for cardiovascular disease and treating anaemia in chronic kidney disease (CKD) may improve outcomes. However, little is known about the scope to improve primary care management ...

    Authors: Olga Dmitrieva, Simon de Lusignan, Iain C Macdougall, Hugh Gallagher, Charles Tomson, Kevin Harris, Terry Desombre and David Goldsmith
    Citation: BMC Nephrology 2013 14:24
  26. Galectin-9 (Gal-9) induces apoptosis in activated T helper 1 (TH1) cells as a ligand for T cell immunoglobulin mucin-3 (Tim-3). Gal-9 also inhibits the G1 phase cell cycle arrest and hypertrophy in db/db mice, th...

    Authors: Yuko Kurose, Jun Wada, Motoko Kanzaki, Sanae Teshigawara, Atsuko Nakatsuka, Kazutoshi Murakami, Kentaro Inoue, Takahiro Terami, Akihiro Katayama, Mayu Watanabe, Chigusa Higuchi, Jun Eguchi, Nobuyuki Miyatake and Hirofumi Makino
    Citation: BMC Nephrology 2013 14:23
  27. Fibroblast growth factor 23 (FGF23) is an important hormone in the regulation of phosphate metabolism. It is unclear whether FGF23 is associated with carotid artery calcification (CAAC) in predialysis patients...

    Authors: Masaru Nakayama, Yoshiki Kaizu, Masaharu Nagata, Yoriko Ura, Hirofumi Ikeda, Sho Shimamoto and Kazuyoshi Kuma
    Citation: BMC Nephrology 2013 14:22
  28. Family members of patients with end stage renal disease were reported to have an increased prevalence of chronic kidney disease (CKD). However, studies differentiated genetic and non-genetic family members are...

    Authors: Xianglei Kong, Li Liu, Li Zuo, Ping Yuan, Zhongxin Li, Wenge Li, Meishun Cai, Xiangmei Chen, Aili Jiang, Gang Long, Jinsheng Xu, Hongli Lin, Shixiang Wang, Wen Huang, Yiping Wang, Yidan Guo…
    Citation: BMC Nephrology 2013 14:19
  29. Recently, acetate-free citrate containing dialysate (A(−)D) was developed. We have already reported about the significant effect of A(−)D on metabolic acidosis, anemia, and malnutrition in maintenance hemodial...

    Authors: Takahiro Kuragano, Minoru Furuta, Mana Yahiro, Aritoshi Kida, Yoshinaga Otaki, Yukiko Hasuike, Akihide Matsumoto and Takeshi Nakanishi
    Citation: BMC Nephrology 2013 14:18
  30. AKI is common following liver transplantation and is associated with significant morbidity and mortality. Biomarkers of AKI have not been well established in this setting but are needed to help guide patient c...

    Authors: Jeffrey C Sirota, Angela Walcher, Sarah Faubel, Alkesh Jani, Kim McFann, Prasad Devarajan, Connie L Davis and Charles L Edelstein
    Citation: BMC Nephrology 2013 14:17
  31. S100A12 protein is an endogenous receptor ligand for advanced glycation end products. In this study, the plasma S100A12 level was assessed as an independent predictor of mortality, and its utility in clinical ...

    Authors: Yayoi Shiotsu, Yasukiyo Mori, Masato Nishimura, Tsuguru Hatta, Naoki Imada, Noboru Maki, Kumiko Iida, Noriyuki Iwamoto, Eiko Matsuoka, Keiichi Tamagaki and Atsushi Kosaki
    Citation: BMC Nephrology 2013 14:16
  32. There are no prior studies that have estimated the risk of upper gastrointestinal bleeding (UGIB) among the dialysis population relative to the general population. The aim of this study was to examine the risk...

    Authors: Chien-Chun Kuo, Hsin-Wei Kuo, I-Ming Lee, Chien-Te Lee and Chun-Yuh Yang
    Citation: BMC Nephrology 2013 14:15
  33. Marked hyperphosphatemia, hyperparathyroidism and 25-hydroxyvitamin D deficiency are associated with mortality in dialysis patients. Such data in chronic kidney disease stage 2–4 population are limited. It has...

    Authors: Kamonwan Chartsrisak, Kotcharat Vipattawat, Montira Assanatham, Arkom Nongnuch, Atiporn Ingsathit, Somnuek Domrongkitchaiporn, Vasant Sumethkul and Sinee Distha-Banchong
    Citation: BMC Nephrology 2013 14:14
  34. Rifampin is one of the most important drugs in first-line therapies for tuberculosis. The renal toxicity of rifampin has been reported sporadically and acute tubulointerstitial nephritis (ATIN) is a frequent h...

    Authors: Hong Ki Min, Eun Oh Kim, Sang Ju Lee, Yoon Kyung Chang, Kwang Sun Suh, Chul Woo Yang, Suk Young Kim and Hyeon Seok Hwang
    Citation: BMC Nephrology 2013 14:13
  35. Previous studies have demonstrated Aboriginals are less likely to receive a renal transplant in comparison to Caucasians however whether this applies to the entire population or specific subsets remains unclea...

    Authors: Steven Promislow, Brenda Hemmelgarn, Claudio Rigatto, Navdeep Tangri, Paul Komenda, Leroy Storsley, Karen Yeates, Julie Mojica and Manish M Sood
    Citation: BMC Nephrology 2013 14:11
  36. Process of accelerated atherosclerosis specific for uremia increases cardiovascular risk in patients with chronic kidney disease (CKD) and may be influenced by the different structure of arteries. The study as...

    Authors: Przemysław Pencak, Beata Czerwieńska, Rafał Ficek, Katarzyna Wyskida, Agata Kujawa-Szewieczek, Magdalena Olszanecka-Glinianowicz, Andrzej Więcek and Jerzy Chudek
    Citation: BMC Nephrology 2013 14:10
  37. Little is known regarding the types of information African American and non-African American patients with chronic kidney disease (CKD) and their families need to inform renal replacement therapy (RRT) decisions.

    Authors: Nicole DePasquale, Patti L Ephraim, Jessica Ameling, Lapricia Lewis-Boyér, Deidra C Crews, Raquel C Greer, Hamid Rabb, Neil R Powe, Bernard G Jaar, Luis Gimenez, Priscilla Auguste, Mollie Jenckes and L Ebony Boulware
    Citation: BMC Nephrology 2013 14:9
  38. Diabetes is an important reason for end-stage renal failure and diabetic foot wounds worsen the life qualities of these patients. Protein and amino acid support accelerates the wound healing. The purpose of th...

    Authors: Savas Sipahi, Ozkan Gungor, Mehmet Gunduz, Mehmet Cilci, Mustafaa Cahit Demirci and Ali Tamer
    Citation: BMC Nephrology 2013 14:8
  39. Pain is a negative factor in the recovery process of postoperative patients, causing pulmonary alterations and complications and affecting functional capacity. Thus, it is plausible to introduce transcutaneous...

    Authors: Thiago Tafarel Galli, Luciana Dias Chiavegato, Nathália Risso Santiago and Richard Eloin Liebano
    Citation: BMC Nephrology 2013 14:7
  40. IgA nephropathy (IgAN) is the most common glomerulonephritis, which may also coexist with other diseases. We present two patients with an unusual coincidence of IgAN and Fabry disease (FD).

    Authors: Dita Maixnerová, Vladimír Tesař, Romana Ryšavá, Jana Reiterová, Helena Poupětová, Lenka Dvořáková, Lubor Goláň, Michaela Neprašová, Jana Kidorová, Miroslav Merta and Eva Honsová
    Citation: BMC Nephrology 2013 14:6
  41. Chronic kidney disease (CKD) poses a financial burden on patients and their households. This descriptive study measures the prevalence of economic hardship and out-of-pocket costs in an Australian CKD population.

    Authors: Beverley M Essue, Germaine Wong, Jeremy Chapman, Qiang Li and Stephen Jan
    Citation: BMC Nephrology 2013 14:5
  42. Metabolic acidosis leads to chronic kidney disease (CKD) progression. The guidelines recommend a lower limit of serum bicarbonate level, but no upper limit. For serum bicarbonate level to be clinically useful ...

    Authors: Eiichiro Kanda, Masumi Ai, Masayuki Yoshida, Renjiro Kuriyama and Tatsuo Shiigai
    Citation: BMC Nephrology 2013 14:4
  43. Hemolytic and uremic syndrome (HUS) diagnosis involves association of non immune hemolytic anemia, thrombocytopenia, and renal failure. HUS without thrombocytopenia has been observed, we call it partial HUS. I...

    Authors: Marion Sallée, Khalil Ismail, Fadi Fakhouri, Henri Vacher-Coponat, Julie Moussi-Francés, Véronique Frémaux-Bacchi and Stéphane Burtey
    Citation: BMC Nephrology 2013 14:3
  44. Anemia is a common condition in CKD that has been identified as a cardiovascular (CV) risk factor in end-stage renal disease, constituting a predictor of low survival. The aim of this study was to define the o...

    Authors: José Portolés, Jose Luis Gorriz, Esther Rubio, Fernando de Alvaro, Florencio García, Vicente Alvarez-Chivas, Pedro Aranda and Alberto Martinez-Castelao
    Citation: BMC Nephrology 2013 14:2
  45. Urinary tract infection (UTI) occurs in 30%-50% of individuals with autosomal dominant polycystic kidney disease (ADPKD). However, the clinical relevance of asymptomatic pyuria in ADPKD patients remains unknown.

    Authors: Jin Ho Hwang, Hayne Cho Park, Jong Cheol Jeong, Seon ha Baek, Mi Yeun Han, Kitae Bang, Jeong Yeon Cho, Suk Hee Yu, Jaeseok Yang, Kook-Hwan Oh, Young-Hwan Hwang and Curie Ahn
    Citation: BMC Nephrology 2013 14:1
  46. Subacute bacterial endocarditis (SBE) occasionally exhibits positive cytoplasmic anti-neutrophil cytoplasmic antibody (c-ANCA) of the anti-proteinase-3 (PR-3) type. Clinically, it mimics ANCA-associated vascul...

    Authors: Hui Peng, Wen-fang Chen, Chao Wu, Yan-ru Chen, Bo Peng, Sujay Dutta Paudel and Tan-qi Lou
    Citation: BMC Nephrology 2012 13:174

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