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  1. The number of patients with advanced chronic kidney disease opting for conservative management rather than dialysis is unknown but likely to be growing as increasingly frail patients with advanced renal diseas...

    Authors: Helen Rose Noble, Ashley Agus, Kevin Brazil, Aine Burns, Nicola A Goodfellow, Mary Guiney, Fiona McCourt, Cliona McDowell, Charles Normand, Paul Roderick, Colin Thompson, A. P. Maxwell and M. M. Yaqoob
    Citation: BMC Nephrology 2015 16:104
    Content type: Study protocol Published on:

  2. Sri Lankan Agricultural Nephropathy (SAN), a new form of chronic kidney disease among paddy farmers was first reported in 1994. It has now become the most debilitating public health issue in the dry zone of Sr...

    Authors: Channa Jayasumana, Sarath Gunatilake and Sisira Siribaddana
    Citation: BMC Nephrology 2015 16:103
    Content type: Research article Published on:

  3. Rates of medication non-adherence in dialysis patients are high, and improving adherence is likely to improve outcomes. Few data are available regarding factors associated with medication adherence in dialysis...

    Authors: Trudi Aspden, Martin J Wolley, Tian M Ma, Edwin Rajah, Samantha Curd, Dharni Kumar, Sophia Lee, Krenare Pireva, Olita Taule’alo, Porsche Tiavale, Angela L Kam, Jun S Suh, Julia Kennedy and Mark R Marshall
    Citation: BMC Nephrology 2015 16:102
    Content type: Study protocol Published on:

  6. Poor appetite could be indicative of protein energy wasting (PEW) and experts recommend assessing appetite in dialysis patients. Our study aims to determine the relationship between PEW and appetite in haemodi...

    Authors: Sharmela Sahathevan, Chee Hee Se, See Hoe Ng, Karuthan Chinna, Gilcharan Singh Harvinder, Winnie Siew Swee Chee, Bak Leong Goh, Halim A. Gafor, Sunita Bavanandan, Ghazali Ahmad and Tilakavati Karupaiah
    Citation: BMC Nephrology 2015 16:99
    Content type: Research article Published on:

  7. Although metabolomic approaches have begun to document numerous changes that arise in end stage renal disease (ESRD), how these alterations relate to established metabolic phenotypes in uremia is unknown.

    Authors: Sahir Kalim, Clary B. Clish, Joseph J. Deferio, Guillermo Ortiz, Alexander S. Moffet, Robert E. Gerszten, Ravi Thadhani and Eugene P. Rhee
    Citation: BMC Nephrology 2015 16:98
    Content type: Research article Published on:

  8. Periodontal disease is associated with increased mortality in the general population, however its prognostic significance in chronic kidney disease (CKD) is not known. We evaluated the joint effect of periodon...

    Authors: Ana C. Ricardo, Ambarish Athavale, Jinsong Chen, Hemanth Hampole, Daniel Garside, Phillip Marucha and James P. Lash
    Citation: BMC Nephrology 2015 16:97
    Content type: Research article Published on:

  9. Chronic kidney disease (CKD) is a major threat to the health of people of African ancestry. We assessed the prevalence and risk factors of CKD among adults in urban Cameroon.

    Authors: Francois Folefack Kaze, Marie-Patrice Halle, Hermine Tchuendem Mopa, Gloria Ashuntantang, Hermine Fouda, Jeanne Ngogang and Andre-Pascal Kengne
    Citation: BMC Nephrology 2015 16:96
    Content type: Research article Published on:

  10. Chronic kidney disease (CKD) is associated with an increased mortality rate, risk of cardiovascular events and morbidity. Impaired renal function is common in elderly patients, and their glomerular filtration ...

    Authors: Willemijn L. Eppenga, Wietske N. Wester, Hieronymus J. Derijks, Rein M.J. Hoedemakers, Michel Wensing, Peter A.G.M. De Smet and Rob J. Van Marum
    Citation: BMC Nephrology 2015 16:95
    Content type: Study protocol Published on:

  11. Chronic kidney disease (CKD) is a global challenge. Risk models to predict prevalent undiagnosed CKD have been published. However, none was developed or validated in an African population. We validated the Kor...

    Authors: Amelie Mogueo, Justin B. Echouffo-Tcheugui, Tandi E. Matsha, Rajiv T. Erasmus and Andre P. Kengne
    Citation: BMC Nephrology 2015 16:94
    Content type: Research article Published on:

  12. The leading cause of death in end stage renal disease is cardiovascular disease (CVD). Kidney transplantation is associated with improved survival over dialysis. We hypothesized that arterial stiffness, a mark...

    Authors: Kelly Ann Birdwell, Gilad Jaffe, Aihua Bian, Pingsheng Wu and Talat Alp Ikizler
    Citation: BMC Nephrology 2015 16:93
    Content type: Research article Published on:

  13. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis is a rare autosomal recessive renal disease characterized by tubular disorders at the thick ascending limb of Henle’s loop. It is caused by muta...

    Authors: Paulo Marcio Yamaguti, Pollyanna Almeida Costa dos Santos, Bruno Sakamoto Leal, Viviane Brandão Bandeira de Mello Santana, Juliana Forte Mazzeu, Ana Carolina Acevedo and Francisco de Assis Rocha Neves
    Citation: BMC Nephrology 2015 16:92
    Content type: Case report Published on:

  14. A number of studies have provided information regarding the risks and benefits of mammalian target of rapamycin inhibitors (mTOR-I) combined with calcineurin inhibitors (CNI) versus mycophenolic acid (MPA).

    Authors: Xishao Xie, Yan Jiang, Xiuxiu Lai, Shilong Xiang, Zhangfei Shou and Jianghua Chen
    Citation: BMC Nephrology 2015 16:91
    Content type: Research article Published on:

  15. The recently suggested distinct pathogenic pathways for myeloperoxidase (MPO) and proteinase 3 (PR3) anti-neutrophilic cytoplasmic antibodies (ANCA) associated vasculitis could result in different modes of pre...

    Authors: Iuliana Andreiana, Simona Stancu, Andreea Avram, Ludmila Taran and Gabriel Mircescu
    Citation: BMC Nephrology 2015 16:90
    Content type: Research article Published on:

  16. The FAVOURED study is an international multicentre, double-blind, placebo-controlled trial which commenced recruitment in 2008 and examines whether omega-3 polyunsaturated fatty acids (omega-3 PUFAs) either al...

    Authors: Andrea K. Viecelli, Elaine Pascoe, Kevan R. Polkinghorne, Carmel Hawley, Peta-Anne Paul-Brent, Sunil V. Badve, Alan Cass, Stephane Heritier, Peter G. Kerr, Trevor A. Mori, Amanda Robertson, Hooi L. Seong and Ashley B. Irish
    Citation: BMC Nephrology 2015 16:89
    Content type: Study protocol Published on:

  18. Inflammation is considered one of the major causes of protein-energy wasting in maintenance hemodialysis (MHD) patients. It is unclear whether dietary interventions can impact nutritional status and quality of...

    Authors: Srinivasan Beddhu, Rebecca Filipowicz, Xiaorui Chen, Jill L Neilson, Guo Wei, Yufeng Huang and Tom Greene
    Citation: BMC Nephrology 2015 16:87
    Content type: Research article Published on:

  19. Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common hereditary kidney diseases that frequently result in renal failure. In this cross-sectional observational cohort study, we evaluat...

    Authors: Hayne Cho Park, Ah-Young Kang, Joon Young Jang, Hyunsuk Kim, Miyeun Han, Kook-Hwan Oh, Seung Hyup Kim, Jung Woo Noh, Hae Il Cheong, Young-Hwan Hwang and Curie Ahn
    Citation: BMC Nephrology 2015 16:86
    Content type: Research article Published on:

  20. It is widely accepted that metabolic syndrome is associated with an increased risk of chronic kidney disease (CKD). To investigate whether coexisting metabolic syndrome is a necessary condition for CKD in over...

    Authors: Xia Cao, Jiansong Zhou, Hong Yuan, Liuxin Wu and Zhiheng Chen
    Citation: BMC Nephrology 2015 16:85
    Content type: Research article Published on:

  21. Studies suggest 24-h blood pressure (BP) variability has prognostic value for cardiovascular disease. Several factors associated with high 24-h BP variability are also common among individuals with chronic kid...

    Authors: Rikki M. Tanner, Daichi Shimbo, Albert W. Dreisbach, April P. Carson, Ervin R. Fox and Paul Muntner
    Citation: BMC Nephrology 2015 16:84
    Content type: Research article Published on:

  22. Chronic kidney disease (CKD) is highly prevalent in Taiwan. More than two-thirds of end-stage renal disease is associated with diabetes mellitus (DM) or hypertension (HTN). Therefore, the formulation of a spec...

    Authors: Sui-Lung Su, Chin Lin, SenYeong Kao, Chia-Chao Wu, Kuo-Cheng Lu, Ching-Huang Lai, Hsin-Yi Yang, Yu-Lung Chiu, Jin-Shuen Chen, Fung-Chang Sung, Ying-Chin Ko, Chien-Te Lee, Yu Yang, Chih-Wei Yang, Shang-Jyh Hwang, Ming-Cheng Wang…
    Citation: BMC Nephrology 2015 16:83
    Content type: Research article Published on:

  23. To evaluate the influence of parathyroid mass on the regulation of parathyroid hormone (PTH) secretion, we investigated the relationship between the resected parathyroid gland in total parathyroidectomy and th...

    Authors: Li Fang, Bing Tang, Dawei Hou, Meijuan Meng, Mingxia Xiong and Junwei Yang
    Citation: BMC Nephrology 2015 16:82
    Content type: Research article Published on:

  24. Chronic refractory hypotension is a rare but significant mortality risk in renal failure patients. Such aberrant physiology usually deems patient unfit for renal transplant surgery. Exercise stimulates the mec...

    Authors: Alice Rogan, Gordon McGregor, Charles Weston, Nithya Krishnan, Robert Higgins, Daniel Zehnder and Stephen M.S. Ting
    Citation: BMC Nephrology 2015 16:81
    Content type: Case report Published on:

  25. Evidence supports high prevalence of periodontitis in patients with chronic kidney disease. Several renal factors have been proposed as possible modifiers of periodontitis pathogenesis in this population. In t...

    Authors: Michel V. Furtado Araújo, Bo-Young Hong, Philip L. Fava, Shiza Khan, Joseph A. Burleson, George Fares, Wilner Samson, Linda D. Strausbaugh, Patricia I. Diaz and Effie Ioannidou
    Citation: BMC Nephrology 2015 16:80
    Content type: Research article Published on:

  26. In patients undergoing maintenance hemodialysis (HD), hyporesponsiveness to erythropoiesis stimulating agents (ESAs) is associated with adverse clinical outcomes. Systemic inflammation is highly prevalent in H...

    Authors: Matthew B. Rivara, T. Alp Ikizler, Charles D. Ellis, Rajnish Mehrotra and Jonathan Himmelfarb
    Citation: BMC Nephrology 2015 16:79
    Content type: Research article Published on:

  27. The objective of the study was to determine the relationship between common carotid artery intima-media thickness (CCA-IMT) and histologically assessed calcification of radial artery in relation to clinical fe...

    Authors: Katarzyna Janda, Marcin Krzanowski, Mariusz Gajda, Paulina Dumnicka, Danuta Fedak, Grzegorz J. Lis, Piotr Jaśkowski, Agata Pietrzycka, Jan A. Litwin and Władysław Sułowicz
    Citation: BMC Nephrology 2015 16:78
    Content type: Research article Published on:

  28. We studied the association of inflammatory biomarkers including C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6) with chronic kidney disease (CKD).

    Authors: Belinda T. Lee, Faheemuddin A. Ahmed, L. Lee Hamm, Federico J. Teran, Chung-Shiuan Chen, Yanxi Liu, Kamal Shah, Nader Rifai, Vecihi Batuman, Eric E. Simon, Jiang He and Jing Chen
    Citation: BMC Nephrology 2015 16:77
    Content type: Research article Published on:

  29. Adult cardiac surgery is significantly associated with the development of acute kidney injury (AKI). Still, the incidence and outcomes of AKI vary according to its definition. Our retrospective monocentric stu...

    Authors: Marc-Gilbert Lagny, François Jouret, Jean-Noël Koch, Francine Blaffart, Anne-Françoise Donneau, Adelin Albert, Laurence Roediger, Jean-Marie Krzesinski and Jean-Olivier Defraigne
    Citation: BMC Nephrology 2015 16:76
    Content type: Research article Published on:

  30. Renal involvement in sickle cell disease (SCD) contributes significantly to morbidity and mortality. The aim of this study was to determine the prevalence of chronic kidney disease (CKD) amongst SCD patients, ...

    Authors: Richard Kobina Dadzie Ephraim, Derick Nii Mensah Osakunor, Obed Cudjoe, Enos Amoako Oduro, Lyudmila Asante-Asamani, Juliana Mitchell, Hope Agbodzakey and Prince Adoba
    Citation: BMC Nephrology 2015 16:75
    Content type: Research article Published on:

  32. Streptococcus uberis, the most frequent cause of mastitis in lactating cows, is considered non-pathogenic for humans. Only a few case reports have described human infections with this microorganism, which is noto...

    Authors: Christine Valentiny, Harald Dirschmid and Karl Lhotta
    Citation: BMC Nephrology 2015 16:73
    Content type: Case report Published on:

  34. Mutations in several genes expressed in podocytes, including Cd2ap, have been associated with focal segmental glomerulosclerosis in humans. Mutant mouse models provide an opportunity to better understand the mole...

    Authors: Eric W. Brunskill and S. Steven Potter
    Citation: BMC Nephrology 2015 16:71
    Content type: Research article Published on:

  35. The main short-term advantages of haemodiafiltration (HDF) are supposedly better removal of Beta2-microglobulin (ß2-m) and phosphate, and better haemodynamic stability. The main disadvantage is higher costs. T...

    Authors: Guillaume Jean, Jean-Marc Hurot, Patrik Deleaval, Brice Mayor and Christie Lorriaux
    Citation: BMC Nephrology 2015 16:70
    Content type: Research article Published on:

  36. Chronic Kidney Disease (CKD) is a public health problem and there is a scarcity of type 2 CKD translational research that incorporates educational tools. Patient navigators have been shown to be effective at r...

    Authors: Stacey E Jolly, Sankar D Navaneethan, Jesse D Schold, Susana Arrigain, Victoria Konig, Yvette K Burrucker, Jennifer Hyland, Priscilla Dann, Barbara H Tucky, John W Sharp and Joseph V Nally
    Citation: BMC Nephrology 2015 16:69
    Content type: Research article Published on:

  37. Fructose acutely raises serum uric acid in normal subjects, but the effect in subjects with metabolic syndrome or subjects with chronic kidney disease is unknown. The aim of the study was to evaluate changes i...

    Authors: Rafał Donderski, Ilona Miśkowiec-Wiśniewska, Marek Kretowicz, Magdalena Grajewska, Jacek Manitius, Anna Kamińska, Roman Junik, Joanna Siódmiak, Anna Stefańska, Grażyna Odrowąż-Sypniewska, Agnieszka Pluta, Miguel Lanaspa and Richard J Johnson
    Citation: BMC Nephrology 2015 16:68
    Content type: Research article Published on:

  38. The aim of the US dialysis Prospective Payment System bundle, launched in January 2011, was reduction and more accurate prediction of costs of services, whilst maintaining or improving patient care. Dialysis f...

    Authors: Keri L Monda, Parveen Nedra Joseph, Peter J Neumann, Brian D Bradbury and Robert J Rubin
    Citation: BMC Nephrology 2015 16:67
    Content type: Research article Published on:

  39. Chronic kidney disease is strongly linked to neurocognitive deficits in adults and children, but the pathophysiologic processes leading to these deficits remain poorly understood. The NiCK study (Neurocognitiv...

    Authors: Erum A Hartung, Nina Laney, Ji Young Kim, Rebecca L Ruebner, John A Detre, Hua-Shan Liu, Christos Davatzikos, Guray Erus, Jimit J Doshi, Robert T Schultz, John D Herrington, Abbas F Jawad, Divya G Moodalbail, Ruben C Gur, Allison M Port, Jerilynn Radcliffe…
    Citation: BMC Nephrology 2015 16:66
    Content type: Study protocol Published on:

  40. Reliable estimates of the impacts of chronic kidney disease (CKD) stage, with and without cardiovascular disease, on hospital costs are needed to inform health policy.

    Authors: Seamus Kent, Iryna Schlackow, Jingky Lozano-Kühne, Christina Reith, Jonathan Emberson, Richard Haynes, Alastair Gray, Alan Cass, Colin Baigent, Martin J Landray, William Herrington and Borislava Mihaylova
    Citation: BMC Nephrology 2015 16:65
    Content type: Research article Published on:

  41. Amyloidosis leads to deposition of abnormal protein with beta-pleated sheet structure in specific compartments of the affected organs. The histological localization of these amyloid deposits determines the ove...

    Authors: Ekaterina Castano, Matthew B Palmer, Christine Vigneault, Randy Luciano, Serena Wong and Gilbert Moeckel
    Citation: BMC Nephrology 2015 16:64
    Content type: Research article Published on:

  42. Sudden cardiac death occurs commonly in the end-stage renal disease population receiving dialysis, with 25% dying of sudden cardiac death over 5 years. Despite this high risk, surprisingly few prospective stud...

    Authors: Rulan S Parekh, Lucy A Meoni, Bernard G Jaar, Stephen M Sozio, Tariq Shafi, Gordon F Tomaselli, Joao A Lima, Larisa G Tereshchenko, Michelle M Estrella and W H Linda Kao
    Citation: BMC Nephrology 2015 16:63
    Content type: Study protocol Published on:

  43. Chronic kidney disease (CKD) accelerates vascular stiffening related to age. Arterial stiffness may be evaluated measuring the carotid-femoral pulse wave velocity (PWV) or more simply, as recommended by KDOQI,...

    Authors: Igor Salvadé, Sibylle Schätti-Stählin, Eleonora Violetti, Carlo Schönholzer, Claudio Cereghetti, Hugo Zwahlen, Lorenzo Berwert, Michel Burnier and Luca Gabutti
    Citation: BMC Nephrology 2015 16:62
    Content type: Research article Published on:

  44. Chronic kidney disease (CKD) and systemic inflammation are risk factors for sepsis. While often viewed as a marker of chronic kidney disease, Cystatin C (Cyst-C) may also reflect systemic inflammation. We soug...

    Authors: Thomas Clark Powell, John P Donnelly, Orlando M Gutiérrez, Russell L Griffin, Monika M Safford and Henry E Wang
    Citation: BMC Nephrology 2015 16:61
    Content type: Research article Published on:

  46. Data regarding the epidemiology of end-stage renal disease (ESRD) and dialysis in sub-Saharan Africa are scarce and knowledge about the spectrum renal disease is very limited. This study is on the profile of p...

    Authors: Marie P Halle, Christian Takongue, Andre P Kengne, François F Kaze and Kathleen B Ngu
    Citation: BMC Nephrology 2015 16:59
    Content type: Research article Published on:

  47. Hyperuricemia may contribute to renal injury. We do not know whether use of treatments that lower urate reduce the progression of chronic kidney disease (CKD) and cardiovascular disease. We performed a systema...

    Authors: Tahir Kanji, Mandark Gandhi, Catherine M Clase and Robert Yang
    Citation: BMC Nephrology 2015 16:58
    Content type: Research article Published on:

  48. Multipass hemodialysis (MPHD) is a recently described dialysis modality, involving the use of small volumes of dialysate which are repetitively recycled. Dialysis regimes of 8 hours for six days a week using t...

    Authors: Sunny Eloot, Wim Van Biesen, Mette Axelsen, Griet Glorieux, Robert Smith Pedersen and James Goya Heaf
    Citation: BMC Nephrology 2015 16:57
    Content type: Research article Published on:

  49. Primary care providers do not routinely follow guidelines for the care of patients with chronic kidney disease (CKD). Multidisciplinary efforts may improve care for patients with chronic disease. Pharmacist ba...

    Authors: Danielle Cooney, Helen Moon, Yang Liu, Richard Tyler Miller, Adam Perzynski, Brook Watts and Paul E Drawz
    Citation: BMC Nephrology 2015 16:56
    Content type: Research article Published on:

  50. In western Nicaragua and El Salvador, chronic kidney disease (CKD) is highly prevalent and generally affects young, male, agricultural (usually sugar cane) workers without the established CKD risk factors. It ...

    Authors: Timothy S Laux, Joaquin Barnoya, Douglas R Guerrero and Marcos Rothstein
    Citation: BMC Nephrology 2015 16:54
    Content type: Research article Published on:
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BMC Nephrology

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