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  1. Little is known how health related quality of life (HRQOL) change in the transition from dialysis to renal transplantation (RTX). Longitudinal data addressing the patient-related outcomes are scarce, and parti...

    Authors: Nanna von der Lippe, Bård Waldum, Fredrik B Brekke, Amin AG Amro, Anna Varberg Reisæter and Ingrid Os
    Citation: BMC Nephrology 2014 15:191
  2. Excess extracellular volume is a major clinical problem in patients with chronic kidney disease (CKD). However, whether the extracellular volume status is associated with disease progression is unclear. We inv...

    Authors: Reibin Tai, Yasushi Ohashi, Sonoo Mizuiri, Atsushi Aikawa and Ken Sakai
    Citation: BMC Nephrology 2014 15:189
  3. Impairments of health related quality of life (HRQoL) are frequently observed in Fabry disease (FD) and are known to be related to neuropathic pain and cardiovascular events. This study aimed to explore the ro...

    Authors: Martin Wagner, Johannes Krämer, Elisabeth Blohm, Dorothee Vergho, Frank Weidemann, Frank Breunig and Christoph Wanner
    Citation: BMC Nephrology 2014 15:188
  4. Only a subset of patients who enter stage 3 chronic kidney disease (CKD) progress to stage 4. Identifying which patients entering stage 3 are most likely to progress could improve outcomes, by allowing more ap...

    Authors: Herbert S Chase, Jamie S Hirsch, Sumit Mohan, Maya K Rao and Jai Radhakrishnan
    Citation: BMC Nephrology 2014 15:187
  5. This study was aimed at determining the outcome and examining the association between comorbidities and mortality after intracerebral hemorrhage in chronic dialysis patients.

    Authors: Chun-Yu Lin, Chih-Chiang Chien, Hung-An Chen, Fu-Mei Su, Jhi-Joung Wang, Che-Chuan Wang, Chin-Chen Chu and Yeong-Jang Lin
    Citation: BMC Nephrology 2014 15:186
  6. Chronic Kidney Disease (CKD) is a major non-communicable chronic disease that is associated with adverse clinical and economic outcomes. Passive surveillance systems are likely to improve efforts for preventio...

    Authors: Austin G Stack, Liam F Casserly, Cornelius J Cronin, Tetyana Chernenko, Walter Cullen, Ailish Hannigan, Rajiv Saran, Howard Johnson, Gemma Browne and John P Ferguson
    Citation: BMC Nephrology 2014 15:185
  7. Mineral disorders are associated with adverse renal outcomes in chronic kidney disease (CKD) patients. Previous studies have associated hypercalcemia and hypocalcemia with mortality; however, the association b...

    Authors: Lee-Moay Lim, Hung-Tien Kuo, Mei-Chuan Kuo, Yi-Wen Chiu, Jia-Jung Lee, Shang-Jyh Hwang, Jer-Chia Tsai, Chi-Chih Hung and Hung-Chun Chen
    Citation: BMC Nephrology 2014 15:183
  8. Autosomal dominant polycystic kidney disease (ADPKD) causes progressive renal damage and is a leading cause of end-stage renal failure. With emerging therapies it is important to devise a method for early dete...

    Authors: Andrew P McGovern, Simon Jones, Jeremy van Vlymen, Anand K Saggar, Richard Sandford and Simon de Lusignan
    Citation: BMC Nephrology 2014 15:182
  9. This study aimed to compare the changes in kidney function and the association of tumor size and renal outcomes between patients with renal cell carcinoma (RCC) who underwent radical nephrectomy (RN) and those...

    Authors: Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Sun-Seog Kweon and Soo Wan Kim
    Citation: BMC Nephrology 2014 15:181
  10. Type 2 diabetes is a major risk factor for chronic kidney disease, which substantially increases the risk of cardiovascular disease mortality. This Phase IIb safety study (AleNephro) in patients with stage 3 c...

    Authors: Luis Ruilope, Markolf Hanefeld, A Michael Lincoff, Giancarlo Viberti, Sylvie Meyer-Reigner, Nadejda Mudie, Dominika Wieczorek Kirk, Klas Malmberg and Matthias Herz
    Citation: BMC Nephrology 2014 15:180
  11. Guidance varies regarding the optimal timing of arteriovenous fistula (AVF) creation. The aim of this study was to evaluate the association between uraemia, haemodialysis and early AVF failure.

    Authors: Emma Aitken, Andrew Jackson, Chia Kong, Paul Coats and David Kingsmore
    Citation: BMC Nephrology 2014 15:179
  12. Death receptors (DRs) play an important role in renal pathology. We have shown that DR3 is inducibly expressed on renal tubular epithelial cells in the setting of inflammatory injuries. In this study we invest...

    Authors: Jun Wang, Rafia S Al-Lamki, Xinwang Zhu, Hanzhe Liu, Jordan S Pober and John R Bradley
    Citation: BMC Nephrology 2014 15:178
  13. New information from various clinical settings suggests that tight blood pressure control may not reduce mortality and may be associated with more side effects.

    Authors: Adrian P Abreo, David Glidden, Patricia Painter, Janice Lea, Charles A Herzog, Nancy G Kutner and Kirsten L Johansen
    Citation: BMC Nephrology 2014 15:177
  14. In the current acute kidney injury (AKI) definition, the urine output (UO) criterion does not specify which body weights (BW), i.e. actual (ABW) versus ideal (IBW), should be used to diagnose and stage AKI, le...

    Authors: Charat Thongprayoon, Wisit Cheungpasitporn, Abbasali Akhoundi, Adil H Ahmed and Kianoush B Kashani
    Citation: BMC Nephrology 2014 15:176
  15. Collagen IV-related nephropathies, including thin basement membrane nephropathy and Alport Syndrome (AS), are caused by defects in the genes COL4A3, COL4A4 and COL4A5. Diagnosis of these conditions can be hindere...

    Authors: Fujun Lin, Fan Bian, Jun Zou, Xiangru Wu, Jianping Shan, Wei Lu, Yao Yao, Gengru Jiang and Daniel Philip Gale
    Citation: BMC Nephrology 2014 15:175
  16. Cardiovascular disease is a frequent cause of death in peritoneal dialysis patients. Biocompatible peritoneal dialysis solutions with neutral pH have been anticipated to reduce cardiovascular disease more than...

    Authors: Yoshifumi Hamasaki, Kent Doi, Mototsugu Tanaka, Haruki Kume, Yoshitaka Ishibashi, Yutaka Enomoto, Toshiro Fujita, Yukio Homma, Masaomi Nangaku and Eisei Noiri
    Citation: BMC Nephrology 2014 15:173
  17. Infrequent dialysis, namely once-a-week session combined with very low-protein, low-phosphorus diet supplemented with ketoacids was reported as a useful treatment schedule for ESRD patients with markedly reduc...

    Authors: Stefania Caria, Adamasco Cupisti, Giovanna Sau and Piergiorgio Bolasco
    Citation: BMC Nephrology 2014 15:172
  18. The Southeastern United States has the lowest kidney transplant rates in the nation, and racial disparities in kidney transplant access are concentrated in this region. The Southeastern Kidney Transplant Coali...

    Authors: Rachel E Patzer, Jennifer Gander, Leighann Sauls, M Ahinee Amamoo, Jenna Krisher, Laura L Mulloy, Eric Gibney, Teri Browne, Laura Plantinga and Stephen O Pastan
    Citation: BMC Nephrology 2014 15:171
  19. Hemodialysis patients (HD) need to adhere to a complex medication regimen. Because their daily pill burden is one of the highest reported, poor compliance is a major cause of therapeutic failure. The primary a...

    Authors: Inbal Cohen-Glickman, Yosef S Haviv and Matan J Cohen
    Citation: BMC Nephrology 2014 15:170
  20. Although intraperitoneal surgery is a major operation associated with postoperative acute kidney injury (AKI), the incidence, risk factors, and long-term renal outcome are not well known. We aimed to determine...

    Authors: Eunjung Cho, Sun-Chul Kim, Myung-Gyu Kim, Sang-Kyung Jo, Won-Yong Cho and Hyoung-Kyu Kim
    Citation: BMC Nephrology 2014 15:169
  21. Cardiovascular events (CVE) are more prevalent in chronic kidney disease (CKD) than in general population, being the main cause of morbimortality. Specific risk factors related to CKD have been suggested, beca...

    Authors: David Arroyo, Angels Betriu, Montserrat Martinez-Alonso, Teresa Vidal, Jose Manuel Valdivielso and Elvira Fernández
    Citation: BMC Nephrology 2014 15:168
  22. Early graft thrombosis and bleeding complications remain important causes of early graft loss following kidney transplantation in patients with antiphospholipid syndrome. Anti-β2-glycoprotein I IgG is a diseas...

    Authors: Tadashi Sofue, Yushi Hayashida, Taiga Hara, Kazuyo Kawakami, Nobufumi Ueda, Yoshio Kushida, Masashi Inui, Hiroaki Dobashi, Yoshiyuki Kakehi and Masakazu Kohno
    Citation: BMC Nephrology 2014 15:167
  23. Because of the deceased donor organ shortage, more kidney patients are considering whether to receive kidneys from family and friends, a process called living donor kidney transplantation (LDKT). Although Blac...

    Authors: Amy D Waterman, Mark L Robbins, Andrea L Paiva, John D Peipert, Crystal S Kynard-Amerson, Christina J Goalby, LaShara A Davis, Jessica L Thein, Emily A Schenk, Kari A Baldwin, Stacy L Skelton, Nicole R Amoyal and Leslie A Brick
    Citation: BMC Nephrology 2014 15:166
  24. Microalbuminuria has been shown to be a risk factor for cardiovascular and renal disease in patients with hypertension and diabetes as well as in the general population. Urinary albumin excretion over 24 h is ...

    Authors: Liuxia Yan, Jixiang Ma, Xiaolei Guo, Junli Tang, Jiyu Zhang, Zilong Lu, Huicheng Wang, Xiaoning Cai and Linhong Wang
    Citation: BMC Nephrology 2014 15:165
  25. Demineralisation and bone density loss during immobilisation are known phenomena. However information concerning the extent of calcium loss during immobilisation remains inconsistent within literature. This ma...

    Authors: Matthias Klingele, Sarah Seiler, Aaron Poppleton, Philip Lepper, Danilo Fliser and Roland Seidel
    Citation: BMC Nephrology 2014 15:163
  26. Uraemia is associated with a highly increased risk of cardiovascular disease. Mannose-binding lectin (MBL) has been shown to be involved in cardiovascular pathophysiology and a protective effect of MBL is sugg...

    Authors: Mads Hornum, Jakob T Bay, Peter Clausen, Jesper Melchior Hansen, Elisabeth R Mathiesen, Bo Feldt-Rasmussen and Peter Garred
    Citation: BMC Nephrology 2014 15:162
  27. Evidence suggests that high dose haemodialysis (HD) may be associated with better health outcomes and even cost savings (if conducted at home) versus conventional in-centre HD (ICHD). Home-based regimens such ...

    Authors: Frank Xiaoqing Liu, Catrin Treharne, Bruce Culleton, Lydia Crowe and Murat Arici
    Citation: BMC Nephrology 2014 15:161
  28. The definition of glomerular hyperfiltration has not been agreed upon and the pathophysiological mechanisms have not been well explored. Low serum creatinine concentrations may be associated with increased ris...

    Authors: Servet Altay, Altan Onat, Fatma Özpamuk-Karadeniz, Yusuf Karadeniz, Tuğba Kemaloğlu-Öz and Günay Can
    Citation: BMC Nephrology 2014 15:160
  29. This study aimed to measure the serum soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) and interleukin-17A (IL-17A) levels in hypertensive patients with/without asymptomatic organ damage (...

    Authors: Ihsan Ates, Nihal Özkayar, Fatma Akyel, Canan Topcuoglu, Serdar Akyel, A Nurdan Barça and Fatih Dede
    Citation: BMC Nephrology 2014 15:159
  30. Acute rejection (AR) and acute tubular necrosis (ATN) are main causes of early renal allograft dysfunction. Blood oxygen level-dependent magnetic resonance imaging (BOLD MRI) and Diffusion weighted (DW) MRI ca...

    Authors: Guangyi Liu, Fei Han, Wenbo Xiao, Qidong Wang, Ying Xu and Jianghua Chen
    Citation: BMC Nephrology 2014 15:158
  31. Fabry’s disease is a rare X-linked, hereditary lysosomal storage disease caused by a deficiency of the enzyme α-galactosidase A. Granulomatosis with polyangiitis is characterized by the involvement of the resp...

    Authors: Hironari Hanaoka, Akinori Hashiguchi, Konosuke Konishi, Tomohiro Ishii and Masataka Kuwana
    Citation: BMC Nephrology 2014 15:157
  32. Proteasome inhibitors are a relatively new class of chemotherapeutic agents. Bortezomib is the first agent of this class and is currently being used for the treatment of multiple myeloma. However, recent repor...

    Authors: Liliane Hobeika, Sally E Self and Juan Carlos Q Velez
    Citation: BMC Nephrology 2014 15:156
  33. We conducted this study to determine the erythrocyte glucose-6-phosphate dehydrogenase (G6PD) activity level in patients with end-stage renal disease (ESRD) on maintenance hemodialysis (HD) and to determine th...

    Authors: Mahmoud Husni Ayesh (Haj Yousef), Ahnaf Bataineh, Elham Elamin, Yousef Khader, Khaldoon Alawneh and Mohamad Rababah
    Citation: BMC Nephrology 2014 15:155
  34. Recent research has reported that patients receiving bolus (frequent large doses to achieve iron repletion) versus maintenance dosing of iron have an increased short-term risk of infection, but a similar risk ...

    Authors: Janet K Freburger, Alan R Ellis, Abhijit V Kshirsagar, Lily Wang and M Alan Brookhart
    Citation: BMC Nephrology 2014 15:154
  35. Chronic kidney disease (CKD) is public health concern even in Asian countries. TRK-100STP, a sustained release tablet of an orally-active prostacyclin analogue, beraprost sodium, is suggested to suppress worse...

    Authors: Hidetomo Nakamoto, Toshiro Fujita, Hideki Origasa, Masanao Isono, Hajimu Kurumatani, Kiyonobu Okada, Hiroyuki Kanoh, Takashi Kiriyama and Shunsuke Yamada
    Citation: BMC Nephrology 2014 15:153
  36. While chronic renal damage is a condition with low-grade inflammation, the potential role of inflammation in kidney disease as a marker of cardiovascular damage is of current interest. This study analyzed the ...

    Authors: Maria Udeanu, Giordano Guizzardi, Giuseppe Di Pasquale, Antonio Marchetti, Francesca Romani, Vittorio Dalmastri, Irene Capelli, Lucia Stalteri, Giuseppe Cianciolo, Paola Rucci and Gaetano La Manna
    Citation: BMC Nephrology 2014 15:152
  37. Baroreflex failure syndrome is a rare disorder which causes labile blood pressure, headache, flushing, diaphoresis and emotional lability. It is caused by history of trauma or radiotherapy in the cervical legi...

    Authors: Natsumi Tanabe, Koki Takane, Keitaro Yokoyama, Yudo Tanno, Izumi Yamamoto, Ichiro Ohkido and Takashi Yokoo
    Citation: BMC Nephrology 2014 15:151
  38. The presence of chronic kidney disease (CKD) in type 2 diabetes mellitus (T2DM) increases the risk of cardiovascular disease (CVD) regardless of the presence of traditional cardiovascular risk factors. There i...

    Authors: Antonio Rodriguez-Poncelas, Gabriel Coll-De Tuero, Oriol Turrò-Garriga, Joan Barrot-de la Puente, Josep Franch-Nadal and Xavier Mundet-Tuduri
    Citation: BMC Nephrology 2014 15:150
  39. Cancer antigen 125 (CA125) is made by peritoneal mesothelial cells and can be measured in spent dialysate effluent from peritoneal dialysis (PD) patients. It has been suggested that CA125 is a marker of perito...

    Authors: Kwanpeemai Panorchan and Andrew Davenport
    Citation: BMC Nephrology 2014 15:149
  40. Weight gain and obesity are common after kidney transplantation, particularly during the first year. Obesity is a risk factor for the development of new-onset diabetes after transplantation, and is associated ...

    Authors: Kristin J Ryan, Jessie M Segedin Casas, Laura E Mash, Sandra L McLellan, Lyn E Lloyd, James W Stinear, Lindsay D Plank and Michael G Collins
    Citation: BMC Nephrology 2014 15:148
  41. Expression and/or excretion of fibroblast growth factor-23 (FGF23) and its co-receptor Klotho are altered in patients with end-stage renal disease. The possibility that the FGF23/α-Klotho system mediates the a...

    Authors: Michishige Ozeki, Shu-ichi Fujita, Shun Kizawa, Hideaki Morita, Koichi Sohmiya, Masaaki Hoshiga and Nobukazu Ishizaka
    Citation: BMC Nephrology 2014 15:147
  42. Microalbuminuria is a marker of early kidney disease and high cardiovascular risk in various populations, including HIV positive patients. However, the diagnostic value of qualitative (dipstick) proteinuria an...

    Authors: Mannix Imani Masimango, Ernest Kiswaya Sumaili, Michel Jadoul, Pierre Wallemacq, Dieudonné Kanigula Mubagwa, Rissassy Jean-Robert Makulo, François Bompeka Lepira and Nazaire Mangani Nseka
    Citation: BMC Nephrology 2014 15:146
  43. Matrix Gla protein (MGP) is known to act as a potent local inhibitor of vascular calcifications. However, in order to be active, MGP must be phosphorylated and carboxylated, with this last process being depend...

    Authors: Pierre Delanaye, Jean-Marie Krzesinski, Xavier Warling, Martial Moonen, Nicole Smelten, Laurent Médart, Hans Pottel and Etienne Cavalier
    Citation: BMC Nephrology 2014 15:145
  44. The use of herbal medicine may be a risk factor for the development of kidney injury, as it has been reported to cause various renal syndromes. Dioscorea quinqueloba is a medicinal herb that is used as an alterna...

    Authors: Ha Yeon Kim, Sung Sun Kim, Soo Hyeon Bae, Eun Hui Bae, Seong Kwon Ma and Soo Wan Kim
    Citation: BMC Nephrology 2014 15:143
  45. Focal segmental glomerulosclerosis (FSGS) is a glomerular scarring disease diagnosed mostly by kidney biopsy. Since there is currently no diagnostic test that can accurately predict steroid responsiveness in F...

    Authors: Shiva Kalantari, Mohsen Nafar, Dorothea Rutishauser, Shiva Samavat, Mostafa Rezaei-Tavirani, Hongqian Yang and Roman A Zubarev
    Citation: BMC Nephrology 2014 15:141
  46. To evaluate the effects of contrast agents containing increasing concentrations of iodine on the renal oxygenation level determined by blood oxygenation level dependent (BOLD) magnetic resonance imaging (MRI) ...

    Authors: Jia-huan Wang, Ke Ren, Wen-ge Sun, Li Zhao, Hong-shan Zhong and Ke Xu
    Citation: BMC Nephrology 2014 15:140

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