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  1. Because of the absorption of glucose in peritoneal dialysis (PD) solution, PD patients show an atherogenic lipid profile, which is predictive of poor survival in PD patients. Lipoprotein subclasses consist of ...

    Authors: Eiichiro Kanda, Masumi Ai, Asami Iwamoto, Mitsuyo Okazaki, Yoshitaka Maeda, Sei Sasaki and Masayuki Yoshida
    Citation: BMC Nephrology 2013 14:234
    Content type: Research article Published on:

  3. Recent guidelines suggest the adoption of regional citrate anticoagulation (RCA) as first choice CRRT anticoagulation modality in patients without contraindications for citrate. Regardless of the anticoagulati...

    Authors: Santo Morabito, Valentina Pistolesi, Luigi Tritapepe, Elio Vitaliano, Laura Zeppilli, Francesca Polistena, Enrico Fiaccadori and Alessandro Pierucci
    Citation: BMC Nephrology 2013 14:232
    Content type: Research article Published on:

  4. Accumulated to-date microarray data on ischemia reperfusion injury (IRI) of kidney represent a powerful source for identifying new targets and mechanisms of kidney IRI. In this study, we conducted a meta-analy...

    Authors: Dmitry N Grigoryev, Dilyara I Cheranova, Daniel P Heruth, Peixin Huang, Li Q Zhang, Hamid Rabb and Shui Q Ye
    Citation: BMC Nephrology 2013 14:231
    Content type: Technical advance Published on:

  5. The National Kidney Foundation (NKF) Kidney Disease Outcomes Quality Initiative (KDOQI) developed guidelines to care for patients with chronic kidney disease (CKD). While these are disseminated through the NKF...

    Authors: Michelle M Estrella, Bernard G Jaar, Kerri L Cavanaugh, Chester H Fox, Mark A Perazella, Sandeep S Soman, Emily Howell, Michael V Rocco and Michael J Choi
    Citation: BMC Nephrology 2013 14:230
    Content type: Research article Published on:

  6. Cardiac troponin T is independently associated with cardiovascular events and mortality in patients with chronic kidney disease (CKD). Serum levels of high sensitivity cardiac troponin T (hs-TnT) reflect subcl...

    Authors: Ruth F Dubin, Yongmei Li, Jiang He, Bernard G Jaar, Radhakrishna Kallem, James P Lash, Gail Makos, Sylvia E Rosas, Elsayed Z Soliman, Ray R Townsend, Wei Yang, Alan S Go, Martin Keane, Christopher deFilippi, Rakesh Mishra, Myles Wolf…
    Citation: BMC Nephrology 2013 14:229
    Content type: Research article Published on:

  7. Frailty is a condition characterized by a decline in physical function and functional capacity. Common symptoms of frailty, such as weakness and exhaustion, are prevalent in patients with chronic kidney diseas...

    Authors: Simon R Walker, Kamalpreet Gill, Kerry Macdonald, Paul Komenda, Claudio Rigatto, Manish M Sood, Clara J Bohm, Leroy J Storsley and Navdeep Tangri
    Citation: BMC Nephrology 2013 14:228
    Content type: Research article Published on:

  8. Acute kidney injury (AKI) severely worsens prognosis of hospitalized patients. Early Endothelial Outgrowth Cells act protective in murine acute ischemic renal failure and renoprotective actions of eEOCs have b...

    Authors: Daniel Patschan, Jörg Rinneburger, Nazif Idrizi, Rico Backhaus, Katrin Schwarze, Elvira Henze, Susann Patschan and Gerhard A Müller
    Citation: BMC Nephrology 2013 14:227
    Content type: Research article Published on:

  9. Chronic kidney disease–mineral and bone disorder (CKD–MBD) is a common complication in CKD patients, particularly in those with end-stage renal disease that requires dialysis. Lanthanum carbonate (LC) is a pot...

    Authors: Chenglong Zhang, Ji Wen, Zi Li and Junming Fan
    Citation: BMC Nephrology 2013 14:226
    Content type: Research article Published on:

  10. Balkan endemic nephropathy (BEN) represents a chronic progressive interstitial nephritis in striking correlation with uroepithelial tumours of the upper urinary tract. The disease has endemic distribution in t...

    Authors: Rada Staneva, Blaga Rukova, Savina Hadjidekova, Desislava Nesheva, Olga Antonova, Plamen Dimitrov, Valeri Simeonov, Georgi Stamenov, Rade Cukuranovic, Jovana Cukuranovic, Vladislav Stefanovic, Momir Polenakovic, Ivanka Dimova, Ruslan Hlushchuk, Valentin Djonov, Angel Galabov…
    Citation: BMC Nephrology 2013 14:225
    Content type: Research article Published on:

  11. Patients undergoing hemodialysis are at high risk of falls, with subsequent complications including fractures, loss of independence, hospitalization, and institutionalization. Factors associated with falls are...

    Authors: Mara A McAdams-DeMarco, Sunitha Suresh, Andrew Law, Megan L Salter, Luis F Gimenez, Bernard G Jaar, Jeremy D Walston and Dorry L Segev
    Citation: BMC Nephrology 2013 14:224
    Content type: Research article Published on:

  12. Chronic progressive mesangioproliferative nephropathy represents a major cause of end-stage renal disease worldwide. Until now, effective approaches to stop or even slow its progression are limited. We tested ...

    Authors: Yingrui Wang-Rosenke, Dymtro Khadzhynov, Tanja Loof, Alice Mika, Hiroshi Kawachi, Hans-H Neumayer and Harm Peters
    Citation: BMC Nephrology 2013 14:223
    Content type: Research article Published on:

  13. Bixalomer (BXL) was developed to improve gastrointestinal symptoms and reduce constipation, relative to sevelamer hydrochloride, in hemodialysis patients. We prospectively evaluated the safety and effectivenes...

    Authors: Shingo Hatakeyama, Hiromi Murasawa, Takuma Narita, Masaaki Oikawa, Naoki Fujita, Hiromichi Iwamura, Joutaro Mikami, Yuta Kojima, Tendo Sato, Ken Fukushi, Yusuke Ishibashi, Yasuhiro Hashimoto, Takuya Koie, Hisao Saitoh, Tomihisa Funyu and Chikara Ohyama
    Citation: BMC Nephrology 2013 14:222
    Content type: Research article Published on:

  14. Vascular calcification (VC) contributes to high mortality rates in chronic kidney disease (CKD). High serum phosphate and FGF23 levels and impaired phosphaturic response to FGF23 may affect VC. Therefore, thei...

    Authors: Lourdes Craver, Adriana Dusso, Montserrat Martinez-Alonso, Felipe Sarro, José M Valdivielso and Elvira Fernández
    Citation: BMC Nephrology 2013 14:221
    Content type: Research article Published on:

  15. Poor sleep quality (SQ) and daytime sleepiness (DS) are common in renal transplant (RTx) recipients; however, related data are rare. This study describes the prevalence and frequency of self-reported sleep dis...

    Authors: Hanna Burkhalter, Daniel P Brunner, Anna Wirz-Justice, Christian Cajochen, Terri E Weaver, Jürg Steiger, Thomas Fehr, Reto M Venzin and Sabina De Geest
    Citation: BMC Nephrology 2013 14:220
    Content type: Research article Published on:

  16. Sclerostin is a Wnt pathway antagonist regulating osteoblast activity and bone turnover. Here, we assessed the potential association of sclerostin with the development of coronary artery (CAC) and aortic valve...

    Authors: Vincent M Brandenburg, Rafael Kramann, Ralf Koos, Thilo Krüger, Leon Schurgers, Georg Mühlenbruch, Sinah Hübner, Ulrich Gladziwa, Christiane Drechsler and Markus Ketteler
    Citation: BMC Nephrology 2013 14:219
    Content type: Research article Published on:

  17. Accurate blood pressure monitoring is critical for the management of chronic kidney disease, but changes in management in secondary care clinics may be based on a single blood pressure reading, with a subseque...

    Authors: Shona Brothwell, Mary Dutton, Charles Ferro, Stephanie Stringer and Paul Cockwell
    Citation: BMC Nephrology 2013 14:218
    Content type: Research article Published on:

  18. Blood transfusions have the potential to improve graft survival, induce sensitization, and transmit infections. Current clinical practice is to minimize transfusions in renal transplantation candidates, but it...

    Authors: Juan C Scornik, Jonathan S Bromberg, Douglas J Norman, Mayank Bhanderi, Matthew Gitlin and Jeffrey Petersen
    Citation: BMC Nephrology 2013 14:217
    Content type: Research article Published on:

  19. The majority of bicarbonate based dialysis fluids are acidified with acetate. Citrate, a well known anticoagulant and antioxidant, has been suggested as a biocompatible alternative. The objective of this study...

    Authors: Gunilla Grundström, Anders Christensson, Maria Alquist, Lars-Göran Nilsson and Mårten Segelmark
    Citation: BMC Nephrology 2013 14:216
    Content type: Research article Published on:

  20. Chronic kidney disease (CKD) is one of the most serious public health problems. The increasing prevalence of CKD in developed and developing countries has led to a global epidemic. The hypothesis proposed is t...

    Authors: Israel dos Reis Santos, Aline Roberta Danaga, Isabella de Carvalho Aguiar, Ezequiel Fernandes Oliveira, Ismael Souza Dias, Jessica Julioti Urbano, Aline Almeida Martins, Leonardo Macario Ferraz, Nina Teixeira Fonsêca, Virgilio Fernandes, Vinicius Alves Thomaz Fernandes, Viviane Cristina Delgado Lopes, Fernando Sérgio Studart Leitão Filho, Sérgio Roberto Nacif, Paulo de Tarso Camillo de Carvalho, Luciana Maria Malosá Sampaio…
    Citation: BMC Nephrology 2013 14:215
    Content type: Study protocol Published on:

  21. To investigate gene expression of podocyte-specific proteins in urine of diabetes and prediabetes subjects and the association of these proteins with albuminuria.

    Authors: Jonathan Fraportti do Nascimento, Luis H Canani, Fernando Gerchman, Patricia G Rodrigues, Gabriel Joelsons, Mariane dos Santos, Sane Pereira and Francisco V Veronese
    Citation: BMC Nephrology 2013 14:214
    Content type: Research article Published on:

  22. Stress-induced cardiomyopathy (sCMP) is characterized by transient wall-motion abnormalities involving the left ventricular apex and mid-ventricle that are precipitated by emotional or physical stress. As the ...

    Authors: Min Ji Shin, Harin Rhee, Il Young Kim, Byeong Yun Yang, Sang Heon Song, Dong Won Lee, Soo Bong Lee, Ihm Soo Kwak, Jung Hyun Choi and Eun Young Seong
    Citation: BMC Nephrology 2013 14:213
    Content type: Research article Published on:

  23. Peripheral artery disease (PAD) represents atherosclerotic disease and is a risk factor for death in peritoneal dialysis (PD) patients, who tend to show an atherogenic lipid profile. In this study, we investig...

    Authors: Eiichiro Kanda, Masumi Ai, Mitsuyo Okazaki, Yoshitaka Maeda, Sei Sasaki and Masayuki Yoshida
    Citation: BMC Nephrology 2013 14:212
    Content type: Research article Published on:

  24. Chronic exposure to low cadmium (Cd) levels produces urinary excretion of low molecular weight proteins, which is considered the critical effect of Cd exposure. However, the mechanisms involved in Cd-induced p...

    Authors: Mitzi Paola Santoyo-Sánchez, José Pedraza-Chaverri, Eduardo Molina-Jijón, Laura Arreola-Mendoza, Rafael Rodríguez-Muñoz and Olivier Christophe Barbier
    Citation: BMC Nephrology 2013 14:211
    Content type: Research article Published on:

  25. Renal biopsies provide important diagnostic and prognostic information in ANCA associated glomerulonephritis. A new classification for prognostication of pauci-immune glomerulonephritis (GN) based on four cate...

    Authors: Carla L Ellis, Rebecca L Manno, John P Havill, Lorraine C Racusen and Duvuru Geetha
    Citation: BMC Nephrology 2013 14:210
    Content type: Research article Published on:

  26. Kidney injuries provoke considerable adjustment of renal physiology, metabolism, and architecture to nephron loss. Despite remarkable regenerative capacity of the renal tissue, these adaptations often lead to ...

    Authors: Larisa V Fedorova, Anita Tamirisa, David J Kennedy, Steven T Haller, Georgy Budnyy, Joseph I Shapiro and Deepak Malhotra
    Citation: BMC Nephrology 2013 14:209
    Content type: Research article Published on:

  27. Despite the evidence that phosphate binder (PB) is associated with improved outcomes many hemodialysis patients do not adhere to prescribed PB regimen. Therefore, barriers to PB adherence should be identified ...

    Authors: Maria Tereza Silveira Martins, Luciana Ferreira Silva, Angiolina Kraychete, Dandara Reis, Lidiane Dias, Gabriel Schnitman, Lívia Oliveira, Gildete Barreto Lopes and Antonio Alberto Lopes
    Citation: BMC Nephrology 2013 14:208
    Content type: Research article Published on:

  28. Polyomavirus BK nephropathy (PyVAN) remains an important cause of early graft dysfunction and graft loss in kidney transplantation.

    Authors: Johannes Jacobi, Antonina Prignitz, Maike Büttner, Klaus Korn, Alexander Weidemann, Karl F Hilgers, Katharina Heller, Joachim Velden, Antje Knöll, Bernd Wullich, Christoph May, Kai-Uwe Eckardt and Kerstin U Amann
    Citation: BMC Nephrology 2013 14:207
    Content type: Research article Published on:

  29. Vitamin D insufficiency is associated with proteinuria and could be a risk factor for end-stage renal disease (ESRD). However, few studies have examined the significance of vitamin D insufficiency as a contrib...

    Authors: Bancha Satirapoj, Pokkrong Limwannata, Amnart Chaiprasert, Ouppatham Supasyndh and Panbuppa Choovichian
    Citation: BMC Nephrology 2013 14:206
    Content type: Research article Published on:

  30. Phosphate binders’ constituents have alkalotic or acidotic properties and may contribute to acid base balance in haemodialysis patients. This study aimed to investigate the differential effects of phosphate bi...

    Authors: Zaw Thet, Aung Ko WIN, Eugenie Pedagogos, Jennifer Beavis, Sandra Crikis and Craig Nelson
    Citation: BMC Nephrology 2013 14:205
    Content type: Research article Published on:

  31. Exercise during hemodialysis treatments improves physical function, markers of cardiovascular disease and quality of life. However, exercise programs are not a part of standard therapy in the vast majority of ...

    Authors: Paul N Bennett, Robin M Daly, Steve F Fraser, Terry Haines, Robert Barnard, Cherene Ockerby and Bridie Kent
    Citation: BMC Nephrology 2013 14:204
    Content type: Study protocol Published on:

  32. Post-transplantation encapsulating peritoneal sclerosis (EPS) causing bowel obstruction has been identified as a serious complication after kidney transplantation in patients previously treated with peritoneal...

    Authors: Sayed Meelad Habib, Frank Johan Marinus Frederik Dor, Mario Richard Korte, Sander Martijn Hagen and Michiel Gerardus Henricus Betjes
    Citation: BMC Nephrology 2013 14:203
    Content type: Case report Published on:

  33. The renal distal nephron plays an important role in the maintenance of sodium balance, extra cellular volume and blood pressure. The degree of water transport, via aquaporin2 water channels (AQP2), and sodium ...

    Authors: Janni M Jensen, Frank H Mose, Jesper N Bech, Soren Nielsen and Erling B Pedersen
    Citation: BMC Nephrology 2013 14:202
    Content type: Research article Published on:

  34. Among African-Americans adults, arterial hypertension is both more prevalent and associated with more complications than among white adults. Hypertension is also epidemic among black adults in sub-Saharan Afri...

    Authors: Robert N Peck, Luke R Smart, Rita Beier, Anthony C Liwa, Heiner Grosskurth, Daniel W Fitzgerald and Bernhard MW Schmidt
    Citation: BMC Nephrology 2013 14:201
    Content type: Research article Published on:

  35. Responsiveness to erythropoiesis-stimulating agents (ESAs) varies widely among dialysis patients. ESA resistance has been associated with mortality in hemodialysis (HD) patients, but in peritoneal dialysis (PD...

    Authors: Marit M Suttorp, Tiny Hoekstra, Joris I Rotmans, Ilka Ott, Moshe Mittelman, Raymond T Krediet and Friedo W Dekker
    Citation: BMC Nephrology 2013 14:200
    Content type: Research article Published on:

  36. Vitamin D insufficiency correlates with mortality risk among patients with chronic kidney disease (CKD). The survival benefits of active vitamin D treatment have been assessed in patients with CKD not requirin...

    Authors: Zhenfeng Zheng, Huilan Shi, Junya Jia, Dong Li and Shan Lin
    Citation: BMC Nephrology 2013 14:199
    Content type: Research article Published on:

  37. Chronic kidney disease (CKD) is a known risk factor for cardiovascular events and all-cause mortality. We investigate the relationship between CKD stage, proteinuria, hypertension and these adverse outcomes in...

    Authors: Andrew P McGovern, Benjamin Rusholme, Simon Jones, Jeremy N van Vlymen, Harshana Liyanage, Hugh Gallagher, Charles RV Tomson, Kamlesh Khunti, Kevin Harris and Simon de Lusignan
    Citation: BMC Nephrology 2013 14:198
    Content type: Research article Published on:

  38. Ten years on from the National Institute of Health and Clinical Excellence’ technology appraisal guideline on haemodialysis in 2002; the clinical community is yet to rise to the challenge of providing home hae...

    Authors: Anuradha Jayanti, Alison J Wearden, Julie Morris, Paul Brenchley, Inger Abma, Steffen Bayer, James Barlow and Sandip Mitra
    Citation: BMC Nephrology 2013 14:197
    Content type: Study protocol Published on:

  40. HUPRA syndrome is a rare mitochondrial disease characterized by hyperuricemia, pulmonary hypertension, renal failure in infancy and alkalosis. This syndrome was previously described in three patients with a ho...

    Authors: Henry Rivera, Elena Martín-Hernández, Aitor Delmiro, María Teresa García-Silva, Pilar Quijada-Fraile, Rafael Muley, Joaquín Arenas, Miguel A Martín and Francisco Martínez-Azorín
    Citation: BMC Nephrology 2013 14:195
    Content type: Case report Published on:

  41. Restless Legs Syndrome is very common in hemodialysis patients however there are no comparative studies assessing the effectiveness of a non-pharmacological treatment to a classical treatment on parameters rel...

    Authors: Christoforos D Giannaki, Giorgos K Sakkas, Christina Karatzaferi, Georgios M Hadjigeorgiou, Eleftherios Lavdas, Theodoros Kyriakides, Yiannis Koutedakis and Ioannis Stefanidis
    Citation: BMC Nephrology 2013 14:194
    Content type: Research article Published on:

  42. Enhanced external counterpulsation (EECP) enhances coronary perfusion and reduces left ventricular afterload. However, the role of EECP on renal function in cardiac patients is unknown. Our aim was to assess r...

    Authors: Prajej Ruangkanchanasetr, Nithi Mahanonda, Ongkarn Raungratanaamporn, Piyanuj Ruckpanich, Chagriya Kitiyakara, Amnart Chaiprasert, Surawat Adirekkiat, Dollapas Punpanich, Somlak Vanavanan, Anchalee Chittamma and Thanom Supaporn
    Citation: BMC Nephrology 2013 14:193
    Content type: Research article Published on:

  43. There is a paucity of information about the views of dialysis nurses towards dialysis modality selection, yet nurses often have the most direct contact time with patients. We conducted a survey to better under...

    Authors: Karthik K Tennankore, Jay Hingwala, Diane Watson, Joanne M Bargman and Christopher T Chan
    Citation: BMC Nephrology 2013 14:192
    Content type: Research article Published on:

  44. In the general population, reported levels of oxidative stress and antioxidant potential seem to vary. The aim of this study was to investigate the levels of oxidant status markers in relation to estimated glo...

    Authors: Yuko Ishizaka, Minoru Yamakado, Akiko Toda, Mizuki Tani and Nobukazu Ishizaka
    Citation: BMC Nephrology 2013 14:191
    Content type: Research article Published on:

  45. Polycystic kidney diseases (PKD) are a group of monogenic disorders that are inherited dominantly (autosomal dominant PKD; ADPKD) or recessively, including, autosomal recessive PKD (ARPKD). A number of recessi...

    Authors: Reza Vazifehmand, Sandro Rossetti, Sassan Saber, Hamid Reza Khorram Khorshid and Peter C Harris
    Citation: BMC Nephrology 2013 14:190
    Content type: Case report Published on:

  46. Haemodialysis patients have an increased prevalence of hypertension and risk of cardiovascular mortality and stroke. Higher dialysate calcium concentrations have been reported to cause both an acute and chroni...

    Authors: Evangelia Charitaki and Andrew Davenport
    Citation: BMC Nephrology 2013 14:189
    Content type: Research article Published on:

  48. Hepatitis C virus (HCV) infection and chronic kidney disease (CKD) have high prevalences in Taiwan and worldwide, but the role of HCV infection in causing CKD remains uncertain. This cohort study aimed to expl...

    Authors: Yi-Chun Chen, Wen-Yen Chiou, Shih-Kai Hung, Yu-Chieh Su and Shang-Jyh Hwang
    Citation: BMC Nephrology 2013 14:187
    Content type: Research article Published on:

  49. Some 7-10% of patients on replacement renal therapy (RRT) are receiving it because of autosomal dominant polycystic kidney disease (ADPKD). The age at initiation of RRT is expected to increase over time.

    Authors: Víctor Martínez, Jordi Comas, Emma Arcos, Joan Manel Díaz, Salomé Muray, Juan Cabezuelo, José Ballarín, Elisabet Ars and Roser Torra
    Citation: BMC Nephrology 2013 14:186
    Content type: Research article Published on:

  50. The aim of this study was to evaluate whether a high baseline level of high-sensitivity C-reactive protein (hs-CRP) or changes in the level predicts the risk of peritonitis in patients on continuous ambulatory...

    Authors: Yu-Jen Su, Shang-Chih Liao, Ben-Chung Cheng, Jyh-Chang Hwang and Jin-Bor Chen
    Citation: BMC Nephrology 2013 14:185
    Content type: Research article Published on:
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BMC Nephrology

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