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  1. To facilitate in the identification of gene products important in regulating renal glomerular structure and function, we have produced an annotated transcriptome database for normal human glomeruli using the S...

    Authors: Jenny Nyström, Wolfgang Fierlbeck, Anna Granqvist, Stephen C Kulak and Barbara J Ballermann
    Citation: BMC Nephrology 2009 10:13
  2. Previous studies have examined the spectrum of diseases identified with a kidney biopsy and the complications of the procedure. However, few studies have examined the utility of the test to clarify the diagnos...

    Authors: Bari Scheckner, Alexandra Peyser, Jacob Rube, Freya Tarapore, Rachel Frank, Suzanne Vento, Cathy Hoffman, Elsa Valderrama, Douglas Charney, Beatrice Goilav and Howard Trachtman
    Citation: BMC Nephrology 2009 10:11
  3. Despite the characteristic extensive tubulointerstitial fibrosis, Balkan Endemic Nephropathy (BEN) is usually considered a non-inflammatory disease.

    Authors: Wilfried Karmaus, Plamen Dimitrov, Valeri Simeonov, Svetla Tsolova and Vecihi Batuman
    Citation: BMC Nephrology 2009 10:10
  4. Increased activation of the renin-angiotensin system (RAS) may be important in promoting coronary heart disease (CHD) and renal dysfunction, but limited data are available on associations between angiotensin t...

    Authors: Julie Lin, Frank B Hu, Lu Qi and Gary C Curhan
    Citation: BMC Nephrology 2009 10:9
  5. Patients on peritoneal and hemodialysis have accelerated atherosclerosis associated with an increase in cardiovascular morbidity and mortality. The atherosclerosis is associated with increased arterial stiffne...

    Authors: Robert G Fassett, Ritza Driver, Helen Healy, Dwarakanathan Ranganathan, Sharad Ratanjee, Iain K Robertson, Dominic P Geraghty, James E Sharman and Jeff S Coombes
    Citation: BMC Nephrology 2009 10:8
  6. A concentrate for bicarbonate haemodialysis acidified with citrate instead of acetate has been marketed in recent years. The small amount of citrate used (one-fifth of the concentration adopted in regional ant...

    Authors: Luca Gabutti, Barbara Lucchini, Claudio Marone, Lorenzo Alberio and Michel Burnier
    Citation: BMC Nephrology 2009 10:7
  7. In patients treated by maintenance hemodialysis the relationship to survival of hemoglobin level and administered epoetin-alfa and intravenous iron is controversial. The study aim was to determine effects on p...

    Authors: Victor E Pollak, Jonathan A Lorch, Rakesh Shukla and Supriya Satwah
    Citation: BMC Nephrology 2009 10:6
  8. Anaemia is common in patients with chronic kidney disease (CKD) and can be managed by therapy with erythropoiesis-stimulating agents (ESAs). Epoetin delta (DYNEPO®, Shire plc) is the only epoetin produced in a hu...

    Authors: Ulrich Frei, Jonathan TC Kwan and Bruce S Spinowitz
    Citation: BMC Nephrology 2009 10:5
  9. Chronic kidney disease (CKD) is increasingly being recognized as an emerging public health problem in India. However, community based estimates of low glomerular filtration rate (GFR) and proteinuria are few. ...

    Authors: Narinder P Singh, Gopal K Ingle, Vinay K Saini, Ajita Jami, Pankaj Beniwal, Madan Lal and Gajender S Meena
    Citation: BMC Nephrology 2009 10:4
  10. The use of peritoneal dialysis (PD) has declined in the United States over the past decade and technique failure is also reportedly higher in PD compared to hemodialysis (HD), but there are little data in the ...

    Authors: Bernard G Jaar, Laura C Plantinga, Deidra C Crews, Nancy E Fink, Nasser Hebah, Josef Coresh, Alan S Kliger and Neil R Powe
    Citation: BMC Nephrology 2009 10:3
  11. Exercise training in hemodialysis patients improves fitness, physical function, quality of life and markers of cardiovascular disease such as arterial stiffness. The majority of trials investigating this area ...

    Authors: Kirsten P Koh, Robert G Fassett, James E Sharman, Jeff S Coombes and Andrew D Williams
    Citation: BMC Nephrology 2009 10:2
  12. Haemodialysis (HD) is critically dependent on the availability of adequate access to the systemic circulation, ideally via a native arteriovenous fistula (AVF). The Primary failure rate of an AVF ranges betwee...

    Authors: Ashley Irish, Gursharan Dogra, Trevor Mori, Elaine Beller, Stephane Heritier, Carmel Hawley, Peter Kerr, Amanda Robertson, Johan Rosman, Peta-Anne Paul-Brent, Melissa Starfield, Kevan Polkinghorne and Alan Cass
    Citation: BMC Nephrology 2009 10:1
  13. The objective was to investigate the association between renal structural parameters and renal function. The structural parameters were renal cortical volume, total renal volume, number of glomeruli, and total...

    Authors: Anders B Lødrup, Kristian Karstoft, Thomas H Dissing, Jens R Nyengaard and Michael Pedersen
    Citation: BMC Nephrology 2008 9:18
  14. There is evidence that renal transplant recipients have accelerated atherosclerosis manifest by increased cardiovascular morbidity and mortality. The high incidence of atherosclerosis is, in part, related to i...

    Authors: Robert G Fassett, Helen Healy, Ritza Driver, Iain K Robertson, Dominic P Geraghty, James E Sharman and Jeff S Coombes
    Citation: BMC Nephrology 2008 9:17
  15. Guidelines for the management of anaemia in patients with chronic kidney disease (CKD) recommend a minimal haemoglobin (Hb) target of 11 g/dL. Recent surveys indicate that this requirement is not met in many p...

    Authors: Claudine M Mathieu, Daniel Teta, Nathalie Lötscher, Dela Golshayan, Luca Gabutti, Denes Kiss, Pierre-Yves Martin and Michel Burnier
    Citation: BMC Nephrology 2008 9:16
  16. In hemodialysis, extracorporeal blood flow (Qb) recommendation is 300–500 mL/min. To achieve the best Qb, we based our prescription on dynamic arterial line pressure (DALP).

    Authors: Franklin G Mora-Bravo, Alfonso Mariscal, Juan P Herrera–Felix, Salvador Magaña, Guadalupe De-La-Cruz, Nelly Flores, Laura Rosales, Martha Franco and Héctor Pérez-Grovas
    Citation: BMC Nephrology 2008 9:15
  17. The study examines differences regarding quality of life (QoL), mental health and illness beliefs between in-centre haemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD/PD) patients. Differen...

    Authors: M Ginieri-Coccossis, P Theofilou, C Synodinou, V Tomaras and C Soldatos
    Citation: BMC Nephrology 2008 9:14
  18. Focal and segmental glomerulosclerosis (FSGS) is the most common histologic pattern of renal injury seen in adults with idiopathic proteinuria. Homozygous or compound heterozygous mutations in the podocin gene NP...

    Authors: Stephen J Tonna, Alexander Needham, Krishna Polu, Andrea Uscinski, Gerald B Appel, Ronald J Falk, Avi Katz, Salah Al-Waheeb, Bernard S Kaplan, George Jerums, Judy Savige, Jennifer Harmon, Kang Zhang, Gary C Curhan and Martin R Pollak
    Citation: BMC Nephrology 2008 9:13
  19. Familial hypomagnesaemia with hypercalciuria and nephrocalcinosis (FHHNC) is an autosomal recessive disorder of renal calcium and magnesium wasting frequently complicated by progressive chronic renal failure i...

    Authors: Geeta Hampson, Martin A Konrad and John Scoble
    Citation: BMC Nephrology 2008 9:12
  20. Monoclonal free light chains (FLCs) frequently cause rapidly progressive renal failure in patients with multiple myeloma. Immunoassays which provide quantitative measurement of FLCs in serum, have now been ado...

    Authors: Colin A Hutchison, Tim Plant, Mark Drayson, Paul Cockwell, Melpomeni Kountouri, Kolitha Basnayake, Stephen Harding, Arthur R Bradwell and Graham Mead
    Citation: BMC Nephrology 2008 9:11
  21. Autosomal Dominant Polycystic Kidney Disease (ADPKD) is characterized by the formation of multiple fluid-filled cysts that destroy the kidney architecture resulting in end-stage renal failure. Mutations in genes

    Authors: Kyriacos N Felekkis, Panayiota Koupepidou, Evdokia Kastanos, Ralph Witzgall, Chang-Xi Bai, Li Li, Leonidas Tsiokas, Norbert Gretz and Constantinos Deltas
    Citation: BMC Nephrology 2008 9:10
  22. Prior studies using creatinine-based estimated glomerular filtration rate (eGFR) have found limited associations between kidney function and markers of inflammation. Using eGFR and cystatin C, a novel marker o...

    Authors: Christopher Keller, Ronit Katz, Mary Cushman, Linda F Fried and Michael Shlipak
    Citation: BMC Nephrology 2008 9:9
  23. The main hypothesis of this study is that Oxpentifylline administration will effectively treat erythropoietin- or darbepoietin-resistant anaemia in chronic kidney disease patients.

    Authors: David Wayne Johnson, Carmel Mary Hawley, Brenda Rosser, Elaine Beller, Charles Thompson, Robert G Fassett, Paolo Ferrari, Stephen MacDonald, Eugenie Pedagogos and Alan Cass
    Citation: BMC Nephrology 2008 9:8
  24. Selenoproteins contain selenocysteine (Sec), commonly considered the 21st genetically encoded amino acid. Many selenoproteins, such as the glutathione peroxidases and thioredoxin reductases, protect cells against...

    Authors: Marsha N Blauwkamp, Jingcheng Yu, MaryLee A Schin, Kathleen A Burke, Marla J Berry, Bradley A Carlson, Frank C Brosius III and Ronald J Koenig
    Citation: BMC Nephrology 2008 9:7
  25. Concern lingers that dialysis therapy at for-profit (versus not-for-profit) hemodialysis facilities in the United States may be associated with higher mortality, even though 4 of every 5 contemporary dialysis ...

    Authors: Robert N Foley, Qiao Fan, Jiannong Liu, David T Gilbertson, Eric D Weinhandl, Shu-Cheng Chen and Allan J Collins
    Citation: BMC Nephrology 2008 9:6
  26. Administrative claims are a rich source of information for epidemiological and health services research; however, the ability to accurately capture specific diseases or complications using claims data has been...

    Authors: Alisa M Shea, Lesley H Curtis, Lynda A Szczech and Kevin A Schulman
    Citation: BMC Nephrology 2008 9:5
  27. There is evidence that dyslipidemia is associated with chronic kidney disease (CKD). Experimental studies have established that lipids are damaging to the kidney and animal intervention studies show statins at...

    Authors: Robert G Fassett, Madeleine J Ball, Iain K Robertson, Dominic P Geraghty and Jeff S Coombes
    Citation: BMC Nephrology 2008 9:4
  28. Cardiovascular events are the leading cause of death in end stage renal disease (ESRD). Adherence to phosphate binding medication plays a vital role in reducing serum phosphorus and associated cardiovascular r...

    Authors: Christina Karamanidou, Jane Clatworthy, John Weinman and Rob Horne
    Citation: BMC Nephrology 2008 9:2
  29. An ad hoc peer-review committee was jointly appointed by Drug Authorities and Industry in Germany, Austria and Switzerland in 1999/2000 to review the evidence for a causal relation between phenacetin-free anal...

    Authors: Fokke J van der Woude, Lothar AJ Heinemann, Helmut Graf, Michael Lewis, Sabine Moehner, Anita Assmann and Doerthe Kühl-Habich
    Citation: BMC Nephrology 2007 8:15
  30. The aim of this study is to evaluate the association between acute serum creatinine changes in acute renal failure (ARF), before specialized treatment begins, and in-hospital mortality, recovery of renal funct...

    Authors: Jose Ramon Perez-Valdivieso, Maira Bes-Rastrollo, Pablo Monedero, Jokin de Irala and Francisco Javier Lavilla
    Citation: BMC Nephrology 2007 8:14
  31. Currently there is no effective treatment available to retard cyst growth and to prevent the progression to end-stage renal failure in patients with autosomal dominant polycystic kidney disease (ADPKD). Eviden...

    Authors: Andreas L Serra, Andreas D Kistler, Diane Poster, Marian Struker, Rudolf P Wüthrich, Dominik Weishaupt and Frank Tschirch
    Citation: BMC Nephrology 2007 8:13
  32. Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disease with few treatment options other than renal replacement therapy. p21, a cyclin kinase inhibitor which has pleiotropic effects on...

    Authors: Jin-Young Park, William E Schutzer, Jessie N Lindsley, Susan P Bagby, Terry T Oyama, Sharon Anderson and Robert H Weiss
    Citation: BMC Nephrology 2007 8:12
  33. Idiopathic membranous nephropathy (IMN) is one of the most common causes of primary nephrotic syndrome in adults. However, it is a relatively rare entity in the pediatric population and there is a paucity of d...

    Authors: Ashton Chen, Rachel Frank, Suzanne Vento, Virginia Crosby, Manju Chandra, Bernard Gauthier, Elsa Valderrama and Howard Trachtman
    Citation: BMC Nephrology 2007 8:11
  34. Systemic hypertension often accompanies chronic renal failure and can accelerate its progression to end-stage renal disease (ESRD). Adjunctive moxonidine appeared to have benefits versus adjunctive nitrendipin...

    Authors: Kavi J Littlewood, Wolfgang Greiner, Dominique Baum and York Zoellner
    Citation: BMC Nephrology 2007 8:9
  35. Fibrillary glomerulonephritis is a rare cause of progressive renal dysfunction, often leading to the need for dialysis within a few years. The role of immunosuppressive treatment is still uncertain although th...

    Authors: Muhammad M Javaid, Helen Denley and Senyo Tagboto
    Citation: BMC Nephrology 2007 8:7
  36. Imatinib is a tyrosine-kinase inhibitor; for which there is limited information regarding its effects on AIDS Kaposi's sarcoma and none in patients with transplant-associated Kaposi's sarcoma. Sirolimus, an im...

    Authors: Patricia Volkow, Juan W Zinser and Ricardo Correa-Rotter
    Citation: BMC Nephrology 2007 8:6
  37. Thrombocytopenia and absent radius syndrome (TAR) is a rare genetic disorder. It is an autosomal recessive disorder characterised by radial aplasia and thrombocytopenia that may have additional anomalies. We r...

    Authors: Riaz Ahmad
    Citation: BMC Nephrology 2007 8:5
  38. It is uncertain whether patients with renal vascular disease will have renal or mortality benefit from re-establishing renal blood flow with renal revascularization procedures. The RAVE study will compare rena...

    Authors: Sheldon W Tobe, M Atri, N Perkins, R Pugash and Chaim M Bell
    Citation: BMC Nephrology 2007 8:4
  39. Mercuric chloride (HgCl2) induces an autoimmune nephritis in the Brown Norway (BN) rats characterized by anti-glomerular basement membrane antibodies (anti-GBM Ab) deposition, proteinuria and a severe interstitia...

    Authors: María M Escribese, Elisa Conde, Ana Martín, David Sáenz-Morales, David Sancho, Guillermo Pérez de Lema, Javier Lucio-Cazaña, Francisco Sánchez-Madrid, María L García-Bermejo and Francisco M Mampaso
    Citation: BMC Nephrology 2007 8:3
  40. The prevalences and risk factors of microalbuminuria are not full described among black African diabetic patients. This study aimed at determining the prevalence of microalbuminuria among African diabetes pati...

    Authors: Janet Joy Kachuchuru Lutale, Hrafnkell Thordarson, Zulfiqarali Gulam Abbas and Kåre Vetvik
    Citation: BMC Nephrology 2007 8:2
  41. This study used a cross sectional survey to examine the effect of gender, age, and geographical location on the population prevalence of renal replacement therapy (RRT) provision in Wales.

    Authors: Hugo C van Woerden, Jane Wilkinson, Martin Heaven and Jason Merrifield
    Citation: BMC Nephrology 2007 8:1
  42. Hornet stings are generally associated with local and occasionally anaphylactic reactions. Rarely systemic complications like acute renal failure can occur following multiple stings. Renal failure is usually d...

    Authors: Aman Sharma, Ajay Wanchu, V Mahesha, V Sakhuja, Pradeep Bambery and Surjit Singh
    Citation: BMC Nephrology 2006 7:18
  43. Small vessel vasculitides are known to follow a devastating course towards end-stage renal disease, unless treated with immunosuppressive regiments. We investigated the value of clinical, histological and immu...

    Authors: Efstathios Alexopoulos, Lazaros Gionanlis, Ekaterini Papayianni, Elizabeth Kokolina, Maria Leontsini and Dimitrios Memmos
    Citation: BMC Nephrology 2006 7:16
  44. The Renin-Angiotensin system (RAS) is a key regulator of both blood pressure and kidney functions and their interaction. In such a situation, genetic variability in the genes of different components of RAS is ...

    Authors: Gaurav Tripathi, Poonam Dharmani, Faisal Khan, RK Sharma, Vinod Pandirikkal Baburajan and Suraksha Agrawal
    Citation: BMC Nephrology 2006 7:15

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