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  1. Uncertainty exists regarding the optimal method to estimate glomerular filtration rate (GFR) for disease detection and monitoring. Widely used GFR estimates have not been validated in British ethnic minority p...

    Authors: Edmund J Lamb, Elizabeth A Brettell, Paul Cockwell, Neil Dalton, Jon J Deeks, Kevin Harris, Tracy Higgins, Philip A Kalra, Kamlesh Khunti, Fiona Loud, Ryan S Ottridge, Claire C Sharpe, Alice J Sitch, Paul E Stevens, Andrew J Sutton and Maarten W Taal
    Citation: BMC Nephrology 2014 15:13
    Content type: Study protocol Published on:

  2. Posterior reversible encephalopathy syndrome (PRES) is a clinical and radiological entity characterized clinically by headache, altered mental status, seizures, visual disturbances, and other focal neurologica...

    Authors: Brett R Graham and George B Pylypchuk
    Citation: BMC Nephrology 2014 15:10
    Content type: Case report Published on:

  3. Detecting impaired glomerular filtration rate (GFR) is important in intensive care units (ICU) in order to diagnose acute kidney injuries and adjust the dose of renally excreted drugs. Whether serum Cystatin C...

    Authors: Pierre Delanaye, Etienne Cavalier, Jérôme Morel, Manolie Mehdi, Nicolas Maillard, Guillaume Claisse, Bernard Lambermont, Bernard E Dubois, Pierre Damas, Jean-Marie Krzesinski, Alexandre Lautrette and Christophe Mariat
    Citation: BMC Nephrology 2014 15:9
    Content type: Research article Published on:

  4. Repeated exposure to peritoneal dialysis (PD) solutions contributes to cumulative intraperitoneal inflammation and peritoneal injury. The present study aimed to explore the capacity of dialysate interleukin-6(...

    Authors: Yeoungjee Cho, David W Johnson, David A Vesey, Carmel M Hawley, Elaine M Pascoe, Margaret Clarke and Nicholas Topley
    Citation: BMC Nephrology 2014 15:8
    Content type: Research article Published on:

  6. Chronic musculoskeletal (MS) pain is common in patients with chronic kidney disease (CKD) undergoing haemodialysis. However, epidemiological data for chronic MS pain and factors associated with chronic MS pain...

    Authors: Heng-Jung Hsu, Chiung-Hui Yen, Kuang-Hung Hsu, I-Wen Wu, Chin-Chan Lee, Ming-Jui Hung, Chiao-Yin Sun, Chia-Chi Chou, Yung-Chih Chen, Ming-Fang Hsieh, Chun-Yu Chen, Chiao-Ying Hsu, Chi-Jen Tsai and Mai-Szu Wu
    Citation: BMC Nephrology 2014 15:6
    Content type: Research article Published on:

  7. Haemolytic-uremic syndrome (HUS) is a severe, life-threatening disease with symptoms such as haemolytic anaemia, renal failure, and a low platelet count. Possible aetiology includes bacterial infections, medic...

    Authors: Yi-Che Lee, Jyh-Seng Wang, Jeng-Chuan Shiang, Ming-Kai Tsai, Kai-Tai Deng, Min-Yu Chang, Hsi-Hao Wang, Li-Chun Ho, Yi-Ting Chen and Shih-Yuan Hung
    Citation: BMC Nephrology 2014 15:5
    Content type: Case report Published on:

  8. Little is known about the effects of intermittent hemodialysis on microcirculatory perfusion. The aim of this study is to assess the effects of hemodialysis on microvascular perfusion using transcutaneous oxym...

    Authors: Ygal Benhamou, Loic Begarin, Nathalie David, Nicole Cailleux, Catherine Bessin, Herve Lévesque and Stephane Edet
    Citation: BMC Nephrology 2014 15:4
    Content type: Research article Published on:

  9. Nephrotic syndrome (NS) is pathological condition characterized by heavy proteinuria. Our study investigates hypothesis that change in cell proliferation of proximal tubules influences primary cilia structure ...

    Authors: Marijan Saraga, Katarina Vukojević, Vjekoslav Krželj, Zvonimir Puretić, Ivana Bočina, Merica Glavina Durdov, Stefanie Weber, Bernd Dworniczak, Danica Galešić Ljubanović and Mirna Saraga-Babić
    Citation: BMC Nephrology 2014 15:3
    Content type: Research article Published on:

  10. Contrast-induced nephropathy (CIN) is a common cause of acute renal failure in hospital patients. To prevent CIN, identification and hydration of high-risk patients is important. Prevention of CIN by hydration...

    Authors: Janneke Schilp, Carolien de Blok, Maaike Langelaan, Peter Spreeuwenberg and Cordula Wagner
    Citation: BMC Nephrology 2014 15:2
    Content type: Research article Published on:

  11. Acute kidney injury in patients with acute pancreatitis carries a poor prognosis. Hemolytic uremic syndrome (HUS) is characterized by non-immune hemolytic anemia, thrombocytopenia, and renal failure caused by ...

    Authors: Peng Fu, Ai-hong Yuan, Chun-hua Wang, Xin Li and Hai-yang Wu
    Citation: BMC Nephrology 2014 15:1
    Content type: Case report Published on:

  12. High iron load might have a number of toxic effects in the organism. Recently intravenous (iv) iron has been proposed to induce elevation of fibroblast growth factor 23 (FGF23), hypophosphatemia and osteomalac...

    Authors: Eva Gravesen, Jacob Hofman-Bang, Maria L Mace, Ewa Lewin and Klaus Olgaard
    Citation: BMC Nephrology 2013 14:281
    Content type: Research article Published on:

  13. Cardiovascular disease is a major cause of death in patients with stage 4–5 Chronic Kidney disease (CKD, eGFR < 30). There are only limited data on the risk factors predicting these complications in CKD patien...

    Authors: Ahmad Farshid, Rajeev Pathak, Bruce Shadbolt, Leonard Arnolda and Girish Talaulikar
    Citation: BMC Nephrology 2013 14:280
    Content type: Research article Published on:

  14. The Camp COOL programme aims to help young Dutch people with end-stage renal disease (ESRD) develop self-management skills. Fellow patients already treated in adult care (hereafter referred to as ‘buddies’) or...

    Authors: Jane NT Sattoe, Susan Jedeloo and AnneLoes van Staa
    Citation: BMC Nephrology 2013 14:279
    Content type: Research article Published on:

  15. Australians living in rural areas have lower incidence rates of renal replacement therapy and poorer dialysis survival compared with urban dwellers. This study compares peritoneal dialysis (PD) patient charact...

    Authors: Nicholas A Gray, Blair S Grace and Stephen P McDonald
    Citation: BMC Nephrology 2013 14:278
    Content type: Research article Published on:

  16. Anti-glomerular basement membrane (GBM) glomerulonephritis and systemic lupus erythematosus (SLE) are both disorders of the immune system; however, they are known as distinct diseases. Till now no clinical evi...

    Authors: Xiaoxia Liu, Yu Wu, Yuan Yang, Jue Wang, Ye Tao, Ping Fu and Zhangxue Hu
    Citation: BMC Nephrology 2013 14:277
    Content type: Case report Published on:

  17. Hyponatremia is associated with increased mortality in chronic kidney disease with and without end-stage renal disease (ESRD). Increasing evidence suggests that hyponatremia is not only a marker of severe unde...

    Authors: Shintaro Mandai, Michio Kuwahara, Yuri Kasagi, Keita Kusaka, Tomomi Tanaka, Satomi Shikuma, Wataru Akita and Sei Sasaki
    Citation: BMC Nephrology 2013 14:276
    Content type: Research article Published on:

  18. Dyspepsia is common among end-stage renal disease (ESRD) patients and its association with delayed gastric emptying is not well established. We assessed the association of dyspepsia with gastric emptying time ...

    Authors: Luiz Derwal Salles Junior, Paulo Roberto Santos, Armênio Aguiar dos Santos and Marcellus Henrique Loiola Ponte de Souza
    Citation: BMC Nephrology 2013 14:275
    Content type: Research article Published on:

  19. Dendritic cells (DC) are professional antigen-presenting cells in the immune system. They patrol the blood as circulating dendritic cell precursors (DCP). Decreased blood DCP count has been shown to be related...

    Authors: Katharina Paul, Daniel Kretzschmar, Atilla Yilmaz, Barbara Bärthlein, Stephanie Titze, Gunter Wolf and Martin Busch
    Citation: BMC Nephrology 2013 14:274
    Content type: Research article Published on:

  20. The predictive value of acute kidney injury (AKI) urinary biomarkers may depend on the time interval following tubular injury, thereby explaining in part the heterogeneous performance of these markers that has...

    Authors: Hilde RH de Geus, Gijs Fortrie, Michiel GH Betjes, Ron HN van Schaik and AB Johan Groeneveld
    Citation: BMC Nephrology 2013 14:273
    Content type: Research article Published on:

  21. Focal segmental glomerulosclerosis-like lesions have been proposed to be predictive factors for IgA nephropathy. This single center, retrospective cohort study was designed to clarify which clinical and pathol...

    Authors: Kunihiro Maeda, Shogo Kikuchi, Naoto Miura, Keisuke Suzuki, Wataru Kitagawa, Hiroyuki Morita, Shogo Banno and Hirokazu Imai
    Citation: BMC Nephrology 2013 14:272
    Content type: Research article Published on:

  22. Estimation of Glomerular Filtration Rate (GFR) by equations such as Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) or Modification of Diet in Renal Disease (MDRD) is usually expressed as a Body Su...

    Authors: Belén Redal-Baigorri, Knud Rasmussen and James Goya Heaf
    Citation: BMC Nephrology 2013 14:271
    Content type: Research article Published on:

  23. Contrast-induced acute kidney injury (CI-AKI) particularly in high risk patients with chronic kidney disease (CKD), increases morbidity and mortality. Neutrophil gelatinase-associated lipocalin (NGAL) is a pro...

    Authors: Adis Tasanarong, Pisit Hutayanon and Dilok Piyayotai
    Citation: BMC Nephrology 2013 14:270
    Content type: Research article Published on:

  24. The purpose of this study was to evaluate the combined effect of different pre-hemodialysis (HD) serum sodium (S[Na]) and potassium (S[K]) concentrations on the long-term prognosis of HD patients.

    Authors: Jyh-Chang Hwang, Ming-Yan Jiang and Charn-Ting Wang
    Citation: BMC Nephrology 2013 14:269
    Content type: Research article Published on:

  25. Creatinine secretion, as quantified by the ratio of creatinine clearance (CrCl) to glomerular filtration rate (GFR), may introduce another source of error when using serum creatinine concentration to estimate ...

    Authors: Yen-chung Lin, Nisha Bansal, Eric Vittinghoff, Alan S Go and Chi-yuan Hsu
    Citation: BMC Nephrology 2013 14:268
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Nephrology 2014 15:85

  26. Renal dysfunction is associated with a variety of cardiac alterations including left ventricular (LV) hypertrophy, LV dilation, and reduction in systolic and diastolic function. It is common and associated wit...

    Authors: Morten Schou, Jesper Kjaergaard, Christian Torp-Pedersen, Christian Hassager, Finn Gustafsson, Dilek Akkan, Jacob E Moller and Lars Kober
    Citation: BMC Nephrology 2013 14:267
    Content type: Research article Published on:

  27. Chronic fluid overload is associated with higher mortality in dialysis patients; however, the link with cardiovascular morbidity has not formally been established and may be influenced by subclinical inflammat...

    Authors: Marlies Antlanger, Manfred Hecking, Michael Haidinger, Johannes Werzowa, Johannes J Kovarik, Gernot Paul, Manfred Eigner, Diana Bonderman, Walter H Hörl and Marcus D Säemann
    Citation: BMC Nephrology 2013 14:266
    Content type: Research article Published on:

  28. Equations to estimate GFR have not been well validated in the elderly and may misclassify persons with chronic kidney disease (CKD). We measured GFR and compared the performance of the Modification of Diet in ...

    Authors: Marcelo B Lopes, Lara Q Araújo, Michelle T Passos, Sonia K Nishida, Gianna M Kirsztajn, Maysa S Cendoroglo and Ricardo C Sesso
    Citation: BMC Nephrology 2013 14:265
    Content type: Research article Published on:

  29. There have been major changes in the management of anemia in US hemodialysis patients in recent years. We sought to determine the influence of clinical trial results, safety regulations, and changes in reimbur...

    Authors: Dana C Miskulin, Jing Zhou, Navdeep Tangri, Karen Bandeen-Roche, Courtney Cook, Patti L Ephraim, Deidra C Crews, Julia J Scialla, Stephen M Sozio, Tariq Shafi, Bernard G Jaar and L Ebony Boulware
    Citation: BMC Nephrology 2013 14:264
    Content type: Research article Published on:

  30. Clinical outcomes of dialysis patients are variable, and improved knowledge of prognosis would inform decisions regarding patient management. We assessed the value of simple, chest X-ray derived measures of ca...

    Authors: Ethan Bohn, Navdeep Tangri, Brent Gali, Blair Henderson, Manish M Sood, Paul Komenda and Claudio Rigatto
    Citation: BMC Nephrology 2013 14:263
    Content type: Research article Published on:

  31. The current treatment options for idiopathic membranous nephropathy (IMN) carry significant toxicity. In this prospective, observational pilot study, we used single time infusion of bone marrow derived autolog...

    Authors: Upal Sengupta, Vinod Kumar, Ashok K Yadav, Neelam Marwaha, Harbir S Kohli, Vinay Sakhuja and Vivekanand Jha
    Citation: BMC Nephrology 2013 14:262
    Content type: Research article Published on:

  32. Among kidney transplant recipients, non-adherence with immunosuppressive medications frequently precedes allograft loss. We sought to determine the prevalence and correlates of medication non-adherence among k...

    Authors: Francis L Weng, Sheenu Chandwani, Karen M Kurtyka, Christopher Zacker, Marie A Chisholm-Burns and Kitaw Demissie
    Citation: BMC Nephrology 2013 14:261
    Content type: Research article Published on:

  33. The mechanism for the development of thrombotic microangiopathy (TMA) during sepsis has only been partially elucidated. TMA is recognized as a disease caused by various factors, and may be involved in the emer...

    Authors: Yusuke Sakamaki, Konosuke Konishi, Koichi Hayashi, Akinori Hashiguchi, Matsuhiko Hayashi, Eiji Kubota, Takao Saruta and Hiroshi Itoh
    Citation: BMC Nephrology 2013 14:260
    Content type: Case report Published on:

  34. Protein-energy wasting (PEW) is common in hemodialysis patients and is a powerful predictor of morbidity and mortality. Although much progress has been made in recent years in identifying the causes and pathog...

    Authors: Justine Magnard, Thibault Deschamps, Christophe Cornu, Anne Paris and Dan Hristea
    Citation: BMC Nephrology 2013 14:259
    Content type: Study protocol Published on:

  35. There is no single model available to predict the long term survival for patients starting renal replacement therapy (RRT). The available models either predict survival on dialysis until transplantation, survi...

    Authors: Aline C Hemke, Martin BA Heemskerk, Merel van Diepen, Willem Weimar, Friedo W Dekker and Andries J Hoitsma
    Citation: BMC Nephrology 2013 14:258
    Content type: Research article Published on:

  36. The ambulatory arterial stiffness index (AASI) can be used to predict cardiovascular morbidity and mortality in hypertensive patients. However, data on AASI in Chinese patients with chronic kidney disease (CKD...

    Authors: Cheng Wang, Jun Zhang, Cui-Cui Li, Wen-Yu Gong, Xun Liu, Zeng-Chun Ye, Hui Peng and Tan-Qi Lou
    Citation: BMC Nephrology 2013 14:257
    Content type: Research article Published on:

  37. The best treatment option for end-stage renal disease is usually a transplant, preferably a live donor kidney transplant (LDKT). The most effective ways to educate kidney transplant candidates about the risks,...

    Authors: Francis L Weng, Diane R Brown, John D Peipert, Bart Holland and Amy D Waterman
    Citation: BMC Nephrology 2013 14:256
    Content type: Study protocol Published on:

  38. Dialysis disequilibrium syndrome is characterized by neurological symptoms resulting from cerebral edema, which occurs as a consequence of hemodialysis. Dialysis disequilibrium syndrome most often occurs in pa...

    Authors: Yohei Tsuchida, Takuma Takata, Toshihiko Ikarashi, Noriaki Iino, Junichiro J Kazama and Ichiei Narita
    Citation: BMC Nephrology 2013 14:255
    Content type: Case report Published on:

  40. Few population-based studies have examined the relationship between glycemic status and chronic kidney disease (CKD) in China. We examined the prevalence of CKD across categories of glycemia [diagnosed diabete...

    Authors: Yi Zhou, Justin B Echouffo-Tcheugui, Jian-jun Gu, Xiao-nan Ruan, Gen-ming Zhao, Wang-hong Xu, Li-ming Yang, Hong Zhang, Hua Qiu, K M Venkat Narayan and Qiao Sun
    Citation: BMC Nephrology 2013 14:253
    Content type: Research article Published on:

  41. Both vitamin C deficiency and inflammation are prevalent in maintenance hemodialysis (MHD) patients. In this study, we aimed to elucidate the effect of oral vitamin C supplementation on inflammatory status in ...

    Authors: KunYing Zhang, YinHui Li, XuYang Cheng, Li Liu, WenYing Bai, WeiYa Guo, LeiYun Wu and Li Zuo
    Citation: BMC Nephrology 2013 14:252
    Content type: Research article Published on:

  42. The purpose of this study was to determine whether AMPK influences the survival of primary cultures of mouse proximal tubular (MPT) cells subjected to metabolic stress. Previous studies, using an immortalized ...

    Authors: Wilfred Lieberthal, Meiyi Tang, Leiqing Zhang, Benoit Viollet, Vimal Patel and Jerrold S Levine
    Citation: BMC Nephrology 2013 14:251
    Content type: Research article Published on:

  43. The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) estimated glomerular filtration rate (eGFR) has been widely integrated into clinical practice. Although useful in screening for CKD, its’ applica...

    Authors: Andrew A Udy, Fraser JA Morton, Sallyanne Nguyen-Pham, Paul Jarrett, Melissa Lassig-Smith, Janine Stuart, Rachel Dunlop, Therese Starr, Robert J Boots and Jeffrey Lipman
    Citation: BMC Nephrology 2013 14:250
    Content type: Research article Published on:

  44. Several observational studies have evaluated the effect of a single exposure window with blood pressure (BP) medications on outcomes in incident dialysis patients, but whether BP medication prescription patter...

    Authors: Wendy L St Peter, Stephen M Sozio, Tariq Shafi, Patti L Ephraim, Jason Luly, Aidan McDermott, Karen Bandeen-Roche, Klemens B Meyer, Deidra C Crews, Julia J Scialla, Dana C Miskulin, Navdeep Tangri, Bernard G Jaar, Wieneke M Michels, Albert W Wu and L Ebony Boulware
    Citation: BMC Nephrology 2013 14:249
    Content type: Research article Published on:

  46. Elevated cardiac troponin I (TnI) levels are associated with all-cause mortality in stable hemodialysis patients. Their relationship to cardiac-specific death has been inconsistent, and the reason for their el...

    Authors: Ahsan Alam, Andrea Palumbo, Istvan Mucsi, Paul E Barré and Allan D Sniderman
    Citation: BMC Nephrology 2013 14:247
    Content type: Research article Published on:

  47. Low 24-hour urine volume (24UV) may be a significant risk factor for decline in kidney function. We therefore aimed to study associated markers and possible determinants of 24UV in a sample of the Swiss popula...

    Authors: Tobias Schoen, Jonas Blum, Fred Paccaud, Michel Burnier, Murielle Bochud and David Conen
    Citation: BMC Nephrology 2013 14:246
    Content type: Research article Published on:

  48. Placental growth factor (PlGF), pregnancy-associated plasma protein-A (PAPP-A), soluble receptor for advanced glycation end products (sRAGE), extracellular newly identified receptor for RAGE binding protein (E...

    Authors: Oskar Zakiyanov, Vitezslav Kriha, Jan Vachek, Tomas Zima, Vladimir Tesar and Marta Kalousova
    Citation: BMC Nephrology 2013 14:245
    Content type: Research article Published on:

  50. Hemoglobin (Hb) variability is a common occurrence in hemodialysis patients treated with erythropoiesis-stimulating agents. High amplitude fluctuations have been associated with greater risk of morbidity and m...

    Authors: Jacques B Rottembourg, Floride Kpade, Fadia Tebibel, Aurélie Dansaert and Gaelle Chenuc
    Citation: BMC Nephrology 2013 14:243
    Content type: Research article Published on:
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BMC Nephrology

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