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  1. The renal distal nephron plays an important role in the maintenance of sodium balance, extra cellular volume and blood pressure. The degree of water transport, via aquaporin2 water channels (AQP2), and sodium ...

    Authors: Janni M Jensen, Frank H Mose, Jesper N Bech, Soren Nielsen and Erling B Pedersen
    Citation: BMC Nephrology 2013 14:202
    Content type: Research article Published on:

  2. Among African-Americans adults, arterial hypertension is both more prevalent and associated with more complications than among white adults. Hypertension is also epidemic among black adults in sub-Saharan Afri...

    Authors: Robert N Peck, Luke R Smart, Rita Beier, Anthony C Liwa, Heiner Grosskurth, Daniel W Fitzgerald and Bernhard MW Schmidt
    Citation: BMC Nephrology 2013 14:201
    Content type: Research article Published on:

  3. Responsiveness to erythropoiesis-stimulating agents (ESAs) varies widely among dialysis patients. ESA resistance has been associated with mortality in hemodialysis (HD) patients, but in peritoneal dialysis (PD...

    Authors: Marit M Suttorp, Tiny Hoekstra, Joris I Rotmans, Ilka Ott, Moshe Mittelman, Raymond T Krediet and Friedo W Dekker
    Citation: BMC Nephrology 2013 14:200
    Content type: Research article Published on:

  4. Vitamin D insufficiency correlates with mortality risk among patients with chronic kidney disease (CKD). The survival benefits of active vitamin D treatment have been assessed in patients with CKD not requirin...

    Authors: Zhenfeng Zheng, Huilan Shi, Junya Jia, Dong Li and Shan Lin
    Citation: BMC Nephrology 2013 14:199
    Content type: Research article Published on:

  5. Chronic kidney disease (CKD) is a known risk factor for cardiovascular events and all-cause mortality. We investigate the relationship between CKD stage, proteinuria, hypertension and these adverse outcomes in...

    Authors: Andrew P McGovern, Benjamin Rusholme, Simon Jones, Jeremy N van Vlymen, Harshana Liyanage, Hugh Gallagher, Charles RV Tomson, Kamlesh Khunti, Kevin Harris and Simon de Lusignan
    Citation: BMC Nephrology 2013 14:198
    Content type: Research article Published on:

  6. Ten years on from the National Institute of Health and Clinical Excellence’ technology appraisal guideline on haemodialysis in 2002; the clinical community is yet to rise to the challenge of providing home hae...

    Authors: Anuradha Jayanti, Alison J Wearden, Julie Morris, Paul Brenchley, Inger Abma, Steffen Bayer, James Barlow and Sandip Mitra
    Citation: BMC Nephrology 2013 14:197
    Content type: Study protocol Published on:

  8. HUPRA syndrome is a rare mitochondrial disease characterized by hyperuricemia, pulmonary hypertension, renal failure in infancy and alkalosis. This syndrome was previously described in three patients with a ho...

    Authors: Henry Rivera, Elena Martín-Hernández, Aitor Delmiro, María Teresa García-Silva, Pilar Quijada-Fraile, Rafael Muley, Joaquín Arenas, Miguel A Martín and Francisco Martínez-Azorín
    Citation: BMC Nephrology 2013 14:195
    Content type: Case report Published on:

  9. Restless Legs Syndrome is very common in hemodialysis patients however there are no comparative studies assessing the effectiveness of a non-pharmacological treatment to a classical treatment on parameters rel...

    Authors: Christoforos D Giannaki, Giorgos K Sakkas, Christina Karatzaferi, Georgios M Hadjigeorgiou, Eleftherios Lavdas, Theodoros Kyriakides, Yiannis Koutedakis and Ioannis Stefanidis
    Citation: BMC Nephrology 2013 14:194
    Content type: Research article Published on:

  10. Enhanced external counterpulsation (EECP) enhances coronary perfusion and reduces left ventricular afterload. However, the role of EECP on renal function in cardiac patients is unknown. Our aim was to assess r...

    Authors: Prajej Ruangkanchanasetr, Nithi Mahanonda, Ongkarn Raungratanaamporn, Piyanuj Ruckpanich, Chagriya Kitiyakara, Amnart Chaiprasert, Surawat Adirekkiat, Dollapas Punpanich, Somlak Vanavanan, Anchalee Chittamma and Thanom Supaporn
    Citation: BMC Nephrology 2013 14:193
    Content type: Research article Published on:

  11. There is a paucity of information about the views of dialysis nurses towards dialysis modality selection, yet nurses often have the most direct contact time with patients. We conducted a survey to better under...

    Authors: Karthik K Tennankore, Jay Hingwala, Diane Watson, Joanne M Bargman and Christopher T Chan
    Citation: BMC Nephrology 2013 14:192
    Content type: Research article Published on:

  12. In the general population, reported levels of oxidative stress and antioxidant potential seem to vary. The aim of this study was to investigate the levels of oxidant status markers in relation to estimated glo...

    Authors: Yuko Ishizaka, Minoru Yamakado, Akiko Toda, Mizuki Tani and Nobukazu Ishizaka
    Citation: BMC Nephrology 2013 14:191
    Content type: Research article Published on:

  13. Polycystic kidney diseases (PKD) are a group of monogenic disorders that are inherited dominantly (autosomal dominant PKD; ADPKD) or recessively, including, autosomal recessive PKD (ARPKD). A number of recessi...

    Authors: Reza Vazifehmand, Sandro Rossetti, Sassan Saber, Hamid Reza Khorram Khorshid and Peter C Harris
    Citation: BMC Nephrology 2013 14:190
    Content type: Case report Published on:

  14. Haemodialysis patients have an increased prevalence of hypertension and risk of cardiovascular mortality and stroke. Higher dialysate calcium concentrations have been reported to cause both an acute and chroni...

    Authors: Evangelia Charitaki and Andrew Davenport
    Citation: BMC Nephrology 2013 14:189
    Content type: Research article Published on:

  16. Hepatitis C virus (HCV) infection and chronic kidney disease (CKD) have high prevalences in Taiwan and worldwide, but the role of HCV infection in causing CKD remains uncertain. This cohort study aimed to expl...

    Authors: Yi-Chun Chen, Wen-Yen Chiou, Shih-Kai Hung, Yu-Chieh Su and Shang-Jyh Hwang
    Citation: BMC Nephrology 2013 14:187
    Content type: Research article Published on:

  17. Some 7-10% of patients on replacement renal therapy (RRT) are receiving it because of autosomal dominant polycystic kidney disease (ADPKD). The age at initiation of RRT is expected to increase over time.

    Authors: Víctor Martínez, Jordi Comas, Emma Arcos, Joan Manel Díaz, Salomé Muray, Juan Cabezuelo, José Ballarín, Elisabet Ars and Roser Torra
    Citation: BMC Nephrology 2013 14:186
    Content type: Research article Published on:

  18. The aim of this study was to evaluate whether a high baseline level of high-sensitivity C-reactive protein (hs-CRP) or changes in the level predicts the risk of peritonitis in patients on continuous ambulatory...

    Authors: Yu-Jen Su, Shang-Chih Liao, Ben-Chung Cheng, Jyh-Chang Hwang and Jin-Bor Chen
    Citation: BMC Nephrology 2013 14:185
    Content type: Research article Published on:

  19. Chronic kidney disease (CKD) involves a progressive, irreversible loss of kidney function. While early-stage CKD patients may show changes in pulmonary function and lowered exercise tolerance, the role of the ...

    Authors: Ruiter de Souza Faria, Natália Fernandes, Júlio César Moraes Lovisi, Maycon de Moura Reboredo, Murilo Sérgio de Moura Marta, Bruno do Valle Pinheiro and Marcus Gomes Bastos
    Citation: BMC Nephrology 2013 14:184
    Content type: Research article Published on:

  20. The number of adults with diabetes mellitus is increasing worldwide, particularly in Asia and Africa. In sub-Saharan Africa, renal complications of diabetes may go unrecognized due to limited diagnostic resour...

    Authors: Mubarakali N Janmohamed, Samuel E Kalluvya, Andreas Mueller, Rodrick Kabangila, Luke R Smart, Jennifer A Downs and Robert N Peck
    Citation: BMC Nephrology 2013 14:183
    Content type: Research article Published on:

  21. Early referral and management of high-risk chronic kidney disease may prevent or delay the need for dialysis. Automatic eGFR reporting has increased demand for out-patient nephrology consultations and in some ...

    Authors: Michael E Schachter, Alexandra Romann, Ognjenka Djurdev, Adeera Levin and Monica Beaulieu
    Citation: BMC Nephrology 2013 14:182
    Content type: Research article Published on:

  22. Accurate and precise estimates of glomerular filtration rate (GFR) are essential for clinical assessments, and many methods of estimation are available. We developed a radial basis function (RBF) network and a...

    Authors: Xun Liu, Yan-Ru Chen, Ning-shan Li, Cheng Wang, Lin-Sheng Lv, Ming Li, Xiao-Ming Wu and Tan-Qi Lou
    Citation: BMC Nephrology 2013 14:181
    Content type: Research article Published on:

  23. This study describes chronic kidney disease of uncertain aetiology (CKDu), which cannot be attributed to diabetes, hypertension or other known aetiologies, that has emerged in the North Central region of Sri L...

    Authors: Nihal Jayatilake, Shanthi Mendis, Palitha Maheepala and Firdosi R Mehta
    Citation: BMC Nephrology 2013 14:180
    Content type: Research article Published on:

  24. The quality of life (QOL) of patients with autosomal dominant polycystic kidney disease (ADPKD) has not been investigated well. This study was performed to clarify the QOL of patients with ADPKD and to identif...

    Authors: Tatsuya Suwabe, Yoshifumi Ubara, Koki Mise, Masahiro Kawada, Satoshi Hamanoue, Keiichi Sumida, Noriko Hayami, Junichi Hoshino, Rikako Hiramatsu, Masayuki Yamanouchi, Eiko Hasegawa, Naoki Sawa and Kenmei Takaichi
    Citation: BMC Nephrology 2013 14:179
    Content type: Research article Published on:

  25. Hyperphosphatemia, serum phosphorus ≥ 4.4 mg/dL, is associated with increased risk for chronic kidney disease and cardiovascular disease. Previous studies have shown a weak association between dietary phosphor...

    Authors: Janet M Wojcicki
    Citation: BMC Nephrology 2013 14:178
    Content type: Research article Published on:

  26. The number of individuals suffering from chronic kidney disease (CKD) is increasing. Therefore, early identification of modifiable predictors of CKD is highly desirable. Previous studies suggest an association...

    Authors: Gabriele Nagel, Emanuel Zitt, Raphael Peter, Alfonso Pompella, Hans Concin and Karl Lhotta
    Citation: BMC Nephrology 2013 14:177
    Content type: Research article Published on:

  28. The number of elderly people over the age of 65 commencing dialysis in NZ has increased by almost 400% in the past decade. Few data are available about health related outcomes and survival on dialysis in the e...

    Authors: Robert Walker, Sarah Derrett, John Campbell, Mark R Marshall, Andrew Henderson, John Schollum, Sheila Williams and Bronwen McNoe
    Citation: BMC Nephrology 2013 14:175
    Content type: Study protocol Published on:

  29. Warfarin prescribing patterns for hemodialysis patients with atrial fibrillation vary widely amongst nephrologists. This may be due to a paucity of guiding evidence, but also due to concerns of increased risks...

    Authors: Salina Juma, Benjamin KA Thomson, Charmaine E Lok, Catherine M Clase, Peter G Blake and Louise Moist
    Citation: BMC Nephrology 2013 14:174
    Content type: Research article Published on:

  30. Chronic kidney disease (CKD) and coronary artery disease (CAD) are independently associated with increased vascular stiffness. We examined whether renal function contributes to vascular stiffness independently...

    Authors: Sabrina H Rossi, Emily P McQuarrie, William H Miller, Ruth M Mackenzie, Jane A Dymott, María U Moreno, Chiara Taurino, Ashley M Miller, Ulf Neisius, Geoffrey A Berg, Zivile Valuckiene, Jonathan A Hannay, Anna F Dominiczak and Christian Delles
    Citation: BMC Nephrology 2013 14:173
    Content type: Research article Published on:

  31. In March, 2007, a black box warning was issued by the Food and Drug Administration (FDA) to use the lowest possible erythropoiesis-stimulating agents (ESA) doses for treatment of anemia associated with renal d...

    Authors: Mae Thamer, Yi Zhang, Dejian Lai, Onkar Kshirsagar and Dennis Cotter
    Citation: BMC Nephrology 2013 14:172
    Content type: Research article Published on:

  32. Hyponatremia is often observed in patients with Legionella pneumonia. However, other electrolyte abnormalities are uncommon and the mechanism remains to be clarified.

    Authors: Naoko Kinoshita-Katahashi, Hirotaka Fukasawa, Sayaka Ishigaki, Shinsuke Isobe, Shiro Imokawa, Yoshihide Fujigaki and Ryuichi Furuya
    Citation: BMC Nephrology 2013 14:171
    Content type: Case report Published on:

  33. Monitoring of the appearance of left ventricular hypertrophy (LVH) by echocardiography is currently recommended for in the management of children with End-stage renal disease (ESRD). In order to investigate th...

    Authors: Nikki J Schoenmaker, Johanna H van der Lee, Jaap W Groothoff, Gabrielle G van Iperen, Ingrid ME Frohn-Mulder, Ronald B Tanke, Jaap Ottenkamp and Irene M Kuipers
    Citation: BMC Nephrology 2013 14:170
    Content type: Research article Published on:

  34. We established earlier the absolute renal risk (ARR) of dialysis/death (D/D) in primary IgA nephropathy (IgAN) which permitted accurate prospective prediction of final prognosis. This ARR was based on the pote...

    Authors: Hesham Mohey, Blandine Laurent, Christophe Mariat and Francois Berthoux
    Citation: BMC Nephrology 2013 14:169
    Content type: Research article Published on:

  36. Some parenteral iron therapies have been found to be associated with hypophosphatemia. The mechanism of the decrease in serum phosphate is unknown. The aim of this study is to examine the effect of IV ferric c...

    Authors: Merche Prats, Ramon Font, Carmen García, Carmen Cabré, Manel Jariod and Alberto Martinez Vea
    Citation: BMC Nephrology 2013 14:167
    Content type: Research article Published on:

  37. Pseudohypoaldosteronism type II (PHA II), also referred to as Gordon syndrome, is a rare renal tubular disease that is inherited in an autosomal manner. Though mutations in WNK1 and WNK4 partially account for thi...

    Authors: Shoji Tsuji, Miyoko Yamashita, Gen Unishi, Reiko Takewa, Takahisa Kimata, Kiyoshi Isobe, Motoko Chiga, Shinichi Uchida and Kazunari Kaneko
    Citation: BMC Nephrology 2013 14:166
    Content type: Case report Published on:

  38. We previously demonstrated that lovastatin decreases cyst volume and improves kidney function in the Han:SPRD (Cy/+) rat model of ADPKD. Since endothelial dysfunction and inflammatory activity are evident in p...

    Authors: Jelena Klawitter, Iram Zafar, Jost Klawitter, Alexander T Pennington, Jacek Klepacki, Berenice Y Gitomer, Robert W Schrier, Uwe Christians and Charles L Edelstein
    Citation: BMC Nephrology 2013 14:165
    Content type: Research article Published on:

  40. Vitamin D receptor activators reduce albuminuria, and may improve survival in chronic kidney disease (CKD). Animal studies suggest that these pleiotropic effects of vitamin D may be mediated by suppression of ...

    Authors: Thomas Larsen, Frank H Mose, Jesper N Bech and Erling B Pedersen
    Citation: BMC Nephrology 2013 14:163
    Content type: Research article Published on:

  41. Multi-causality and heterogeneity of phenotypes and genotypes characterize complex diseases. In a database with comprehensive collection of phenotypes and genotypes, we compared the performance of common machi...

    Authors: Ross KK Leung, Ying Wang, Ronald CW Ma, Andrea OY Luk, Vincent Lam, Maggie Ng, Wing Yee So, Stephen KW Tsui and Juliana CN Chan
    Citation: BMC Nephrology 2013 14:162
    Content type: Research article Published on:

  42. Recurrent episodes of venous thrombosis have been closely correlated with JAK2 V617F mutation. Upto date, JAK2 gene mutation has not been defined as a prothrombic risk factor in renal transplant recipients. He...

    Authors: Erhan Tatar, Adam Uslu, Ahmet Aykas, Funda Tasli, Ozgur Oztekin and Gulsum Akgun Cagliyan
    Citation: BMC Nephrology 2013 14:161
    Content type: Case report Published on:

  43. Angiomyolipomas are benign tumors of the kidney. Typical angiomyolipomas are usually recognized by identifying fat components before any intervention. On the contrary, solid renal masses without evident fatty ...

    Authors: Chin-Li Chen, Shou-Hung Tang, Sheng-Tang Wu, En Meng, Chih-Wei Tsao, Guang-Huan Sun, Dah-Shyong Yu, Sun-Yran Chang and Tai-Lung Cha
    Citation: BMC Nephrology 2013 14:160
    Content type: Case report Published on:

  44. In renal patients estimation of GFR is routinely done by means of population-based formulae using serum creatinine levels. For GFR determination in the creatinine-blind regions or in cases of reno-hepatic synd...

    Authors: Sabine Zitta, Walter Schrabmair, Gilbert Reibnegger, Andreas Meinitzer, Doris Wagner, Willibald Estelberger and Alexander R Rosenkranz
    Citation: BMC Nephrology 2013 14:159
    Content type: Research article Published on:

  46. In a simulation based on a pharmacokinetic model we demonstrated that increasing the erythropoiesis stimulating agents (ESAs) half-life or shortening their administration interval decreases hemoglobin variabil...

    Authors: Valentina Forni, Giorgia Bianchi, Adam Ogna, Igor Salvadé, Philippe Vuistiner, Michel Burnier and Luca Gabutti
    Citation: BMC Nephrology 2013 14:157
    Content type: Research article Published on:

  47. Thrombotic thrombocytopenic purpura (TTP) is frequently associated with renal abnormalities, but there have been few reports about renal abnormalities in patients with hereditary TTP. In particular, little is ...

    Authors: Koki Mise, Yoshifumi Ubara, Masanori Matsumoto, Keiichi Sumida, Rikako Hiramatsu, Eiko Hasegawa, Masayuki Yamanouchi, Noriko Hayami, Tatsuya Suwabe, Junichi Hoshino, Naoki Sawa, Kenichi Ohashi, Koichi Kokame, Toshiyuki Miyata, Yoshihiro Fujimura and Kenmei Takaichi
    Citation: BMC Nephrology 2013 14:156
    Content type: Case report Published on:

  48. Achieving target levels of laboratory parameters of bone and mineral metabolism in chronic kidney disease (CKD) patients is important but also difficult in those living with end-stage kidney disease. This stud...

    Authors: István Kiss, Zoltán Kiss, Csaba Ambrus, András Szabó, János Szegedi, József Balla, Erzsébet Ladányi, Botond Csiky, Ottó Árkossy, Marietta Török, Sándor Túri and Imre Kulcsár
    Citation: BMC Nephrology 2013 14:155
    Content type: Research article Published on:
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BMC Nephrology

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