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  1. Metabolic complications are associated with clinical outcomes in patients with chronic kidney disease (CKD). These outcomes differ among patients according to the different stages of disease. The prevalence an...

    Authors: I-Wen Wu, Kuang-Hung Hsu, Chin-Chan Lee, Chiao-Yin Sun, Heng-Jung Hsu, Ming-Jui Hung and Mai-Szu Wu
    Citation: BMC Nephrology 2013 14:92
    Content type: Research article Published on:

  2. We describe a case of a fever of unknown etiology that was caused by a caseating tubercle granuloma which produced erythropoietin. To our knowledge, this is the first report of an erythropoietin- producing gra...

    Authors: Minoru Satoh, Hiroshi Ueta, Takehiko Tokura, Tamaki Sasaki and Naoki Kashihara
    Citation: BMC Nephrology 2013 14:91
    Content type: Case report Published on:

  3. People with end-stage kidney disease treated with dialysis experience high rates of premature death that are at least 30-fold that of the general population, and have markedly impaired quality of life. Despite...

    Authors: Giovanni FM Strippoli, Suetonia C Palmer, Marinella Ruospo, Patrizia Natale, Valeria Saglimbene, Jonathan C Craig, Fabio Pellegrini, Massimo Petruzzi, Michele De Benedittis, Pauline Ford, David W Johnson, Eduardo Celia, Ruben Gelfman, Miguel R Leal, Marietta Torok, Paul Stroumza…
    Citation: BMC Nephrology 2013 14:90
    Content type: Study protocol Published on:

  4. There is ongoing controversy concerning optimum anticoagulation and buffering in continuous venovenous haemofiltration (CVVH). Regional anticoagulation with trisodium citrate also acting as a buffer in the rep...

    Authors: Shaikh A Nurmohamed, Borefore P Jallah, Marc G Vervloet, Gul Yldirim, Pieter M ter Wee and AB Johan Groeneveld
    Citation: BMC Nephrology 2013 14:89
    Content type: Research article Published on:

  5. Biochemical markers of altered mineral metabolism have been associated with increased mortality in end stage renal disease patients. Several studies have demonstrated non-linear (U-shaped or J-shaped) associat...

    Authors: Jaime L Natoli, Rob Boer, Brian H Nathanson, Ross M Miller, Silvia Chiroli, William G Goodman and Vasily Belozeroff
    Citation: BMC Nephrology 2013 14:88
    Content type: Research article Published on:

  6. The prevalence of obese and overweight patients has increased dramatically worldwide. Both are common risk factors for chronic kidney disease (CKD) as indicated by a diminished estimated glomerular filtration ...

    Authors: Kathleen Dittmann, Anke Hannemann, Henri Wallaschofski, Rainer Rettig, Sylvia Stracke, Henry Völzke, Matthias Nauck and Nele Friedrich
    Citation: BMC Nephrology 2013 14:87
    Content type: Research article Published on:

  7. Chronic kidney disease (CKD) is an emerging public health problem worldwide. Previous studies have shown an association between blood pressure (BP) and CKD. However, it is not clear if there are ethnic differe...

    Authors: Charumathi Sabanayagam, Boon Wee Teo, E Shyong Tai, Tazeen H Jafar and Tien Yin Wong
    Citation: BMC Nephrology 2013 14:86
    Content type: Research article Published on:

  8. Fibroblast growth factor 23 (FGF23) is the earliest marker of disturbed mineral metabolism as renal function decreases. Its serum levels are associated with mortality in dialysis patients, persons with chronic...

    Authors: Per-Anton Westerberg, Åsa Tivesten, Magnus K Karlsson, Dan Mellström, Eric Orwoll, Claes Ohlsson, Tobias E Larsson, Torbjörn Linde and Östen Ljunggren
    Citation: BMC Nephrology 2013 14:85
    Content type: Research article Published on:

  9. Renal cell carcinoma (RCC) may involve both kidneys. When bilateral nephrectomy is necessary renal replacement therapy is mandatory. Treating such patients with sequential therapy based on cytokines, antiangio...

    Authors: John Syrios, Georgios Kechagias and Nicolas Tsavaris
    Citation: BMC Nephrology 2013 14:84
    Content type: Case report Published on:

  10. Psychosocial factors including depression, anxiety and lower social support are common in patients with chronic kidney disease (CKD). However the influence of these potentially modifiable risk factors on morbi...

    Authors: Charlotte M McKercher, Alison J Venn, Leigh Blizzard, Mark R Nelson, Andrew J Palmer, Michael A Ashby, Jennifer L Scott and Matthew D Jose
    Citation: BMC Nephrology 2013 14:83
    Content type: Research article Published on:

  11. IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide, leading to renal failure in 15% to 40% of cases. IgAN is diagnosed by renal biopsy, an invasive method that is not risk-free. We ...

    Authors: Fredzzia Graterol, Maribel Navarro-Muñoz, Meritxell Ibernon, Dolores López, Maria-Isabel Troya, Vanessa Pérez, Josep Bonet and Ramón Romero
    Citation: BMC Nephrology 2013 14:82
    Content type: Research article Published on:

  12. Large, population-based administrative healthcare databases can be used to identify patients with chronic kidney disease (CKD) when serum creatinine laboratory results are unavailable. We examined the validity...

    Authors: Jamie L Fleet, Stephanie N Dixon, Salimah Z Shariff, Robert R Quinn, Danielle M Nash, Ziv Harel and Amit X Garg
    Citation: BMC Nephrology 2013 14:81
    Content type: Research article Published on:

  13. A marked reduction in serum levels of bioactive insulin-like growth factor-I (IGF-I) has been observed in fasting hemodialysis (HD) patients during a 4-h HD session. The aim of the present study was to investi...

    Authors: Mark Reinhard, Jan Frystyk, Bente Jespersen, Mette Bjerre, Jens S Christiansen, Allan Flyvbjerg and Per Ivarsen
    Citation: BMC Nephrology 2013 14:80
    Content type: Research article Published on:

  14. There are only a few risk factors known for primary patency loss in patients with an arteriovenous graft or fistula. Furthermore, a limited number of studies have investigated the association between arteriove...

    Authors: Gürbey Ocak, Joris I Rotmans, Carla Y Vossen, Frits R Rosendaal, Raymond T Krediet, Elisabeth W Boeschoten, Friedo W Dekker and Marion Verduijn
    Citation: BMC Nephrology 2013 14:79
    Content type: Research article Published on:

  15. Chronic kidney disease (CKD) is a progressive disease that causes a permanent impairment of renal function and premature mortality. The associated prognosis may result in serious psychological distress to the ...

    Authors: Hsin-Hung Chiang, Hanoch Livneh, Mei-Ling Yen, Tsai-Chung Li and Tzung-Yi Tsai
    Citation: BMC Nephrology 2013 14:78
    Content type: Research article Published on:

  16. Chronic kidney disease (CKD) is known to expose the patient to a high risk of death due to cardiovascular and infective causes. In parallel, septic shock is a major challenge for cardiovascular and immune syst...

    Authors: Julien Maizel, Romain Deransy, Benedicte Dehedin, Edouard Secq, Elie Zogheib, Elisabeth Lewandowski, Chritstophe Tribouilloy, Ziad A Massy, Gabriel Choukroun and Michel Slama
    Citation: BMC Nephrology 2013 14:77
    Content type: Research article Published on:

  17. Renal replacement therapy may have a favorable effect on diastolic left ventricular function, but it is not clear whether hemodiafiltration is superior to hemodialysis in this field. Nitric oxide (NO) and asym...

    Authors: Árpád Czifra, Alida Páll, Julianna Kulcsár, Kitti Barta, Attila Kertész, György Paragh, István Lőrincz, Zoltán Jenei, Anupam Agarwal, Abolfazl Zarjou, József Balla and Zoltán Szabó
    Citation: BMC Nephrology 2013 14:76
    Content type: Research article Published on:

  18. Population-based data on the burden of chronic kidney disease (CKD) in sub-Saharan Africa is still very limited. We assessed the prevalence and determinants of CKD, and evaluated the concordance of commonly ad...

    Authors: Tandi E Matsha, Yandiswa Y Yako, Megan A Rensburg, Mogamat S Hassan, Andre P Kengne and Rajiv T Erasmus
    Citation: BMC Nephrology 2013 14:75
    Content type: Research article Published on:

  21. Myeloperoxidase anti-neutrophil cytoplasmic antibody-associated glomerulonephritis (MPO-ANCA-GN) and concurrent membranous nephropathy (MN) are very rare combination. Their causal relationship has been suggest...

    Authors: Michiko Shimada, Takeshi Fujita, Norio Nakamura, Ikuyo Narita, Yuko Shimaya, Reiichi Murakami, Hideaki Yamabe, Hiroshi Osawa and Ken Okumura
    Citation: BMC Nephrology 2013 14:73
    Content type: Case report Published on:

  22. During haemodialysis (HD) treatment, increase of platelet (PLT) activation and induction of procoagulant activity is demonstrated. Although the role of the endothelium and its direct interaction with coagulati...

    Authors: Marianne Schoorl, Margreet Schoorl, Menso J Nubé and Piet CM Bartels
    Citation: BMC Nephrology 2013 14:72
    Content type: Research article Published on:

  23. The Chimney graft (CG) procedure is one of the novel modification techniques of the endovascular aneurysm repair (EVAR) surgery to treat suprarenal and juxtarenal abdominal aortic aneurysms. Other indications ...

    Authors: Amir Gal-Oz, Yehuda G Wolf, Galia Rosen, Haggai Sharon, Idit F Schwartz and Gil Chernin
    Citation: BMC Nephrology 2013 14:71
    Content type: Case report Published on:

  24. Hepcidin is a central regulator of iron metabolism. Serum hepcidin levels are increased in patients with renal insufficiency, which may contribute to anemia. Urine hepcidin was found to be increased in some pa...

    Authors: Hilde PE Peters, Coby MM Laarakkers, Peter Pickkers, Rosalinde Masereeuw, Otto C Boerman, Annemarie Eek, Elisabeth AM Cornelissen, Dorine W Swinkels and Jack FM Wetzels
    Citation: BMC Nephrology 2013 14:70
    Content type: Research article Published on:

  25. The epidemic of diabetic nephropathy (DN) has been paralleled by rapid increases in both obesity and diabetes in China. The aim of this study was to investigate the natural history of DN and the association of...

    Authors: Hui-Mei Chen, Wen-Wen Shen, Yong-Chun Ge, Yi-De Zhang, Hong-Lang Xie and Zhi-Hong Liu
    Citation: BMC Nephrology 2013 14:69
    Content type: Research article Published on:

  26. Left ventricular (LV) dyssynchrony is associated with increased risk of all-cause mortality in patients with end-stage renal disease. Our aim was to determine the associations of LV dynamic dyssynchrony with p...

    Authors: Ching-Hui Huang, Chia-Chu Chang, Tzu-Lan Chang and Yu-Jun Chang
    Citation: BMC Nephrology 2013 14:68
    Content type: Research article Published on:

  27. Resistance to ESAs (erythropoietin stimulating agents) is highly prevalent in hemodialysis patients with diabetes and associated with an increased mortality. The aim of this study was to identify predictors fo...

    Authors: Andreas Schneider, Markus P Schneider, Hubert Scharnagl, Alan G Jardine, Christoph Wanner and Christiane Drechsler
    Citation: BMC Nephrology 2013 14:67
    Content type: Research article Published on:

  28. Pulmonary renal syndrome (PRS), denoting the presence of diffuse alveolar hemorrhage and glomerulonephritis as manifestations of systemic autoimmune disease, is very rare in childhood. The coexistence of circu...

    Authors: Radovan Bogdanović, Predrag Minić, Jasmina Marković-Lipkovski, Nataša Stajić, Nataša Savić and Milan Rodić
    Citation: BMC Nephrology 2013 14:66
    Content type: Case report Published on:

  29. Steroid-sensitive idiopathic nephrotic syndrome (SSINS) is most often encountered in sporadic cases of minimal change disease (MCD). Only rare cases of familial forms of MCD have been reported and most of them...

    Authors: Hassib Chehade, Francois Cachat, Eric Girardin, Samuel Rotman, Antonio Jorge Correia, Florence Fellmann and Olivier Bonny
    Citation: BMC Nephrology 2013 14:65
    Content type: Case report Published on:

  30. Anemia secondary to iron deficiency is common in patients with non-dialysis dependent chronic kidney disease (ND-CKD) but it is unclear if oral supplementation is as effective as intravenous (IV) supplementati...

    Authors: Shankar P Nagaraju, Adam Cohn, Ayub Akbari, Janet L Davis and Deborah L Zimmerman
    Citation: BMC Nephrology 2013 14:64
    Content type: Research article Published on:

  31. Lupus nephritis is considered to be a principal cause of morbidity and mortality in SLE. Few studies focus on the association between anti-C1q antibodies in circulation and renal C1q deposition in human lupus ...

    Authors: Ying Tan, Di Song, Li-hua Wu, Feng Yu and Ming-hui Zhao
    Citation: BMC Nephrology 2013 14:63
    Content type: Research article Published on:

  32. Mortality in female patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary angioplasty (pPCI) is higher than in men. We examined gender differences in the prevalence and prognostic...

    Authors: Sofie A Gevaert, Dirk De Bacquer, Patrick Evrard, Marc Renard, Christophe Beauloye, Patrick Coussement, Herbert De Raedt, Peter R Sinnaeve and Marc J Claeys
    Citation: BMC Nephrology 2013 14:62
    Content type: Research article Published on:

  33. Branchio-oto-renal (BOR) syndrome is an autosomal dominant disorder characterized by branchial, ear, and renal anomalies. The most common gene mutated in BOR patients is EYA1, the human homolog of the Drosophila ...

    Authors: Maddalena Gigante, Marilena d’Altilia, Eustacchio Montemurno, Sterpeta Diella, Francesca Bruno, Giuseppe S Netti, Elena Ranieri, Giovanni Stallone, Barbara Infante, Giuseppe Grandaliano and Loreto Gesualdo
    Citation: BMC Nephrology 2013 14:60
    Content type: Case report Published on:

  34. Autosomal dominant polycystic kidney disease (ADPKD) is the most common form of inherited kidney disease that results in renal failure. ADPKD is a systemic disorder with cysts and connective tissue abnormaliti...

    Authors: Jana Reiterová, Jitka Štekrová, Miroslav Merta, Jaroslav Kotlas, Veronika Elišáková, Petr Lněnička, Marie Korabečná, Milada Kohoutová and Vladimír Tesař
    Citation: BMC Nephrology 2013 14:59
    Content type: Case report Published on:

  35. Acute kidney injury (AKI) is an independent risk factor for mortality and is responsible for a significant burden of healthcare expenditure, so accurate measurement of its incidence is important. Administrativ...

    Authors: Laurie A Tomlinson, Alex M Riding, Rupert A Payne, Gary A Abel, Charles R Tomson, Ian B Wilkinson, Martin O Roland and Afzal N Chaudhry
    Citation: BMC Nephrology 2013 14:58
    Content type: Research article Published on:

  36. Chronic kidney disease (CKD) is a major issue in public health. Its prevalence has been calculated using estimation of glomerular filtration rate (GFR) by the creatinine-based equations developed in the Modifi...

    Authors: Pierre Delanaye, Etienne Cavalier, Olivier Moranne, Laurence Lutteri, Jean-Marie Krzesinski and Olivier Bruyère
    Citation: BMC Nephrology 2013 14:57
    Content type: Research article Published on:

  37. Indoxyl sulfate, a uremic toxin, is accumulated in the serum of chronic kidney disease (CKD) patients, accelerating the progression of CKD. In CKD rat kidney, the expressions of nuclear factor (erythroid-deriv...

    Authors: Dilinaer Bolati, Hidehisa Shimizu, Maimaiti Yisireyili, Fuyuhiko Nishijima and Toshimitsu Niwa
    Citation: BMC Nephrology 2013 14:56
    Content type: Research article Published on:

  38. Acute kidney injury (AKI) is a common complication after liver transplantation (LT) and associated with a high mortality. The renal resistive index (RI) is used to assess early renal function impairment in cri...

    Authors: Hai-Ying Kong, Fen Chen, Yong He, Lin-Jiao Wu, Li-Qing Wang, Sheng-Mei Zhu and Shu-Sen Zheng
    Citation: BMC Nephrology 2013 14:55
    Content type: Research article Published on:

  39. Glomerular filtration rate (GFR) is the best index of renal function, but age, gender and ethnicity can putatively affect its values. The aim of this study was to establish reference values for GFR in healthy ...

    Authors: Ariana Aguiar Soares, Aline Bodanese Prates, Letícia Schwerz Weinert, Francisco Veríssimo Veronese, Mirela Jobim de Azevedo and Sandra Pinho Silveiro
    Citation: BMC Nephrology 2013 14:54
    Content type: Research article Published on:

  40. Lipoprotein glomerulopathy (LPG) is a rare inherited renal disease characterized by intraglomerular lipoprotein within the lumina of severely dilated glomerular capillaries. The common clinical presentation of...

    Authors: Yu Wu, Xiaohan Chen, Yuan Yang, Baohe Wang, Xiaoxia Liu, Ye Tao, Ping Fu and Zhangxue Hu
    Citation: BMC Nephrology 2013 14:53
    Content type: Case report Published on:

  41. Proteinuria and dilatation of the urinary tract are both relatively common in pregnancy, the latter with a spectrum of symptoms, from none to severe pain and infection. Proteinuria is a rare occurrence in acut...

    Authors: Giorgina B Piccoli, Rossella Attini, Silvia Parisi, Federica N Vigotti, Germana Daidola, Maria Chiara Deagostini, Martina Ferraresi, Agostino De Pascale, Francesco Porpiglia, Andrea Veltri and Tullia Todros
    Citation: BMC Nephrology 2013 14:52
    Content type: Research article Published on:

  42. The Liu Comorbidity Index uses the United States Renal Data System (USRDS) to quantify comorbidity in chronic dialysis patients, capturing baseline comorbidities from days 91 through 270 after dialysis initiat...

    Authors: Sally K Rigler, James B Wetmore, Jonathan D Mahnken, Lei Dong, Edward F Ellerbeck and Theresa I Shireman
    Citation: BMC Nephrology 2013 14:51
    Content type: Research article Published on:

  43. Patients on maintenance hemodialysis (HD) have much higher levels of adiponectin (Total-APN). Adiponectin and C1q form a protein complex in human blood, and serum C1q-binding adiponectin (C1q-APN) can be measu...

    Authors: Ken Kishida, Naohiro Kishida, Masaaki Arima, Hideaki Nakatsuji, Hironori Kobayashi, Tohru Funahashi and Iichiro Shimomura
    Citation: BMC Nephrology 2013 14:50
    Content type: Research article Published on:

  44. There is concern that not all cases of chronic kidney disease (CKD) are known to general practitioners, leading to an underestimate of its true prevalence. We carried out this study to develop a model to predi...

    Authors: Benjamin Kearns, Hugh Gallagher and Simon de Lusignan
    Citation: BMC Nephrology 2013 14:49
    Content type: Research article Published on:

  45. Aim of this study was to evaluate whether the A736V TMPRSS6 polymorphism, a major genetic determinant of iron metabolism in healthy subjects, influences serum levels of hepcidin, the hormone regulating iron me...

    Authors: Serena Pelusi, Domenico Girelli, Raffaela Rametta, Natascia Campostrini, Carlo Alfieri, Michela Traglia, Paola Dongiovanni, Giovanna Como, Daniela Toniolo, Clara Camaschella, Piergiorgio Messa, Silvia Fargion and Luca Valenti
    Citation: BMC Nephrology 2013 14:48
    Content type: Research article Published on:

  46. Focal segmental glomerulosclerosis (FSGS) is a frequent cause of end-stage renal disease. Renal transplantation in patients with FSGS is often complicated by disease recurrence, which is associated with poor o...

    Authors: Rutger JH Maas, Jeroen KJ Deegens, Jan AJG van den Brand, Elisabeth AM Cornelissen and Jack FM Wetzels
    Citation: BMC Nephrology 2013 14:47
    Content type: Research article Published on:

  47. The objective of this study was to determinate the prevalence of chronic kidney disease (CKD) and the different stages of CKD in patients with type 2 diabetes mellitus (DM2) treated in primary care consults in...

    Authors: Antonio Rodriguez-Poncelas, Josep Garre-Olmo, Josep Franch-Nadal, Javier Diez-Espino, Xavier Mundet-Tuduri, Joan Barrot-De la Puente and Gabriel Coll-de Tuero
    Citation: BMC Nephrology 2013 14:46
    Content type: Research article Published on:

  48. Obesity and metabolic syndrome play causative roles in the increasing prevalence of proteinuria in the general population. However, in young adult women the clinical significance of incidentally discovered pro...

    Authors: Jwa-Kyung Kim, Young-Su Ju, Sung Jin Moon, Young Rim Song, Hyung Jik Kim and Sung Gyun Kim
    Citation: BMC Nephrology 2013 14:45
    Content type: Research article Published on:

  49. Chronic cyclosporine-(CsA)-mediated loss of kidney function is a major clinical problem in organ transplantation. We hypothesized that the mineralocorticoid receptor antagonist eplerenone (EPL) prevents chroni...

    Authors: Finn Thomsen Nielsen, Boye L Jensen, Pernille BL Hansen, Niels Marcussen and Peter Bie
    Citation: BMC Nephrology 2013 14:42
    Content type: Research article Published on:

  50. Effective therapeutic strategies are available to prevent adverse outcomes in patients with chronic kidney disease (CKD) but their clinical results are hindered by unplanned implementation. Coordination of car...

    Authors: Nicolas Rognant, Eric Alamartine, Jean Claude Aldigier, Christian Combe, Benoit Vendrely, Patrice Deteix, Pascal Cluzel, Laurent Juillard, François Vrtovsnik, Christelle Maurice, Sophie Fave and Maurice Laville
    Citation: BMC Nephrology 2013 14:41
    Content type: Research article Published on:
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BMC Nephrology

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