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  1. There are few studies assessing the quality of life of patients with chronic and end stage kidney disease in sub-Saharan Africa. We aimed to describe the health-related quality of life (HRQOL) of patients unde...

    Authors: Gloria Shumbusho, Celestin Hategeka, Marianne Vidler, Jules Kabahizi and Marla McKnight
    Citation: BMC Nephrology 2022 23:345
    Content type: Research Published on:

  2. Hemodialysis patients are followed by routine laboratory testing. There is uncertainty whether these tests always lead to a change in decision-making. This study aims to discover the number of yearly intervent...

    Authors: Claudia Chidiac, Dania Chelala, Dany Nassar, Chadia Beaini, Hiba Azar, Serge Finianos, Celine Boueri, Jenny Hawi, Ibrahim Abdo and Mabel Aoun
    Citation: BMC Nephrology 2022 23:344
    Content type: Research Published on:

  3. The incidence of end stage kidney disease (ESKD) is increasing in Ghana as with the rest of the world. This study compared the sociodemographic, diagnostic characteristics (clinical, biochemical and imaging) a...

    Authors: Perditer Okyere, Isaac Okyere, Grace Essuman, Joseph Attakora, Dorcas Serwaa, Irene Esi Donkoh and Richard K.D. Ephraim
    Citation: BMC Nephrology 2022 23:343
    Content type: Research Published on:

  4. New lipid-lowering therapy at the start of dialysis and measurement of lipid parameters over the follow-up period is not recommended in dialysis patients, which seems unappropriated in clinical practice. We ai...

    Authors: Xiaoran Feng, Xiaojiang Zhan, Yueqiang Wen, FenFen Peng, Xiaoyang Wang, Niansong Wang, Xianfeng Wu and Junnan Wu
    Citation: BMC Nephrology 2022 23:342
    Content type: Research Published on:

  5. Data on the functional status (FS) of patients on maintenance haemodialysis (MHD) and their caregiver burden (CGB) in SSA where patients have fewer weekly dialysis sessions and pay out-of-pocket for dialysis-r...

    Authors: Alex Tatang Mambap, Innocent Abong Che, Maimouna Mahamat and Gloria Enow Ashuntantang
    Citation: BMC Nephrology 2022 23:341
    Content type: Research Published on:

  6. We developed machine learning models to understand the predictors of shorter-, intermediate-, and longer-term mortality among hemodialysis (HD) patients affected by COVID-19 in four countries in the Americas.

    Authors: Adrián M. Guinsburg, Yue Jiao, María Inés Díaz Bessone, Caitlin K. Monaghan, Beatriz Magalhães, Michael A. Kraus, Peter Kotanko, Jeffrey L. Hymes, Robert J. Kossmann, Juan Carlos Berbessi, Franklin W. Maddux, Len A. Usvyat and John W. Larkin
    Citation: BMC Nephrology 2022 23:340
    Content type: Research Published on:

  7. Prior studies support a genetic basis for postoperative acute kidney injury (AKI). We conducted a genome-wide association study (GWAS), assessed the clinical utility of a polygenic risk score (PRS), and estima...

    Authors: Daniel B. Larach, Adam Lewis, Lisa Bastarache, Anita Pandit, Jing He, Anik Sinha, Nicholas J. Douville, Michael Heung, Michael R. Mathis, Jonathan D. Mosley, Jonathan P. Wanderer, Sachin Kheterpal, Matthew Zawistowski, Chad M. Brummett, Edward D. Siew, Cassianne Robinson-Cohen…
    Citation: BMC Nephrology 2022 23:339
    Content type: Research Published on:

  8. The Tablo® Hemodialysis System (Tablo) is an all in one, easy-to-learn device featuring integrated water purification, on demand dialysate production and two-way wireless data transmission and is approved for ...

    Authors: Tahir Zaman, Kasadi Moore, Jennifer Jellerson, Yaadveer Chahal, Joshua Schumacher, Cynthia Dalessandri-Silva and Michael Aragon
    Citation: BMC Nephrology 2022 23:338
    Content type: Research Published on:

  11. Malnutrition is common in critically ill patients, but nutrition status in critically ill patients with acute kidney injury (AKI) has been poorly studied. Our study aimed to investigate the relationship betwee...

    Authors: Na Wang, Ping Wang, Wen Li, Li Jiang, Meiping Wang, Bo Zhu and Xiuming Xi
    Citation: BMC Nephrology 2022 23:335
    Content type: Research Published on:

  12. Tolvaptan was approved in the United States in 2018 for patients with autosomal dominant polycystic kidney disease (ADPKD) at risk of rapid progression as assessed in a 3-year phase 3 clinical trial (TEMPO 3:4...

    Authors: Gregory Mader, Deirdre Mladsi, Myrlene Sanon, Molly Purser, Christine L. Barnett, Dorothee Oberdhan, Terry Watnick and Stephen Seliger
    Citation: BMC Nephrology 2022 23:334
    Content type: Research Published on:

  13. Immunoglobulin A dominant postinfectious glomerulonephritis (IgA PIGN) is a unique medical entity that is rare in the paediatric population. It usually presents with severe renal failure, heavy proteinuria, hy...

    Authors: A. Saghar, G. Klaus, B. Trutnau, M. Kömhoff, H. J. Gröne and S. Weber
    Citation: BMC Nephrology 2022 23:333
    Content type: Case report Published on:

  14. Patients who need a live donor kidney transplant (LDKT) must often ask potential donors (PLDs) themselves. This is a difficult task and healthcare could unburden them by making this first contact, ensuring als...

    Authors: Eva Lagging, Kjerstin Larsson, Jonas Wadström, Linda Gyllström Krekula and Annika Tibell
    Citation: BMC Nephrology 2022 23:332
    Content type: Research Published on:

  15. There are major gaps in the implementation of guideline-concordant care for persons with chronic kidney disease (CKD). The CKD Cascade of Care (C3) initiative seeks to improve CKD care by improving detection and ...

    Authors: Julio A. Lamprea-Montealegre, Priya Joshi, Abigail S. Shapiro, Erin Madden, Krista Navarra, O. Alison Potok, L. Parker Gregg, Tanya Podchiyska, Amy Robinson, Mary K. Goldstein, Carmen A. Peralta, Simerjot K. Jassal, Sankar D. Navaneethan, Dena. E. Rifkin, Virginia Wang, Michael G. Shlipak…
    Citation: BMC Nephrology 2022 23:331
    Content type: Study protocol Published on:

  16. The relationship between the coexistence of depression and moderate chronic kidney disease (CKD) and mortality is unclear. We aimed to investigate whether there is a synergistic effect of depression and modera...

    Authors: Fanchao Meng, Yanjie Qi, Xu Chen, Xiuping Yan, Huanhuan Huang and Fan He
    Citation: BMC Nephrology 2022 23:330
    Content type: Research Published on:

  17. Two alleles (G1 and G2) of the apolipoprotein 1 gene (APOL1) predispose people of African descent to developing or accelerating the course of certain types of kidney disease. Population studies to determine the f...

    Authors: Dona Jeanne Alladagbin, Carlos Gustavo Regis da Silva, Luciano Kalabric Silva, Washington LC dos-Santos and Geraldo Gileno de Sá Oliveira
    Citation: BMC Nephrology 2022 23:329
    Content type: Research Published on:

  19. Chronic kidney disease—mineral and bone disorders (CKD-MBD) is characterised by generalised vascular calcification (VC) and impaired bone health. We aimed to investigate the relationship between VC and bone mi...

    Authors: Jana Uhlinova, Anne Kuudeberg, Kaja Metsküla, Margus Lember and Mai Rosenberg
    Citation: BMC Nephrology 2022 23:327
    Content type: Research Published on:

  20. This study aimed to evaluate the etiologies, comorbidities, and outcomes of acute kidney injury (AKI) in Turkey and determine any potential differences among different geographical parts of the country.

    Authors: Meltem Gursu, Itir Yegenaga, Serhan Tuglular, Belda Dursun, Sibel Gokcay Bek, Simge Bardak, Engin Onan, Serap Demir, Ulver Derici, Ayhan Dogukan, Mustafa Sevinc, Ismail Kocyigit, Eda Altun, Ali Burak Haras, Mehmet Riza Altiparmak and Halil Zeki Tonbul
    Citation: BMC Nephrology 2022 23:326
    Content type: Research article Published on:

  21. The Chinese Government initiated the Donation after Citizens' Death policy in 2010. To now, it has been a major source of organs for transplant. Since it is still a young policy, corresponding clinical evidenc...

    Authors: Xiao Fang, Yan Wang, Rong Liu, Changyan Zhu, Chenguang Wu, Fuqiang He, Shunliang Yang and Dong Wang
    Citation: BMC Nephrology 2022 23:325
    Content type: Research Published on:

  22. Chronic kidney disease (CKD) is a common complication after liver transplantation and is traditionally considered to be secondary to calcineurin inhibitors (CNIs). However, several studies have reported that t...

    Authors: Haijiao Jin, Yuehan Wei, Yongbing Qian, Jiang Zhang, Yao Xu, Hang Zhou, Minfang Zhang, Wenyan Zhou, Chaojun Qi, Wei Jin, Shan Mou, Qin Wang and Jianjun Zhang
    Citation: BMC Nephrology 2022 23:324
    Content type: Research Published on:

  23. Kidney stones have become a worldwide public health problem. The purpose of this research is to study the relationship between plasma cadmium level and the prevalence of kidney stones in an adult population.

    Authors: You Li, Kailian He, Liang Cao, Xu Tang, Ruoyu Gou, Tingyu Luo, Song Xiao, Ziqi Chen, Tingjun Li, Jian Qin, Zhiyong Zhang and Jiansheng Cai
    Citation: BMC Nephrology 2022 23:323
    Content type: Research Published on:

  24. Physical and emotional symptoms are prevalent in patients with kidney-dysfunction requiring dialysis (KDRD) and the rigors of thrice-weekly hemodialysis (HD) may contribute to deteriorated health-related quali...

    Authors: Mariana Murea, Benjamin R. Highland, Wesley Yang, Emily Dressler and Gregory B. Russell
    Citation: BMC Nephrology 2022 23:322
    Content type: Research Published on:

  26. Electronic health records can be used for population-wide identification and monitoring of disease. The Territory Kidney Care project developed algorithms to identify individuals with chronic kidney disease (C...

    Authors: Winnie Chen, Asanga Abeyaratne, Gillian Gorham, Pratish George, Vijay Karepalli, Dan Tran, Christopher Brock and Alan Cass
    Citation: BMC Nephrology 2022 23:320
    Content type: Research Published on:

  27. Sarcopenia is associated with various adverse outcomes in hemodialysis patients. However, current tools for assessing and diagnosing sarcopenia have limited applicability. In this study, we aimed to develop a ...

    Authors: Genlian Cai, Jinping Ying, Mengyan Pan, Xiabing lang, Weiping Yu and Qinqin Zhang
    Citation: BMC Nephrology 2022 23:319
    Content type: Research Published on:

  29. In centre haemodialysis (ICHD) patients have been identified as high risk of contracting Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection due to frequent healthcare contact and poor innat...

    Authors: Louise Rachel Moore, Noor Al-Jaddou, Harsha Wodeyar, Asheesh Sharma, Michael Schulz, Anirudh Rao and Kottarathil Abraham
    Citation: BMC Nephrology 2022 23:317
    Content type: Research Published on:

  30. The co-administration of loop diuretics with thiazide diuretics is a therapeutic strategy in patients with hypertension and volume overload. The aim of this study was to assess the efficacy and safety of treat...

    Authors: Fabio Solis-Jimenez, Lucia Monserrat Perez-Navarro, Ricardo Cabrera-Barron, Jesus Antonio Chida-Romero, Geovana Martin-Alemañy, Edgar Dehesa-López, Magdalena Madero and Rafael Valdez-Ortiz
    Citation: BMC Nephrology 2022 23:316
    Content type: Research Published on:

  31. Exercise and some pre-AKI diets have been shown to improve injury, apoptosis, and lipid profile. In this study, the effect of two different diets along with exercise training on acute kidney injury (AKI) was inve...

    Authors: Nazanin Sabet, Zahra Soltani, Mohammad Khaksari, Maryam Iranpour, Reza Malekpour Afshar, Fatemeh Mousavi Mehdiabadi and Alireza Raji-Amirhasani
    Citation: BMC Nephrology 2022 23:315
    Content type: Research Published on:

  32. Cholesterol crystal embolization syndrome (CES) occurs when an atherosclerotic plaque causes small-vessel embolization, resulting in multi-organ damage. Although CES is pathologically characterized by an infil...

    Authors: Tetsu Sakamoto, Takafumi Yamakawa, Keita Hirano, Arisa Kobayashi, Mio Kasai, Kiyoshi Koizumi, Takashi Yokoo, Satoru Komatsumoto, Toshimitsu Murohisa and Taro Shimizu
    Citation: BMC Nephrology 2022 23:314
    Content type: Case report Published on:

  33. The M-type phospholipase A2 receptor (PLA2R)-associated idiopathic membranous nephropathy (IMN) is a common immune-related disease in adults. Vascular endothelial growth factor A (VEGFA) is the key mediator of...

    Authors: Ben Ke, Jinjing Huang, Zhibing Duan, Wen Shen, Yao Wu, Weiping Tu and Xiangdong Fang
    Citation: BMC Nephrology 2022 23:313
    Content type: Research Published on:

  34. Increased total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and decreased high-density lipoprotein cholesterol (HDL-C) concentrations, are established risk factors for ca...

    Authors: Misghina Weldegiorgis and Mark Woodward
    Citation: BMC Nephrology 2022 23:312
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Nephrology 2022 23:318

  35. Mechanisms by which AKI leads to CKD progression remain unclear. Several urine biomarkers have been identified as independent predictors of progressive CKD. It is unknown whether AKI may result in long-term ch...

    Authors: Ian E. McCoy, Jesse Y. Hsu, Joseph V. Bonventre, Chirag R. Parikh, Alan S. Go, Kathleen D. Liu, Ana C. Ricardo, Anand Srivastava, Debbie L. Cohen, Jiang He, Jing Chen, Panduranga S. Rao, Anthony N. Muiru and Chi-yuan Hsu
    Citation: BMC Nephrology 2022 23:311
    Content type: Research Published on:

  36. Performing percutaneous renal biopsy procedures in lupus nephritis (LN) and nephrotic syndrome presents a unique challenge to the nephrologist because of the risk of bleeding from the procedure and the hyperco...

    Authors: Muhammad Imran Kamarudin, Chandran Nadarajan and Mohamed Ashraf Mohamed Daud
    Citation: BMC Nephrology 2022 23:310
    Content type: Case report Published on:

  38. Acute kidney injury (AKI) was common in the first two waves of the SARS-COV-2 pandemic in critically ill patients. A high percentage of these patients required renal replacement therapy and died in the hospital.

    Authors: Urmila Anandh, Amna Noorin, Syed Khurram Shehzad Kazmi, Sooraj Bannur, Syed Shahkar Ahmed Shah, Mehrin Farooq, Gopikrishna Yedlapati, Waseem Amer, Bonthu Prasad and Indranil Dasgupta
    Citation: BMC Nephrology 2022 23:308
    Content type: Research Published on:

  39. Plasma triglyceride (TG) levels are a significant risk factor for cardiovascular disease (CVD). The APOA5 gene is one of the crucial factors in plasma TG metabolism regulation. The rs662799 polymorphism in the AP...

    Authors: Jerry Jacob, Sylwia Boczkowska, Wojciech Zaluska and Monika Buraczynska
    Citation: BMC Nephrology 2022 23:307
    Content type: Research Published on:

  40. Idiopathic membranous nephropathy (iMN) is recognized as an organ-specific autoimmune disease, mainly caused by anti-PLA2R antibody. This study aimed to study between anti-PLA2R antibody level at diagnosis and...

    Authors: Bihua Wang, Zhidan Zhu, Feng Huang, Haowen Huang, Luxia Tu, Ying Wang, Linfeng Zheng, Jing Zhou and Xin Wei
    Citation: BMC Nephrology 2022 23:306
    Content type: Research Published on:

    The Correction to this article has been published in BMC Nephrology 2022 23:321

  41. Nephrotic syndrome (NS) is associated with increased risk of thromboembolic events (TE) adding to the morbidity and mortality. International guidelines recommend prophylactic anticoagulation in patients with N...

    Authors: Sarah Kelddal, Anne-Mette Hvas, Erik Lerkevang Grove and Henrik Birn
    Citation: BMC Nephrology 2022 23:305
    Content type: Research Published on:

  42. There is a growing literature on guidelines regarding Ramadan fasting for chronic kidney disease (CKD) patients. However, most studies only consider the impact of fasting on renal function. This study addition...

    Authors: Latifa Baynouna AlKetbi, Nico Nagelkerke, Amal AlZarouni, Mouza Al Kuwaiti, Mona Al Ghafli, Salama Al Qahtani, Bushra Al Kaabi, Mariam Al Kaabi, Ali Al Ahbabi, Yousif Al Zeyodi, Kholoud Al Ketheri, Khawla Al Nabooda, Khadija Al Tenaji, Ali AlAlawi and Hanan Abdelbaqi
    Citation: BMC Nephrology 2022 23:304
    Content type: Research article Published on:

  43. Increasing evidence suggests that immune cell infiltration contributes to the pathogenesis and progression of diabetic nephropathy (DN). We aim to unveil the immune infiltration pattern in the glomerulus of DN...

    Authors: Wei ZHOU, Yaoyu LIU, Qinghong Hu, Jiuyao ZHOU and Hua LIN
    Citation: BMC Nephrology 2022 23:303
    Content type: Research Published on:

  45. Treatment burden refers to the work involved in managing one’s health and its impact on well-being and has been associated with nonadherence in patients with chronic illnesses. No kidney transplant (KT)-specif...

    Authors: Elizabeth C. Lorenz, Tanya M. Petterson, Isabella Zaniletti, Kandace A. Lackore, Bradley K. Johnson, Martin L. Mai, Sumi S. Nair, Andrew J. Bentall, Kathleen J. Yost and David T. Eton
    Citation: BMC Nephrology 2022 23:301
    Content type: Research Published on:

  46. Hemodialysis tunneled catheters are prone to failure due to infection or thrombosis. Prediction of catheter dysfunction chance and finding the predisposing risk factors might help clinicians to prolong proper ...

    Authors: Arash Mohazzab, Morteza Khavanin Zadeh, Paria Dehesh, Neda Abdolvand, Zhaleh Rahimi and Sahar Rahmani
    Citation: BMC Nephrology 2022 23:300
    Content type: Research Published on:

  47. Chronic kidney disease (CKD) is a recognized risk factor for severe complications in COVID-19. Our objective was to analyze the association between kidney function / T and B lymphocyte modulatory factors and r...

    Authors: Ladan Mansouri, Senka Sendic, Sebastian Havervall, Charlotte Thålin, Stefan H. Jacobson and Joachim Lundahl
    Citation: BMC Nephrology 2022 23:299
    Content type: Research Published on:

  48. Post-dialysis fatigue is a common and distressing complaint in patients on hemodialysis (HD). The dialysis recovery time (DRT) is a recent and reliable method of Post-dialysis fatigue assessment. We aimed to i...

    Authors: Mohamed Mamdouh Elsayed, Montasser Mohamed Zeid, Osama Mohamed Refai Hamza and Noha Mohamed Elkholy
    Citation: BMC Nephrology 2022 23:298
    Content type: Research Published on:

  49. The transport of water and urea through the erythrocyte membrane is facilitated by aquaporins such as aquaglyceroporin (AQP3), and type B urea transporters (UT-B). As they may play an important role in osmotic...

    Authors: Rafał Zwiech, Agnieszka Bruzda-Zwiech, Ewa Balcerczak, Joanna Szczepańska, Adrian Krygier, Beata Małachowska, Dominika Michałek and Dagmara Szmajda-Krygier
    Citation: BMC Nephrology 2022 23:297
    Content type: Research Published on:

  50. Endocapillary hypercellularity (ECHC) is commonly seen in class IV lupus nephritis (LN), the most common and severe LN in children. Factors influencing early complete remission (CR) in pediatric class IV LN ha...

    Authors: Chunzhen Li, Yanan Han, Lili Zhang, Zhiguo Chen, Mei Jin and Suzhen Sun
    Citation: BMC Nephrology 2022 23:296
    Content type: Research Published on:
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