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  1. Weight change post-kidney transplantation and its associations in Aboriginal and Torres Strait Islander Australians, a group known to have poor patient and graft outcomes, are unknown. Weight change based on b...

    Authors: Sandawana William Majoni, Shahid Ullah, James Collett, Jaquelyne T. Hughes and Stephen McDonald
    Citation: BMC Nephrology 2019 20:232
    Content type: Research article Published on:

  2. Maintenance dialysis is a costly and resource intense activity. In Australia, inadequate health infrastructure and poor access to technically skilled staff can limit service provision in remote areas where man...

    Authors: G. Gorham, K. Howard, Y. Zhao, A. M. S. Ahmed, P. D. Lawton, C. Sajiv, S. W. Majoni, P. Wood, T. Conlon, S. Signal, S. L. Robinson, S. Brown and A. Cass
    Citation: BMC Nephrology 2019 20:231
    Content type: Research article Published on:

  3. Maternal kidney disease (acute kidney injury (AKI), advanced chronic kidney disease (CKD), dependence on dialysis or a kidney transplant) has a substantial impact on pregnancy, with risks of significant perina...

    Authors: Nadom Safi, Elizabeth Sullivan, Zhuoyang Li, Mark Brown, William Hague, Stephen McDonald, Michael J. Peek, Angela Makris, Angela M. O’Brien and Shilpanjali Jesudason
    Citation: BMC Nephrology 2019 20:230
    Content type: Study protocol Published on:

  4. Acute renal failure is a rare occurrence in a patient with an unremarkable past medical history and should always lead to an in depth clinical study. The occurrence in the same healthy young subject, of consec...

    Authors: V. Esposito, D. Catucci, M. Colucci, M. Torreggiani, F. Grosjean and C. Esposito
    Citation: BMC Nephrology 2019 20:229
    Content type: Case report Published on:

  5. Long-term exposure of mercury may induce glomerulonephritis. Clinical and pathological features of mercury-associated glomerulonephritis are not fully clear. This study retrospectively analyzed 35 cases of mer...

    Authors: Ai-bo Qin, Tao Su, Su-xia Wang, Fan Zhang, Fu-de Zhou and Ming-hui Zhao
    Citation: BMC Nephrology 2019 20:228
    Content type: Research article Published on:

  6. Cystinuria is an inherited disorder of renal amino acid transport that causes recurrent nephrolithiasis and significant morbidity in humans. It has an incidence of 1 in 7000 worldwide making it one of the most...

    Authors: Lauren E. Woodard, Richard C. Welch, Ruth Ann Veach, Thomas M. Beckermann, Feng Sha, Edward J. Weinman, Talat Alp Ikizler, Jay A. Tischfield, Amrik Sahota and Matthew H. Wilson
    Citation: BMC Nephrology 2019 20:227
    Content type: Research article Published on:

  8. Hyperkalaemia occurs frequently in many maintenance haemodialysis (MHD) patients after parathyroidectomy (PTX) with secondary hyperparathyroidism (SHPT). However, the clinical risk factors that predict postope...

    Authors: Yu-Huan Song, Guang-Yan Cai, Yue-Fei Xiao, Yi-Ping Wang, Song-Tao Yang and Xiang-Mei Chen
    Citation: BMC Nephrology 2019 20:225
    Content type: Research article Published on:

  9. Primary hyperoxaluria (PH) is a rare inborn disorder of the metabolism of glyoxylate, which causes the hallmark production oxalate and forms insoluble calcium oxalate crystals that accumulate in the kidney and...

    Authors: Ruiming Cai, Minzhuang Lin, Zhiyong Chen, Yongtong Lai, Xianen Huang, Guozhi Zhao, Xuekun Guo, Zhongtang Xiong, Juan Chen, Hui Chen, Qingping Jiang, Shaoyan Liu, Yuexin Yang, Weixiang Liang, Minhui Zou, Tao Liu…
    Citation: BMC Nephrology 2019 20:224
    Content type: Case report Published on:

  10. Anisodamine is used for the treatment of reperfusion injury in various organs. In this study, we investigated the effectiveness and mechanisms of action of anisodamine in promoting recovery from glycerol-induc...

    Authors: Yun-feng Li, Bing-yuan Xu, Ran An, Xin-fang Du, Kun Yu, Jia-hua Sun, Guo-hong Zhang, Wei Wang, Li-ping An and Guang-li Wu
    Citation: BMC Nephrology 2019 20:223
    Content type: Research article Published on:

  11. Carbon dioxide (CO2) accumulation is a challenging issue in critically ill patients. CO2 can be eliminated by renal replacement therapy but studies are scarce and clinical relevance is unknown. We prospectively s...

    Authors: Joop Jonckheer, Herbert Spapen, Aziz Debain, Joy Demol, Marc Diltoer, Olivier Costa, Katrien Lanckmans, Taku Oshima, Patrick M. Honoré, Manu Malbrain and Elisabeth De Waele
    Citation: BMC Nephrology 2019 20:222
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Nephrology 2019 20:312

  12. Cilastatin (CL) is an inhibitor of dehydropeptidase-I, which is safely used in clinical practice to prevent nephrotoxicity of antibiotics. Tacrolimus (TAC) is the most important immunosuppressant in renal tran...

    Authors: Kang Luo, Sun Woo Lim, Jian Jin, Long Jin, Hyo Wook Gil, Dai Sig Im, Hyeon Seok Hwang and Chul Woo Yang
    Citation: BMC Nephrology 2019 20:221
    Content type: Research article Published on:

  13. The ASTRAL trial showed no difference in clinical outcomes between medical therapy and revascularization for atherosclerotic renal vascular disease (ARVD). Here we report a sub-study using echocardiography to ...

    Authors: Darren Green, Diana Vassallo, Kelly Handley, Natalie Ives, Keith Wheatley, Constantina Chrysochou, Janet Hegarty, Julian Wright, Jon Moss, Rajan K. Patel, Chris Deighan, John Webster, Peter Rowe, Sue Carr, Jenny Cross, Jamie O’Driscoll…
    Citation: BMC Nephrology 2019 20:220
    Content type: Research article Published on:

  14. Bacterial peritonitis is a serious complication of patients undergoing peritoneal dialysis (PD). Although the identification of causative organisms and use of appropriate antibiotics are essential for treatmen...

    Authors: Katsuyuki Tanabe, Shugo Okamoto, Sumie Hiramatsu Asano and Jun Wada
    Citation: BMC Nephrology 2019 20:219
    Content type: Case report Published on:

  15. Chronic-active antibody mediated rejection (c-aABMR) is a major contributor to long-term kidney allograft loss. We conducted a retrospective analysis to establish the efficacy of treatment with intravenous imm...

    Authors: Kasia A. Sablik, Marian C. Clahsen-van Groningen, Caspar W. N. Looman, Jeffrey Damman, Madelon van Agteren and Michiel G. H. Betjes
    Citation: BMC Nephrology 2019 20:218
    Content type: Research article Published on:

  16. Klotho is a transmembrane protein acting as a co-receptor for FGF-23 and thus exerts clinical actions on mineral metabolism. The association of secreted Klotho with outcomes in CKD patients is unclear. This st...

    Authors: Evangelos Memmos, Pantelis Sarafidis, Panagiotis Pateinakis, Apostolos Tsiantoulas, Danai Faitatzidou, Panagiotis Giamalis, Vassileios Vasilikos and Aikaterini Papagianni
    Citation: BMC Nephrology 2019 20:217
    Content type: Research article Published on:

  17. Diuresis has been observed within a week following renal transplantation, suggesting that the procedure causes acute disturbance of renal water homeostasis. Aquaporin (AQP) 1 and AQP2, important proteins for r...

    Authors: Sayaka Oshikawa-Hori, Naoko Yokota-Ikeda, Hiroko Sonoda and Masahiro Ikeda
    Citation: BMC Nephrology 2019 20:216
    Content type: Research article Published on:

  18. Survival analysis of patients on maintenance hemodialysis (HD) has been the subject of many studies. No study has evaluated the effect of different factors on the survival time of these patients. In this study...

    Authors: Vahid Ebrahimi, Mohammad Hossein Khademian, Seyed Jalil Masoumi, Mohammad Reza Morvaridi and Shahrokh Ezzatzadegan Jahromi
    Citation: BMC Nephrology 2019 20:215
    Content type: Research article Published on:

  19. Many studies have evaluated the usefulness of creatinine- (eGFRcr) and cystatin C-based estimated glomerular filtration rate (eGFRcys) at specific time points in predicting renal outcome. This study compared t...

    Authors: Suhyun Kim, Subin Hwang, Hye Ryoun Jang, Insuk Sohn, Hyeon Seon Ahn, Hyung-Doo Park, Wooseong Huh, Dong-Chan Jin, Yoon-Goo Kim, Dae Joong Kim, Ha Young Oh and Jung Eun Lee
    Citation: BMC Nephrology 2019 20:214
    Content type: Research article Published on:

  21. Pneumocystis jirovecii pneumonia (PCP) remains an important cause of morbidity and mortality in kidney transplant recipients. While the acute phase toxicity in patients with PCP is well-characterized, there is a ...

    Authors: Ji Eun Kim, Ahram Han, Hajeong Lee, Jongwon Ha, Yon Su Kim and Seung Seok Han
    Citation: BMC Nephrology 2019 20:212
    Content type: Research article Published on:

  22. High serum calcium levels should be avoided in patients on hemodialysis (HD) because they can induce cardiovascular diseases and worsen the patient’s prognosis. In contrast, low serum calcium levels worsen the...

    Authors: Mineaki Kitamura, Yohei Tateishi, Shuntaro Sato, Satoko Kitamura, Yuki Ota, Kumiko Muta, Hiroshi Yamashita, Tadashi Uramatsu, Yoko Obata, Yasushi Mochizuki, Masaharu Nishikido, Tsuyoshi Izumo, Takashi Harada, Satoshi Funakoshi, Takayuki Matsuo, Akira Tsujino…
    Citation: BMC Nephrology 2019 20:210
    Content type: Research article Published on:

  24. Evidence of chronic low levels of exposure to heavy metals in Sri Lanka has emerged in a number of studies carried out in the recent past. The source and magnitude of such exposures have to be understood in or...

    Authors: T. B. Ananda Jayalal, T. W. M. A. Jayaruwan Bandara, Sanath T. C. Mahawithanage, M. A. Jagath Wansapala and Sapthala P. L. Galappaththi
    Citation: BMC Nephrology 2019 20:208
    Content type: Research article Published on:

  26. Successful pregnancy outcomes after in vitro fertilization in kidney transplant recipients have been reported, but few cases of successful pregnancy after ABO-incompatible kidney transplantation have been desc...

    Authors: Akihiro Kosoku, Junji Uchida, Keiko Maeda, Yuki Yoshikawa, Akihiro Hamuro, Hisao Shimada, Kazuya Kabei, Shunji Nishide, Tomoaki Iwai, Nobuyuki Kuwabara, Toshihide Naganuma, Norihiko Kumada, Yoshiaki Takemoto and Tatsuya Nakatani
    Citation: BMC Nephrology 2019 20:206
    Content type: Case report Published on:

  27. Methanol poisoning is a serious public health issue in developing countries, but few data are available in the literature on acute kidney injury (AKI) after methanol intoxication.

    Authors: Shu-Ting Chang, Yu-Ting Wang, Yi-Chou Hou, I-Kuan Wang, Hsiang-Hsi Hong, Cheng-Hao Weng, Wen-Hung Huang, Ching-Wei Hsu and Tzung-Hai Yen
    Citation: BMC Nephrology 2019 20:205
    Content type: Research article Published on:

  28. Despite the interrelationships between obesity, eGFR and albuminuria, few large studies examine how obesity modifies the association between these markers of kidney function and adverse clinical outcomes.

    Authors: Marcello Tonelli, Natasha Wiebe, Csaba P. Kovesdy, Matthew T. James, Scott W. Klarenbach, Braden J. Manns and Brenda R. Hemmelgarn
    Citation: BMC Nephrology 2019 20:204
    Content type: Research article Published on:

  29. Infection is the second most common cause of mortality for patients with end-stage renal disease (ESRD), accompanying with immune dysfunction. Endothelin (EDN) is known to be related to inflammation; however, it ...

    Authors: Chih-Chin Kao, Shih-Ying Cheng, Yu-Jia Wang, Shu-Chen Chien, Yu-Wen Hsu, Mei-Yi Wu, Hsing-Fang Lu, Sean Nam, Tao Sun, Mai-Szu Wu and Wei-Chiao Chang
    Citation: BMC Nephrology 2019 20:203
    Content type: Research article Published on:

  30. Persistent left superior vena cava (PLSVC) is a common vena cava malformation, and drains blood into the right atrium via the dilated coronary sinus in most cases. It is usually asymptomatic and detected incid...

    Authors: Huisi He, Bingyang Li, Yiyi Ma, Yuqiang Zhang, Chaoyang Ye, Changlin Mei, Shengqiang Yu, Bing Dai and Yawei Liu
    Citation: BMC Nephrology 2019 20:202
    Content type: Case report Published on:

  31. A low FT3 level is significantly associated with a variety of kidney disease and acute myocardial infarction (AMI). However, it remains unclear whether low FT3 is associated with CI-AKI in patients who underwe...

    Authors: Kai-Yang Lin, Sun-Ying Wang, Hui Jiang, Han-Chuan Chen, Zhi-Yong Wu, Yan-Song Guo and Peng-Li Zhu
    Citation: BMC Nephrology 2019 20:201
    Content type: Research article Published on:

  32. Chloride is speculated to have nephrotoxic properties. In healthy subjects we tested the hypothesis that acute chloride loading with 3% saline would induce kidney injury, which could be prevented with the loop...

    Authors: F. H. Mose, A. N. Jörgensen, M. H. Vrist, N. P. Ekelöf, E. B. Pedersen and J. N. Bech
    Citation: BMC Nephrology 2019 20:200
    Content type: Research article Published on:

  33. Due to rising vascular comorbidities of patients undergoing dialysis, the prevalence of permanent hemodialysis catheters as hemodialysis access is increasing. However, infection is a major complication of thes...

    Authors: Fani Delistefani, Manuel Wallbach, Gerhard A. Müller, Michael J. Koziolek and Clemens Grupp
    Citation: BMC Nephrology 2019 20:199
    Content type: Research article Published on:

  34. Anabolic-androgenic steroids and growth hormone are among the most commonly used supplements by sportsmen and sportswomen. The aim of this systematic review is to collect and report available data about renal ...

    Authors: Dorna Davani-Davari, Iman Karimzadeh and Hossein Khalili
    Citation: BMC Nephrology 2019 20:198
    Content type: Research article Published on:

  35. Successful vascular access (VA) cannulation is integral to the delivery of adequate dialysis, highlighting the importance of ensuring the viability of arteriovenous access in hemodialysis (HD) patients. Missed...

    Authors: Linda L. Coventry, Jon M. Hosking, Doris T. Chan, Evelyn Coral, Wai H. Lim, Amanda Towell-Barnard, Diane E. Twigg and Claire M. Rickard
    Citation: BMC Nephrology 2019 20:197
    Content type: Research article Published on:

  36. Gait speed (GS) and handgrip strength (HGS), both factors associated with frailty and sarcopenia, are reportedly associated with CV events in the general population. However, little is known about the impact o...

    Authors: Atsumi Kuki, Kentaro Tanaka, Akifumi Kushiyama, Yoshihide Tanaka, Shuta Motonishi, Yasuji Sugano, Toru Furuya and Takashi Ozawa
    Citation: BMC Nephrology 2019 20:196
    Content type: Research article Published on:

  37. Acute kidney injury (AKI) is a major complication of acute myocardial infarction(AMI), which can significantly increase mortality. This study is to analyze the related risk factors and establish a prediction s...

    Authors: Feng-bo Xu, Hong Cheng, Tong Yue, Nan Ye, He-jia Zhang and Yi-pu Chen
    Citation: BMC Nephrology 2019 20:195
    Content type: Research article Published on:

  38. Acid-base imbalance might promote the progression of chronic kidney disease (CKD), but whether nutrient-derived dietary acid load increases the risk of albuminuria or even high normoalbuminuria is unclear.

    Authors: Keiko Kabasawa, Michihiro Hosojima, Ribeka Takachi, Kazutoshi Nakamura, Yumi Ito, Akihiko Saito, Norie Sawada, Shoichiro Tsugane, Junta Tanaka and Ichiei Narita
    Citation: BMC Nephrology 2019 20:194
    Content type: Research article Published on:

  39. The use of metformin in patients with type 2 diabetes mellitus has been associated with lactic acidosis. However, the information available in patients with moderate-severe chronic kidney disease is scarce.

    Authors: Consuelo Pedrós, Mónica Ávila, Ainhoa Gómez-Lumbreras, Marcela Manríquez and Rosa Morros
    Citation: BMC Nephrology 2019 20:193
    Content type: Study protocol Published on:

  40. Chronic kidney disease (CKD) is a worldwide public health problem. Clinical practice guidelines (CPGs) are being developed and implemented in order to improve clinical practice related to the detection and tre...

    Authors: Jorge Coronado Daza, Robin W. M. Vernooij, Karla Salas, Dimelza Osorio and Gerard Urrútia Cuchí
    Citation: BMC Nephrology 2019 20:192
    Content type: Research article Published on:

  41. Thrombophilia due to protein C (PC) and protein S (PS) deficiencies is highly prevalent among patients with stage 5 chronic kidney disease and is reported to arise due to extracorporeal circulation during hemo...

    Authors: Mayuri Ichinose, Naru Sasagawa, Tetsuo Chiba, Katsuhide Toyama, Yuzo Kayamori and Dongchon Kang
    Citation: BMC Nephrology 2019 20:191
    Content type: Research article Published on:

  42. Kidney transplant (KT) patients presenting with cardiovascular (CVD) events are being managed increasingly in non-transplant facilities. We aimed to identify drivers of mortality and costs, including transplan...

    Authors: Amit K. Mathur, Yu-Hui Chang, D. Eric Steidley, Raymond L. Heilman, Nabil Wasif, David Etzioni, Kunam S. Reddy and Adyr A. Moss
    Citation: BMC Nephrology 2019 20:190
    Content type: Research article Published on:

  43. To evaluate renal expression of C4d, a complement component in the classical/mannose binding lectin (MBL) pathway, in patients with primary Sjögren’s syndrome (pSS)-associated renal impairments.

    Authors: Wenli Xia, Bixia Gao, Lin Duan, Yan Li, Yubing Wen, Limeng Chen, Xuemei Li, Falei Zheng and Mingxi Li
    Citation: BMC Nephrology 2019 20:189
    Content type: Research article Published on:

  44. Patients with advanced chronic kidney disease (CKD) exhibit higher prevalence of coronary artery calcification (CaC) than general population. CaC has been proposed as a risk factor for mortality in end-stage C...

    Authors: Marta Cano-Megías, Pablo Guisado-Vasco, Hanane Bouarich, Gabriel de Arriba-de la Fuente, Patricia de Sequera-Ortiz, Concepción Álvarez-Sanz and Diego Rodríguez-Puyol
    Citation: BMC Nephrology 2019 20:188
    Content type: Research article Published on:

  45. Vitamin D deficiency is an important health concern because it is related to several comorbidities and mortality. However, its relationship with the risk of hematuria remains undetermined in the general popula...

    Authors: Hyunjin Ryu, Hyunjeong Cho, Yun Kyu Oh, Kwon Wook Joo, Yon Su Kim, Curie Ahn and Seung Seok Han
    Citation: BMC Nephrology 2019 20:187
    Content type: Research article Published on:

  46. The performance of urinary N-acetyl-β-D-glucosaminidase (uNAG) for the detection of acute kidney injury (AKI) was controversial. uNAG is positively correlated with blood glucose levels. Hyperglycemia is common...

    Authors: Lin Wang, Yujun Deng, Yiling Zhai, Feng Xu, Jinghua Li, Danqing Zhang, Lu Gao, Yating Hou, Xin OuYang, Linhui Hu, Jie Yuan, Heng Ye, Ruibin Chi and Chunbo Chen
    Citation: BMC Nephrology 2019 20:186
    Content type: Research article Published on:

  47. Angiopoietin-like-3 (Angptl3) knockout is known for its protective effects on podocyte injury and proteinuria in the early stage of adriamycin (ADR) nephropathy. The current study re-evaluated the renoprotecti...

    Authors: Rufeng Dai, Haimei Liu, Xinli Han, Junchao Liu, Yihui Zhai, Jia Rao, Qian Shen and Hong Xu
    Citation: BMC Nephrology 2019 20:185
    Content type: Research article Published on:

  48. Cardiovascular morbidity and mortality are highly prevalent in patients with end-stage renal disease, and osteoprotegerin (OPG) may be an important link between bone loss and vascular calcification. This study...

    Authors: Jia-Sian Hou, Yu-Li Lin, Chih-Hsien Wang, Yu-Hsien Lai, Chiu-Huang Kuo, Yi-Maun Subeq and Bang-Gee Hsu
    Citation: BMC Nephrology 2019 20:184
    Content type: Research article Published on:

  49. Accurate prediction of reference ranges of renal lengths facilitates clinical decision making. Currently a single renal-length-reference chart is used for both kidneys, which is solely based on the age of the ...

    Authors: W. D. Duminda, K. G. Pathirana, M. U. J. Fernando, R. A. N. K. K. Samarasinghe, W. D. H. A. Ananda, K. S. P. Silva, C. K. Dissanayake and P. K. B. Mahesh
    Citation: BMC Nephrology 2019 20:183
    Content type: Research article Published on:

  50. Acute kidney injury (AKI) is common after heart surgery. Neutrophil gelatinase-associated lipocalin (NGAL) is produced in injured kidney. NGAL has been used as an early plasma biomarker for AKI in patients und...

    Authors: Arie Passov, Liisa Petäjä, Marjut Pihlajoki, Ulla-Stina Salminen, Raili Suojaranta, Antti Vento, Sture Andersson, Ville Pettilä, Alexey Schramko and Eero Pesonen
    Citation: BMC Nephrology 2019 20:182
    Content type: Research article Published on:
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