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  1. Physical, cognitive and psychosocial functioning are frequently impaired in dialysis patients and impairment in these domains relates to poor outcome. The aim of this analysis was to compare the prevalence of ...

    Authors: I. N. van Loon, M. L. Bots, F. T. J. Boereboom, M. P. C. Grooteman, P. J. Blankestijn, M. A. van den Dorpel, M. J. Nubé, P. M. Ter Wee, M. C. Verhaar and M. E. Hamaker
    Citation: BMC Nephrology 2017 18:217
  2. Patients starting dialysis often have substantial residual kidney function. Incremental hemodialysis provides a hemodialysis prescription that supplements patients’ residual kidney function while maintaining t...

    Authors: Stephanie M. Toth-Manikowski, Surekha Mullangi, Seungyoung Hwang and Tariq Shafi
    Citation: BMC Nephrology 2017 18:216
  3. Autosomal dominant polycystic kidney disease (PKD) is the most common genetic renal disease and the fourth leading cause of end-stage renal disease in the United States. Although there is no cure for PKD, seve...

    Authors: Wen-Ching Tran, David Huynh, Tea Chan, Catherine A. Chesla and Meyeon Park
    Citation: BMC Nephrology 2017 18:214
  4. Patients treated with dialysis have high rates of brain infarcts, brain atrophy, and white matter disease. There are limited data regarding the presence of more subtle damage to brain white matter.

    Authors: David A. Drew, Bang-Bon Koo, Rafeeque Bhadelia, Daniel E. Weiner, Sarah Duncan, Maria Mendoza-De la Garza, Aditi Gupta, Hocine Tighiouart, Tammy Scott and Mark J. Sarnak
    Citation: BMC Nephrology 2017 18:213
  5. Kidney Diseases contribute a significant proportion to the global burden of non-communicable diseases. Haemodialysis services as the main modality of renal replacement therapy in most resource limited countrie...

    Authors: Alfred J. Meremo, David P. Ngilangwa, Masumbuko Y. Mwashambwa, Matobogolo B. Masalu, Janet Kapinga, Rehema Tagalile and Issa Sabi
    Citation: BMC Nephrology 2017 18:212
  6. The prognostic values of baseline, longitudinal high-sensitivity C-reactive protein (hs-CRP) and its change over time on mortality in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) remain...

    Authors: Wei Li, Liping Xiong, Li Fan, Yating Wang, Xuan Peng, Rong Rong, Yagui Qiu, Jiani Shen, Jianxiong Lin, Xueqing Yu and Haiping Mao
    Citation: BMC Nephrology 2017 18:211
  7. Nephropathic cystinosis is a rare inherited metabolic disorder leading to progressive renal failure and extra-renal comorbidity. The prognosis relies on early adherence to cysteamine treatment and symptomatic ...

    Authors: Aurélia Bertholet-Thomas, Julien Berthiller, Velibor Tasic, Behrouz Kassai, Hasan Otukesh, Marcella Greco, Jochen Ehrich, Rejane de Paula Bernardes, Georges Deschênes, Sally-Ann Hulton, Michel Fischbach, Kenza Soulami, Bassam Saeed, Ehsan Valavi, Carlos Jose Cobenas, Bülent Hacihamdioglu…
    Citation: BMC Nephrology 2017 18:210
  8. Although TGF-ß and the transcription factor Egr-1 play an important role in both kidney fibrosis and in response to acute changes of renal medullary osmolarity, their role under sustained hypo- or hyperosmolar...

    Authors: Miklós M. Mózes, Petra Szoleczky, László Rosivall and Gábor Kökény
    Citation: BMC Nephrology 2017 18:209
  9. Critically ill patients requiring renal replacement therapy (RRT) are at risk of disease-related bleeding. Systemic heparinization should be avoided. AN69ST, a polyethyleneimine-treated polyacrylonitrile (AN69...

    Authors: Tao Su, Qizhuang Jin and Zhongyuan Liu
    Citation: BMC Nephrology 2017 18:208
  10. End-Stage renal disease (ESRD) causes considerable morbidity and mortality, and significantly alters patients’ quality of life. There are very few published data on this problem in the French Overseas territor...

    Authors: Dévi Rita Rochemont, Mohamed Meddeb, Raoul Roura, Cécile Couchoud, Mathieu Nacher and Célia Basurko
    Citation: BMC Nephrology 2017 18:207
  11. The role of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) reducing risk of cardiovascular events (CVEs) and preserving kidney function in patients with chronic kidne...

    Authors: Youxia Liu, Xinxin Ma, Jie Zheng, Junya Jia and Tiekun Yan
    Citation: BMC Nephrology 2017 18:206
  12. Chronic kidney disease (CKD) is a major contributor to mortality in the general population. Understanding the factors that drive this process will help delay progression of CKD. The study aimed to estimate the...

    Authors: Phisitt Vejakama, Atiporn Ingsathit, Mark McEvoy, John Attia and Ammarin Thakkinstian
    Citation: BMC Nephrology 2017 18:205
  13. High levels of fibroblast growth factor-23 (FGF23) are associated with mortality. In chronic kidney disease (CKD), FGF23 levels rise as renal function declines. We analyzed the contribution of laboratory value...

    Authors: Daisy Liu, Ana Catalina Alvarez-Elías, Brooke Wile, Vladimir Belostotsky and Guido Filler
    Citation: BMC Nephrology 2017 18:204
  14. Acute kidney injury (AKI) places a heavy burden on the healthcare system in China and is usually misdiagnosed. However, there are limited studies that have described the epidemiology and diagnosis of AKI in Ch...

    Authors: Xiaoyan Cheng, Buyun Wu, Yun Liu, Huijuan Mao and Changying Xing
    Citation: BMC Nephrology 2017 18:203
  15. Patients with acute myocardial infarction are at high risk for acute kidney injury. Novel biomarkers that can predict acute kidney injury in AMI may allow timely interventions. C-terminal fragment of agrin (CA...

    Authors: Spyridon Arampatzis, Georgios Chalikias, Vasilios Devetzis, Stavros Konstantinides, Uyen Huynh-Do and Dimitrios Tziakas
    Citation: BMC Nephrology 2017 18:202
  16. Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults. MN is a clinically heterogeneous disease and it is difficult to accurately predict outcomes (including end stage renal failure)...

    Authors: Sanjana Gupta, John Connolly, Ruth J Pepper, Stephen B Walsh, Magdi M Yaqoob, Robert Kleta and Neil Ashman
    Citation: BMC Nephrology 2017 18:201
  17. Dialysis initiation rates among older adults, aged 75 years or greater, are increasing at a faster rate than for younger age groups. Older adults with advanced CKD (eGFR < 30 ml/min/1.73 m2) typically lose renal ...

    Authors: Steven J. Rosansky, Jane Schell, Joseph Shega, Jennifer Scherer, Laurie Jacobs, Cecile Couchoud, Deidra Crews and Matthew McNabney
    Citation: BMC Nephrology 2017 18:200
  18. The use of dipstick proteinuria to screen Chronic Kidney Disease of uncertain aetiology (CKDu) in Sri Lanka is a recently debated matter of dispute. The aim of this study was to assess the suitability of bioma...

    Authors: Samantha Ratnayake, Zeid Badurdeen, Nishantha Nanayakkara, Tilak Abeysekara, Neelakanthi Ratnatunga and Ranjith Kumarasiri
    Citation: BMC Nephrology 2017 18:199

    The Erratum to this article has been published in BMC Nephrology 2017 18:236

  19. Only a few research is available on the effects of home-based exercise training on pre-dialysis chronic kidney disease (CKD) patients. Therefore, we aimed to elucidate the effect of home-based exercise therapy...

    Authors: Koji Hiraki, Yugo Shibagaki, Kazuhiro P. Izawa, Chiharu Hotta, Akiko Wakamiya, Tsutomu Sakurada, Takashi Yasuda and Kenjiro Kimura
    Citation: BMC Nephrology 2017 18:198
  20. Poor quality of life (QOL) and a high prevalence of depression have been identified among end-stage renal disease (ESRD) patients undergoing hemodialysis (HD). We aimed to evaluate the associations between rel...

    Authors: Paulo Roberto Santos, José Roberto Frota Gomes Capote Júnior, José Renan Miranda Cavalcante Filho, Ticianne Pinto Ferreira, José Nilson Gadelha dos Santos Filho and Stênio da Silva Oliveira
    Citation: BMC Nephrology 2017 18:197
  21. Although angiotensin-converting enzyme inhibitors (ACEI) and angiotensin-II receptor blockers (ARB) have been shown to preserve residual kidney function in a select group of Asian patients undergoing continuou...

    Authors: Jenny I. Shen, Anjali B. Saxena, Sitaram Vangala, Satvinder K. Dhaliwal and Wolfgang C. Winkelmayer
    Citation: BMC Nephrology 2017 18:196
  22. Primary hyperoxaluria type 1 (PH1), is a rare and heterogeneous disease and one of major causes of renal insufficiency in Tunisia, caused by mutations in the AGXT gene. 33-34InsC mutation, was mainly described in...

    Authors: Ibtihel Benhaj Mbarek, Saoussen Mdimeg, Amira Moussa, Dorsaf Zellama, Hayat Kaarout, Jaouida Abdelmoula, Abdellatif Achour, Saoussen Abroug, Asma Omezzine and Ali Bouslama
    Citation: BMC Nephrology 2017 18:195
  23. Cisplatin (CP) is commonly used in the treatment of different types of cancer but nephrotoxicity has been a major limiting factor. Therefore, the present study aimed to study the possible protective effect of ...

    Authors: Ali R. Alhoshani, Mohamed M. Hafez, Sufia Husain, Abdel Malek Al-sheikh, Moureq R. Alotaibi, Salim S. Al Rejaie, Musaad A. Alshammari, Mashal M. Almutairi and Othman A. Al-Shabanah
    Citation: BMC Nephrology 2017 18:194
  24. Epidermolysis bullosa is a group of diseases caused by mutations in genes for proteins responsible for cells’ anchorage at the dermo-epidermal junction. Their common feature are dysfunctional or even absent co...

    Authors: Michał Małecki, Maciej Domański and Kazimierz Ciechanowski
    Citation: BMC Nephrology 2017 18:193
  25. Association between metabolic syndrome (MS) and mildly reduced estimated glomerular filtration rates (eGFRs) remains unclear. Therefore, we aimed to evaluate the association between MS and a mildly reduced eGF...

    Authors: Wen Hu, Xiao-Juan Wu, Yao-Jun Ni, Hai-Rong Hao, Wei-Nan Yu and Hong-Wen Zhou
    Citation: BMC Nephrology 2017 18:192
  26. Vascular calcifications are highly prevalent in hemodialysis patients. Dephosphorylated-uncarboxylated MGP (dp-ucMGP) was found to increase in vitamin K-deficient patients and may be associated with vascular c...

    Authors: Mabel Aoun, Maha Makki, Hiba Azar, Hiam Matta and Dania Nehme Chelala
    Citation: BMC Nephrology 2017 18:191
  27. Inflammatory processes are very important in the development of kidney disease. Nevertheless, the association between white blood cell (WBC) count and the risk of renal dysfunction has not been well-establishe...

    Authors: Fangfang Fan, Jia Jia, Jianping Li, Yong Huo and Yan Zhang
    Citation: BMC Nephrology 2017 18:190
  28. Chronic kidney disease [CKD] is recognised as a global public health problem. Until recently, the majority of information informing on CKD has been generated from renal registries reporting on patients with en...

    Authors: Sree K. Venuthurupalli, Wendy E. Hoy, Helen G. Healy, Anne Cameron and Robert G. Fassett
    Citation: BMC Nephrology 2017 18:189
  29. Previous studies have indicated that reduced kidney function and albuminuria are associated with increased risk of mortality and adverse cardiovascular outcomes, however, the evidence from the Asian population...

    Authors: Jinwei Wang, Fang Wang, Shiwei Liu, Maigeng Zhou, Luxia Zhang and Minghui Zhao
    Citation: BMC Nephrology 2017 18:188
  30. Low molecular weight heparins (LMWH) have been extensively studied and became the treatment of choice for several indications including pulmonary embolism. While their efficacy in hemodialysis is considered si...

    Authors: Hind Harrak Lazrak, Émilie René, Naoual Elftouh, Martine Leblanc and Jean-Philippe Lafrance
    Citation: BMC Nephrology 2017 18:187
  31. Results concerning the association between peritoneal dialysis-related peritonitis and mortality in peritoneal dialysis patients are inconclusive, with one potential reason being that the time-dependent effect...

    Authors: Hongjian Ye, Qian Zhou, Li Fan, Qunying Guo, Haiping Mao, Fengxian Huang, Xueqing Yu and Xiao Yang
    Citation: BMC Nephrology 2017 18:186
  32. These guidelines cover the care of patients from the period following kidney transplantation until the transplant is no longer working or the patient dies. During the early phase prevention of acute rejection ...

    Authors: Richard J. Baker, Patrick B. Mark, Rajan K. Patel, Kate K. Stevens and Nicholas Palmer
    Citation: BMC Nephrology 2017 18:174
  33. Acute kidney injury (AKI) is a severe complication associated with abdominal aortic aneurysm (AAA) repair. In this study, we evaluated the incidence, risk factors and in-hospital mortality of AKI in patients a...

    Authors: Ying Tang, Junzhe Chen, Kai Huang, Dan Luo, Peifen Liang, Min Feng, Wenxin Chai, Erik Fung, Hui Yao Lan and Anping Xu
    Citation: BMC Nephrology 2017 18:184
  34. Septic acute kidney injury affects 40–50% of all septic patients. Molecular differences between septic patients with and without acute kidney injury (AKI) are only poorly understood. Here, we investigated gene...

    Authors: Martin Matejovic, Lenka Valesova, Jan Benes, Roman Sykora, Roman Hrstka and Jiri Chvojka
    Citation: BMC Nephrology 2017 18:183
  35. Perfusion deficits likely play an important role in the development of renal dysfunction in sepsis. Renal denervation may improve kidney perfusion and metabolism.

    Authors: Emiel Hendrik Post, Fuhong Su, Koji Hosokawa, Fabio Silvio Taccone, Antoine Herpain, Jacques Creteur, Daniel De Backer and Jean-Louis Vincent
    Citation: BMC Nephrology 2017 18:182
  36. Growth impairment remains common in children with chronic kidney disease (CKD). Available literature indicates low level of recombinant human growth hormone (rhGH) utilization in short children with CKD. Despi...

    Authors: Oleh M. Akchurin, Amy J. Kogon, Juhi Kumar, Christine B. Sethna, Hoda T. Hammad, Paul J. Christos, John D. Mahan, Larry A. Greenbaum and Robert Woroniecki
    Citation: BMC Nephrology 2017 18:181
  37. This study aimed to evaluate the prevalence of sedentarism, and to assess physical capacity and nutritional status in a cohort of older patients on peritoneal dialysis (PD), with respect to age-matched non-dialys...

    Authors: Adamasco Cupisti, Claudia D’Alessandro, Viviana Finato, Claudia Del Corso, Battista Catania, Gian Marco Caselli and Maria Francesca Egidi
    Citation: BMC Nephrology 2017 18:180
  38. Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary disorder with unclear disease mechanism. Currently, overt hypertension and increased renal volume are the best predictors of renal fu...

    Authors: Ismail Kocyigit, Serpil Taheri, Elif Funda Sener, Eray Eroglu, Fahir Ozturk, Aydin Unal, Kezban Korkmaz, Gokmen Zararsiz, Murat Hayri Sipahioglu, Yusuf Ozkul, Bulent Tokgoz, Oktay Oymak, Tevfik Ecder and Jonas Axelsson
    Citation: BMC Nephrology 2017 18:179
  39. Adherence to diet recommendations, fluid restriction, prescribed medications, and attendance at hemodialysis (HD) sessions are essential for optimal and effective treatment of patients with end-stage renal dis...

    Authors: Karam Sh. Naalweh, Mohammad A. Barakat, Moutaz W. Sweileh, Samah W. Al-Jabi, Waleed M. Sweileh and Sa’ed H. Zyoud
    Citation: BMC Nephrology 2017 18:178
  40. Acute kidney injury (AKI) following cardiac surgery is common and associated with poor patient outcomes. Early risk assessment for development of AKI remains a challenge. The combination of urinary tissue inhi...

    Authors: Yimei Wang, Zhouping Zou, Jifu Jin, Jie Teng, Jiarui Xu, Bo Shen, Wuhua Jiang, Yamin Zhuang, Lan Liu, Zhe Luo, Chunsheng Wang and Xiaoqiang Ding
    Citation: BMC Nephrology 2017 18:177
  41. The benefit of early dialysis initiation remains controversial with a paucity of data in Asians. Therefore, we undertook this study to investigate the association between timing of initiation of dialysis and m...

    Authors: Liang Feng, Ai Zhen Jin, John Carson Allen, Khuan Yew Chow and Tazeen Hasan Jafar
    Citation: BMC Nephrology 2017 18:176
  42. In this prospective study, we aimed to assess the haemodynamic changes before and after haemodialysis (HD) in cardiac healthy subjects on chronic HD by imaging methods and endocrine markers of fluid balance.

    Authors: Franz Maximilian Rasche, Stephan Stoebe, Thomas Ebert, Silvana Feige, Andreas Hagendorff, Wilma Gertrud Rasche, Filip Barinka, Volker Busch, Ulrich Sack, Jochen G. Schneider and Stephan Schiekofer
    Citation: BMC Nephrology 2017 18:175
  43. The blood urea nitrogen to creatinine ratio (BCR) has been used since the early 1940s to help clinicians differentiate between prerenal acute kidney injury (PR AKI) and intrinsic AKI (I AKI). This ratio is sim...

    Authors: Guillaume Manoeuvrier, Kalyane Bach-Ngohou, Eric Batard, Damien Masson and David Trewick
    Citation: BMC Nephrology 2017 18:173
  44. Critically ill patients in intensive care face hazardous conditions. Among these, acute kidney injury (AKI) is frequently seen as a result of sepsis. Early diagnosis of kidney injury is of the utmost importanc...

    Authors: Sahra Pajenda, Karl Mechtler and Ludwig Wagner
    Citation: BMC Nephrology 2017 18:172
  45. Kidney transplantation is the renal replacement therapy of choice for end stage renal disease. To ensure safety regular audit of the donation process is necessary. The aim of this study was to assess the evalu...

    Authors: A. Muturi, V. Kotecha and S. Kanyi
    Citation: BMC Nephrology 2017 18:171
  46. The diagnosis of myeloma, a plasma dyscrasia, often results from the workup of unexplained renal disease. Persistent renal failure in myeloma is commonly caused by tubular nephropathy due to circulating immuno...

    Authors: Chung-Kuan Wu, An-Hang Yang, Hung-Chih Lai and Bing-Shi Lin
    Citation: BMC Nephrology 2017 18:170
  47. Little is known about determinants of quality of life (QoL) in autosomal dominant polycystic kidney disease (ADPKD). Recent studies suggest that QoL in ADPKD is determined by more factors than mere renal funct...

    Authors: Myrte K. Neijenhuis, Wietske Kievit, Ronald D. Perrone, Jeff A. Sloan, Patricia Erwin, Mohammad Hassan Murad, Tom J. G. Gevers, Marie C. Hogan and Joost P. H. Drenth
    Citation: BMC Nephrology 2017 18:169

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