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  1. Reducing LDL cholesterol (LDL-C) with statin-based therapy reduces the risk of major atherosclerotic events among patients with chronic kidney disease (CKD), with no evidence of an excess risk of cancer or dea...

    Authors: C. Reith, N. Staplin, W. G. Herrington, W. Stevens, J. Emberson, R. Haynes, M. Mafham, J. Armitage, A. Cass, J. C. Craig, L. Jiang, T. Pedersen, C. Baigent and M. J. Landray
    Citation: BMC Nephrology 2017 18:147
  2. Basic and translational research supports beneficial effects of statins on bone metabolism. Clinical studies suggest that statin use may reduce the risk of hip fractures in the general population. Whether stat...

    Authors: Chandan Vangala, Colin R. Lenihan, Maria E. Montez-Rath, Sumi Sukumaran Nair, Sankar D. Navaneethan, Venkat Ramanathan and Wolfgang C. Winkelmayer
    Citation: BMC Nephrology 2017 18:145
  3. Poor physical performance and protein-energy wasting (PEW) are health issues of major concern in haemodialysis patients. The conventional haemodialysis (CHD) regime, three times per week 3–5 h, is subject of d...

    Authors: Manouk Dam, Floor Neelemaat, Trudeke Struijk-Wielinga, Peter J. Weijs and Brigit C. van Jaarsveld
    Citation: BMC Nephrology 2017 18:144
  4. Acute kidney injury (AKI) is being increasingly recognised in ageing populations. There are a paucity of data about AKI risk factors among older individuals with diabetes and infections, who are at particularl...

    Authors: Anu Jain, Helen I. McDonald, Dorothea Nitsch, Laurie Tomlinson and Sara L. Thomas
    Citation: BMC Nephrology 2017 18:142
  5. Missing preadmission serum creatinine (SCr) values are a common obstacle to assess acute kidney injury (AKI) diagnosis and outcomes. The Kidney Disease Improving Global Outcomes (KDIGO) guidelines suggest usin...

    Authors: Amélie Bernier-Jean, William Beaubien-Souligny, Rémi Goupil, François Madore, François Paquette, Stéphan Troyanov and Josée Bouchard
    Citation: BMC Nephrology 2017 18:141
  6. Gitelman syndrome (GS) is a rare autosomal recessively inherited salt-wasting tubulopathy associated with mutations in the SLC12A3 gene, which encodes for NaCl cotransporter (NCC) in the kidney.

    Authors: Chandrika Jayakanthi Subasinghe, Nirmala Dushyanthi Sirisena, Chula Herath, Knut Erik Berge, Trond Paul Leren, Uditha Bulugahapitiya and Vajira Harshadeva Weerabaddana Dissanayake
    Citation: BMC Nephrology 2017 18:140
  7. IgG4-related disease is a recently described pathologic entity. This is the case of a patient with nephrotic syndrome and lymphadenopathy due to IgG4-related disease. Such a kidney involvement is quite peculia...

    Authors: Justine Huart, Stéphanie Grosch, Christophe Bovy, Michel Moutschen and Jean-Marie Krzesinski
    Citation: BMC Nephrology 2017 18:139
  8. Preserved residual kidney function (RKF) and normal fluid status are associated with better patient outcomes in incident haemodialysis patients. The objective of this trial is to determine whether using bioimp...

    Authors: Simon J. Davies, Fergus J. Caskey, David Coyle, Elizabeth Lindley, Jamie Macdonald, Sandip Mitra, Martin Wilkie, Andrew Davenport, Ken Farrington, Indranil Dasgupta, Paula Ormandy, Lazaros Andronis, Ivonne Solis-Trapala and Julius Sim
    Citation: BMC Nephrology 2017 18:138
  9. Calciphylaxis is a serious complication in patients with chronic kidney disease associated mineral and bone disorder. It can occur in conditions with low and high bone turnover. So far, there are no definite d...

    Authors: Margret Patecki, Gabriele Lehmann, Jan Hinrich Bräsen, Jessica Schmitz, Anna Bertram, Lars Daniel Berthold, Hermann Haller and Wilfried Gwinner
    Citation: BMC Nephrology 2017 18:137
  10. Whilst still rare, the incidence of paediatric stone disease is increasing in developed countries and it is important to evaluate the aetiology. We set up a dedicated renal stone service for children combining...

    Authors: Naomi Issler, Stephanie Dufek, Robert Kleta, Detlef Bockenhauer, Naima Smeulders and William van‘t Hoff
    Citation: BMC Nephrology 2017 18:136
  11. Screening for persistent albuminuria among the high-risk population is important for early detection of CKD while studies regarding screening protocol and related cost-effectiveness analysis are limited. This ...

    Authors: Huaiyu Wang, Li Yang, Fang Wang and Luxia Zhang
    Citation: BMC Nephrology 2017 18:135
  12. Patients with an impaired renal function show a high incidence of bone and mineral disturbances. These ‘chronic kidney disease – mineral and bone disorders’ (CKD-MBD) range from high turnover osteoporosis to a...

    Authors: Ruth G. G. Hiller, Margret Patecki, Claudia Neunaber, Janin Reifenrath, Jan T. Kielstein and Heike Kielstein
    Citation: BMC Nephrology 2017 18:134
  13. Simkania negevensis is an obligate intracellular bacterium belonging to the family Simkaniaceae in the Chlamydiales order. It is considered an ubiquitous microorganism and aquatic envi...

    Authors: Andrea Angeletti, Roberta Biondi, Giuseppe Battaglino, Eleonora Cremonini, Giorgia Comai, Irene Capelli, Gabriele Donati, Roberto Cevenini, Manuela Donati and Gaetano La Manna
    Citation: BMC Nephrology 2017 18:133
  14. Whether screening for chronic kidney disease (CKD) can improve the care of persons at high risk for complications remains uncertain. We describe the design and early implementation experience of a pilot, clust...

    Authors: Carmen A. Peralta, Martin Frigaard, Anna D. Rubinsky, Leticia Rolon, Lowell Lo, Santhi Voora, Karen Seal, Delphine Tuot, Shirley Chao, Kimberly Lui, Phillip Chiao, Neil Powe and Michael Shlipak
    Citation: BMC Nephrology 2017 18:132
  15. Patients who start renal replacement therapy (RRT) for End-Stage Kidney Disease (ESKD) without having had timely access to specialist renal services have poor outcomes. At one NHS Trust in England, a community...

    Authors: Hugh Gallagher, Shona Methven, Anna Casula, Nicola Thomas, Charles R. V. Tomson, Fergus J. Caskey, Tracey Rose, Stephen J. Walters, David Kennedy, Anne Dawnay, Martin Cassidy, Richard Fluck, Hugh C. Rayner and Michael Nation
    Citation: BMC Nephrology 2017 18:131
  16. Ischemia and reperfusion (I/R) is one of the major causes of acute kidney injury (AKI). Citrate reduces hypoxia-induced mitochondrial energetic deficits in isolated proximal tubules. Moreover, citrate anticoag...

    Authors: Anja Bienholz, Jonas Reis, Pinar Sanli, Herbert de Groot, Frank Petrat, Hana Guberina, Benjamin Wilde, Oliver Witzke, Fuat H. Saner, Andreas Kribben, Joel M. Weinberg and Thorsten Feldkamp
    Citation: BMC Nephrology 2017 18:130
  17. Coronary artery calcification (CAC) is highly prevalent among dialysis patients and is associated with increased cardiovascular and all cause mortality. Magnesium (Mg) inhibits vascular calcification in animal...

    Authors: Amber O. Molnar, Mohan Biyani, Ian Hammond, John Paul Harmon, Susan Lavoie, Brendan McCormick, Manish M. Sood, Jessica Wagner, Elena Pena and Deborah L. Zimmerman
    Citation: BMC Nephrology 2017 18:129
  18. Dementia is common in end-stage renal disease (ESRD) patients on hemodialysis (HD) and is associated with worse outcomes. This study aimed to investigate the risk of major adverse cardiac and cerebrovascular e...

    Authors: Sung Min Jung, Clara Tammy Kim, Ea Wha Kang, Kyoung Hoon Kim, Shina Lee, Hyung Jung Oh, Seung-Jung Kim, Duk-Hee Kang, Kyu Bok Choi, Dong-Ryeol Ryu and Hyunwook Kim
    Citation: BMC Nephrology 2017 18:128
  19. Proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) is a form of renal involvement by monoclonal IgG deposits that was found in mesangial, subendothelial or subepithelial regions. The distri...

    Authors: Rio Noto, Nozomu Kamiura, Yuichiro Ono, Sumie Tabata, Shigeo Hara, Hideki Yokoi, Akihiro Yoshimoto and Motoko Yanagita
    Citation: BMC Nephrology 2017 18:127
  20. Home telemonitoring has developed considerably over recent years in chronic diseases in order to improve communication between healthcare professionals and patients and to promote early detection of deteriorat...

    Authors: Nathalie Thilly, Jacques Chanliau, Luc Frimat, Christian Combe, Pierre Merville, Philippe Chauveau, Pierre Bataille, Raymond Azar, David Laplaud, Christian Noël and Michèle Kessler
    Citation: BMC Nephrology 2017 18:126
  21. Sleep apnea is common and associated with poor outcome in severe chronic kidney disease, but validated screening tools are not available. Our objectives were to determine the prevalence of sleep apnea in this ...

    Authors: Hsin-Chia Huang, Giles Walters, Girish Talaulikar, Derek Figurski, Annette Carroll, Mark Hurwitz, Krishna Karpe and Richard Singer
    Citation: BMC Nephrology 2017 18:125
  22. Drug induced kidney injury is a frequent adverse event which contributes to morbidity and increased healthcare utilization. Our current knowledge of drug induced kidney disease is limited due to varying defini...

    Authors: Linda Awdishu and Ravindra L. Mehta
    Citation: BMC Nephrology 2017 18:124
  23. Pre-produced bicarbonate concentrates (PPC) are still widely used in developing countries despite its cost and risk but Central Concentrate System (CCS) is lacking in data to support its wider adoption.

    Authors: K. Fauziah, K. W. Go, A. Ghazali, M. Zaki and T. O. Lim
    Citation: BMC Nephrology 2017 18:123
  24. Paraquat ingestion is frequently fatal. While biomarkers of kidney damage increase during paraquat-induced acute kidney injury (AKI), significant concurrent proteinuria may alter diagnostic thresholds for diag...

    Authors: Fahim Mohamed, Nicholas A. Buckley, John W. Pickering, Klintean Wunnapuk, Sandamali Dissanayake, Umesh Chathuranga, Indika Gawarammana, Shaluka Jayamanne and Zoltan H. Endre
    Citation: BMC Nephrology 2017 18:122
  25. Accidental intake of mushrooms of the Cortinarius species (deadly webcap) may cause irreversible renal damage and the need for dialysis or transplantation. The species is found in forests of Northern Europe, Scan...

    Authors: Heidi Hedman, Johan Holmdahl, Johan Mölne, Kerstin Ebefors, Börje Haraldsson and Jenny Nyström
    Citation: BMC Nephrology 2017 18:121
  26. There is still an ongoing discussion on the prognostic value of cystatin C in assessment of kidney function. Accordingly, the present study aimed to conduct a meta-analysis to provide evidence for the prognost...

    Authors: Babak Nakhjavan-Shahraki, Mahmoud Yousefifard, Neamatollah Ataei, Masoud Baikpour, Fatemeh Ataei, Behnaz Bazargani, Arash Abbasi, Parisa Ghelichkhani, Faezeh Javidilarijani and Mostafa Hosseini
    Citation: BMC Nephrology 2017 18:120
  27. The highly burdensome effects of kidney failure and its management impose many life-altering changes on patients. Better understanding of successful coping strategies will inform patients and help health care ...

    Authors: Lalita Subramanian, Martha Quinn, Junhui Zhao, Laurie Lachance, Jarcy Zee and Francesca Tentori
    Citation: BMC Nephrology 2017 18:119
  28. Iron deficiency anemia (IDA) is a common manifestation of chronic kidney disease (CKD), affecting most patients on hemodialysis and imposing a substantial clinical burden. Treatment with iron supplementation i...

    Authors: Iain C. Macdougall, Naomi V. Dahl, Kristine Bernard, Zhu Li, Alka Batycky and William E. Strauss
    Citation: BMC Nephrology 2017 18:117

    The Correction to this article has been published in BMC Nephrology 2018 19:97

  29. Chronic kidney disease (CKD) is a major cause of morbidity and mortality in Sub-Saharan Africa (SSA). The majority of studies on CKD in SSA have been conducted among HIV-infected populations and mainly from la...

    Authors: Robert Kalyesubula, Joaniter I. Nankabirwa, Isaac Ssinabulya, Trishul Siddharthan, James Kayima, Jane Nakibuuka, Robert A. Salata, Charles Mondo, Moses R. Kamya and Donald Hricik
    Citation: BMC Nephrology 2017 18:116
  30. Hypertension and chronic kidney disease (CKD) are common conditions and both are major risk factors for cardiovascular events. The objectives were 1) to study the prevalence of CKD in hypertensive patients and...

    Authors: Rungroj Krittayaphong, Ram Rangsin, Bandit Thinkhamrop, Cameron Hurst, Suthee Rattanamongkolgul, Nintita Sripaiboonkij and Wipaporn Wangworatrakul
    Citation: BMC Nephrology 2017 18:115
  31. Recent studies highlight a negative association between total bilirubin concentrations and albuminuria in patients with type 2 diabetes mellitus. Our study evaluated the relationship between bilirubin concentr...

    Authors: Xu Li, Lei Zhang, Haibing Chen, Kaifeng Guo, Haoyong Yu, Jian Zhou, Ming Li, Qing Li, Lianxi Li, Jun Yin, Fang Liu, Yuqian Bao, Junfeng Han and Weiping Jia
    Citation: BMC Nephrology 2017 18:114
  32. Increased plasma Urotensin II (UII) levels have been found in adults with renal diseases. Studies in children are scarce. The objective of the study is to estimate plasma UII levels in subjects with chronic ki...

    Authors: Anastasia Garoufi, Styliani Drapanioti, Antonios Marmarinos, Varvara Askiti, Andromachi J. Mitsioni, Maria Mila, Georgia Grigoriadou, Dimitrios Georgakopoulos, Constantinos J. Stefanidis and Dimitrios Gourgiotis
    Citation: BMC Nephrology 2017 18:113
  33. Additional urinary biomarkers for diabetic nephropathy (DN) are needed, providing early and reliable diagnosis and new insights into its mechanisms. Rigorous selection criteria and homogeneous study population...

    Authors: Lenka Vitova, Zdenek Tuma, Jiri Moravec, Milan Kvapil, Martin Matejovic and Jan Mares
    Citation: BMC Nephrology 2017 18:112
  34. Cytokines have been found to be the important mediators during renal graft outcome. Therefore, we designed this study to investigate the role of recipients’ IL-1 β promoter (−511) and IL-1 β exon-5 (+3954) pol...

    Authors: Mohammad Ashraf Bhat, Manzoor Ahmad Parry, Saniya Nissar, Aga Syed Sameer, Imtiyaz A. Bhat, Zafar A. Shah and Roohi Rasool
    Citation: BMC Nephrology 2017 18:111
  35. Propionic acidemia (PA) is a rare but severe recessive autosomal disease, presenting with non specific signs in the first years of life. Prenatal diagnosis is invasive (amniocentesis) and limited to suspect ca...

    Authors: Ségolène Bernheim, Georges Deschênes, Manuel Schiff, Isabelle Cussenot and Olivier Niel
    Citation: BMC Nephrology 2017 18:110
  36. Direct-acting antivirals (DAAs) dramatically improve the treatment of hepatitis C virus (HCV) infections. However, the effects of DAAs on extra-hepatic manifestations such as HCV-associated glomerulonephritis,...

    Authors: Michiko Shimada, Norio Nakamura, Tetsu Endo, Hideaki Yamabe, Masayuki Nakamura, Reiichi Murakami, Ikuyo Narita and Hirofumi Tomita
    Citation: BMC Nephrology 2017 18:109
  37. For peritoneal dialysis patients, the likelihood of conception is low and the probability of getting through the pregnancy successfully is even lower. Almost 60 years after the first reported case of a success...

    Authors: Thiam Seong Christopher Lim, Malini Shanmuganathan, Irene Wong and Bak Leong Goh
    Citation: BMC Nephrology 2017 18:108
  38. Different measures of non-adherence to immunosuppressant (IS) medication have been found to be associated with rejection episodes after successful transplantation. The aim of the current study was to investiga...

    Authors: Jennifer Scheel, Sandra Reber, Lisa Stoessel, Elisabeth Waldmann, Sabine Jank, Kai-Uwe Eckardt, Franziska Grundmann, Frank Vitinius, Martina de Zwaan, Anna Bertram and Yesim Erim
    Citation: BMC Nephrology 2017 18:107
  39. Alport syndrome and ANCA-associated vasculitis are both rare diseases. The co-existence of these two conditions has never been reported. There is no obvious pathogenic link between these two glomerular disease...

    Authors: Valentine Gillion, Michel Jadoul, Selda Aydin and Nathalie Godefroid
    Citation: BMC Nephrology 2017 18:105
  40. We attempted to describe the clinical features and determine the factors associated with renal survival in idiopathic membranous nephropathy (iMN) patients with nephrotic syndrome (NS) and to determine the fac...

    Authors: Hyuk Huh, Hajeong Lee, Jung Pyo Lee, Dong Ki Kim, Sohee Oh, Yun Kyu Oh, Yon Su Kim and Chun Soo Lim
    Citation: BMC Nephrology 2017 18:104
  41. Although hyperuricemia is common after orthotopic liver transplantation (OLT), its relationship to mortality, progressive kidney disease, or the development of end stage renal disease (ESRD) is not well-descri...

    Authors: Joseph C. Longenecker, Sana Waheed, Ghassan Bandak, Christine A. Murakami, Blaithin A. McMahon, Allan C. Gelber and Mohamed G. Atta
    Citation: BMC Nephrology 2017 18:103
  42. Contrast induced nephropathy (CIN) is the commonest cause of iatrogenic renal injury and its incidence has increased with the advent of complex endovascular procedures. Evidence suggests that ascorbic acid (AA...

    Authors: K. Rollins, A. Noorani, L. Janeckova, T. Jones, M. Griffiths, M. P. Baker and J. R. Boyle
    Citation: BMC Nephrology 2017 18:101
  43. Nail-patella syndrome (NPS) is an autosomal dominant disorder caused by mutations in the LMX1B gene and is characterized by nail dysplasia, skeletal abnormalities, and nephropathy. We herein report a case of s...

    Authors: Tomohiro Nakata, Ryo Ishida, Yuu Mihara, Atsuko Fujii, Yoshimoto Inoue, Tetsuro Kusaba, Tsuyoshi Isojima, Yutaka Harita, Chiaki Kanda, Sachiko Kitanaka and Keiichi Tamagaki
    Citation: BMC Nephrology 2017 18:100
  44. The variability of visit-to-visit (VVV) in systolic blood pressure (SBP) and diastolic blood pressure (DBP) is proved as a predictor of renal function deterioration in patients with non-diabetic chronic kidney...

    Authors: Chi-Hsiao Yeh, Hsiu-Chin Yu, Tzu-Yen Huang, Pin-Fu Huang, Yao-Chang Wang, Tzu-Ping Chen and Shun-Ying Yin
    Citation: BMC Nephrology 2017 18:99
  45. TGF-β is induced in the vasculature with aging suggesting that high plasma TGF-β levels may be a risk factor for chronic kidney disease (CKD) in older adults.

    Authors: Tapan Mehta, Petra Buzkova, Jorge R. Kizer, Luc Djousse, Michel Chonchol, Kenneth J. Mukamal, Michael Shlipak, Joachim H. Ix and Diana Jalal
    Citation: BMC Nephrology 2017 18:98

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