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  1. Reliable and timely detection of acute rejection in renal transplant patients is important to preserve the allograft function and to prevent premature allograft failure. The current gold standard for the rejec...

    Authors: Antonia Zapf, Wilfried Gwinner, Annika Karch, Jochen Metzger, Hermann Haller and Armin Koch
    Citation: BMC Nephrology 2015 16:153
  2. Genetic renal diseases (GRD) are a heterogeneous and incompletely understood group of disorders accounting for approximately 10 % of those diagnosed with kidney disease. The advent of Next Generation sequencin...

    Authors: Andrew Mallett, Chirag Patel, Barbara Maier, Julie McGaughran, Michael Gabbett, Minoru Takasato, Anne Cameron, Peter Trnka, Stephen I. Alexander, Gopala Rangan, Michel C. Tchan, Georgina Caruana, George John, Cathy Quinlan, Hugh J. McCarthy, Valentine Hyland…
    Citation: BMC Nephrology 2015 16:152
  3. It is sometimes challenging to diagnose unsusual cases of fibrillary glomerulonephritis (FGN) and immunotactoid glomerulopathy (ITG), the rare causes of nephrotic syndrome.

    Authors: Ikuyo Narita, Michiko Shimada, Takeshi Fujita, Reiichi Murakami, Masayuki Nakamura, Norio Nakamura, Hideaki Yamabe and Ken Okumura
    Citation: BMC Nephrology 2015 16:151
  4. Compared to others, dialysis patients who are socioeconomically disadvantaged or Black are less likely to receive education about deceased donor kidney transplant (DDKT) and living donor kidney transplant (LDK...

    Authors: Amy D. Waterman, Anna-Michelle M. McSorley, John D. Peipert, Christina J. Goalby, Leanne J. Peace, Patricia A. Lutz and Jessica L. Thein
    Citation: BMC Nephrology 2015 16:150
  5. Kidney stone disease has been associated with reduced kidney function and chronic kidney disease (CKD). The objective of the study was to examine kidney function, body mass index (BMI) and the prevalence of ca...

    Authors: Vaka K. Sigurjonsdottir, Hrafnhildur L. Runolfsdottir, Olafur S. Indridason, Runolfur Palsson and Vidar O. Edvardsson
    Citation: BMC Nephrology 2015 16:149
  6. Fractalkine (FKN) is involved in the occurrence and development of human lupus nephritis. It is known to be upregulated by lipopolysaccharide (LPS) as a stimulus in vivo. MRL/lpr mice have been used as an in vivo

    Authors: Yanwu You, Yueqiu Qin, Xu Lin, Fafen Yang, Jun Li, Suren R. Sooranna and Liao Pinhu
    Citation: BMC Nephrology 2015 16:148
  7. Unfractionated heparin is the most common anticoagulant used in haemodialysis (HD), although it has many potential adverse effects. Citrate dialysate (CD) has an anticoagulant effect which may allow reduction ...

    Authors: Davina J. Tai, Kelvin Leung, Pietro Ravani, Robert R. Quinn, Nairne Scott-Douglas and Jennifer M. MacRae
    Citation: BMC Nephrology 2015 16:147
  8. Some patients with chronic kidney disease do not respond adequately to erythropoiesis-stimulating agent (ESA) treatment; these patients are referred to as ESA hyporesponders. There is no widely accepted contem...

    Authors: Scott P. Sibbel, Carol E. Koro, Steven M. Brunelli and Alexander R. Cobitz
    Citation: BMC Nephrology 2015 16:144
  9. Cardiovascular complications are the leading cause of mortality in patients with end-stage kidney disease. Research indicates that the Mediterranean diet is protective of cardiovascular disease in the general ...

    Authors: Erica Bessell, Matthew D. Jose and Charlotte McKercher
    Citation: BMC Nephrology 2015 16:143
  10. Burn patients with AKI have a higher mortality, rapid diagnosis and early treatment of AKI are necessary. Recent studies have demonstrated that urinary KIM-1 and IL-18 are potential biomarkers of early-stage A...

    Authors: Hongqi Ren, Xuan Zhou, Deshu Dai, Xiang Liu, Liangxi Wang, Yifang Zhou, Xiaomei Luo and Qing Cai
    Citation: BMC Nephrology 2015 16:142
  11. Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterised by progressive renal cyst formation leading to renal failure in the majority of patients. The likelihood and rate of ADP...

    Authors: Claire Woon, Ashleigh Bielinski-Bradbury, Karl O’Reilly and Paul Robinson
    Citation: BMC Nephrology 2015 16:140
  12. Seasonal mortality differences have been reported in US hemodialysis (HD) patients. Here we examine the effect of seasons on mortality, clinical and laboratory parameters on a global scale.

    Authors: Adrian M. Guinsburg, Len A. Usvyat, Michael Etter, Xiaoqi Xu, Stephan Thijssen, Daniele Marcelli, Bernard Canaud, Cristina Marelli, Claudia Barth, Yuedong Wang, Paola Carioni, Frank M. van der Sande, Peter Kotanko and Jeroen P. Kooman
    Citation: BMC Nephrology 2015 16:139
  13. A noninvasive system for determining left ventricular (LV) filling pressure may help to improve personalized fluid removal goals in hemodialysis patients. We previously showed that the change in photoplethysmo...

    Authors: Panagis Galiatsatos, Kapil Parakh, Jennifer Monti, Sumeska Thavarajah, Harriet Aneke-Ogbu, Amaris Watson, Daniel Kim, Nae-Yuh Wang, Tariq Shafi and Harry A. Silber
    Citation: BMC Nephrology 2015 16:138
  14. Low mean arterial pressure (MAP) can cause low renal blood flow and damage the kidneys. However, in the general population, it remains unclear whether or not decline in renal function is related to MAP. The pr...

    Authors: Hongmei Yang, Xiaofan Guo, Xingang Zhang, Zhao Li, Shasha Yu, Liqiang Zheng, Wenna Li, Ying Zhou and Yingxian Sun
    Citation: BMC Nephrology 2015 16:137
  15. Observational data suggest that serum magnesium (Mg) concentration is inversely related to vascular calcification and hyperparathyroidism among patients with end-stage renal disease (ESRD). In recent years, th...

    Authors: Paraish S. Misra, Ahsan Alam, Mark L. Lipman and Sharon J. Nessim
    Citation: BMC Nephrology 2015 16:136
  16. Anemia is a common disorder in CKD patients. It is largely attributed to decreased erythropoietin (EPO) production and iron deficiency. Therefore, besides EPO, therapy includes iron replenishment. However, the...

    Authors: Zaher Armaly, Amir Abd El Qader, Adel Jabbour, Kamal Hassan, Rawi Ramadan, Abdalla Bowirrat and Bishara Bisharat
    Citation: BMC Nephrology 2015 16:135
  17. Uremic neuropathy is a common complication in patients with end stage kidney disease. Its pathogenesis has been attributed to accumulation of uremic toxins. Kidney transplantation has been the best therapeutic...

    Authors: Sassan Ghazan-Shahi, Timothy Jee Kam Koh and Christopher T. Chan
    Citation: BMC Nephrology 2015 16:134
  18. Despite its long-standing status as the diagnostic “gold standard”, the renal transplant biopsy is limited by a fundamental dependence on descriptive, empirically-derived consensus classification. The recent s...

    Authors: Benjamin Adam and Michael Mengel
    Citation: BMC Nephrology 2015 16:132
  19. Higher left ventricular mass (LV) strongly predicts cardiovascular mortality in hemodialysis patients. Although several parameters of preload and afterload have been associated with higher LV mass, whether the...

    Authors: Esther D. Kim, Stephen M. Sozio, Michelle M. Estrella, Bernard G. Jaar, Tariq Shafi, Lucy A. Meoni, Wen Hong Linda Kao, Joao A. C. Lima and Rulan S. Parekh
    Citation: BMC Nephrology 2015 16:131
  20. Chronic kidney disease (CKD) is associated with dyslipidemia, but the role of atherogenic lipid fractions in CKD progression remains unclear. Here we assess whether baseline plasma levels of lipoprotein(a) [Lp...

    Authors: Jennie Lin, Sumeet A. Khetarpal, Karen Terembula, Muredach P. Reilly and F. Perry Wilson
    Citation: BMC Nephrology 2015 16:130
  21. Vitamin D deficiency is highly prevalent in dialysis patients. Whether substitution of native vitamin D in these patients is beneficial is a matter of ongoing discussion, as is the optimal dosing schedule. The...

    Authors: Emanuel Zitt, Hannelore Sprenger-Mähr, Michael Mündle and Karl Lhotta
    Citation: BMC Nephrology 2015 16:128
  22. Sustained low efficiency dialysis (SLED) is increasingly used as a renal replacement modality in critically ill patients with acute kidney injury (AKI) and hemodynamic instability. SLED may reduce the hemodyna...

    Authors: Abhijat Kitchlu, Neill Adhikari, Karen E. A. Burns, Jan O. Friedrich, Amit X. Garg, David Klein, Robert M. Richardson and Ron Wald
    Citation: BMC Nephrology 2015 16:127
  23. Chronic kidney disease is a risk factor for development of cardiovascular diseases. Cardiovascular diseases are the primary cause of morbidity and mortality in patients with chronic kidney disease. There is li...

    Authors: Christopher Babua, Robert Kalyesubula, Emmy Okello, Barbara Kakande, Erias Sebatta, Michael Mungoma and Charles Mondo
    Citation: BMC Nephrology 2015 16:126
  24. Telemedicine has emerged as an alternative mode of health care delivery over the last decade. To date, there is very limited published information in the field of telehealth and paediatric nephrology. The aim ...

    Authors: Peter Trnka, Megan M. White, William D. Renton, Steven J. McTaggart, John R. Burke and Anthony C. Smith
    Citation: BMC Nephrology 2015 16:125
  25. Although adiponectin levels have been reported to be correlated with albuminuria, this issue remains unresolved in non-diabetic hypertensive subjects, particularly when urinary adiponectin is considered.

    Authors: Seung Seok Han, Eunjin Bae, Shin Young Ahn, Sejoong Kim, Jung Hwan Park, Sung Joon Shin, Sang Ho Lee, Bum Soon Choi, Ho Jun Chin, Chun Soo Lim, Suhnggwon Kim and Dong Ki Kim
    Citation: BMC Nephrology 2015 16:123
  26. Hemodialysis is an increasingly common treatment in Vietnam as the diagnosis of end stage renal disease continues to rise. To provide appropriate hemodialysis treatment for end-stage renal disease patients, we...

    Authors: Cuong Minh Duong, Dariusz Piotr Olszyna, Phong Duy Nguyen and Mary-Louise McLaws
    Citation: BMC Nephrology 2015 16:122
  27. Primary myelofibrosis (PMF) is a type of myeloproliferative neoplasm (MPN) characterized by the predominant proliferation of megakaryocytes and granulocytes in the bone marrow, leading to the deposition of fib...

    Authors: Arun Rajasekaran, Thuy-Trang Ngo, Maen Abdelrahim, William Glass, Amber Podoll, Srdan Verstovsek and Ala Abudayyeh
    Citation: BMC Nephrology 2015 16:121
  28. After the publication of our paper Dunlop et al. “Rationale and design of the Sodium Lowering In Dialysate (SoLID) trial: a randomised controlled trial of low versus standard dialysate sodium concentration dur...

    Authors: Joanna Leigh Dunlop, Alain Charles Vandal, Janak Rashme de Zoysa, Ruvin Sampath Gabriel, Imad Adbi Haloob, Christopher John Hood, Philip James Matheson, David Owen Ross McGregor, Kannaiyan Samuel Rabindranath, David John Semple and Mark Roger Marshall
    Citation: BMC Nephrology 2015 16:120
  29. There currently is a need for a non-invasive measure of renal fibrosis. We aim to explore whether shear wave elastography (SWE)-derived estimates of tissue stiffness may serve as a non-invasive biomarker that ...

    Authors: Anthony E. Samir, Andrew S. Allegretti, Qingli Zhu, Manish Dhyani, Arash Anvari, Dorothy A. Sullivan, Caitlin A. Trottier, Sarah Dougherty, Winfred W. Williams, Jodie L. Babitt, Julia Wenger, Ravi I. Thadhani and Herbert Y. Lin
    Citation: BMC Nephrology 2015 16:119
  30. Denosumab and abiraterone were approved by the United States Food and Drug Administration in 2011 for the treatment of metastatic castration-resistant prostate cancer. Neither denosumab nor abiraterone is know...

    Authors: Javier A. Neyra, Natalia A. Rocha, Rhea Bhargava, Omkar U. Vaidya, Allen R. Hendricks and Aylin R. Rodan
    Citation: BMC Nephrology 2015 16:118
  31. Chronic kidney disease (CKD) is a global public health problem that disproportionally affects people of African ethnicity. We assessed the prevalence and determinants of CKD and albuminuria in urban and rural ...

    Authors: Francois Folefack Kaze, Diane Taghin Meto, Marie-Patrice Halle, Jeanne Ngogang and Andre-Pascal Kengne
    Citation: BMC Nephrology 2015 16:117
  32. Whether phosphate itself has nephrotoxicity in patients with chronic kidney disease (CKD) is controversial, although phosphate excretion into urine may cause tubular damage in rat models. To evaluate actual ph...

    Authors: Tomoki Kawasaki, Yoshitaka Maeda, Hisazumi Matsuki, Yuko Matsumoto, Masanobu Akazawa and Tamaki Kuyama
    Citation: BMC Nephrology 2015 16:116
  33. Vascular access-related infections and septicemia are the main causes of infections among hemodialysis patients, the majority of them caused by Staphylococcus species. Acetylsalicylic acid (ASA) has recently b...

    Authors: Hind Harrak, Isabelle Normand, Rachel Grinker, Naoual Elftouh, Louis-Philippe Laurin and Jean-Philippe Lafrance
    Citation: BMC Nephrology 2015 16:115
  34. The silent progression of chronic kidney diseases (CKD) and its association with other chronic diseases, and high treatment costs make it a great public health concern worldwide. The population burden of CKD i...

    Authors: Elizabeth R. Francis, Chin-Chi Kuo, Antonio Bernabe-Ortiz, Lisa Nessel, Robert H. Gilman, William Checkley, J. Jaime Miranda and Harold I. Feldman
    Citation: BMC Nephrology 2015 16:114
  35. Greater interdialytic weight gain (IDWG) is associated with risk of all-cause mortality and hospitalization. Dialysis patients are also at greater risk of cardiovascular (CV) events than patients without kidne...

    Authors: Claudia Cabrera, Steven M. Brunelli, David Rosenbaum, Emmanuel Anum, Karthik Ramakrishnan, Donna E. Jensen, Nils-Olov Stålhammar and Bergur V. Stefánsson
    Citation: BMC Nephrology 2015 16:113
  36. It is unclear how modifications in the way to calculate serum creatinine (sCr) increase and in the cut-off value applied, influences the prognostic value of Acute Kidney Injury (AKI). We wanted to evaluate whe...

    Authors: Jill Vanmassenhove, Norbert Lameire, Annemieke Dhondt, Raymond Vanholder and Wim Van Biesen
    Citation: BMC Nephrology 2015 16:112
  37. Patients with resistant focal segmental glomerulosclerosis (FSGS) who are unresponsive to corticosteroids and other immunosuppressive agents are at very high risk of progression to end stage kidney disease. In...

    Authors: Howard Trachtman, Suzanne Vento, Emily Herreshoff, Milena Radeva, Jennifer Gassman, Daniel T. Stein, Virginia J. Savin, Mukut Sharma, Jochen Reiser, Changli Wei, Michael Somers, Tarak Srivastava and Debbie S. Gipson
    Citation: BMC Nephrology 2015 16:111
  38. Chronic hepatitis B virus (HBV) infection and chronic kidney disease (CKD) have high prevalences in Taiwan and worldwide. However, the association of untreated chronic hepatitis B virus (HBV) infection with ch...

    Authors: Yi-Chun Chen, Yu-Chieh Su, Chung-Yi Li and Shih-Kai Hung
    Citation: BMC Nephrology 2015 16:110
  39. Malnutrition, inflammation, and atherosclerosis (MIA) syndrome is associated with a high mortality rate in patients with end-stage renal disease. However, the clinical relevance of MIA syndrome in kidney trans...

    Authors: Jin Ho Hwang, Jiwon Ryu, Jung Nam An, Clara Tammy Kim, Hyosang Kim, Jaeseok Yang, Jongwon Ha, Dong Wan Chae, Curie Ahn, In Mok Jung, Yun Kyu Oh, Chun Soo Lim, Duck-Jong Han, Su-Kil Park, Yon Su Kim, Young Hoon Kim…
    Citation: BMC Nephrology 2015 16:109
  40. Autoimmune haemolytic anaemia (AIHA) is a rare complication following kidney transplantation and usually occurs early in its course. It is characterised by autoantibodies or alloantibodies directed against red...

    Authors: Alexander J Hamilton, Lynsey H Webb, Jennifer K Williams, Richard J D’Souza, Loretta SP Ngu and Jason Moore
    Citation: BMC Nephrology 2015 16:108
  41. Coronary artery calcification (CAC) is associated with cardiovascular mortality in end-stage renal disease (ESRD) patients. The present study aimed to identify modifiable risk factors for CAC progression in pe...

    Authors: Da Shang, Qionghong Xie, Xiaolin Ge, Huanqing Yan, Jing Tian, Dingwei Kuang, Chuan-Ming Hao and Tongying Zhu
    Citation: BMC Nephrology 2015 16:107
  42. Global longitudinal strain (GLS) has emerged as a superior method for detecting left ventricular (LV) systolic dysfunction compared to ejection fraction (EF) on the basis that it is less operator dependent and...

    Authors: Rathika Krishnasamy, Carmel M. Hawley, Tony Stanton, Elaine M. Pascoe, Katrina L. Campbell, Megan Rossi, William Petchey, Ken-Soon Tan, Kassia S. Beetham, Jeff S. Coombes, Rodel Leano, Brian A. Haluska and Nicole M. Isbel
    Citation: BMC Nephrology 2015 16:106
  43. Recent studies suggest discrepancies between patients and providers around perceptions of hemodialysis prognosis. Such data are lacking for continuous renal replacement therapy (CRRT). We aim to assess patient...

    Authors: Andrew S. Allegretti, Gregory Hundemer, Rajeev Chorghade, Katherine Cosgrove, Ednan Bajwa and Ishir Bhan
    Citation: BMC Nephrology 2015 16:105
  44. Rates of medication non-adherence in dialysis patients are high, and improving adherence is likely to improve outcomes. Few data are available regarding factors associated with medication adherence in dialysis...

    Authors: Trudi Aspden, Martin J Wolley, Tian M Ma, Edwin Rajah, Samantha Curd, Dharni Kumar, Sophia Lee, Krenare Pireva, Olita Taule’alo, Porsche Tiavale, Angela L Kam, Jun S Suh, Julia Kennedy and Mark R Marshall
    Citation: BMC Nephrology 2015 16:102

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