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  1. Nephrotic syndrome is one of the most commonly diagnosed kidney diseases in childhood and its progressive forms can lead to chronic kidney disease (CKD) and/or end-stage renal disease (ESRD). There have been f...

    Authors: Neesha Hussain, J Anastasia Zello, Jovanka Vasilevska-Ristovska, Tonny M Banh, Viral P Patel, Pranali Patel, Christopher D Battiston, Diane Hebert, Christoph P B Licht, Tino D Piscione and Rulan S Parekh
    Citation: BMC Nephrology 2013 14:25
  2. Anaemia is a known risk factor for cardiovascular disease and treating anaemia in chronic kidney disease (CKD) may improve outcomes. However, little is known about the scope to improve primary care management ...

    Authors: Olga Dmitrieva, Simon de Lusignan, Iain C Macdougall, Hugh Gallagher, Charles Tomson, Kevin Harris, Terry Desombre and David Goldsmith
    Citation: BMC Nephrology 2013 14:24
  3. Galectin-9 (Gal-9) induces apoptosis in activated T helper 1 (TH1) cells as a ligand for T cell immunoglobulin mucin-3 (Tim-3). Gal-9 also inhibits the G1 phase cell cycle arrest and hypertrophy in db/db mice, th...

    Authors: Yuko Kurose, Jun Wada, Motoko Kanzaki, Sanae Teshigawara, Atsuko Nakatsuka, Kazutoshi Murakami, Kentaro Inoue, Takahiro Terami, Akihiro Katayama, Mayu Watanabe, Chigusa Higuchi, Jun Eguchi, Nobuyuki Miyatake and Hirofumi Makino
    Citation: BMC Nephrology 2013 14:23
  4. Fibroblast growth factor 23 (FGF23) is an important hormone in the regulation of phosphate metabolism. It is unclear whether FGF23 is associated with carotid artery calcification (CAAC) in predialysis patients...

    Authors: Masaru Nakayama, Yoshiki Kaizu, Masaharu Nagata, Yoriko Ura, Hirofumi Ikeda, Sho Shimamoto and Kazuyoshi Kuma
    Citation: BMC Nephrology 2013 14:22
  5. Family members of patients with end stage renal disease were reported to have an increased prevalence of chronic kidney disease (CKD). However, studies differentiated genetic and non-genetic family members are...

    Authors: Xianglei Kong, Li Liu, Li Zuo, Ping Yuan, Zhongxin Li, Wenge Li, Meishun Cai, Xiangmei Chen, Aili Jiang, Gang Long, Jinsheng Xu, Hongli Lin, Shixiang Wang, Wen Huang, Yiping Wang, Yidan Guo…
    Citation: BMC Nephrology 2013 14:19
  6. Recently, acetate-free citrate containing dialysate (A(−)D) was developed. We have already reported about the significant effect of A(−)D on metabolic acidosis, anemia, and malnutrition in maintenance hemodial...

    Authors: Takahiro Kuragano, Minoru Furuta, Mana Yahiro, Aritoshi Kida, Yoshinaga Otaki, Yukiko Hasuike, Akihide Matsumoto and Takeshi Nakanishi
    Citation: BMC Nephrology 2013 14:18
  7. AKI is common following liver transplantation and is associated with significant morbidity and mortality. Biomarkers of AKI have not been well established in this setting but are needed to help guide patient c...

    Authors: Jeffrey C Sirota, Angela Walcher, Sarah Faubel, Alkesh Jani, Kim McFann, Prasad Devarajan, Connie L Davis and Charles L Edelstein
    Citation: BMC Nephrology 2013 14:17
  8. S100A12 protein is an endogenous receptor ligand for advanced glycation end products. In this study, the plasma S100A12 level was assessed as an independent predictor of mortality, and its utility in clinical ...

    Authors: Yayoi Shiotsu, Yasukiyo Mori, Masato Nishimura, Tsuguru Hatta, Naoki Imada, Noboru Maki, Kumiko Iida, Noriyuki Iwamoto, Eiko Matsuoka, Keiichi Tamagaki and Atsushi Kosaki
    Citation: BMC Nephrology 2013 14:16
  9. There are no prior studies that have estimated the risk of upper gastrointestinal bleeding (UGIB) among the dialysis population relative to the general population. The aim of this study was to examine the risk...

    Authors: Chien-Chun Kuo, Hsin-Wei Kuo, I-Ming Lee, Chien-Te Lee and Chun-Yuh Yang
    Citation: BMC Nephrology 2013 14:15
  10. Marked hyperphosphatemia, hyperparathyroidism and 25-hydroxyvitamin D deficiency are associated with mortality in dialysis patients. Such data in chronic kidney disease stage 2–4 population are limited. It has...

    Authors: Kamonwan Chartsrisak, Kotcharat Vipattawat, Montira Assanatham, Arkom Nongnuch, Atiporn Ingsathit, Somnuek Domrongkitchaiporn, Vasant Sumethkul and Sinee Distha-Banchong
    Citation: BMC Nephrology 2013 14:14
  11. Rifampin is one of the most important drugs in first-line therapies for tuberculosis. The renal toxicity of rifampin has been reported sporadically and acute tubulointerstitial nephritis (ATIN) is a frequent h...

    Authors: Hong Ki Min, Eun Oh Kim, Sang Ju Lee, Yoon Kyung Chang, Kwang Sun Suh, Chul Woo Yang, Suk Young Kim and Hyeon Seok Hwang
    Citation: BMC Nephrology 2013 14:13
  12. Previous studies have demonstrated Aboriginals are less likely to receive a renal transplant in comparison to Caucasians however whether this applies to the entire population or specific subsets remains unclea...

    Authors: Steven Promislow, Brenda Hemmelgarn, Claudio Rigatto, Navdeep Tangri, Paul Komenda, Leroy Storsley, Karen Yeates, Julie Mojica and Manish M Sood
    Citation: BMC Nephrology 2013 14:11
  13. Process of accelerated atherosclerosis specific for uremia increases cardiovascular risk in patients with chronic kidney disease (CKD) and may be influenced by the different structure of arteries. The study as...

    Authors: Przemysław Pencak, Beata Czerwieńska, Rafał Ficek, Katarzyna Wyskida, Agata Kujawa-Szewieczek, Magdalena Olszanecka-Glinianowicz, Andrzej Więcek and Jerzy Chudek
    Citation: BMC Nephrology 2013 14:10
  14. Little is known regarding the types of information African American and non-African American patients with chronic kidney disease (CKD) and their families need to inform renal replacement therapy (RRT) decisions.

    Authors: Nicole DePasquale, Patti L Ephraim, Jessica Ameling, Lapricia Lewis-Boyér, Deidra C Crews, Raquel C Greer, Hamid Rabb, Neil R Powe, Bernard G Jaar, Luis Gimenez, Priscilla Auguste, Mollie Jenckes and L Ebony Boulware
    Citation: BMC Nephrology 2013 14:9
  15. Diabetes is an important reason for end-stage renal failure and diabetic foot wounds worsen the life qualities of these patients. Protein and amino acid support accelerates the wound healing. The purpose of th...

    Authors: Savas Sipahi, Ozkan Gungor, Mehmet Gunduz, Mehmet Cilci, Mustafaa Cahit Demirci and Ali Tamer
    Citation: BMC Nephrology 2013 14:8
  16. Pain is a negative factor in the recovery process of postoperative patients, causing pulmonary alterations and complications and affecting functional capacity. Thus, it is plausible to introduce transcutaneous...

    Authors: Thiago Tafarel Galli, Luciana Dias Chiavegato, Nathália Risso Santiago and Richard Eloin Liebano
    Citation: BMC Nephrology 2013 14:7
  17. IgA nephropathy (IgAN) is the most common glomerulonephritis, which may also coexist with other diseases. We present two patients with an unusual coincidence of IgAN and Fabry disease (FD).

    Authors: Dita Maixnerová, Vladimír Tesař, Romana Ryšavá, Jana Reiterová, Helena Poupětová, Lenka Dvořáková, Lubor Goláň, Michaela Neprašová, Jana Kidorová, Miroslav Merta and Eva Honsová
    Citation: BMC Nephrology 2013 14:6
  18. Chronic kidney disease (CKD) poses a financial burden on patients and their households. This descriptive study measures the prevalence of economic hardship and out-of-pocket costs in an Australian CKD population.

    Authors: Beverley M Essue, Germaine Wong, Jeremy Chapman, Qiang Li and Stephen Jan
    Citation: BMC Nephrology 2013 14:5
  19. Metabolic acidosis leads to chronic kidney disease (CKD) progression. The guidelines recommend a lower limit of serum bicarbonate level, but no upper limit. For serum bicarbonate level to be clinically useful ...

    Authors: Eiichiro Kanda, Masumi Ai, Masayuki Yoshida, Renjiro Kuriyama and Tatsuo Shiigai
    Citation: BMC Nephrology 2013 14:4
  20. Hemolytic and uremic syndrome (HUS) diagnosis involves association of non immune hemolytic anemia, thrombocytopenia, and renal failure. HUS without thrombocytopenia has been observed, we call it partial HUS. I...

    Authors: Marion Sallée, Khalil Ismail, Fadi Fakhouri, Henri Vacher-Coponat, Julie Moussi-Francés, Véronique Frémaux-Bacchi and Stéphane Burtey
    Citation: BMC Nephrology 2013 14:3
  21. Anemia is a common condition in CKD that has been identified as a cardiovascular (CV) risk factor in end-stage renal disease, constituting a predictor of low survival. The aim of this study was to define the o...

    Authors: José Portolés, Jose Luis Gorriz, Esther Rubio, Fernando de Alvaro, Florencio García, Vicente Alvarez-Chivas, Pedro Aranda and Alberto Martinez-Castelao
    Citation: BMC Nephrology 2013 14:2
  22. Urinary tract infection (UTI) occurs in 30%-50% of individuals with autosomal dominant polycystic kidney disease (ADPKD). However, the clinical relevance of asymptomatic pyuria in ADPKD patients remains unknown.

    Authors: Jin Ho Hwang, Hayne Cho Park, Jong Cheol Jeong, Seon ha Baek, Mi Yeun Han, Kitae Bang, Jeong Yeon Cho, Suk Hee Yu, Jaeseok Yang, Kook-Hwan Oh, Young-Hwan Hwang and Curie Ahn
    Citation: BMC Nephrology 2013 14:1
  23. Subacute bacterial endocarditis (SBE) occasionally exhibits positive cytoplasmic anti-neutrophil cytoplasmic antibody (c-ANCA) of the anti-proteinase-3 (PR-3) type. Clinically, it mimics ANCA-associated vascul...

    Authors: Hui Peng, Wen-fang Chen, Chao Wu, Yan-ru Chen, Bo Peng, Sujay Dutta Paudel and Tan-qi Lou
    Citation: BMC Nephrology 2012 13:174
  24. Little is known about the rate of progression to chronic kidney disease (CKD) among hypertensive patients, particularly at the primary care level. This study aims to examine risk factors associated with new on...

    Authors: Yook Chin Chia and Siew Mooi Ching
    Citation: BMC Nephrology 2012 13:173
  25. Health Related Quality of Life (HRQOL) instruments need disease and country specific validation. In Arab countries, there is no specific validated questionnaire for assessment of HRQOL in chronic kidney diseas...

    Authors: Samar Abd ElHafeez, Sunny A Sallam, Zahira M Gad, Carmine Zoccali, Claudia Torino, Giovanni Tripepi, Hala S ElWakil and Noha M Awad
    Citation: BMC Nephrology 2012 13:170
  26. Insulin-like growth factor I (IGF-I), which is mostly carried in blood by IGF-binding protein 3 (IGFBP-3), was associated to the glomerular filtration rate and chronic kidney disease in a multiethnic study amo...

    Authors: Kathleen Dittmann, Henri Wallaschofski, Rainer Rettig, Sylvia Stracke, Karlhans Endlich, Henry Völzke, Matthias Nauck and Nele Friedrich
    Citation: BMC Nephrology 2012 13:169
  27. Renal scintigraphy using 99mTc-mercaptoacetyltriglycine (99mTc-MAG3) is widely used for the assessment of renal function in humans. However, the application of this method to animal models of renal disease is cur...

    Authors: Mohammed N Tantawy, Rosie Jiang, Feng Wang, Keiko Takahashi, Todd E Peterson, Dana Zemel, Chuan-Ming Hao, Hiroki Fujita, Raymond C Harris, Christopher C Quarles and Takamune Takahashi
    Citation: BMC Nephrology 2012 13:168
  28. Evidence is lacking to inform providers’ and patients’ decisions about many common treatment strategies for patients with end stage renal disease (ESRD).

    Authors: L Ebony Boulware, Navdeep Tangri, Patti L Ephraim, Julia J Scialla, Stephen M Sozio, Deidra C Crews, Tariq Shafi, Dana C Miskulin, Jiannong Liu, Wendy St Peter, Bernard G Jaar, Albert W Wu, Neil R Powe, Sankar D Navaneethan and Karen Bandeen-Roche
    Citation: BMC Nephrology 2012 13:167
  29. Endothelin, via endothelin A receptors (ETA), exerts multiple pathologic effects that contribute to disease pathogenesis throughout the body. ETA antagonists ameliorate many experimental diseases and have been...

    Authors: Deborah Stuart, Sara Rees, Stephanie K Woodward, Robert Koesters, Kevin A Strait and Donald E Kohan
    Citation: BMC Nephrology 2012 13:166
  30. Hemodialysis (HD) patients have multiple causes of immune dysfunction and poor immune response to influenza vaccination. We investigated the antibody response rate to a pandemic H1N1/2009 influenza vaccination...

    Authors: Sung Jin Moon, Sang Hun Lee, Young-Ho Byun, Gi Young Yun, Seung Kyu Kim, Baik-Lin Seong, Ah Reum Kim, Eun sun Park, Hyung-Jong Kim, Jung Eun Lee, Sung Kyu Ha, Jae Myun Lee and Hyeong-Cheon Park
    Citation: BMC Nephrology 2012 13:165
  31. The aim of this study was to investigate the characteristics and outcomes of patients receiving renal replacement therapy for end-stage kidney disease (ESKD) secondary to haemolytic uraemic syndrome (HUS).

    Authors: Wen Tang, Janaki Mohandas, Stephen P McDonald, Carmel M Hawley, Sunil V Badve, Neil Boudville, Fiona G Brown, Philip A Clayton, Kathryn J Wiggins, Kym M Bannister, Scott B Campbell and David W Johnson
    Citation: BMC Nephrology 2012 13:164
  32. Visceral adipose tissue-derived serine proteinase inhibitor (vaspin) is an adipokine identified in genetically obese rats that correlates with insulin resistance and obesity in humans. Recently, we found that ...

    Authors: Junko Inoue, Jun Wada, Sanae Teshigawara, Kazuyuki Hida, Atsuko Nakatsuka, Yuji Takatori, Shoichirou Kojo, Shigeru Akagi, Kazushi Nakao, Nobuyuki Miyatake, John F McDonald and Hirofumi Makino
    Citation: BMC Nephrology 2012 13:163
  33. Cardiovascular deaths account for about 40% of all deaths of patients with chronic kidney disease (CKD), particularly those on dialysis, while sudden cardiac death (SCD) might be responsible for as many as 60%...

    Authors: Beata Franczyk-Skóra, Anna Gluba, Maciej Banach, Dariusz Kozłowski, Jolanta Małyszko and Jacek Rysz
    Citation: BMC Nephrology 2012 13:162
  34. Complement activation products are present in atherosclerotic plaques. Recently, binding of complement to elastin and collagen in the aortic wall has been demonstrated, suggesting a role of complement in the d...

    Authors: Florian Knoll, Emanuel Zitt, Denis Intemann and Karl Lhotta
    Citation: BMC Nephrology 2012 13:161
  35. Urinary Ca2+ excretion increases with dietary NaCl. NaCl-induced calciuria may be associated with hypertension, urinary stone formation and osteoporosis, but its mechanism and long-term effects are not fully unde...

    Authors: Midori Sasaki Yatabe, Junichi Yatabe, Kozue Takano, Yuta Murakami, Rina Sakuta, Sadahiko Abe, Hironobu Sanada, Junko Kimura and Tsuyoshi Watanabe
    Citation: BMC Nephrology 2012 13:160
  36. Treatment with selective vitamin D receptor activators such as paricalcitol have been shown to exert an anti-inflammatory effect in patients on hemodialysis, in addition to their action on mineral metabolism a...

    Authors: María Jesús Izquierdo, Mónica Cavia, Pilar Muñiz, Angel LM de Francisco, Manuel Arias, Javier Santos and Pedro Abaigar
    Citation: BMC Nephrology 2012 13:159
  37. The Oxford classification of IgA nephropathy (IgAN) provides a useful tool for prediction of renal prognosis. However, the application of this classification in children with IgAN needs validation in different...

    Authors: Weibo Le, Cai-Hong Zeng, Zhangsuo Liu, Dong Liu, Qing Yang, Rui-Xia Lin, Zheng-Kun Xia, Zhong-Min Fan, Guanghua Zhu, Ying Wu, Hong Xu, Yihui Zhai, Ying Ding, Xiaoqing Yang, Shaoshan Liang, Hao Chen…
    Citation: BMC Nephrology 2012 13:158
  38. An exploration of renal complications of diabetes from the patient perspective is important for developing quality care through the diabetic renal disease care pathway.

    Authors: Emma Wilkinson, Gurch Randhawa, John Feehally, Ken Farrington, Roger Greenwood, Peter Choi and Liz Lightstone
    Citation: BMC Nephrology 2012 13:157
  39. Maintenance hemodialysis (HD) patients universally suffer from excess toxin load. Hemodiafiltration (HDF) has shown its potential in better removal of small as well as large sized toxins, but its efficacy is r...

    Authors: Vaibhav Maheshwari, Lakshminarayanan Samavedham, Gade Pandu Rangaiah, Yijun Loy, Lieng Hsi Ling, Sunil Sethi and Titus Lau Wai Leong
    Citation: BMC Nephrology 2012 13:156
  40. Klotho is a single-pass transmembrane protein, which appears to be implicated in aging. The purpose of the present study was to characterize the relationship between the soluble Klotho level and renal function...

    Authors: Tetsu Akimoto, Hiromichi Yoshizawa, Yuko Watanabe, Akihiko Numata, Tomoyuki Yamazaki, Eri Takeshima, Kana Iwazu, Takanori Komada, Naoko Otani, Yoshiyuki Morishita, Chiharu Ito, Kazuhiro Shiizaki, Yasuhiro Ando, Shigeaki Muto, Makoto Kuro-o and Eiji Kusano
    Citation: BMC Nephrology 2012 13:155
  41. There is a growing awareness in primary care of the importance of identifying patients with chronic kidney disease (CKD) so that they can receive appropriate clinical care; one method that has been widely embr...

    Authors: David H Smith, Jennifer Schneider, Micah L Thorp, Suma Vupputuri, Jessica W Weiss, Eric S Johnson, Adrianne Feldstein, Amanda F Petrik, Xuihai Yang and Susan R Snyder
    Citation: BMC Nephrology 2012 13:154
  42. Sepsis has been identified as the most common cause of acute kidney injury (AKI) in intensive care units. Lipopolysaccharide (LPS) induces the production of several proinflammatory cytokines including tumor ne...

    Authors: Hiroyuki Miyazaki, Jun Morishita, Masaaki Ueki, Kahoru Nishina, Shunichi Shiozawa and Nobuhiro Maekawa
    Citation: BMC Nephrology 2012 13:153
  43. Policies for allocating deceased donor kidneys have recently shifted from allocation based on Human Leucocyte Antigen (HLA) tissue matching in the UK and USA. Newer allocation algorithms incorporate waiting ti...

    Authors: Michael D Clark, Dennis Leech, Anil Gumber, Domenico Moro, Ala Szczepura, Nick West and Robert Higgins
    Citation: BMC Nephrology 2012 13:152
  44. Chronic renal disease is a serious complication of long-term intravenous drug use (IVDU). Recent reports have postulated a changing pattern of underlying nephropathy over the last decades.

    Authors: Oliver Jung, Hans Stefan Haack, Maike Buettner, Christoph Betz, Christoph Stephan, Peter Gruetzmacher, Kerstin Amann and Markus Bickel
    Citation: BMC Nephrology 2012 13:151
  45. Whether paricalcitol (PCT) reduces proteinuria in the presence of intensified inhibition of Renin-Angiotensin-System (RAS) is poorly studied. We evaluated the antiproteinuric effect of PCT in non-dialysis chro...

    Authors: Luca De Nicola, Giuseppe Conte, Domenico Russo, Antonio Gorini and Roberto Minutolo
    Citation: BMC Nephrology 2012 13:150

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