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  1. In March, 2007, a black box warning was issued by the Food and Drug Administration (FDA) to use the lowest possible erythropoiesis-stimulating agents (ESA) doses for treatment of anemia associated with renal d...

    Authors: Mae Thamer, Yi Zhang, Dejian Lai, Onkar Kshirsagar and Dennis Cotter
    Citation: BMC Nephrology 2013 14:172
  2. Hyponatremia is often observed in patients with Legionella pneumonia. However, other electrolyte abnormalities are uncommon and the mechanism remains to be clarified.

    Authors: Naoko Kinoshita-Katahashi, Hirotaka Fukasawa, Sayaka Ishigaki, Shinsuke Isobe, Shiro Imokawa, Yoshihide Fujigaki and Ryuichi Furuya
    Citation: BMC Nephrology 2013 14:171
  3. Monitoring of the appearance of left ventricular hypertrophy (LVH) by echocardiography is currently recommended for in the management of children with End-stage renal disease (ESRD). In order to investigate th...

    Authors: Nikki J Schoenmaker, Johanna H van der Lee, Jaap W Groothoff, Gabrielle G van Iperen, Ingrid ME Frohn-Mulder, Ronald B Tanke, Jaap Ottenkamp and Irene M Kuipers
    Citation: BMC Nephrology 2013 14:170
  4. We established earlier the absolute renal risk (ARR) of dialysis/death (D/D) in primary IgA nephropathy (IgAN) which permitted accurate prospective prediction of final prognosis. This ARR was based on the pote...

    Authors: Hesham Mohey, Blandine Laurent, Christophe Mariat and Francois Berthoux
    Citation: BMC Nephrology 2013 14:169
  5. Some parenteral iron therapies have been found to be associated with hypophosphatemia. The mechanism of the decrease in serum phosphate is unknown. The aim of this study is to examine the effect of IV ferric c...

    Authors: Merche Prats, Ramon Font, Carmen García, Carmen Cabré, Manel Jariod and Alberto Martinez Vea
    Citation: BMC Nephrology 2013 14:167
  6. Pseudohypoaldosteronism type II (PHA II), also referred to as Gordon syndrome, is a rare renal tubular disease that is inherited in an autosomal manner. Though mutations in WNK1 and WNK4 partially account for thi...

    Authors: Shoji Tsuji, Miyoko Yamashita, Gen Unishi, Reiko Takewa, Takahisa Kimata, Kiyoshi Isobe, Motoko Chiga, Shinichi Uchida and Kazunari Kaneko
    Citation: BMC Nephrology 2013 14:166
  7. We previously demonstrated that lovastatin decreases cyst volume and improves kidney function in the Han:SPRD (Cy/+) rat model of ADPKD. Since endothelial dysfunction and inflammatory activity are evident in p...

    Authors: Jelena Klawitter, Iram Zafar, Jost Klawitter, Alexander T Pennington, Jacek Klepacki, Berenice Y Gitomer, Robert W Schrier, Uwe Christians and Charles L Edelstein
    Citation: BMC Nephrology 2013 14:165
  8. Vitamin D receptor activators reduce albuminuria, and may improve survival in chronic kidney disease (CKD). Animal studies suggest that these pleiotropic effects of vitamin D may be mediated by suppression of ...

    Authors: Thomas Larsen, Frank H Mose, Jesper N Bech and Erling B Pedersen
    Citation: BMC Nephrology 2013 14:163
  9. Multi-causality and heterogeneity of phenotypes and genotypes characterize complex diseases. In a database with comprehensive collection of phenotypes and genotypes, we compared the performance of common machi...

    Authors: Ross KK Leung, Ying Wang, Ronald CW Ma, Andrea OY Luk, Vincent Lam, Maggie Ng, Wing Yee So, Stephen KW Tsui and Juliana CN Chan
    Citation: BMC Nephrology 2013 14:162
  10. Recurrent episodes of venous thrombosis have been closely correlated with JAK2 V617F mutation. Upto date, JAK2 gene mutation has not been defined as a prothrombic risk factor in renal transplant recipients. He...

    Authors: Erhan Tatar, Adam Uslu, Ahmet Aykas, Funda Tasli, Ozgur Oztekin and Gulsum Akgun Cagliyan
    Citation: BMC Nephrology 2013 14:161
  11. Angiomyolipomas are benign tumors of the kidney. Typical angiomyolipomas are usually recognized by identifying fat components before any intervention. On the contrary, solid renal masses without evident fatty ...

    Authors: Chin-Li Chen, Shou-Hung Tang, Sheng-Tang Wu, En Meng, Chih-Wei Tsao, Guang-Huan Sun, Dah-Shyong Yu, Sun-Yran Chang and Tai-Lung Cha
    Citation: BMC Nephrology 2013 14:160
  12. In renal patients estimation of GFR is routinely done by means of population-based formulae using serum creatinine levels. For GFR determination in the creatinine-blind regions or in cases of reno-hepatic synd...

    Authors: Sabine Zitta, Walter Schrabmair, Gilbert Reibnegger, Andreas Meinitzer, Doris Wagner, Willibald Estelberger and Alexander R Rosenkranz
    Citation: BMC Nephrology 2013 14:159
  13. In a simulation based on a pharmacokinetic model we demonstrated that increasing the erythropoiesis stimulating agents (ESAs) half-life or shortening their administration interval decreases hemoglobin variabil...

    Authors: Valentina Forni, Giorgia Bianchi, Adam Ogna, Igor Salvadé, Philippe Vuistiner, Michel Burnier and Luca Gabutti
    Citation: BMC Nephrology 2013 14:157
  14. Thrombotic thrombocytopenic purpura (TTP) is frequently associated with renal abnormalities, but there have been few reports about renal abnormalities in patients with hereditary TTP. In particular, little is ...

    Authors: Koki Mise, Yoshifumi Ubara, Masanori Matsumoto, Keiichi Sumida, Rikako Hiramatsu, Eiko Hasegawa, Masayuki Yamanouchi, Noriko Hayami, Tatsuya Suwabe, Junichi Hoshino, Naoki Sawa, Kenichi Ohashi, Koichi Kokame, Toshiyuki Miyata, Yoshihiro Fujimura and Kenmei Takaichi
    Citation: BMC Nephrology 2013 14:156
  15. Achieving target levels of laboratory parameters of bone and mineral metabolism in chronic kidney disease (CKD) patients is important but also difficult in those living with end-stage kidney disease. This stud...

    Authors: István Kiss, Zoltán Kiss, Csaba Ambrus, András Szabó, János Szegedi, József Balla, Erzsébet Ladányi, Botond Csiky, Ottó Árkossy, Marietta Török, Sándor Túri and Imre Kulcsár
    Citation: BMC Nephrology 2013 14:155
  16. About 39,000 patients were newly prescribed renal replacement therapy in Japan in 2011, resulting in a total of more than 300,000 patients being treated with dialysis. This high prevalence of treated end stage...

    Authors: Soichiro Iimori, Yumi Noda, Tomokazu Okado, Shotaro Naito, Takayuki Toda, Yoshiko Chida, Michio Kuwahara, Ryoichi Ando, Yasuhide Nishio, Yoshitaka Maeda, Hiroyuki Tanaka, Teiichi Tamura, Shigeaki Kimoto, Eiichiro Kanda, Seiji Inoshita, Momono Yoshikawa…
    Citation: BMC Nephrology 2013 14:152
  17. Increasing evidence suggests a mechanistic link between the glycemic environment and renal and cardiovascular events, even below the threshold for diabetes. We aimed to assess the association between HbA1c and...

    Authors: Domingo Hernandez, Ana Espejo-Gil, M Rosa Bernal-Lopez, Jose Mancera-Romero, Antonio J Baca-Osorio, Francisco J Tinahones, Ana M Armas-Padron, Pedro Ruiz-Esteban, Armando Torres and Ricardo Gomez-Huelgas
    Citation: BMC Nephrology 2013 14:151
  18. The current literature recognises that left ventricular hypertrophy makes a key contribution to the high rate of premature cardiovascular mortality in dialysis patients. Determining how we might intervene to a...

    Authors: Joanna Leigh Dunlop, Alain Charles Vandal, Janak Rashme de Zoysa, Ruvin Sampath Gabriel, Imad Adbi Haloob, Christopher John Hood, Philip James Matheson, David Owen Ross McGregor, Kannaiyan Samuel Rabindranath, David John Semple and Mark Roger Marshall
    Citation: BMC Nephrology 2013 14:149
  19. The aim of this study was to describe the findings of renal biopsies from a large nephrology center in Iasi, Romania, performed between 2005 and 2010. We compared these findings with our previous ones, from 19...

    Authors: Carmen Volovăt, Irina Cãruntu, Camelia Costin, Alina Stefan, Raluca Popa, Simona Volovăt, Dimitrie Siriopol, Luminita Voroneanu, Ionut Nistor, Liviu Segall and Adrian Covic
    Citation: BMC Nephrology 2013 14:148
  20. Renal dysfunction occurs commonly in patients awaiting orthotopic liver transplantation (OLT) for end-stage liver disease. The use of simultaneous liver-kidney transplantation has increased in the MELD scoring...

    Authors: Jose Iglesias, Elliot Frank, Sushil Mehandru, John M Davis and Jerrold S Levine
    Citation: BMC Nephrology 2013 14:147
  21. Contrast-induced nephropathy (CIN) is the third leading cause of hospital-acquired acute kidney injury, and it is associated with poor long-term clinical outcomes. Although systolic heart failure is a well-kno...

    Authors: Hyang Mo Koo, Fa Mee Doh, Kwang Il Ko, Chan Ho Kim, Mi Jung Lee, Hyung Jung Oh, Seung Hyeok Han, Beom Seok Kim, Tae-Hyun Yoo, Shin-Wook Kang and Kyu Hun Choi
    Citation: BMC Nephrology 2013 14:146
  22. Zinc-alpha2-glycoprotein (AZGP1) is a secreted protein which is synthesized in a variety of cell types. AZGP1 has functionally been implicated in lipid metabolism, the regulation of cell cycling and cancer pro...

    Authors: Inga Sörensen-Zender, Jan Beneke, Bernhard MW Schmidt, Jan Menne, Hermann Haller and Roland Schmitt
    Citation: BMC Nephrology 2013 14:145
  23. Cardiovascular risk is increased in the early stages of chronic kidney disease (CKD) and also found to be ongoing in renal transplant (Rtx) patients. As a sign of atherosclerosis, increased carotid intima-medi...

    Authors: Kultigin Turkmen, Halil Zeki Tonbul, Fatih Mehmet Erdur, Aysun Toker, Zeynep Biyik, Huseyin Ozbiner, Abduzhappar Gaipov, Elvin Enes Gul, Mehmet Kayrak, Yalcin Solak, Orhan Ozbek, Suleyman Turk and Adrian Covic
    Citation: BMC Nephrology 2013 14:144
  24. Cortical perfusion of the renal transplant can be non-invasively assessed by color Doppler ultrasonography. We performed the Dynamic Tissue Perfusion Measurement (DTPM) of the transplant’s renal cortex using c...

    Authors: Thomas Scholbach, Hsin-Kai Wang, An-Hang Yang, Che-Chuan Loong and Tsai-Hong Wu
    Citation: BMC Nephrology 2013 14:143
  25. Placental growth factor [PlGF) is a cardiovascular (CV) risk marker, which is related to left ventricle hypertrophy (LVH) in animal models. Currently there are no data available regarding the possible relation...

    Authors: Martina Peiskerová, Marta Kalousová, Vilem Danzig, Blanka Míková, Magdalena Hodková, Eduard Němeček, Amjad Bani-Hani, David Ambrož, Hana Benáková, Ales Linhart, Tomas Zima and Vladimir Tesař
    Citation: BMC Nephrology 2013 14:142
  26. Temsirolimus has important clinical activity in both untreated and previously treated patients with advanced renal cell carcinoma. Targeted therapy–related stomatitis and mucositis have occurred during targete...

    Authors: Shintaro Fujihara, Hirohito Mori, Hideki Kobara, Takehiro Suenaga, Yuji Hayashida, Mikio Sugimoto, Yoshiyuki Kakehi and Tsutomu Masaki
    Citation: BMC Nephrology 2013 14:141
  27. It is important to ensure an adequate sodium and volume balance in neurosurgical patients in order to avoid the worsening of brain injury.

    Authors: Valeria Corradetti, Pasquale Esposito, Teresa Rampino, Marilena Gregorini, Carmelo Libetta, Francesca Bosio, Teresa Valsania, Eleonora Francesca Pattonieri, Chiara Rocca, Stefania Bianzina and Antonio Dal Canton
    Citation: BMC Nephrology 2013 14:140
  28. Kidney injury molecule-1 (KIM-1) is a biomarker useful for detecting early tubular damage and has been recently reported as a useful marker for evaluating kidney injury in IgA nephropathy (IgAN). We therefore ...

    Authors: Mi Seon Seo, Moo Yong Park, Soo Jeong Choi, Jin Seok Jeon, Hyunjin Noh, Jin Kuk Kim, Dong Cheol Han, Seung Duk Hwang, So Young Jin and Soon Hyo Kwon
    Citation: BMC Nephrology 2013 14:139
  29. Most kidney disorders involve some degree of inflammation, i.e. induction of pro-inflammatory mediators and leukocyte recruitment. But what are the factors that determine inflammation as a trigger or a consequ...

    Authors: Hans-Joachim Anders
    Citation: BMC Nephrology 2013 14:138
  30. Individuals with end-stage renal disease (ESRD) have excess risk of various cancer types. However, the total burden of human papillomavirus-related cancers remains unknown.

    Authors: Lars Skov Dalgaard, Ulrik Fassel, Lars Jørgen Østergaard, Bente Jespersen, Ole Schmeltz Søgaard and Søren Jensen-Fangel
    Citation: BMC Nephrology 2013 14:137
  31. Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication following coronary bypass graft (CABG) surgery. Multi-factorial causes of CSA-AKI involve oxidative stress and inflammation. Er...

    Authors: Adis Tasanarong, Soodkate Duangchana, Sangduen Sumransurp, Boonlawat Homvises and Opas Satdhabudha
    Citation: BMC Nephrology 2013 14:136
  32. Recently, the Kidney Disease: Improving Global Outcomes (KDIGO) group recommended that patients with chronic kidney disease (CKD) be assigned according to stage and composite relative risk on the basis of glom...

    Authors: Masanori Abe, Kazuyoshi Okada, Hiroko Suzuki, Yoshinori Yoshida and Masayoshi Soma
    Citation: BMC Nephrology 2013 14:135
  33. Multiple solutes are retained in uremia, but it is currently unclear which solutes are toxic. Small studies suggest that protein-bound solutes, such as p-cresol sulfate and indoxyl sulfate and intracellular so...

    Authors: Michal L Melamed, Laura Plantinga, Tariq Shafi, Rulan Parekh, Timothy W Meyer, Thomas H Hostetter, Josef Coresh and Neil R Powe
    Citation: BMC Nephrology 2013 14:134
  34. The addition of relevant parameters to acute kidney injury (AKI) criteria might allow better prediction of patient mortality than AKI criteria alone. Here, we evaluated whether inclusion of AKI duration could ...

    Authors: Seung Seok Han, Sejoong Kim, Shin Young Ahn, Jeonghwan Lee, Dong Ki Kim, Ho Jun Chin, Dong-Wan Chae and Ki Young Na
    Citation: BMC Nephrology 2013 14:133
  35. For chronic kidney disease (CKD) patients, national treatment guidelines recommend a low-density lipoprotein cholesterol (LDL-C) goal <100 mg/dL and blood pressure (BP) target <130/80 mmHg. This analysis asses...

    Authors: Andreas Kuznik, Jack Mardekian and Lisa Tarasenko
    Citation: BMC Nephrology 2013 14:132
  36. The number of elderly (≥75 years) patients with end-stage renal disease (ESRD) has increased markedly, including in the Limousin region, which has the oldest population in France. We retrospectively compared o...

    Authors: Florence Glaudet, Carine Hottelart, Julien Allard, Vincent Allot, Frédérique Bocquentin, Rémy Boudet, Béatrice Champtiaux, Jean Pierre Charmes, Monica Ciobotaru, Zara Dickson, Marie Essig, Philippe Honoré, Céline Lacour, Christian Lagarde, Maria Manescu, Pierre Peyronnet…
    Citation: BMC Nephrology 2013 14:131
  37. Complementary and Alternative Medicines (CAMs) are increasingly practiced in the general population; it is estimated that over 30% of patients with chronic diseases use CAMs on a regular basis. CAMs are also u...

    Authors: Martina Ferraresi, Roberta Clari, Irene Moro, Elena Banino, Enrico Boero, Alessandro Crosio, Romina Dayne, Lorenzo Rosset, Andrea Scarpa, Enrica Serra, Alessandra Surace, Alessio Testore, Nicoletta Colombi and Giorgina Barbara Piccoli
    Citation: BMC Nephrology 2013 14:129
  38. The hemodialysis (HD) population has a particularly high incidence of amputation, which is likely associated with decreased tissue oxygenation during HD. However, information about the risk factors leading to ...

    Authors: Shih-Yi Lin, Che-Chen Lin, Chung-Chih Lin, Chi-Jung Chung, Horng-Che Yeh, I-Kuan Wang, I-Wen Ting, Chiu-Chin Huang and Fung-Chang Sung
    Citation: BMC Nephrology 2013 14:128
  39. The increasing incidence and prevalence of chronic kidney disease is an important challenge for health systems around the world. Access for care of the disease in Ethiopia is extremely limited. The main purpos...

    Authors: Tamiru Shibiru, Esayas Kebede Gudina, Belete Habte, Amare Deribew and Tewodros Agonafer
    Citation: BMC Nephrology 2013 14:127
  40. Renal interstitial fibrosis and glomerular sclerosis are hallmarks of diabetic nephropathy (DN) and several studies have implicated members of the WNT pathways in these pathological processes. This study compr...

    Authors: David H Kavanagh, David A Savage, Christopher C Patterson, Amy Jayne McKnight, John K Crean, Alexander P Maxwell and Gareth J McKay
    Citation: BMC Nephrology 2013 14:126
  41. A new histopathological classification of anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis was recently proposed. We evaluated the predictive value of this classification for renal out...

    Authors: Takashi Iwakiri, Shouichi Fujimoto, Kiyoki Kitagawa, Kengo Furuichi, Junya Yamahana, Yunosuke Matsuura, Atsushi Yamashita, Shigehiro Uezono, Yoshiya Shimao, Shuichi Hisanaga, Takeshi Tokura, Takashi Wada, Kazuo Kitamura and Yujiro Asada
    Citation: BMC Nephrology 2013 14:125
  42. Diabetic nephropathy is a growing clinical problem, and the cause for >40% of incident ESRD cases. Unfortunately, few modifiable risk factors are known. The objective is to examine if albuminuria and history o...

    Authors: Douglas Gunzler, Anthony J Bleyer, Robert L Thomas, Alicia O’Brien, Gregory B Russell, Abdus Sattar, Sudha K Iyengar, Charles Thomas, John R Sedor and Jeffrey R Schelling
    Citation: BMC Nephrology 2013 14:124
  43. Canada’s pandemic H1N1 influenza A (pH1N1) outbreak led to a high burden of critical illness. Our objective was to describe the incidence of AKI (acute kidney injury) in these patients and risk factors for AKI...

    Authors: Sean M Bagshaw, Manish M Sood, Jennifer Long, Robert A Fowler and Neill KJ Adhikari
    Citation: BMC Nephrology 2013 14:123

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