Characteristic | N | Non-switchers | Switchers | P |
---|---|---|---|---|
Total | 262 | 197 (75.2%) | 65 (24.8%) | -- |
Demographic | Â | Â | Â | Â |
Mean age at enrollment, years | 262 | 54.7 ± 15.4 | 52.0 ± 13.0 | 0.202 |
Sex (% female) | 262 | 42.1 | 47.7 | 0.433 |
Race (% white) | 262 | 83.8 | 72.3 | 0.042 |
Education (% high school graduate) | 225 | 84.2 | 75.4 | 0.131 |
Employment (% working) | 262 | 28.4 | 20.0 | 0.181 |
Marital Status (% married) | 238 | 68.9 | 62.3 | 0.341 |
Distance from clinic (% >30 miles) | 216 | 28.3 | 28.1 | 0.973 |
Clinical | Â | Â | Â | Â |
Smoking status (% ever smoker) | 227 | 61.5 | 60.7 | 0.914 |
Modality at start, from 2728 (% HD) | 256 | 7.8 | 9.4 | 0.693 |
ICED score (%) | 262 | Â | Â | 0.848 |
   ≤ 1 |  | 50.3 | 46.2 |  |
   2 |  | 25.4 | 27.7 |  |
   3 |  | 24.4 | 26.2 |  |
Diabetes (% diabetic) | 262 | 49.2 | 58.5 | 0.197 |
History of CVD (% positive) | 262 | 52.3 | 41.5 | 0.133 |
History of CHD (% positive) | 262 | 41.1 | 32.3 | 0.207 |
History of CHF (% positive) | 262 | 40.6 | 29.2 | 0.101 |
Primary cause of renal failure (%) | 259 | Â | Â | 0.341 |
   Diabetes mellitus |  | 44.8 | 53.9 |  |
   Hypertension |  | 10.8 | 6.2 |  |
   Glomerulonephritis |  | 44.3 | 40.0 |  |
Late referral (% <4 months) | 198 | 21.7 | 16.4 | 0.404 |
BMI, kg/m2 | 245 | 25.9 ± 5.6 | 28.2 ± 6.0 | 0.006 |
Residual urine output (%) | 186 | Â | Â | 0.018 |
   Not at baseline or follow-up at 1 year |  | 14.6 | 19.6 |  |
   At baseline but not at follow-up at 1 year |  | 17.7 | 33.9 |  |
   At baseline and at follow-up at 1 year |  | 67.7 | 46.4 |  |
Laboratory | Â | Â | Â | Â |
Mean baseline albumin, g/dl | 248 | 3.57 ± 0.44 | 3.64 ± 0.38 | 0.316 |
Mean baseline hemoglobin, g/dl | 246 | 11.3 ± 1.5 | 11.3 ± 1.5 | 0.766 |
Median CRP (IQR), μg/dl | 162 | 2.6 (1.1–6.2) | 3.5 (1.6–5.7) | 0.638 |
Baseline creatinine, g/dl | 252 | 7.08 ± 2.66 | 7.94 ± 2.63 | 0.029 |
Baseline cholesterol, mg/dl | 220 | 207 ± 53 | 210 ± 57 | 0.746 |
Baseline GFR, cc/minute/1.73 m2 | 254 | 10.5 ± 0.26 | 10.3 ± 0.45 | 0.721 |