From: Interventions for renal vasculitis in adults. A systematic review
Study ID | Randomisation method | Allocation concealment | Blinding: Participants | Blinding: Investigators | Blinding: Outcome assessors | Blinding: Data assessors | ITT | % Follow-up |
---|---|---|---|---|---|---|---|---|
Adu 1997 | Computer generated random numbers. Stratified for renal function | A | No | No | No | No | Yes | 100 |
Cole 1992 | computer-generated random numbers after informed consent Stratified by urine volume (< 400 ml/24 h), need for dialysis and > 50% glomeruli sclerosed | B | No | No | Yes | No | No | 97 |
De Groot 2009a | computer generated, performed centrally by permuted blocks of 4, stratified by country and disease. assigned randomly 1:1 to treatments. | A | No | No | No | Yes | Yes | 83 |
Furuta 1998 | NS | B | No | No | NS | NS | Yes | 100 |
Jayne 2007 | NS | B | No | No | NS | NS | Yes | 100 |
Glockner 1988 | By telephone with statistician | B | No | No | NS | NS | No | 84 |
Guillevin 1997 | NS | B | No | No | NS | NS | No | 93 |
Haubitz 1998 | Stratified at diagnosis | B | No | No | NS | NS | No | 84 |
Jayne 2007 | Centrally, block design. Stratified by diagnosis | A | NS | NS | NS | Yes | Yes | 100 |
Mauri 1985 | NS | B | No | No | NS | NS | Yes | 100 |
Pusey 1991 | Stratified for severity according to renal function by random numbers | B | No | No | NS | NS | No | 92 |
Rifle 1980 | NS | B | No | No | NS | NS | No | 82 |
Stegeman 1996 | Stratified by group and then randomized | B | Yes | Yes | Yes | NS | No | 99 |
Stegmayr 1999 | NS | B | No | No | NS | NS | No | 83 |
Hu 2008 | Not stated | B | No | No | No | NS | Yes | 89 |
Jayne 2000 | Central | A | Yes | Yes | Yes | NS | Yes | 100 |
Metzler 2007 | Central | A | No | No | No | No | Yes | 96 |
WGET 2000 | Stratified by disease severity and by centre | A | Yes | Yes | Yes | NS | Yes | 97 |
Pagnoux 2008 | Permuted blocks of six | A | No | No | No | NS | Yes | 100 |
Hiemstra 2009 | NS | NS | No | No | NS | NS | Yes | NS |
RAVE | NS | NS | Yes | Yes | NS | NS | NS | NS |
RITUXVAS | Central randomisation | Yes | No | No | NS | NS | Yes | 100 |