Study Protocol: A Pilot Study to Determine the Safety and Efficacy of Induction-Therapy, De Novo MPA and Delayed mTOR-Inhibition in Liver Transplant Recipients with Impaired Renal Function. PATRON-Study

Table 2 Follow-up and planned interventions for PATRON 07

	Day 0	Day 1	Day 2	Day 3	Day 4	Day 10	Day 14/15	Day 20/21	Day 25/26	Day 30	Month 3	Month 6	Month 12
Medical History ¹	X
Transplant Data	X
eGFR	X	X	X	X	X	X	X	X	X	X	X	X	X
Laboratory ²	X	X	X	X	X	X	X	X	X	X	X	X	X
Ultrasound ³	X	X				X					X	X	X
Rejection ⁴		X	X	X	X	X	X	X	X	X	X	X	X
AE	X	X	X	X	X	X	X	X	X	X	X	X	X
Sirolimus trough levels (4-10 ng/mL)							X	X	X	X	X	X	X

1: focusing on liver disease, infectious history, concomitant renal disease
2: Na, K, creatinine, urea, GOT, GPT, AP, yGT, bilirubin, CHE, LDH, Quick, pTT, Hb, leucocytes, platelets, cholesterole and triglycerides (day 0 and 30)
3: Additional examinations in case of pathologic findings or indication.
4. laboratory signs of rejection (if suspected confirmed by biopsy)

ISSN: 1471-2369