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Table 3 Time weighted analysis in VDRA + −group

From: Effect of vitamin-D analogue on albuminuria in patients with non-dialysed chronic kidney disease stage 4–5: a retrospective single center study

 

Before

After

P

Kidney Function

eGFR (ml/min)

14.8 ± 3.6

12.6 ± 5.5

<0.001

Delta eGFR (ml/min/day)

−0.018 ± 0.032

−0.013 ± 0.020

Ns

U-Albumin (g/d)

1.75 ± 1.64

1.60 ± 1.48

=0.05

Mineral-Bone

S-calcium (mmol/l)

1.15 ± 0.06

1.15 ± 0.07

Ns

S-phosphate (mmol/l)

1.51 ± 0.28

1.62 ± 0.38

Ns

S-PTH (pmol/l)

26.7 ± 11.5

23.8 ± 11.2

Ns

Blood Pressure

Systolic (mmHg)

147 ± 19

147 ± 17

Ns

Diastolic (mmHg)

82 ± 9

84 ± 10

Ns

  1. Time average values of all 24 h urinary collections before and after starting treatment with alfacalcidol in 59 patients with CKD 4–5. Number of urinary collections varied from 1 to 4 before and from 1 to 6 after. The mean time follow up time was 422 days (range 66–1347) before start of alfacalcidol and 364 (72–1196) after. Mean ± SD.
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BMC Nephrology

ISSN: 1471-2369

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