Table 2 Baseline Risk Factors and Associated Mortality Using Unadjusted Cox Proportional Hazard (Cox-PH) and Gray’s Survival Models
From: All-cause and cause-specific mortality associated with diabetes in prevalent hemodialysis patients
Variables | Cox-PH Model | PH test | Grays Model | ||
|---|---|---|---|---|---|
H.R.aEstimate [LL, UL] | P-value | P-value | H.R. Rangeb(min – max) | P-value | |
Diabetes | 1.64 [1.43, 1.87] | <0.01 | 0.05 | 1.46-2.21 | <0.01 |
Age£ | 1.46 [1.38, 1.55] | <0.01 | 0.98 | 1.44-1.50 | <0.01 |
Female sex | 1.01 [0.88, 1.16] | 0.88 | 0.13 | 0.91-1.19 | 0.52 |
Black race | 0.73 [0.64, 0.84] | <0.01 | 0.09 | 0.68-0.93 | <0.01 |
BMI | 0.98 [0.97, 0.99] | <0.01 | 0.28 | 0.96-0.99 | <0.01 |
Yrs of Dialysis | 0.99 [0.97, 1.00] | 0.18 | 0.05 | 0.99-1.01 | 0.08 |
Residual urine output | 0.97 [0.77, 1.22] | 0.80 | 0.05 | 0.73-1.22 | 0.23 |
≥200 ml/day urine | |||||
High Kt/V | 0.95 [0.83, 1.08] | 0.41 | 0.72 | 0.91-0.96 | 0.88 |
High Flux | 0.95 [0.83, 1.08] | 0.41 | 0.15 | 0.87-1.11 | 0.33 |
Access(Cather vs. All other) | 1.91 [1.47, 2.47] | <0.01 | 0.79 | 1.75-2.02 | <0.01 |
Comorbidity ICED Score | 1.57 [1.44, 1.70] | <0.01 | 0.79 | 1.51-1.67 | <0.01 |
Blood Pressure | |||||
Systolic* | 0.97 [0.91, 1.04] | 0.37 | <0.01 | 0.99-1.00 | 0.01 |
Diastolic* | 0.80 [0.75, 0.86] | <0.01 | 0.38 | 0.80-0.87 | <0.01 |
Smoking(Smoked vs. Never) | 1.08 [0.99, 1.18] | 0.09 | 0.03 | 0.95-1.18 | 0.04 |
Calcium (mg/dL) | 0.93 [0.86, 0.99] | 0.03 | 0.08 | 0.85-1.01 | <0.01 |
Phosphorus (mg/dL)* | 0.98 [0.91, 1.05] | 0.55 | 0.49 | 0.95-1.01 | 0.87 |
Total Cholesterol (mg/dL)* | 0.99 [0.92, 1.06] | 0.78 | 0.95 | 0.97-1.02 | 0.95 |
Albumin (mg/dL) | 0.57 [0.52, 0.63] | <0.01 | <0.01 | 0.44-0.66 | <0.01 |