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Figure 1 | BMC Nephrology

Figure 1

From: The effect of lowering salt intake on ambulatory blood pressure to reduce cardiovascular risk in chronic kidney disease (LowSALT CKD study): protocol of a randomized trial

Figure 1

Simplified diagram of the relationship between excess sodium, kidney damage and risk of CVD. Excess sodium in CKD is caused by decreased sodium excretion & high sodium intake (*influenced by food supply and preference – potentially mediated by taste sensitivity). This increases cardiovascular risk not only via altered extracellular volume & blood pressure (BP) but also through direct toxic effects on blood vessels.

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BMC Nephrology

ISSN: 1471-2369

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