Figure 4

Effect of T-5224 on serum cytokines following LPS administration. a, the administration of T-5224 decreased serum IL-1β (132.7 ± 32.3 pg/ml vs. 335.5 ± 85.9 pg/ml). b, IL-6 levels were decreased after T-5224 treatment (44.4 ± 16.6 ng/ml vs. 113.4 ± 29.1 ng/ml) as compared with the LPS group. c, serum IL-10 levels in the T-5224 group were similar to the LPS group (1637.7 ± 402.3 pg/ml vs. 1597.7 ± 471.8 pg/ml) (n = 6–9 per group). **P < 0.01 vs. control group. ##P < 0.01 vs. LPS group.