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Table 1 Clinical characteristics at the time of biopsy and follow-up in 218 pediatric patients with IgA nephropathy

From: Validation of the Oxford classification of IgA nephropathy for pediatric patients from China

 

Current study

Oxford study (Children)

Shima et al. [19]

At time of biopsy

n = 218

n = 59

n = 161

 Age (years)

14 (2–17.9)

13 (4–17.9)

11.7(3.6-19.4)

 Female

35%

25%

37%

 Hypertensive before biopsy

6.5%

NA

NA

 MAP (mm Hg)

88 ± 11

84 ± 10

79 ± 11

 eGFR (ml/min per 1.73 m2)

134 ± 42

120 ± 43

103 ± 30

 Proteinuria (g/day)

1.5(0.5-8.0)

2 (0.5-7.8)

0.7 (0.0–13.7)

 Previous macroscopic hematuria

57%

60%

66%

Follow-up

 Duration of follow-up (months)

56(12–182)

62 (20–268)

54 (12–170)

 50% decline in eGFR or ESRD

12.4%

NA

NA

 MAP (mm Hg)

86 ± 10

86 ± 8

NA

 Proteinuria (g/day)

0.6 (0.1-4.9)

0.9 (0.1–7.0)

NA

 Immunosuppression

56%

48%

16%

 Prednisone

51%

48%

16%

 Others

28.6%

17%

11%

 Treated with RASB

61.5%

56%

NA

  1. Abbreviations: RASB, renin-angiotensin system blockade; eGFR, estimated glomerular filtration rate; MAP, mean arterial pressure; ESRD, end stage renal disease; NA, not available.
  2. Values are expressed as mean ± s.d. or median (range). Calculation of MAP, eGFR, and proteinuria is detailed in the text.