Baseline characteristics | All | MBL ≤500 ng/mL | MBL >500 ng/mL | P-value |
---|---|---|---|---|
 | (n = 246) | (n = 57) | (n = 189) |  |
Age in years, mean (SD) | 75 (9.4) | 74 (10.5) | 75 (9.5) | 0.4 |
Female sex, n (%) | 89 (36) | 24 (42) | 65 (34) | 0.4 |
MBL in ng/mL, median (IQR) | 2150 (560–3794) | 127 (11–330) | 2855 (1701–4347) | n/a |
BMI in kg/m2, median (IQR) | 26 (23–29) | 27 (24–30) | 26 (23–29) | 0.09 |
Contrast medium in mL, median (IQR) | 100 (80–160) | 100 (80–150) | 100 (80–170) | 0.3 |
Medical history | Â | Â | Â | Â |
Hypertension, n (%) | 204 (83) | 48 (84) | 156 (83) | 0.8 |
D.m., n (%) | 90 (37) | 19 (33) | 71 (38) | 0.6 |
Dyslipidemia, n (%) | 145 (59) | 34 (60) | 111 (59) | 1.00 |
Coronary heart disease, n (%) | 143 (58) | 31 (54) | 112 (59) | 0.5 |
CHF, n (%) | 111 (45) | 23 (40) | 88 (47) | 0.5 |
Peripheral artery disease, n (%) | 64 (26) | 11(19) | 53 (28) | 0.2 |
Current smoking, n (%) | 40 (16) | 7 (12) | 33 (17) | 0.4 |
Medication | Â | Â | Â | Â |
ACE-Inhibitor, n (%) | 108 (44) | 23 (40) | 85 (45) | 0.7 |
AT-II-Inhibitor, n (%) | 69 (28) | 13 (23) | 56 (30) | 0.40 |
Diuretics, n (%) | 173 (70) | 41 (72) | 132 (70) | 0.9 |
NSAIDs, n (%) | 8 (3) | 5 (9) | 3 (2) | 0.02 |
Baseline parameters | Â | Â | Â | Â |
Systolic BP in mmHg, median (IQR) | 130 (120–146) | 132 (120–149) | 130 (117–145) | 0.1 |
Diastolic BP in mmHg, median (IQR) | 70 (60–80) | 76 (65–80) | 70 (60–80) | 0.01 |
Creatinine in μmol/L, median (IQR) | 137 (114–162) | 140 (113–154) | 136 (114–164) | 0.9 |
Cystatin C in mg/L, median (IQR) | 1.7 (1.5-2.0) | 1.8 (1.5-2.0) | 1.7 (1.5-2.1) | 0.8 |
eGFR in mL/min/1.73 m2, median (IQR) | 44 (35–52) | 44 (35–51) | 44 (35–53) | 0.8 |
Type of procedure | Â | Â | Â | Â |
Coronary angiogram, n (%) | 110 (45) | 23 (40) | 87 (46) | 0.5 |
PCI, n (%) | 52 (21) | 12 (21) | 40 (21) | 1.00 |
CT scan, n (%) | 110 (45) | 29 (51) | 81 (43) | 0.3 |
Other, n (%) | 26 (11) | 5 (9) | 21 (11) | 0.8 |
Intervention group | Â | Â | Â | Â |
Standard 24 h sodium chloride, n (%) | 85 (35) | 16 (28) | 69 (37) | 0.3 |
7 h sodium bicarbonate, n (%) | 82 (33) | 22 (39) | 60 (32) | 0.3 |
Short-term sodium bicarbonate, n (%) | 79 (32) | 19 (33) | 60 (32) | 0.9 |